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Ruth Chiquet-Ehrismann
Ruth Chiquet-Ehrismann (9 November 1954 – 4 September 2015) was a Swiss biochemist and cell biologist working on interactions in the extracellular matrix. Life Ruth Chiquet-Ehrismann was born in Zürich. She received her Ph.D. from the ETH Zürich in 1981. Her mentors were Hans M. Eppenberger and David C. Turner. As a postdoctoral fellow she worked with Robert Dottin at the Johns Hopkins University in Baltimore, US. In 1984 she joined the Friedrich Miescher Institute for Biomedical Research in Basel as a Junior group leader and was promoted to Senior group leader in 1993. In 2006 she was appointed as Adjunct Professor (Titularprofessorin) at the University of Basel. She was a board member of the Swiss Cancer League and the Cancer League of Basel, and chaired the Swiss Society for Connective Tissue Research. She served as a Council Member of the International Society for Matrix Biology. At the age of 60, she suffered a sudden death at her home in Pratteln, near Basel. C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zürich
Zürich () is the list of cities in Switzerland, largest city in Switzerland and the capital of the canton of Zürich. It is located in north-central Switzerland, at the northwestern tip of Lake Zürich. As of January 2020, the municipality has 434,335 inhabitants, the Urban agglomeration, urban area 1.315 million (2009), and the Zürich metropolitan area 1.83 million (2011). Zürich is a hub for railways, roads, and air traffic. Both Zurich Airport and Zürich Hauptbahnhof, Zürich's main railway station are the largest and busiest in the country. Permanently settled for over 2,000 years, Zürich was founded by the Roman Empire, Romans, who called it '. However, early settlements have been found dating back more than 6,400 years (although this only indicates human presence in the area and not the presence of a town that early). During the Middle Ages, Zürich gained the independent and privileged status of imperial immediacy and, in 1519, became a primary centre of the Protestant ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Matricellular Proteins
A matricellular protein is a dynamically expressed non-structural protein that is present in the extracellular matrix (ECM). Rather than serving as stable structural elements in the ECM, these proteins are rapidly turned over and have regulatory roles. They characteristically contain binding sites for ECM structural proteins and cell surface receptors, and may sequester and modulate activities of specific growth factors. Examples of matricellular proteins include the CCN family of proteins (also known as CCN intercellular signaling protein), fibulins, osteopontin, periostin, SPARC family members, tenascin(s), and thrombospondins. Many of these proteins have important functions in wound healing and tissue repair. See also * CCN protein CCN proteins are a family of extracellular matrix (ECM)-associated proteins involved in intercellular signaling. Due to their dynamic role within the ECM they are considered matricellular proteins. Background The acronym CCN is derived from the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2015 Deaths
This is a list of deaths of notable people, organised by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked here. 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 See also * Lists of deaths by day The following pages, corresponding to the Gregorian calendar, list the historical events, births, deaths, and holidays and observances of the specified day of the year: Footnotes See also * Leap year * List of calendars * List of non-standard ... * Deaths by year {{DEFAULTSORT:deaths by year ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ETH Zurich Alumni
(colloquially) , former_name = eidgenössische polytechnische Schule , image = ETHZ.JPG , image_size = , established = , type = Public , budget = CHF 1.896 billion (2021) , rector = Günther Dissertori , president = Joël Mesot , academic_staff = 6,612 (including doctoral students, excluding 527 professors of all ranks, 34% female, 65% foreign nationals) (full-time equivalents 2021) , administrative_staff = 3,106 (40% female, 19% foreign nationals, full-time equivalents 2021) , students = 24,534 (headcount 2021, 33.3% female, 37% foreign nationals) , undergrad = 10,642 , postgrad = 8,299 , doctoral = 4,460 , other = 1,133 , address = Rämistrasse 101CH-8092 ZürichSwitzerland , city = Zürich , coor = , campus = Urban , language = German, English (Masters and upwards, sometimes Bachelor) , affiliations = CESAER, EUA, GlobalTech, IARU, IDEA League, UNITECH , website ethz.ch, colors = Black and White , logo = ETH Zürich Logo black.svg ETH Züric ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Swiss Biochemists
