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Samin Sharma
Samin K. Sharma (born May 28, 1955) is an American philanthropist of Indian descent and an interventional cardiologist who co-founded the Eternal Heart Care Centre and Research Institute in Jaipur (EHCC). Sharma has served on New York State’s Cardiac Advisory Board since 2004. As of 2021, he is Senior Vice-President, Operations & Quality at The Mount Sinai Hospital in New York and runs the ''Dr. Samin K. Sharma Family Foundation Cardiac Catheterization Laboratory''. As of 2018, he is Chairman Board of Trustees, Association of Indians in America (AIA). As of 2022, he has been an investigator on 86 grants and multi-center trials and authored 486 peer-reviewed articles that have been cited 21,734 times. Biography Education Sharma was born to a Brahmin family in Alwar, India. He graduated from Rajgarh Higher Secondary School in Alwar. In 1972, he received his bachelor of science degree from University Maharaja College then his MBBS degree from SMS Medical Department of Pharma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alwar
Alwar (Pronunciation: Help:IPA/Hindi and Urdu, [əlʋəɾ]) is a city located in India's National Capital Region (India), National Capital Region and the administrative headquarters of Alwar district, Alwar District in the state of Rajasthan. It is located 150 km south of Delhi and 150 km north of Jaipur. At present the district is famous for production of Mustard Crop in the region, manufacturing of Ray-Ban, Ray Ban eyeglasses, Beer production plants and frozen food industry. Etymology There are many theories about the derivation of the name Alwar. Alexander Cunningham, Cunningham holds that the city derived its name from the Salva tribe and was originally Salwapur, then Salwar, Halawar and eventually Alwar, According to another school it was known as Aravalpur or the city of Aravalli Range, Aravali. Some others hold that city is named after Khanzada Alawal Khan, Alaval Khan Mewati (Khanzadas of Mewat, Khanzada prince who wrested Alwar from Nikumbh Rajputs). A rese ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aortic Stenosis
Aortic stenosis (AS or AoS) is the narrowing of the exit of the left ventricle of the heart (where the aorta begins), such that problems result. It may occur at the aortic valve as well as above and below this level. It typically gets worse over time. Symptoms often come on gradually with a decreased ability to exercise often occurring first. If heart failure, loss of consciousness, or heart related chest pain occur due to AS the outcomes are worse. Loss of consciousness typically occurs with standing or exercising. Signs of heart failure include shortness of breath especially when lying down, at night, or with exercise, and swelling of the legs. Thickening of the valve without narrowing is known as aortic sclerosis. Causes include being born with a bicuspid aortic valve, and rheumatic fever; a normal valve may also harden over the decades. A bicuspid aortic valve affects about one to two percent of the population. As of 2014 rheumatic heart disease mostly occurs in the dev ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rajiv Gandhi
Rajiv Gandhi (; 20 August 1944 – 21 May 1991) was an Indian politician who served as the sixth prime minister of India from 1984 to 1989. He took office after the 1984 assassination of his mother, then Prime Minister Indira Gandhi, to become the youngest Indian Prime minister at the age of 40. Gandhi was from the politically powerful Nehru–Gandhi family, which had been associated with the Indian National Congress party. For much of his childhood, his maternal grandfather Jawaharlal Nehru was prime minister. Gandhi attended college at the University of Cambridge in the United Kingdom. He returned to India in 1966 and became a professional pilot for the state-owned Indian Airlines. In 1968, he married Sonia Gandhi; the couple settled in Delhi to a domestic life with their children Rahul Gandhi and Priyanka Gandhi Vadra. For much of the 1970s, his mother Indira Gandhi was prime minister and his brother Sanjay Gandhi an MP; despite this, Rajiv Gandhi remained apolitical. Aft ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Republican Congressional Committee
The National Republican Congressional Committee (NRCC) is the Republican Hill committee which works to elect Republicans to the United States House of Representatives. The NRCC was formed in 1866, when the Republican caucuses of the House and Senate formed a "Congressional Committee". It supports the election of Republicans to the House through direct financial contributions to candidates and Republican Party organizations; technical and research assistance to Republican candidates and Party organizations; voter registration, education and turnout programs; and other Party-building activities. It is a registered 527 group. NRCC leadership The NRCC is always chaired by a Republican member of the House, who may serve up to two consecutive terms. It is governed by an Executive Committee of 11 members, which includes the party's Leader in the House ''ex officio'', and other members elected by the Republican Conference following a House election. The Chairman is elected by the H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Angina
Angina, also known as angina pectoris, is chest pain or pressure, usually caused by ischemia, insufficient blood flow to the Cardiac muscle, heart muscle (myocardium). It is most commonly a symptom of coronary artery disease. Angina is typically the result of vascular occlusion, obstruction or vasospasm, spasm of the coronary arteries, arteries that supply blood to the heart muscle. The main mechanism of coronary artery obstruction is atherosclerosis as part of coronary artery disease. Other causes of angina include cardiac arrhythmia, abnormal heart rhythms, heart failure and, less commonly, anemia. The term derives from the Latin ''angere'' ("to strangle") and ''pectus'' ("chest"), and can therefore be translated as "a strangling feeling in the chest". There is a weak relationship between severity of angina and degree of oxygen deprivation in the heart muscle, however, the severity of angina does not always match the degree of oxygen deprivation to the heart or the risk of a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aortic Valve
