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Radioimmunoassay
A radioimmunoassay (RIA) is an immunoassay that uses radiolabeled molecules in a stepwise formation of immune complexes. A RIA is a very sensitive in vitro assay technique used to measure concentrations of substances, usually measuring antigen concentrations (for example, hormone levels in blood) by use of antibodies. Although the RIA technique is extremely sensitive and extremely specific, requiring specialized equipment, it remains among the least expensive methods to perform such measurements. It requires special precautions and licensing, since radioactive substances are used. In contrast, an immunoradiometric assay (IRMA) is an immunoassay that uses radiolabeled molecules but in an immediate rather than stepwise way. A radioallergosorbent test (RAST) is an example of radioimmunoassay. It is used to detect the causative allergen for an allergy. Method Classically, to perform a radioimmunoassay, a known quantity of an antigen is made radioactive, frequently by labeling it wi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rosalyn Sussman Yalow
Rosalyn Sussman Yalow (July 19, 1921 – May 30, 2011) was an American medical physicist, and a co-winner of the 1977 Nobel Prize in Physiology or Medicine (together with Roger Guillemin and Andrew Schally) for development of the radioimmunoassay technique. She was the second woman (after Gerty Cori), and the first American-born woman, to be awarded the Nobel Prize in Physiology or Medicine. Biography Childhood Rosalyn Sussman Yalow was born in the Bronx, New York, the daughter of Clara (née Zipper) and Simon Sussman, and was raised in a Jewish household. She went to Walton High School (Bronx), New York City. After high school, she attended the all-female, tuition-free Hunter College, where her mother hoped she would learn to become a teacher. Instead, Yalow decided to study physics. College Yalow knew how to type, and was able to get a part-time position as a secretary to Dr. Rudolf Schoenheimer, a leading biochemist at Columbia University's College of Physicians and Surgeons. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
