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Rütger Wever
Rütger Wever was a German scientist, known for his significant contributions to the field of Chronobiology, including some of the first experiments on humans in time isolated environments. Time isolation experiments Rütger Wever's research focused on the human circadian rhythm, and how humans behave when placed in an environment where they have no external time cues and are free to choose their own sleep/wake and light/dark schedules. Working with his close collaborator Jürgen Aschoff, he had an underground bunker constructed in Andechs, Germany, for use as a laboratory in which human subjects could be shielded from any external time cues, including variations in light, temperature, and electromagnetic fields. Between 1964 and 1989, this bunker was used to conduct 418 studies in 447 human volunteers. One of the key findings of these experiments was that when free to self-select their schedules, humans run on an approximately 25-h day. More recent experiments have shown that th ...
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Germany
Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated between the Baltic and North seas to the north, and the Alps to the south; it covers an area of , with a population of almost 84 million within its 16 constituent states. Germany borders Denmark to the north, Poland and the Czech Republic to the east, Austria and Switzerland to the south, and France, Luxembourg, Belgium, and the Netherlands to the west. The nation's capital and most populous city is Berlin and its financial centre is Frankfurt; the largest urban area is the Ruhr. Various Germanic tribes have inhabited the northern parts of modern Germany since classical antiquity. A region named Germania was documented before AD 100. In 962, the Kingdom of Germany formed the bulk of the Holy Roman Empire. During the 16th ce ...
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Chronobiology
Chronobiology is a field of biology that examines timing processes, including periodic (cyclic) phenomena in living organisms, such as their adaptation to solar- and lunar-related rhythms. These cycles are known as biological rhythms. Chronobiology comes from the ancient Greek χρόνος (''chrónos'', meaning "time"), and biology, which pertains to the study, or science, of life. The related terms ''chronomics'' and ''chronome'' have been used in some cases to describe either the molecular mechanisms involved in chronobiological phenomena or the more quantitative aspects of chronobiology, particularly where comparison of cycles between organisms is required. Chronobiological studies include but are not limited to comparative anatomy, physiology, genetics, molecular biology and behavior of organisms related to their biological rhythms. Other aspects include epigenetics, development, reproduction, ecology and evolution. The subject Chronobiology studies variations of the ...
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Max Planck Institute For Behavioral Physiology
The former Max Planck Institute for Behavioral Physiology was located in Bulldern, Westphalia, Germany, moved to Seewiesen in 1957. It was one of 80 institutes in the Max Planck Society (Max Planck Gesellschaft). Background A working group was founded in 1954 by Erich von Holst ( Max Planck Institute for Oceanic biology, Wilhelmshaven) and Konrad Lorenz. In 1958 it moved into new buildings in Seewiesen. After working from 1951 to 1965, Irenaeus Eibl-Eibesfeldt became director of the institute in 1975. It became an independent institute 1987. In 1997 the Max Planck Society was required to cut its budget and four institutes, including the Behavioral Physiology unit, were chosen for closure, reportedly because their directors were nearing retirement and not due to any failures in scientific research."Max Planck to shutter institutes?" Kaiser, Jocelyn. ''Science''. Washington: Oct 25, 1996. Vol. 274, Iss. 5287; pg. 487, 1 pgs A part of it survived as the Max Planck Institute for Orn ...
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Circadian Rhythm
A circadian rhythm (), or circadian cycle, is a natural, internal process that regulates the sleep–wake cycle and repeats roughly every 24 hours. It can refer to any process that originates within an organism (i.e., Endogeny (biology), endogenous) and responds to the environment (Entrainment (chronobiology), entrained by the environment). These 24-hour rhythms are driven by a circadian clock, and they have been widely observed in animals, plants, fungi and cyanobacteria. The term ''circadian'' comes from the Latin ''wikt:circa#Latin, circa'', meaning "approximately", and ''dies'', meaning "day". Processes with 24-hour cycles are more generally called diurnal rhythms; diurnal rhythms should not be called circadian rhythms unless they can be confirmed as endogenous, and not environmental. Although circadian rhythms are endogenous, they are adjusted to the local environment by external cues called zeitgebers (German for "time givers"), which include light, temperature and redox cy ...
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Jürgen Aschoff
Jürgen Walther Ludwig Aschoff (January 25, 1913 – October 12, 1998) was a German physician, biologist and behavioral physiologist. Together with Erwin Bünning and Colin Pittendrigh, he is considered to be a co-founder of the field of chronobiology. Aschoff's work in the field of chronobiology introduced the idea that shifting one's light-dark cycle can result in harmful effects, such as correlations with mental illness. Life Aschoff was born in Freiburg Im Breisgau as the fifth child of the pathologist Ludwig Aschoff (known for discovering the Aschoff-Tawara or atrioventricular node) and his wife Clara. He grew up in the liberal but morally strict world of Prussian academia. After the Abitur at a humanistic high school, he – according to his own statement "lacking a specific interest" – studied medicine at the University of Bonn, where he joined the Burschenschaft (fraternity) Alemannia Bonn. Aschoff’s scientific career began in 1938, when he moved to the University of G ...
