Santin (flavonol)
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Santin (flavonol)
Santin is an O-methylated flavonol The O-methylated flavonoids or methoxyflavonoids are flavonoids with methylations on hydroxyl groups (methoxy bonds). O-methylation has an effect on the solubility of flavonoids. Enzymes O-methylated flavonoids formation implies the presence of spe .... It was isolated from '' Tanacetum microphyllum''.Martinez, J., et al. (1997)Isolation of two flavonoids from ''Tanacetum microphyllum'' as PMA-induced ear edema inhibitors.''Journal of Natural Products'' 60(2), 142-44. References O-methylated flavonols Flavonoids found in Asteraceae {{aromatic-stub ...
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O-methylated Flavonol
The O-methylated flavonoids or methoxyflavonoids are flavonoids with methylations on hydroxyl groups (methoxy bonds). O-methylation has an effect on the solubility of flavonoids. Enzymes O-methylated flavonoids formation implies the presence of specific O-methyltransferase (OMT) enzymes which accept a variety of substrates. Those enzymes mediate the O-methylation on a specific hydroxyl group, like on 4' (example in ''Catharanthus roseus'') or 3' (example in rice) positions. Those positions can be ortho, meta, para and there can be a special 3-O-methyltransferase for the 3-OH position. Calamondin orange ('' Citrus mitis'') exhibits all of those activities. Plant enzymes * Apigenin 4'-O-methyltransferase * 8-hydroxyquercetin 8-O-methyltransferase * Isoflavone 4'-O-methyltransferase * Isoflavone 7-O-methyltransferase * Isoliquiritigenin 2'-O-methyltransferase * Isoorientin 3'-O-methyltransferase * Kaempferol 4'-O-methyltransferase * Luteolin O-methyltransferase * Methylquercet ...
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Tanacetum Microphyllum
''Tanacetum microphyllum'' is a species of flowering plant in the aster family, Asteraceae. It is endemic to the Iberian Peninsula.Abad, M. J., et al. (2003)The phytochemical and pharmacological investigations on ''Tanacetum microphyllum''.''Recent Research Developments in Life Sciences'' 1, II. 371-95. The plant has been used for centuries in Spanish traditional medicine as an anti-inflammatory and antirheumatic. Compounds isolated from extracts of the plant include santin, ermanin, centaureidin Centaureidin is an O-methylated flavonol. It can be isolated from '' Tanacetum microphyllum'', ''Achillea millefolium'', ''Brickellia veronicaefolia'', ''Bidens pilosa ''Bidens pilosa'' is an annual species of herbaceous flowering plant in t ..., and hydroxyachillin. References microphyllum Flora of Portugal Flora of Spain Plants described in 1838 Medicinal plants of Europe Endemic flora of the Iberian Peninsula {{Anthemideae-stub ...
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