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Rosin (chemical)
Rosin is a glycoside ester of Cinnamyl alcohol and a constituent of ''Rhodiola rosea''. Related compounds The three cinnamyl alcohol-vicianosides of rhodiola rosea commonly referred to as "rosavins" are rosin and the structurally related disaccharide Rosavin which is the arabinose ester of rosin, and Rosarin, the arabinofuranose ester of rosin. Salidroside Salidroside (rhodioloside) is a glucoside of tyrosol found in the plant ''Rhodiola rosea''. It has been studied, along with rosavin, as one of the potential compounds responsible for the putative antidepressant and anxiolytic actions of this pla ..., common in rhodiola spp. and occurring in Rhodiola rosea is not a cinnamyl alcohol glycoside, but a glycoside of tyrosol.http://jultika.oulu.fi/files/isbn9514280806.pdf Sources The cinnamyl alcohol glycosides rosin, rosavin and rosarin occur in the context of rhodiola species, only in Rhodiola rosea. References Crassulaceae Neuroprotective agents Phenylpropanoid glycoside ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cinnamyl Alcohol
Cinnamyl alcohol or styron is an organic compound that is found in esterified form in storax, Balsam of Peru, and cinnamon leaves. It forms a white crystalline solid when pure, or a yellow oil when even slightly impure. It can be produced by the hydrolysis of storax. Cinnamyl alcohol has a distinctive odour described as "sweet, balsam, hyacinth, spicy, green, powdery, cinnamic" and is used in perfumery and as a deodorant. Cinnamyl alcohol is naturally occurrent only in small amount, so its industrial demand is usually fulfilled by chemical synthesis starting from cinnamaldehyde. Properties The compound is a solid at room temperature, forming colourless crystals that melt upon gentle heating. As is typical of most higher-molecular weight alcohols, it is sparingly soluble in water at room temperature, but highly soluble in most common organic solvents. Safety Cinnamyl alcohol has been found to have a sensitising effect on some people [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rhodiola Rosea
''Rhodiola rosea'' (commonly golden root, rose root, roseroot, Aaron's rod, Arctic root, king's crown, ''lignum rhodium'', orpin rose) is a perennial flowering plant in the family Crassulaceae. It grows naturally in wild Arctic regions of Europe (including Britain), Asia, and North America ( N.B., Nfld. and Labrador, N.S., QC.; Alaska, Maine, N.Y., N.C., Pa., Vt), and can be propagated as a groundcover. Although ''Rhodiola rosea'' has been used in traditional medicine, there is no high-quality clinical evidence of its effectiveness to treat any disease. The United States Food and Drug Administration has issued several warnings to manufacturers of ''R. rosea'' dietary supplements for making false health claims about its safety and efficacy. The plant is threatened in many countries due to rapidly growing demand. Supply comes mostly from wild harvesting on an industrial scale, and a combination of growing scarcity and a lack of regulation has led to environmental degradation, su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rosavin
Rosavin (also known as rosin, rosavin, and rosarin) are a family of cinnamyl mono- and diglycosides that are key ingredients of ''Rhodiola rosea'' L., (''R. rosea''). ''R. rosea'' is an important medicinal plant commonly used throughout Europe, Asia, and North America, that has been recognized as a botanical adaptogen by the European Medicines Agency. Rosavin production is specific to ''R. rosea'' and ''R. sachalinenis'', and the biosynthesis of these glycosides occurs spontaneously in ''Rhodiola'' roots and rhizomes. The production of rosavins increases in plants as they get older, and the amount of the cinnamyl alcohol glycosides depends on the place of origin of the plant. Biosynthesis Cinnamyl alcohol glycosides are products of phenylpropanoid metabolism, derived from phenylalanine, which is produced from the shikimic-chorismic acid pathway. Shikimic acid is made from the precursor compounds erythrose-4-phosphate, and phosphoenolpyruvate. Shikimic acid is then converted to c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rosarin
Rosarin is a cinnamyl alcohol glycoside isolated from ''Rhodiola rosea ''Rhodiola rosea'' (commonly golden root, rose root, roseroot, Aaron's rod, Arctic root, king's crown, ''lignum rhodium'', orpin rose) is a perennial flowering plant in the family Crassulaceae. It grows naturally in wild Arctic regions of Europe ...''. References External links Purification of Phenylalkanoids and monoterpene glycosides from Rhodiola rosea L. roots by high-speed counter-current chromatography Phenylpropanoid glycosides {{organic-chem-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Salidroside
Salidroside (rhodioloside) is a glucoside of tyrosol found in the plant ''Rhodiola rosea''. It has been studied, along with rosavin, as one of the potential compounds responsible for the putative antidepressant and anxiolytic actions of this plant. Salidroside may be more active than rosavin, even though many commercially marketed ''Rhodiola rosea'' extracts are standardized for rosavin content rather than salidroside. Bioactivities Salidroside was shown to improve glucose homeostasis and alleviate diabetic retinopathy in obese mice. The antioxidant, anti-inflammatory and neuroprotective effects of salidroside have also been reported. Biosynthesis The salidroside biosynthetic pathway in ''Rhodiola rosea'' was described in 2018. Rhodiola contains a pyridoxal phosphate-dependent 4-hydroxyphenylacetaldehyde (4-HPAA) synthase that converts tyrosine to 4-HPAA, which is further reduced to tyrosol Tyrosol is an organic compound with the formula . Classified as a phenylethanoid, i.e. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Crassulaceae
The Crassulaceae (from Latin ''crassus'', thick), also known as the stonecrop family or the orpine family, are a diverse family of dicotyledon flowering plants characterized by succulent leaves and a unique form of photosynthesis, known as Crassulacean acid metabolism (CAM). Flowers generally have five floral parts. Crassulaceae are usually herbaceous but there are some subshrubs, and relatively few treelike or aquatic plants. Crassulaceae are a medium size monophyletic family in the core eudicots, among the order Saxifragales, whose diversity has made infrafamilial classification very difficult. The family includes approximately 1,400 species and 34–35 genera, depending on the circumscription of the genus ''Sedum'', and distributed over three subfamilies. Members of the Crassulaceae are found worldwide, but mostly in the Northern Hemisphere and southern Africa, typically in dry and/or cold areas where water may be scarce, although a few are aquatic. Crassulaceae are mainly pe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroprotective Agents
Neuroprotection refers to the relative preservation of neuronal structure and/or function. In the case of an ongoing insult (a neurodegenerative insult) the relative preservation of neuronal integrity implies a reduction in the rate of neuronal loss over time, which can be expressed as a differential equation. It is a widely explored treatment option for many central nervous system (CNS) disorders including neurodegenerative diseases, stroke, traumatic brain injury, spinal cord injury, and acute management of neurotoxin consumption (i.e. methamphetamine overdoses). Neuroprotection aims to prevent or slow disease progression and secondary injuries by halting or at least slowing the loss of neurons. Despite differences in symptoms or injuries associated with CNS disorders, many of the mechanisms behind neurodegeneration are the same. Common mechanisms of neuronal injury include decreased delivery of oxygen and glucose to the brain, energy failure, increased levels in oxidative stre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