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Andechs
Andechs is a municipality in the district of Starnberg in Bavaria in Germany. It is renowned in Germany and beyond for Andechs Abbey, a Benedictine monastery that has brewed beer since 1455. The monastery brewery offers tours to visitors. The 20th-century German composer Carl Orff is buried in the chapel of Andechs Abbey. This town was the capital of one of the States of the Counts of Andechs The House of Andechs was a feudal line of German princes in the 12th and 13th centuries. The counts of Dießen-Andechs (1100 to 1180) obtained territories in northern Dalmatia on the Adriatic seacoast, where they became Margraves of Istria and ul ..., one of the most important families in Europe. References External links * * Starnberg (district) {{Starnberg-geo-stub ...
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Phase Response Curve
A phase response curve (PRC) illustrates the transient change (phase response) in the cycle period of an oscillation induced by a perturbation as a function of the phase at which it is received. PRCs are used in various fields; examples of biological oscillations are the heartbeat, circadian rhythms, and the regular, repetitive firing observed in some neurons in the absence of noise. In circadian rhythms In humans and animals, there is a regulatory system that governs the phase relationship of an organism's internal circadian clock to a regular periodicity in the external environment (usually governed by the solar day). In most organisms, a stable phase relationship is desired, though in some cases the desired phase will vary by season, especially among mammals with seasonal mating habits. In circadian rhythm research, a PRC illustrates the relationship between a chronobiotic's time of administration (relative to the internal circadian clock) and the magnitude of the treatment' ...
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Bunker Experiment
The bunker experiment was a scientific experiment that began in 1966 to test whether humans, like other species, have an intrinsic circadian clock. It was started by Jürgen Aschoff and Rütger Wever of the Max Planck Institute for Behavioral Physiology and later taken over by Jürgen Zulley. Participants lived in a bunker for multiple weeks while scientists measured their daily rhythms in many variables. The main conclusion of the experiment was that humans have an intrinsic clock with a period greater than 24 hours. The experiment also established many features of this clock and paved the way for future circadian studies. Background Before this experiment, scientists had already discovered that many plant and animal species have intrinsic clocks that can operate independently of external time cues. It is now known that these clocks operate based on molecular oscillations, using transcription-translation feedback loops and metabolic feedback loops. External cues, notably light ...
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Affective Disorders
The affective spectrum is a spectrum of affective disorders (mood disorders). It is a grouping of related psychiatric and medical disorders which may accompany bipolar, unipolar, and schizoaffective disorders at statistically higher rates than would normally be expected. These disorders are identified by a common positive response to the same types of pharmacologic treatments. They also aggregate strongly in families and may therefore share common heritable underlying physiologic anomalies. __TOC__ Types Affective spectrum disorders include: * Attention deficit hyperactivity disorder * Bipolar disorder * Body dysmorphic disorder * Bulimia nervosa and other eating disorders * Dysthymia * Generalized anxiety disorder * Impulse-control disorders * Kleptomania * Major depressive disorder * Obsessive-compulsive disorder * Oppositional defiant disorder * Panic disorder * Posttraumatic stress disorder * Premenstrual dysphoric disorder * Social anxiety disorder The following m ...
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Physics
Physics is the natural science that studies matter, its fundamental constituents, its motion and behavior through space and time, and the related entities of energy and force. "Physical science is that department of knowledge which relates to the order of nature, or, in other words, to the regular succession of events." Physics is one of the most fundamental scientific disciplines, with its main goal being to understand how the universe behaves. "Physics is one of the most fundamental of the sciences. Scientists of all disciplines use the ideas of physics, including chemists who study the structure of molecules, paleontologists who try to reconstruct how dinosaurs walked, and climatologists who study how human activities affect the atmosphere and oceans. Physics is also the foundation of all engineering and technology. No engineer could design a flat-screen TV, an interplanetary spacecraft, or even a better mousetrap without first understanding the basic laws of physic ...
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2010 Deaths
This is a list of deaths of notable people, organised by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked here. 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 See also * Lists of deaths by day The following pages, corresponding to the Gregorian calendar, list the historical events, births, deaths, and holidays and observances of the specified day of the year: Footnotes See also * Leap year * List of calendars * List of non-standard ... * Deaths by year {{DEFAULTSORT:deaths by year ...
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