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Ray K Iles
Ray Kruse Iles is a biomedical scientist who was head of the Williamson Laboratory for Molecular Oncology at St Bartholomew's Hospital in London. Career Iles has a particular interest in the interface between rational processing, emotional motivation and endocrinology. He co-founded the ELK-Health Foundation, with psychotherapist Tadhg Ó Séaghdha, in 2004. The ELK-Foundation Health (named after Iles's father, Eric Leonard Kruse) is now the National Institutes for Stress, Anxiety and Depression (NISAD), centred in Lund, Sweden. It still uses the ELK-Health name in its programmes and clinics, which support people needing to change habits that harm their physical and emotional health. Iles's interest in women's and reproduction health led him, in 2011, to become the founding director of the biomarker diagnostic company MAPSciences. Iles is the inventor of new diagnostic technology, six clinical screening tests for pregnancy disorders and Downs Syndrome/prenatal diagnosis, hae ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cropped Lab Ray Iles
Cropping is the removal of unwanted outer areas from a photographic or illustrated image. The process usually consists of the removal of some of the peripheral areas of an image to remove extraneous trash from the picture, to improve its framing, to change the aspect ratio, or to accentuate or isolate the subject matter from its background. Depending on the application, this can be performed on a physical photograph, artwork, or film footage, or it can be achieved digitally by using image editing software. The process of cropping is common to the photographic, film processing, broadcasting, graphic design, and printing businesses. In photography, print, and design In the printing, graphic design and photography industries, cropping is the removal of unwanted areas from the periphery of a photographic or illustrated image. Cropping is one of the most basic photo manipulation processes, and it is carried out to remove an unwanted object or irrelevant noise from the peripher ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
St Bartholomew's Hospital
St Bartholomew's Hospital, commonly known as Barts, is a teaching hospital located in the City of London. It was founded in 1123 and is currently run by Barts Health NHS Trust. History Early history Barts was founded in 1123 by Rahere (died 1144, and entombed in the nearby Priory Church of St Bartholomew the Great), a favourite courtier of King Henry I. The dissolution of the monasteries did not affect the running of Barts as a hospital, but left it in a precarious position by removing its income. It was refounded by King Henry VIII in December 1546, on the signing of an agreement granting the hospital to the Corporation of London.''St Bartholomew's Hospital'' ''Old and New London'': Volume 2 (1878), pp. 359–363. Retrieved 30 January 2009 The hospital became legally styled as the "House of the Poore ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Down Syndrome
Down syndrome or Down's syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. It is usually associated with physical growth delays, mild to moderate intellectual disability, and characteristic facial features. The average IQ of a young adult with Down syndrome is 50, equivalent to the mental ability of an eight- or nine-year-old child, but this can vary widely. The parents of the affected individual are usually genetically normal. The probability increases from less than 0.1% in 20-year-old mothers to 3% in those of age 45. The extra chromosome is believed to occur by chance, with no known behavioral activity or environmental factor that changes the probability. Down syndrome can be identified during pregnancy by prenatal screening followed by diagnostic testing or after birth by direct observation and genetic testing. Since the introduction of screening, Down syndrome pregnancies are often abor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prenatal Diagnosis
Prenatal testing consists of prenatal screening and prenatal diagnosis, which are aspects of prenatal care that focus on detecting problems with the pregnancy as early as possible. These may be anatomic and physiologic problems with the health of the zygote, embryo, or fetus, either before gestation even starts (as in preimplantation genetic diagnosis) or as early in gestation as practicable. Screening can detect problems such as neural tube defects, chromosome abnormalities, and gene mutations that would lead to genetic disorders and birth defects, such as spina bifida, cleft palate, Down syndrome, Tay–Sachs disease, sickle cell anemia, thalassemia, cystic fibrosis, muscular dystrophy, and fragile X syndrome. Some tests are designed to discover problems which primarily affect the health of the mother, such as PAPP-A to detect pre-eclampsia or glucose tolerance tests to diagnose gestational diabetes. Screening can also detect anatomical defects such as hydrocephalus, anencephal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haemoglobinopathies
Hemoglobinopathy is the medical term for a group of inherited blood disorders and diseases that primarily affect red blood cells. They are single-gene disorders and, in most cases, they are inherited as autosomal co-dominant traits. There are two main groups: abnormal structural hemoglobin variants caused by mutations in the hemoglobin genes, and the thalassemias, which are caused by an underproduction of otherwise normal hemoglobin molecules. The main structural hemoglobin variants are HbS, HbE and HbC. The main types of thalassemia are alpha-thalassemia and beta thalassemia. The two conditions may overlap because some conditions which cause abnormalities in hemoglobin proteins also affect their production. Some hemoglobin variants do not cause pathology or anemia, and thus are often not classed as hemoglobinopathies. Hemoglobin structural biology Normal human hemoglobins are tetrameric proteins composed of two pairs of globin chains, each of which contains one alpha-like ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thalassemia
