SBMA Official Logo (standard)
SBMA may refer to: * Santa Barbara Museum of Art * Spinal and bulbar muscular atrophy * Subic Bay Metropolitan Authority The Subic Bay Metropolitan Authority (abbreviated as "SBMA", fil, Pangasiwaang Panlungsod ng Subic Bay) is a governmental agency of the Philippines. Sometimes abbreviated as SBMA, the agency has played a significant part in the development of t ...

Spinal And Bulbar Muscular Atrophy
Spinal and bulbar muscular atrophy (SBMA), popularly known as Kennedy's disease, is a debilitating neurodegenerative disorder resulting in muscle cramps and progressive weakness due to degeneration of motor neurons in the brainstem and spinal cord and muscle wasting. The condition is associated with mutation of the androgen receptor (''AR'') gene and is inherited in an X-linked recessive manner. As with many genetic disorders, no cure is known, although research continues. Because of its endocrine manifestations related to the impairment of the ''AR'' gene, patients with SBMA develop partial symptoms of androgen insensitivity syndrome (AIS) in addition to neuromuscular degeneration. SBMA is related to other neurodegenerative diseases caused by similar mutations, such as Huntington's disease. The prevalence of SBMA has been estimated at 2.6:100,000 males. Signs and symptoms Individuals with SBMA have muscle cramps and progressive weakness due to degeneration of motor neurons in t ...
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