Ron Appel
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Ron Appel
Ron David Appel (born 13 April 1959) is a Swiss bioinformatician, professor of proteomics and bioinformatics at the University of Geneva and executive director of the Swiss Institute of Bioinformatics. Education Ron Appel graduated in Computer Sciences at the University of Geneva, where he also received his Ph.D in 1987, followed by a postdoctoral fellowship at Harvard School of Public Health. Career He was co-founder in 1998 of the SIB Swiss Institute of Bioinformatics, where he led the Proteome Informatics Group (PIG). The group developed proteomics software and databases, in particular the Melanie 2-D gel electrophoresis analysis software and the SWISS-2DPAGE database, as well as tools for the identification and characterisation of proteins using mass spectrometry. Ron Appel is also the initiator of and co-responsible for ExPASy, the world's first Web site dedicated to protein molecular biology, which has now become SIB’s main resource portal. It provides access to ...
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Ron Appel, Current Director Of The Swiss Institute Of Bioinformatics, 2013
Ron is a shortening of the name Ronald. Ron or RON may also refer to: Arts and media * Big Ron (''EastEnders''), a TV character * Ron (''King of Fighters''), a video game character *Ron Douglas, the protagonist in ''Lucky Stiff'' played by Joe Alasky * Ron Weasley, a character in ''Harry Potter.'' Language * Ron language, spoken in Plat State, Nigeria * Romanian language (ISO 639-3 code ron) People Mononym *Ron (singer), Rosalino Cellamare (born 1953), Italian singer Given name * Ron (given name) Surname *Dana Ron (born 1964), Israeli computer scientist and professor *Elaine Ron (1943-2010), American epidemiologist *Emri Ron (born 1936), Israeli politician *Ivo Ron (born 1967), Ecuadorian football player *Jason De Ron (born 1973), Australian musician *José Ron (born 1981), Mexican actor *Liat Ron, actress, dancer and dance instructor * *Lior Ron (born 1982), Israeli-American film and trailer composer and musician *Michael Ron (born 1932), Israeli fencer *Michael Røn (born ...
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Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Ro ...
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1959 Births
Events January * January 1 - Cuba: Fulgencio Batista flees Havana when the forces of Fidel Castro advance. * January 2 - Lunar probe Luna 1 was the first man-made object to attain escape velocity from Earth. It reached the vicinity of Earth's Moon, and was also the first spacecraft to be placed in heliocentric orbit. * January 3 ** The three southernmost atolls of the Maldive archipelago ( Addu Atoll, Huvadhu Atoll and Fuvahmulah island) declare independence. ** Alaska is admitted as the 49th U.S. state. * January 4 ** In Cuba, rebel troops led by Che Guevara and Camilo Cienfuegos enter the city of Havana. ** Léopoldville riots: At least 49 people are killed during clashes between the police and participants of a meeting of the ABAKO Party in Léopoldville in the Belgian Congo. * January 6 ** Fidel Castro arrives in Havana. ** The International Maritime Organization is inaugurated. * January 7 – The United States recognizes the new Cuban government of F ...
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Health On The Net Foundation
Health On the Net Foundation (HON) is a Geneva, Switzerland-based not-for-profit organization which promotes a code of conduct for websites providing health information and offers certificates to those in compliance. In September 2022, Health On the Net website pages included the advisory text "HON is no longer updated and will be permanently discontinued on December 15, 2022. Despite all our efforts, it is no longer possible to maintain it. We thank you for your understanding." Foundation In 1995, 60 participants at an international health conference agreed to form a permanent body to promote the dissemination of accurate health information through technology. Health On the Net was founded under the auspices of the Geneva Department of Employment, Social Affairs and Health. It holds consultative status with the Economic and Social Council of the United Nations (ECOSOC) and a special relationship with the World Health Organization (WHO). The French National Health Authority app ...
