Rickettsialpox
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Rickettsialpox
Rickettsialpox is a mite-borne infectious illness caused by bacteria of the genus ''Rickettsia'' (''Rickettsia akari''). Physician Robert Huebner and self-trained entomologist Charles Pomerantz played major roles in identifying the cause of the disease after an outbreak in 1946 in a New York City apartment complex, documented in "The Alerting of Mr. Pomerantz," an article by medical writer Berton Roueché. Although it is not transmitted by a tick (a characteristic of spotted fever), the bacterium is a part of the spotted fever group of ''Rickettsia'', and so this condition is often classified with that group. Signs and symptoms The first symptom is a bump formed by the bite, eventually resulting in a black, crusty scab. Many of the symptoms are flu-like including fever, chills, weakness and achy muscles but the most distinctive symptom is the rash that breaks out, spanning the infected person's entire body. Transmission The bacteria are originally found in mice and cause mites ...
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Rickettsia Akari
''Rickettsia akari'' is a species of ''Rickettsia'' which causes rickettsialpox. After a 1946 outbreak of a rickettsial-type disease at an apartment complex in Kew Gardens, Queens, an investigation was performed to identify the source of the infections. The incinerators in the buildings were not operated on a daily basis, leading to a buildup in food waste and attracting mice that were rampant throughout the building. The ''Mus musculus'' mice were found to be carrying mites, identified as the house mouse mite, ''Allodermanyssus sanguineus''. Self-trained entomologist Charles Pomerantz asked permission to search the site and found the mites at various sites throughout the building, with blood-engorged mites found near chutes leading to the incinerator. The mites were collected and brought to a laboratory of the United States Public Health Service, which found in the mites an organism that had also been isolated from the mice, and from the blood of individuals infected with the dis ...
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Liponyssoides Sanguineus
''Liponyssoides sanguineus'' is a species of mite that infests the house mouse (''Mus musculus''). It can transmit human disease, is associated with causing rodent mite dermatitis in humans and is noted for carrying ''Rickettsia akari'', which causes rickettsialpox. It was formerly known as ''Allodermanyssus sanguineus''. See also * List of mites associated with cutaneous reactions Many mites can bite human skin and cause cutaneous reaction and/or disease. Mites which cannot bite humans may also transmit disease or cause allergies. See also * List of conditions associated with café au lait macules *List of contact all ... References Mesostigmata Cosmopolitan arthropods {{acari-stub ...
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Rickettsioses
A rickettsiosis is a disease caused by intracellular bacteria. Cause Rickettsioses can be divided into a spotted fever group (SPG) and typhus group (TG). In the past, rickettsioses were considered to be caused by species of Rickettsia. However, scrub typhus is still considered a rickettsiosis, even though the causative organism has been reclassified from ''Rickettsia tsutsugamushi'' to ''Orientia tsutsugamushi''.Examples of rickettsioses include typhus, both endemic and epidemic, Rocky Mountain spotted fever, and Rickettsialpox. Organisms involved include Rickettsia parkeri. Many new causative organisms have been identified in the last few decades. Most are in the genus ''Rickettsia'', but scrub typhus is in the genus ''Orientia''. Diagnosis No rapid laboratory tests are available to diagnose rickettsial diseases early in the course of illness, and serologic assays usually take 10–12 days to become positive. Research is indicating that swabs of eschars may be used for molecular ...
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Rickettsia
''Rickettsia'' is a genus of nonmotile, gram-negative, nonspore-forming, highly pleomorphic bacteria that may occur in the forms of cocci (0.1 μm in diameter), bacilli (1–4 μm long), or threads (up to about 10 μm long). The term "rickettsia" has nothing to do with rickets (which is a deficiency disease resulting from lack of vitamin D); the bacterial genus ''Rickettsia'' instead was named after Howard Taylor Ricketts, in honor of his pioneering work on tick-borne spotted fever. Properly, ''Rickettsia'' is the name of a single genus, but the informal term "rickettsia", plural "rickettsias", usually not capitalised, commonly applies to any members of the order Rickettsiales. Being obligate intracellular bacteria, rickettsias depend on entry, growth, and replication within the cytoplasm of living eukaryotic host cells (typically endothelial cells). Accordingly, ''Rickettsia'' species cannot grow in artificial nutrient culture; they must be grown either in tissue or embryo ...
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House Mouse
The house mouse (''Mus musculus'') is a small mammal of the order Rodentia, characteristically having a pointed snout, large rounded ears, and a long and almost hairless tail. It is one of the most abundant species of the genus '' Mus''. Although a wild animal, the house mouse has benefited significantly from associating with human habitation to the point that truly wild populations are significantly less common than the semi-tame populations near human activity. The house mouse has been domesticated as the pet or fancy mouse, and as the laboratory mouse, which is one of the most important model organisms in biology and medicine. The complete mouse reference genome was sequenced in 2002. Characteristics House mice have an adult body length (nose to base of tail) of and a tail length of . The weight is typically . In the wild they vary in color from grey and light brown to black (individual hairs are actually agouti coloured), but domesticated fancy mice and laboratory mice ar ...
