Rule Of Three (statistics)
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Rule Of Three (statistics)
In statistical analysis, the rule of three states that if a certain event did not occur in a sample with Design of experiments, subjects, the interval from 0 to 3/ is a 95% confidence interval for the rate of occurrences in the population (statistics), population. When is greater than 30, this is a good approximation of results from more sensitive tests. For example, a pain-relief drug is tested on 1500 Human subjects research, human subjects, and no adverse event is recorded. From the rule of three, it can be concluded with 95% confidence that fewer than 1 person in 500 (or 3/1500) will experience an adverse event. By symmetry, for only successes, the 95% confidence interval is . The rule is useful in the interpretation of clinical trials generally, particularly in Phases of clinical research#Phase II, phase II and phase III where often there are limitations in duration or statistical power. The rule of three applies well beyond medical research, to any trial done t ...
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Rule Of Three
Rule of three or Rule of Thirds may refer to: Science and technology *Rule of three (aeronautics), a rule of descent in aviation *Rule of three (C++ programming), a rule of thumb about class method definitions *Rule of three (computer programming), a rule of thumb about code refactoring *Rule of three (hematology), a rule of thumb to check if blood count results are correct *Rule of three (mathematics), a method in arithmetic *Rule of three (medicinal chemistry), a rule of thumb for lead-like compounds *Rule of three (statistics), for calculating a confidence limit when no events have been observed *Rule of threes (survival), the rule of threes involves the priorities in order to survive Arts and entertainment * ''Rule of Three'', a podcast by Jason Hazeley and Joel Morris#Podcast, Jason Hazeley and Joel Morris * ''Rule of Three'', a series of one-act plays Agatha Christie bibliography, by Agatha Christie * The Bellman's Rule of Three in ''The Hunting of the Snark'', a poem by Le ...
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