Royan Institute
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Royan Institute
Royan Institute ( fa, پژوهشگاه رویان) is an Iranian clinical, research and educational institute dedicated to biomedical, translational and clinical researches, stem cell research and infertility treatment. It is a public non-profitable organization affiliated to Academic Center for Education, Culture and Research. It was established in 1991 by the late Dr. Saeid Kazemi Ashtiani as a research institute for Reproductive Biomedicine and infertility treatments. In 1998 this institute was approved by Ministry of Health as Cell Based Research Center with over 46 scientific members and 186 lab technicians. Research institutes Royan consists of three research institutes, each focused on different fields of research: * Royan Institute for Stem Cell Biology and Technology (RI-SCB* Royan Institute for Reproductive Biomedicine (RI-RB) * Royan Institute for Animal Biotechnology (RI-AB) The institute has had close collaborations with other leading Iranian research centers as In ...
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Research Institute
A research institute, research centre, research center or research organization, is an establishment founded for doing research. Research institutes may specialize in basic research or may be oriented to applied research. Although the term often implies natural science research, there are also many research institutes in the social science as well, especially for sociological and historical research purposes. Famous research institutes In the early medieval period, several astronomical observatories were built in the Islamic world. The first of these was the 9th-century Baghdad observatory built during the time of the Abbasid caliph al-Ma'mun, though the most famous were the 13th-century Maragheh observatory, and the 15th-century Ulugh Beg Observatory. The Kerala School of Astronomy and Mathematics was a school of mathematics and astronomy founded by Madhava of Sangamagrama in Kerala, India. The school flourished between the 14th and 16th centuries and the original discoverie ...
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Beta Cell
Beta cells (β-cells) are a type of cell found in pancreatic islets that synthesize and secrete insulin and amylin. Beta cells make up 50–70% of the cells in human islets. In patients with Type 1 diabetes, beta-cell mass and function are diminished, leading to insufficient insulin secretion and hyperglycemia. Function The primary function of a beta cell is to produce and release insulin and amylin. Both are hormones which reduce blood glucose levels by different mechanisms. Beta cells can respond quickly to spikes in blood glucose concentrations by secreting some of their stored insulin and amylin while simultaneously producing more. Primary cilia on beta cells regulate their function and energy metabolism. Cilia deletion can lead to islet dysfunction and type 2 diabetes. Insulin synthesis Beta cells are the only site of insulin synthesis in mammals. As glucose stimulates insulin secretion, it simultaneously increases proinsulin biosynthesis, mainly through translational cont ...
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Health Care In Iran
''For health issues in Iran see Health in Iran.'' Healthcare in Iran is based on three pillars: the public-governmental system, the private sector, and NGOs. The healthcare and medical sector's market value in Iran was almost US$24 billion in 2002 and is forecast to rise to US$96 billion in 2017. With a population of 80 million (2017), Iran is one of the most populous countries in West Asia. The country faces the common problem of other young demographic nations in the region, which is keeping pace with growth of an already huge demand for various public services. The young population will soon be old enough to start new families, which will boost the population growth rate and subsequently the need for public health infrastructures and services. Total healthcare spending is expected to rise from $24.3 billion in 2008, to $96 billion by 2017, reflecting the increasing demand on medical services. Total health spending was equivalent to 6% of GDP in Iran in 2017. About 90% of Iranian ...
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California Institute For Regenerative Medicine
The California Institute for Regenerative Medicine (CIRM) was created in 2004 after 59% of California voters approved California Proposition 71: the Research and Cures Initiative, which allocated $3 billion to fund stem cell research in California. Institutes dedicated to stem cell research and training exist at Sanford Consortium, University of California, Santa Cruz, Stanford University, University of California Davis, University of California Irvine, University of California San Francisco, University of California Los Angeles and University of Southern California. Five “Alpha Stem Cell Clinics have also been established to lead clinical trials for stem cell therapies at City of Hope, University of California San Diego, University of California San Francisco, University of California Davis and a joint clinic at University of California Los Angeles and University of California Irvine. History CIRM was established via California Proposition 71 (2004). However, its implementation ...
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Avicenna Research Institute
Avicenna Research Institute (ARI; fa, پژوهشگاه ابن سینا) ) – affiliated to ACECR – was established in Tehran in order to achieve the latest medical technologies through conducting clinical and laboratory research projects in 1998. The institute consists of three research centers, including the Reproductive Biotechnology Research Center (RBRC), the Monoclonal Antibody Research Center (MARC), and the Nanobiotechnology Research Center (NBRC). ARI also includes the Avicenna Biotechnology Incubator and the Avicenna Infertility Clinic (AIC). Named after Ibn Sina, the research institute was founded in 1998 at Shahid Beheshti University in Tehran. The Reproductive Biotechnology Research Center (RBRC) includes Embryology and Andrology, Reproductive Genetics and Biotechnology, Reproductive Immunology, Reproductive Infections, and Bio Law & Ethics departments. For the purpose of laying the groundwork to provide therapeutic services and applied research findings in the ...