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Robert Huebner
Robert Joseph Huebner (February 23, 1914 – August 26, 1998), was an American physician and virologist whose research into viruses, their causes and treatment that led to his breakthrough insights into the connections between viruses and cancer, leading to new treatments, as well as his hypothesized oncogene, which was discovered to be a trigger for normal cells turning cancerous. Early life and education Huebner was born in Cheviot, Ohio, a western suburb of Cincinnati, on February 23, 1914. After attending a local parish elementary school, he attended Elder High School, graduating in 1932.Beeman, Edward A"Robert J. Huebner, M.D.:A Virologist’s Odyssey" National Institutes of Health'', 2005. Accessed July 23, 2009. He attended Xavier College (later Xavier University, where he majored in economics and English literature and took the prerequisites to attend law school. He decided he wanted to become a physician and did his premed undergraduate training at the University of ...
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List Of Mites Associated With Cutaneous Reactions
Many mites can bite human skin and cause cutaneous reaction and/or disease. Mites which cannot bite humans may also transmit disease or cause allergies. See also * List of conditions associated with café au lait macules *List of contact allergens *List of cutaneous conditions associated with increased risk of nonmelanoma skin cancer *List of cutaneous conditions associated with internal malignancy *List of cutaneous conditions caused by mutations in keratins *List of cutaneous neoplasms associated with systemic syndromes *List of cutaneous conditions caused by problems with junctional proteins *List of dental abnormalities associated with cutaneous conditions *List of genes mutated in cutaneous conditions *List of genes mutated in pigmented cutaneous lesions *List of histologic stains that aid in diagnosis of cutaneous conditions *List of human leukocyte antigen alleles associated with cutaneous conditions *List of immunofluorescence findings for autoimmune bullous conditions ...
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House (TV Series)
''House'' (also called ''House, M.D.'') is an American medical drama television series that originally ran on the Fox network for eight seasons, from November 16, 2004, to May 21, 2012. The series' main character is Dr. Gregory House (Hugh Laurie), an unconventional, misanthropic medical genius who, despite his dependence on pain medication, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital (PPTH) in New Jersey. The series' premise originated with Paul Attanasio, while David Shore, who is credited as creator, was primarily responsible for the conception of the title character. The series' executive producers included Shore, Attanasio, Attanasio's business partner Katie Jacobs, and film director Bryan Singer. It was filmed largely in a neighborhood and business district in Los Angeles County's Westside called Century City. The show received high critical acclaim, and was consistently one of the highest rated series in the United States. ...
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The Bronx
The Bronx () is a borough of New York City, coextensive with Bronx County, in the state of New York. It is south of Westchester County; north and east of the New York City borough of Manhattan, across the Harlem River; and north of the New York City borough of Queens, across the East River. The Bronx has a land area of and a population of 1,472,654 in the 2020 census. If each borough were ranked as a city, the Bronx would rank as the ninth-most-populous in the U.S. Of the five boroughs, it has the fourth-largest area, fourth-highest population, and third-highest population density.New York State Department of Health''Population, Land Area, and Population Density by County, New York State – 2010'' retrieved on August 8, 2015. It is the only borough of New York City not primarily on an island. With a population that is 54.8% Hispanic as of 2020, it is the only majority-Hispanic county in the Northeastern United States and the fourth-most-populous nationwide. The Bronx ...
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The New York Times
''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid digital subscribers. It also is a producer of popular podcasts such as '' The Daily''. Founded in 1851 by Henry Jarvis Raymond and George Jones, it was initially published by Raymond, Jones & Company. The ''Times'' has won 132 Pulitzer Prizes, the most of any newspaper, and has long been regarded as a national " newspaper of record". For print it is ranked 18th in the world by circulation and 3rd in the U.S. The paper is owned by the New York Times Company, which is publicly traded. It has been governed by the Sulzberger family since 1896, through a dual-class share structure after its shares became publicly traded. A. G. Sulzberger, the paper's publisher and the company's chairman, is the fifth generation of the family to head the pa ...
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Chickenpox
Chickenpox, also known as varicella, is a highly contagious disease caused by the initial infection with varicella zoster virus (VZV). The disease results in a characteristic skin rash that forms small, itchy blisters, which eventually scab over. It usually starts on the chest, back, and face. It then spreads to the rest of the body. The rash and other symptoms, such as fever, tiredness, and headaches, usually last five to seven days. Complications may occasionally include pneumonia, inflammation of the brain, and bacterial skin infections. The disease is usually more severe in adults than in children. Chickenpox is an airborne disease which spreads easily from one person to the next through the coughs and sneezes of an infected person. The incubation period is 10–21 days, after which the characteristic rash appears. It may be spread from one to two days before the rash appears until all lesions have crusted over. It may also spread through contact with the blisters. Tho ...
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National Institutes Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research instit ...
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