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SCGB2A2
Mammaglobin-A also known as secretoglobin family 2A member 2 is a protein that in humans is encoded by the ''SCGB2A2'' gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba .... Function SCGB2A2 is a member of the superfamily of secretoglobins, a group of small dimeric secreted and sometimes glycosylated proteins. Expressed mainly in mucosa, secretoglobins seem to be involved in cell signalling, immune response, and chemotaxis, and may also serve as transporters for steroid hormones in humans. Clinical significance SCGB2A2 expression is highly specific of mammary tissue, and is increasingly used for identification and detection of disseminated breast cancer cells. References Further reading * * * * * * * * * * * * * * Human proteins {{gene-11-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Breast Cancer Research And Treatment
''Breast Cancer Research and Treatment'' is a scientific journal focused on the treatment of and investigations in breast cancer. It is targeted towards a wide audience of clinical researchers, epidemiologists, immunologists, or cell biologists interested in breast cancer. The types of articles in this journal include original research, invited reviews, discussions on controversial issues, book reviews, meeting reports, letters to the editors, and editorials. Manuscripts are peer reviewed by an international and multidisciplinary panel of advisory editors. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 4.872. References {{Reflist Oncology journals Breast cancer Publications establishe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endocrine-Related Cancer
''Endocrine-Related Cancer'' is a monthly peer-reviewed medical journal covering cancers in endocrine organs — such as the breast, prostate, pituitary, testes, ovaries, and neuroendocrine system — and hormone-dependent cancers occurring elsewhere in the body. Its scope covers basic, translational, clinical and experimental studies. The journal is published by Bioscientifica on behalf of the Society for Endocrinology. It is also an official journal of the European Society of Endocrinology, the Endocrine Society of Australia and the Japanese Hormone and Cancer Society. The editor-in-chief is Matthew Ringel MD, PhD (Ralph W. Kurtz Professor of Medicine, and Director of the Division of Endocrinology and Metabolism at The Ohio State University, USA) and, according to the ISI Journal Citation Reports, the journal has a 2020 impact factor of 5.678. History ''Endocrine-Related Cancer'' was founded as ''Reviews on Endocrine-Related Cancer'', the in-house journal of Zeneca (n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioscientifica
Established in 1996, Bioscientifica Ltd is the commercial subsidiary of the Society for Endocrinology, and provides publishing, events, and association management services to biomedical societies, and to the pharmaceutical industry. Although the company generates profits, these are redistributed to Bioscientifica's partner societies to fund biomedical research and practice. Publishing Bioscientifica publishes academic journals and case reports focused on endocrinology, and its intersecting disciplines. The company also publishes free-to-read conference abstracts via its BiosciAbstracts platform and conference proceedings via Bioscientifica Proceedings. According to the 2016 ''Journal Citation Reports'', six of Bioscientifica's publications have an impact factor: ''Endocrine-Related Cancer'', ''Journal of Endocrinology'', ''Journal of Molecular Endocrinology'', '' European Journal of Endocrinology'', '' Reproduction (journal)'' and '' Endocrine Connections''. Bioscientifica was ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