Thalassemias are inherited blood disorders characterized by decreased hemoglobin production. Symptoms depend on the type and can vary from none to severe. Often there is mild to severe anemia (low red blood cells or hemoglobin). Anemia can result in feeling tired and pale skin. There may also be bone problems, an enlarged spleen, yellowish skin, and dark urine. Slow growth may occur in children. Thalassemias are genetic disorders inherited from a person's parents. There are two main types, alpha thalassemia and beta thalassemia. The severity of alpha and beta thalassemia depends on how many of the four genes for alpha globin or two genes for beta globin are missing. Diagnosis is typically by blood tests including a complete blood count, special hemoglobin tests, and genetic tests. Diagnosis may occur before birth through prenatal testing. Treatment depends on the type and severity. Treatment for those with more severe disease often includes regular blood transfusions, iron chel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diabetes Mellitus
Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased appetite. If left untreated, diabetes can cause many health complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death. Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, damage to the nerves, damage to the eyes, and cognitive impairment. Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body not responding properly to the insulin produced. Insulin is a hormone which is responsible for helping glucose from food get into cells to be used for energy. There are three main types of diabetes mellitus: * Type 1 diabetes results from failure of the pancreas to produce enough insulin due to lo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mellow Lane School
Mellow Lane School was a comprehensive school, located in Hayes, in the London Borough of Hillingdon, Middlesex. It closed in 2011 and reopened in August of that year, as Hewens College. History The school was opened in 1938. It housed two departments, run as separate entities: the Mellow Lane Senior Boys' School and the Mellow Lane Senior Girls' School. In 1948, Mellow Lane was established as a co-educational comprehensive school. It was then one of only two experimental comprehensives in the UK permitted by the UK Government. It was a grant-maintained school between 1 April 1992 and 31 August 1999, and became a foundation secondary comprehensive school on 1 September 1999. The architects of the building were Curtis and Burchett. The building was extended in 1949 and 1963. Houses There were four houses during much of the school's existence: ''Dower'', which was red; ''Manor'', which was blue; ''Park'', which was green; and ''Round'', which was yellow. These were named afte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Richard Kruse
Richard Kruse (born 30 July 1983) is a former British right-handed foil fencer and four-time Olympian. In 2015, he was part of the Great Britain team that shocked Olympic champions Italy to win the first European Games gold in team foil, the first British gold medal in a team fencing event at World or European level for fifty years. He retired in 2021. Career Kruse won his first international medal, a silver, at the 2001 European Under 20 Championships and in 2002 won gold in at the same event. He made his Olympic debut at the 2004 Games in Athens, Greece. Competing in the men's individual foil. He received a bye in the first round, beat China's Wang Haibin in round two and Dan Kellner of the United States in the third round before being defeated 8–15 by Andrea Cassarà in the quarter-finals. His eighth-place finish was the best by a British fencer since the 1992 Summer Olympics in Barcelona, when Fiona McIntosh was eighth in the women's foil, and the best by a British man ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British Scientists
Science and technology in the United Kingdom has a long history, producing many important figures and developments in the field. Major theorists from the United Kingdom of Great Britain and Northern Ireland include Isaac Newton whose laws of motion and illumination of gravity have been seen as a keystone of modern science and Charles Darwin whose theory of evolution by natural selection was fundamental to the development of modern biology. Major scientific discoveries include hydrogen by Henry Cavendish, penicillin by Alexander Fleming, and the structure of DNA, by Francis Crick and others. Major engineering projects and applications pursued by people from the United Kingdom include the steam locomotive developed by Richard Trevithick and Andrew Vivian, the jet engine by Frank Whittle and the World Wide Web by Tim Berners-Lee. The United Kingdom continues to play a major role in the development of science and technology and major technological sectors include the aerospace, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British Medical Researchers
British may refer to: Peoples, culture, and language * British people, nationals or natives of the United Kingdom, British Overseas Territories, and Crown Dependencies. ** Britishness, the British identity and common culture * British English, the English language as spoken and written in the United Kingdom or, more broadly, throughout the British Isles * Celtic Britons, an ancient ethno-linguistic group * Brittonic languages, a branch of the Insular Celtic language family (formerly called British) ** Common Brittonic, an ancient language Other uses *''Brit(ish)'', a 2018 memoir by Afua Hirsch *People or things associated with: ** Great Britain, an island ** United Kingdom, a sovereign state ** Kingdom of Great Britain (1707–1800) ** United Kingdom of Great Britain and Ireland (1801–1922) See also * Terminology of the British Isles * Alternative names for the British * English (other) * Britannic (other) * British Isles * Brit (other) * Briton (d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