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Population Genetics
Population genetics is a subfield of genetics that deals with genetic differences within and between populations, and is a part of evolutionary biology. Studies in this branch of biology examine such phenomena as adaptation, speciation, and population structure. Population genetics was a vital ingredient in the emergence of the modern evolutionary synthesis. Its primary founders were Sewall Wright, J. B. S. Haldane and Ronald Fisher, who also laid the foundations for the related discipline of quantitative genetics. Traditionally a highly mathematical discipline, modern population genetics encompasses theoretical, laboratory, and field work. Population genetic models are used both for statistical inference from DNA sequence data and for proof/disproof of concept. What sets population genetics apart from newer, more phenotypic approaches to modelling evolution, such as evolutionary game theory and adaptive dynamics, is its emphasis on such genetic phenomena as dominance, epi ...
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Systems Biology
Systems biology is the computational modeling, computational and mathematical analysis and modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach (holism instead of the more traditional reductionist, reductionism) to biological research. Particularly from the year 2000 onwards, the concept has been used widely in biology in a variety of contexts. The Human Genome Project is an example of applied systems thinking in biology which has led to new, collaborative ways of working on problems in the biological field of genetics. One of the aims of systems biology is to model and discover emergent property, emergent properties, properties of cell (biology), cells, tissue (biology), tissues and organisms functioning as a system whose theoretical description is only possible using techniques of systems biology. These typically involve metabolic networks or cell ...
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Phylogeny
A phylogenetic tree (also phylogeny or evolutionary tree Felsenstein J. (2004). ''Inferring Phylogenies'' Sinauer Associates: Sunderland, MA.) is a branching diagram or a tree showing the evolutionary relationships among various biological species or other entities based upon similarities and differences in their physical or genetic characteristics. All life on Earth is part of a single phylogenetic tree, indicating common ancestry. In a ''rooted'' phylogenetic tree, each node with descendants represents the inferred most recent common ancestor of those descendants, and the edge lengths in some trees may be interpreted as time estimates. Each node is called a taxonomic unit. Internal nodes are generally called hypothetical taxonomic units, as they cannot be directly observed. Trees are useful in fields of biology such as bioinformatics, systematics, and phylogenetics. ''Unrooted'' trees illustrate only the relatedness of the leaf nodes and do not require the ancestral root to be ...
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Transcriptomics
Transcriptomics technologies are the techniques used to study an organism's transcriptome, the sum of all of its RNA transcripts. The information content of an organism is recorded in the DNA of its genome and expressed through transcription. Here, mRNA serves as a transient intermediary molecule in the information network, whilst non-coding RNAs perform additional diverse functions. A transcriptome captures a snapshot in time of the total transcripts present in a cell. Transcriptomics technologies provide a broad account of which cellular processes are active and which are dormant. A major challenge in molecular biology is to understand how a single genome gives rise to a variety of cells. Another is how gene expression is regulated. The first attempts to study whole transcriptomes began in the early 1990s. Subsequent technological advances since the late 1990s have repeatedly transformed the field and made transcriptomics a widespread discipline in biological sciences. There ar ...
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Genomics
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration. In contrast to genetics, which refers to the study of ''individual'' genes and their roles in inheritance, genomics aims at the collective characterization and quantification of ''all'' of an organism's genes, their interrelations and influence on the organism. Genes may direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes. Advances in ...
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Switzerland
). Swiss law does not designate a ''capital'' as such, but the federal parliament and government are installed in Bern, while other federal institutions, such as the federal courts, are in other cities (Bellinzona, Lausanne, Luzern, Neuchâtel, St. Gallen a.o.). , coordinates = , largest_city = Zürich , official_languages = , englishmotto = "One for all, all for one" , religion_year = 2020 , religion_ref = , religion = , demonym = , german: Schweizer/Schweizerin, french: Suisse/Suissesse, it, svizzero/svizzera or , rm, Svizzer/Svizra , government_type = Federalism, Federal assembly-independent Directorial system, directorial republic with elements of a direct democracy , leader_title1 = Federal Council (Switzerland), Federal Council , leader_name1 = , leader_title2 = , leader_name2 = Walter Thurnherr , legislature = Fe ...
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