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Sanaria
Sanaria is a biotechnology company developing vaccines protective against malaria and other infectious diseases as well as related products for use in malaria research. Sanaria's vaccines are based on the use of the sporozoite, sporozoite (SPZ) stage of the malaria parasite, ''Plasmodium,'' as an immunogen, and as a platform technology for liver-vectored gene delivery. SPZ are normally introduced into humans by mosquito bite where they migrate to the liver and further develop to liver stages, and eventually back into the blood stream where the parasite infects red blood cells (RBC) and causes malaria. ''Plasmodium falciparum'' is the species responsible for more than 95% deaths caused by malaria. The WHO estimates there were 249 million clinical cases and 608,000 deaths in 2022 alone. Sanaria has developed the technology to grow and harvest aseptic, purified ''Plasmodium falciparum'' (Pf) SPZ and formulate them as vaccines for human use. Sanaria's first generation vaccine is cal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PfSPZ Vaccine
PfSPZ Vaccine is a metabolically active non-replicating whole sporozoite (SPZ) malaria vaccine being developed by Sanaria against ''Plasmodium falciparum'' (Pf) malaria. Clinical trials have been safe, extremely well tolerated and highly efficacious. The first generation PfSPZ product is attenuated by gamma irradiation; the second generation vaccines PfSPZ-CVac and PfSPZ LARC2 are, respectively, attenuated chemically and genetically. Multiple studies are ongoing with trials of the PfSPZ vaccines. All three products are produced using the same manufacturing process. These products are stored and distributed below -150 °C using liquid nitrogen (LN2) vapor phase (LNVP) freezers and Dry shipper, cryoshippers. History In the first half of the 20th century there were first attempts to protect people from malaria. At the beginning Pasteur's approach of developing bacterial vaccines was used as a big hope in eradication of this fatal disease. But inactivated malaria sporozoites (by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rockville, Maryland
Rockville is a city that serves as the county seat of Montgomery County, Maryland, and is part of the Baltimore–Washington metropolitan area. The 2020 census tabulated Rockville's population at 67,117, making it the fifth-largest community in Montgomery County. Rockville, along with neighboring Gaithersburg and Bethesda, is at the core of the Interstate 270 Technology Corridor which is home to numerous software and biotechnology companies as well as several federal government institutions. The city, one of the major retail hubs in Montgomery County, also has several upscale regional shopping centers. History Early history Situated in the Piedmont region and crossed by three creeks ( Rock Creek, Cabin John Creek, and Watts Branch), Rockville provided an excellent refuge for semi-nomadic Native Americans as early as 8000 BC. By the first millennium BC, a few of these groups had settled down into year-round agricultural communities that exploited the native flora, includi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Seattle Children's
Seattle Children's, formerly Children's Hospital and Regional Medical Center, formerly Children's Orthopedic Hospital, is a children's hospital in the Laurelhurst neighborhood of Seattle, Washington. The hospital specializes in the care of infants, children, teens, and young adults aged 0–21 in several specialties. History The hospital was founded as the seven-bed Children's Orthopedic Hospital in 1907 by Anna Herr Clise after her 5-year-old son, Willis, died of inflammatory rheumatism in 1898. It was originally a ward of the downtown Seattle General Hospital. It moved to a cottage on Queen Anne Hill the next year, and in 1911 influential community members including Herbert Gowen and Mark A. Matthews dedicated a full 40-bed hospital at the same location. The library at the hospital was founded in 1946. In 1953, Children's moved to a new campus in Laurelhurst, east of the University of Washington. A research division, Seattle Children's Research Institute (SCRI), was es ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The virus previously had a provisional name, 2019 novel coronavirus (2019-nCoV), and has also been called the human coronavirus 2019 (HCoV-19 or hCoV-19). First identified in the city of Wuhan, Hubei, China, the World Health Organization declared the outbreak a public health emergency of international concern on January 30, 2020, and a pandemic on March 11, 2020. SARS‑CoV‑2 is a positive-sense single-stranded RNA virus that is contagious in humans. SARS‑CoV‑2 is a virus of the species ''severe acute respiratory syndrome–related coronavirus'' (SARSr-CoV), related to the SARS-CoV-1 virus that caused the 2002–2004 SARS outbreak. Despite its close relation to SARS-CoV-1, its closest known relatives, with which it forms a sister group, are the derived SARS ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Financial Times
The ''Financial Times'' (''FT'') is a British daily newspaper printed in broadsheet and published digitally that focuses on business and economic current affairs. Based in London, England, the paper is owned by a Japanese holding company, Nikkei, with core editorial offices across Britain, the United States and continental Europe. In July 2015, Pearson sold the publication to Nikkei for £844 million (US$1.32 billion) after owning it since 1957. In 2019, it reported one million paying subscriptions, three-quarters of which were digital subscriptions. The newspaper has a prominent focus on financial journalism and economic analysis over generalist reporting, drawing both criticism and acclaim. The daily sponsors an annual book award and publishes a " Person of the Year" feature. The paper was founded in January 1888 as the ''London Financial Guide'' before rebranding a month later as the ''Financial Times''. It was first circulated around metropolitan London by James Sherid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tanzania Commission For Science And Technology
The Tanzania Commission for Science and Technology (COSTECH) is a parastatal organization affiliated with the government of Tanzania. It was created by an Act of the National Assembly of Tanzania in 1986 as a successor to the Tanzania National Scientific Research Council. The commission was a subsidiary institution to the Ministry of Communications, Science and Technology (MCST) and is now a subsidiary institution to the Ministry of Education, Science & Technology. The main offices are located in Dar es Salaam. COSTECH is currently led by Dr. Amos Nungu, who formerly served as Assistant Director of Science, Technology and Innovation at the Ministry of Education, Science and Technology]. Function The function of COSTECH is that of "co-ordinating and promoting research and technology development activities in the country." COSTECH is the "chief advisor to the Government on all matters pertaining to science and technology and their application to the socio-economic development of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Federal Council (Switzerland)