The aortic valve is a valve in the heart of humans and most other animals, located between the left ventricle and the aorta. It is one of the four valves of the heart and one of the two semilunar valves, the other being the pulmonary valve. The aortic valve normally has three cusps or leaflets, although in 1–2% of the population it is found to congenitally have two leaflets. The aortic valve is the last structure in the heart the blood travels through before stopping the flow through the systemic circulation. Structure The aortic valve normally has three cusps however there is some discrepancy in their naming. They may be called the left coronary, right coronary and non-coronary cusp. Some sources also advocate they be named as a left, right and posterior cusp. Anatomists have traditionally named them the left posterior (origin of left coronary), anterior (origin of the right coronary) and right posterior. The three cusps, when the valve is closed, contain a sinus called an a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transcatheter Arterial Chemoembolization
Transcatheter arterial chemoembolization (TACE) is a minimally invasive procedure performed in interventional radiology to restrict a tumor's blood supply. Small embolism, embolic particles coated with list of chemotherapeutic agents, chemotherapeutic drugs are injected selectively through a catheter into an artery directly supplying the tumor. These particles both block the blood supply and induce cytotoxicity, attacking the tumor in several ways. The radiotherapeutic analogue (combining radiotherapy with embolization) is called radioembolization or selective internal radiation therapy (SIRT). Principles TACE derives its beneficial effect by two primary mechanisms. Most tumors within the liver are supplied by the proper hepatic artery, so arterial embolization preferentially interrupts the tumor's blood supply and stalls growth until neovascularization. Secondly, focused administration of chemotherapy allows for delivery of a higher dose to the tissue while simultaneously reducing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Percutaneous Coronary Intervention
Percutaneous coronary intervention (PCI) is a non-surgical procedure used to treat narrowing of the coronary arteries of the heart found in coronary artery disease. The process involves combining coronary angioplasty with stenting, which is the insertion of a permanent wire-meshed tube that is either drug eluting (DES) or composed of bare metal (BMS). The stent delivery balloon from the angioplasty catheter is inflated with media to force contact between the struts of the stent and the vessel wall (stent apposition), thus widening the blood vessel diameter. After accessing the blood stream through the femoral or radial artery, the procedure uses coronary catheterization to visualise the blood vessels on X-ray imaging. After this, an interventional cardiologist can perform a coronary angioplasty, using a balloon catheter in which a deflated balloon is advanced into the obstructed artery and inflated to relieve the narrowing; certain devices such as stents can be deployed to keep ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Percutaneous Aortic Valve Replacement
Percutaneous aortic valve replacement (PAVR), also known as percutaneous aortic valve implantation (PAVI), transcatheter aortic valve implantation (TAVI) or transcatheter aortic valve replacement (TAVR), is the replacement of the aortic valve of the heart through the blood vessels (as opposed to valve replacement by open heart surgery, surgical aortic valve replacement, SAVR). The replacement valve is delivered via one of several access methods: transfemoral (in the upper leg), transapical (through the wall of the heart), subclavian (beneath the collar bone), direct aortic (through a minimally invasive surgical incision into the aorta), and transcaval (from a temporary hole in the aorta near the navel through a vein in the upper leg), among others. Severe symptomatic aortic stenosis carries a poor prognosis. At present there is no treatment via medication, making the timing of aortic valve replacement the most important decision to make for these patients. Until recently, surgi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Multicenter Trial
A multicenter research trial is a clinical trial conducted at more than one medical center or clinic. Most large clinical trials, particularly Clinical trial#Phase III, Phase III trials, are conducted at several clinical research centers. Benefits The benefits of multicenter trials include a larger number of participants, different geographic locations, the possibility of inclusion of a wider range of population groups, and the ability to compare results among centers, all of which increase the generalizability of the study. In many cases, efficacy will vary significantly between population groups with different genetic, environmental, and ethnic or cultural backgrounds ("demographic" factors); normally only geographically dispersed trials can properly evaluate this. External links ClinicalTrials.govfrom US National Library of MedicineRole of ICH GCP and Recruitment Strategies Training of Clinical Sites Staff in Successful Patient Recruitment Rates By Marithea Goberville, Ph.D.< ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Manmohan Singh
Manmohan Singh (; born 26 September 1932) is an Indian politician, economist and statesman who served as the 13th prime minister of India from 2004 to 2014. He is also the third longest-serving prime minister after Jawaharlal Nehru and Indira Gandhi. A member of the Indian National Congress, Singh was the first Sikh prime minister of India. He was also the first prime minister since Jawaharlal Nehru to be re-elected after completing a full five-year term. Born in Gah, Pakistan, Gah, Punjab (region), West Punjab, in what is today Pakistan, Singh's family migrated to India during Partition of India, its partition in 1947. After obtaining his doctorate in economics from Nuffield College, Oxford, Oxford, Singh worked for the United Nations during 1966–1969. He subsequently began his bureaucratic career when Lalit Narayan Mishra hired him as an advisor in the Ministry of Commerce and Industry (India), Ministry of Commerce and Industry. During the 1970s and 1980s, Singh held seve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Angiography
Angiography or arteriography is a medical imaging technique used to visualize the inside, or lumen, of blood vessels and organs of the body, with particular interest in the arteries, veins, and the heart chambers. Modern angiography is performed by injecting a radio-opaque contrast agent into the blood vessel and imaging using X-ray based techniques such as fluoroscopy. The word itself comes from the Greek words ἀγγεῖον ''angeion'' 'vessel' and γράφειν ''graphein'' 'to write, record'. The film or image of the blood vessels is called an ''angiograph'', or more commonly an ''angiogram''. Though the word can describe both an arteriogram and a venogram, in everyday usage the terms angiogram and arteriogram are often used synonymously, whereas the term venogram is used more precisely. The term angiography has been applied to radionuclide angiography and newer vascular imaging techniques such as CO2 angiography, CT angiography and MR angiography. The term ''isotope a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