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Mouflon
The mouflon (''Ovis gmelini'') is a wild sheep native to Cyprus, the Caspian Sea, Caspian region from eastern Turkey, Armenia, Azerbaijan, and Iran. It is thought to be the ancestor of all modern domestic sheep breeds. Taxonomy ''Ovis gmelini'' was the scientific name proposed by Edward Blyth in 1841 for wild sheep in the Middle East. In the 19th and 20th centuries, several wild sheep were described that are considered mouflon subspecies today: * ''Ovis ophion'' by Blyth in 1841 for wild sheep in Cyprus; * ''Ovis laristanica'' by Nikolai Nasonov in 1909 for wild sheep in Lar, Iran, Lar in southern Iran; * ''Ovis orientalis isphahanica'' by Nasonov in 1910 for wild sheep in the Zagros Mountains. Subspecies Five mouflon subspecies of are distinguished by Mammal Species of the World, MSW3: * Armenian mouflon (Armenian red sheep), ''O. g. gmelini'' : nominate subspecies; native to northwestern Iran, Armenia, and Azerbaijan. It has been introduced to Texas in the U.S. * Esfahan mou ...
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Royana (cloned Sheep)
Royana (2006–2010) was Iran's and the Middle East's first successfully cloned sheep. Royana was a brown male domestic sheep and was cloned in the Royan Research Institute in Isfahan, Iran (The word ''Royan'' means ''embryo'' in Persian). He was the second cloned sheep in Royan Research Institute, but whereas the first sheep died few hours after birth, Royana lived for a few years. Birth On September 30, 2006, a group of scientists in Iran cloned Royana from an adult cell in a test tube in a laboratory. After the embryo proved its stability, scientists transferred it to the uterus of a female sheep. After a period of 145 days, Royana was born by caesarean section. Despite critical conditions, he survived and thrived. Royana was born on April 15, 2006, 1:30 am at Isfahan campus of Royan Institute by cesarean section in a healthy condition. Death Royana was euthanized after the abdominal pain was traced to his liver. It was also thought that Royana suffered premature death synd ...
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Neuron
A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. Non-animals like plants and fungi do not have nerve cells. Neurons are typically classified into three types based on their function. Sensory neurons respond to stimuli such as touch, sound, or light that affect the cells of the sensory organs, and they send signals to the spinal cord or brain. Motor neurons receive signals from the brain and spinal cord to control everything from muscle contractions to glandular output. Interneurons connect neurons to other neurons within the same region of the brain or spinal cord. When multiple neurons are connected together, they form what is called a neural circuit. A typical neuron consists of a cell body (soma), dendrites, and a single axon. The soma is a compact structure, and the axon and dend ...
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Cardiac Muscle
Cardiac muscle (also called heart muscle, myocardium, cardiomyocytes and cardiac myocytes) is one of three types of vertebrate muscle tissues, with the other two being skeletal muscle and smooth muscle. It is an involuntary, striated muscle that constitutes the main tissue of the wall of the heart. The cardiac muscle (myocardium) forms a thick middle layer between the outer layer of the heart wall (the pericardium) and the inner layer (the endocardium), with blood supplied via the coronary circulation. It is composed of individual cardiac muscle cells joined by intercalated discs, and encased by collagen fibers and other substances that form the extracellular matrix. Cardiac muscle contracts in a similar manner to skeletal muscle, although with some important differences. Electrical stimulation in the form of a cardiac action potential triggers the release of calcium from the cell's internal calcium store, the sarcoplasmic reticulum. The rise in calcium causes the ...
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Tehran
Tehran (; fa, تهران ) is the largest city in Tehran Province and the capital of Iran. With a population of around 9 million in the city and around 16 million in the larger metropolitan area of Greater Tehran, Tehran is the most populous city in Iran and Western Asia, and has the second-largest metropolitan area in the Middle East, after Cairo. It is ranked 24th in the world by metropolitan area population. In the Classical era, part of the territory of present-day Tehran was occupied by Rhages, a prominent Median city destroyed in the medieval Arab, Turkic, and Mongol invasions. Modern Ray is an urban area absorbed into the metropolitan area of Greater Tehran. Tehran was first chosen as the capital of Iran by Agha Mohammad Khan of the Qajar dynasty in 1786, because of its proximity to Iran's territories in the Caucasus, then separated from Iran in the Russo-Iranian Wars, to avoid the vying factions of the previously ruling Iranian dynasties. The capital has been ...
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Embryonic Stem Cell
Embryonic stem cells (ESCs) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre- implantation embryo. Human embryos reach the blastocyst stage 4–5 days post fertilization, at which time they consist of 50–150 cells. Isolating the inner cell mass (embryoblast) using immunosurgery results in destruction of the blastocyst, a process which raises ethical issues, including whether or not embryos at the pre-implantation stage have the same moral considerations as embryos in the post-implantation stage of development. Researchers are currently focusing heavily on the therapeutic potential of embryonic stem cells, with clinical use being the goal for many laboratories. Potential uses include the treatment of diabetes and heart disease. The cells are being studied to be used as clinical therapies, models of genetic disorders, and cellular/DNA repair. However, adverse effects in the research and clinical processes such as tumors and unw ...
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Impact Factor
The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as indexed by Clarivate's Web of Science. As a journal-level metric, it is frequently used as a proxy for the relative importance of a journal within its field; journals with higher impact factor values are given the status of being more important, or carry more prestige in their respective fields, than those with lower values. While frequently used by universities and funding bodies to decide on promotion and research proposals, it has come under attack for distorting good scientific practices. History The impact factor was devised by Eugene Garfield, the founder of the Institute for Scientific Information (ISI) in Philadelphia. Impact factors began to be calculated yearly starting from 1975 for journals listed in the ''Journal Citation Rep ...
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