The Federal Council (german: Bundesrat; french: Conseil fédéral; it, Consiglio federale; rm, Cussegl federal) is the executive body of the federal government of the Swiss Confederation and serves as the collective head of state and government of Switzerland. It meets in the west wing of the Federal Palace in Bern. While the entire Federal Council is responsible for leading the federal administration of Switzerland, each Councillor heads one of the seven federal executive departments. The position of President of the Swiss Confederation rotates among the seven Councillors on a yearly basis, with one year's Vice President of Switzerland becoming the next year's President of Switzerland. Ignazio Cassis has been the incumbent officeholder since 1 January 2022. An election of the entire Federal Council occurs every four years; voting is restricted to the 246 members of the Federal Assembly of Switzerland. There is no mechanism for recall after election. Incumbents are almost a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Swiss Tropical And Public Health Institute
The Swiss Tropical and Public Health Institute or Swiss TPH (formerly known as the Swiss Tropical Institute) is an international public health institute working in various disciplines with a particular focus on low- and middle-income countries. It was founded in 1943 through the initiative of Rudolf Geigy. Swiss TPH endeavors to the improve the health of populations internationally and nationally through research, services, education, and training, with a focus on developing countries. In June 2009, the Institute for Social and Preventive Medicine of the University of Basel was integrated into the Swiss Tropical Institute, and in January 2010 the Swiss Tropical Institute changed its name to the Swiss Tropical and Public Health Institute. The Swiss TPH is an associated institute of the University of Basel, and as a public organization it is partially supported by the Swiss Federal Council and the Canton of Basel-Stadt. The greater part of its funding comes from competitively acqu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Tübingen
The University of Tübingen, officially the Eberhard Karl University of Tübingen (german: Eberhard Karls Universität Tübingen; la, Universitas Eberhardina Carolina), is a public research university located in the city of Tübingen, Baden-Württemberg, Germany. The University of Tübingen is one of eleven German Excellence Universities. The University of Tübingen is especially known as a centre for the study of plant biology, medicine, law, archeology, ancient cultures, philosophy, theology, and religious studies as well as more recently as center of excellence for artificial intelligence. The university's noted alumni include presidents, EU Commissioners, and judges of the Federal Constitutional Court. The university is associated with eleven Nobel laureates, especially in the fields of medicine and chemistry. History The University of Tübingen was founded in 1477 by Count Eberhard V (Eberhard im Bart, 1445–1496), later the first Duke of Württemberg, a civic and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leiden University
Leiden University (abbreviated as ''LEI''; nl, Universiteit Leiden) is a Public university, public research university in Leiden, Netherlands. The university was founded as a Protestant university in 1575 by William the Silent, William, Prince of Orange, as a reward to the city of Leiden for its Siege of Leiden, defence against Spanish attacks during the Eighty Years' War. As the oldest institution of higher education in the Netherlands, it enjoys a reputation across Europe and the world. Known for its historic foundations and emphasis on the social sciences, the university came into particular prominence during the Dutch Golden Age, when scholars from around Europe were attracted to the Dutch Republic due to its climate of intellectual tolerance and Leiden's international reputation. During this time, Leiden became the home to individuals such as René Descartes, Rembrandt, Christiaan Huygens, Hugo Grotius, Baruch Spinoza and Baron d'Holbach. The university has seven academic f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Radboud University Nijmegen
Radboud University (abbreviated as RU, nl, Radboud Universiteit , formerly ''Katholieke Universiteit Nijmegen'') is a public research university located in Nijmegen, the Netherlands. The university bears the name of Saint Radboud, a 9th century Dutch bishop who was known for his intellect and support of the underprivileged. Established in 1923, Radboud University has consistently been included in the top 150 of universities in the world by four major university ranking tables. As of 2020, it ranks 105th in the Shanghai Academic Ranking of World Universities. Internationally, RU is known for its strong research output. In 2020, 391 PhD degrees were awarded, and 8.396 scientific articles were published. To bolster the international exchange of academic knowledge, Radboud University joined the Guild of European Research-Intensive Universities in 2016. Among its alumni Radboud University counts 12 Spinoza Prize laureates and 1 Nobel Prize laureate, Sir Konstantin Novoselov, the disco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Noble Energy
Noble Energy, Inc. was a company engaged in hydrocarbon exploration headquartered in Houston, Texas. In October 2020, the company was acquired by Chevron Corporation. The company was known as Noble Affiliates, Inc. until 2002. As of December 31, 2018, the company had of proved reserves, of which 52% was in the United States, 43% was in Israel, and 5% was in Equatorial Guinea. Of the company's total proved reserves as of December 31, 2018, 62% was natural gas, 14% was natural gas liquids, and 24% was petroleum. In the United States, the company's primary holdings were in the Wattenberg Gas Field / Denver Basin in Colorado, the Delaware Basin, and the Eagle Ford Group. As of December 31, 2018, the company owned approximately 74,000 net developed acres and 111,000 net undeveloped acres between 10 and 90 miles offshore Israel in water depths ranging from 700 feet to 6,500 feet. Noble holds a 39.66% working interest in the Leviathan gas field, which it discovered in 2010 and a 25 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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