Swiss may refer to: * the adjectival form of Switzerland *Swiss people Places *Swiss, Missouri * Swiss, North Carolina *Swiss, West Virginia *Swiss, Wisconsin Other uses *Swiss-system tournament, in various games and sports *Swiss International Air Lines **Swiss Global Air Lines, a subsidiary *Swissair, former national air line of Switzerland *.swiss alternative TLD for Switzerland See also *Swiss made, label for Swiss products *Swiss cheese (other) *Switzerland (other) *Languages of Switzerland, none of which are called "Swiss" *International Typographic Style, also known as Swiss Style, in graphic design *Schweizer (other), meaning Swiss in German *Schweitzer, a family name meaning Swiss in German *Swisse Swisse is a vitamin, supplement, and skincare brand. Founded in Australia in 1969 and globally headquartered in Melbourne, and was sold to Health & Happiness, a Chinese company based in Hong Kong previously known as Biostime International, in a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Teneurin
Teneurins are a family of phylogenetically conserved single-pass transmembrane glycoproteins expressed during pattern formation and morphogenesis. The name refers to "ten-a" (from " tenascin-like protein, accessory") and "neurons", the primary site of teneurin expression. Ten-m refers to tenascin-like protein major. Teneurins are highly conserved between ''Drosophila'', ''C. elegans'' and vertebrates. In each species, they are expressed by a subset of neurons as well as at sites of pattern formation and morphogenesis. In ''Drosophila'', a teneurin known as ten-m or Odz is a pair-rule gene, and its expression is required for normal development. The knockdown of teneurin (''ten-1'') expression in ''C. elegans'' with RNAi leads to abnormal neuronal pathfinding and abnormal development of the gonads. The intracellular domain of some, if not all, teneurins can be cleaved and transported to the cell nucleus, where it proposed to act as a transcription factor. A peptide derive ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MKL1
MKL/megakaryoblastic leukemia 1 (also termed MRTFA/myocardin related transcription factor A) is a protein that in humans is encoded by the ''MKL1'' gene. Function The protein encoded by this gene is regulated by the actin cytoskeleton and is shuttled between the cytoplasm and the nucleus as a result of actin dynamics. In the nucleus, it coactivates the transcription factor serum response factor, a key regulator of smooth muscle cell differentiation, in an interaction mediated by its Basic domain. It is closely related to MKL2 and myocardin, with which it shares five key conserved structural domains. Clinical significance This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. It also functions in the process of normal megakaryocyte maturation. Research Evalarted ''MKL1'' expression is observed in breast cancer and can p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tenascin C
Tenascin C (TN-C) is a glycoprotein that in humans is encoded by the ''TNC'' gene. It is expressed in the extracellular matrix of various tissues during development, disease or injury, and in restricted neurogenic areas of the central nervous system. Tenascin-C is the founding member of the tenascin protein family. In the embryo it is made by migrating cells like the neural crest; it is also abundant in developing tendons, bone and cartilage. Gene and expression The human tenascin C gene, ''TN-C'', is located on chromosome 9 with location of the cytogenic band at the 9q33. The entire Tenascin family coding region spans approximately 80 kilobases translating into 2203 amino acids. Expression of TN-C changes from development to adulthood. TN-C is highly expressed during embryogenesis and is briefly expressed during organogenesis, while in developed organs, expression is absent or in trace amounts. TN-C has been shown to be upregulated under pathological conditions caused by in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tenascin
Tenascins are extracellular matrix glycoproteins. They are abundant in the extracellular matrix of developing vertebrate embryos and they reappear around healing wounds and in the stroma of some tumors. Types There are four members of the tenascin gene family: tenascin-C, tenascin-R, tenascin-X and tenascin-W. * Tenascin-C is the founding member of the gene family. In the embryo it is made by migrating cells like the neural crest; it is also abundant in developing tendons, bone and cartilage. * Tenascin-R is found in the developing and adult nervous system. * Tenascin-X is found primarily in loose connective tissue; mutations in the human tenascin-X gene can lead to a form of Ehlers-Danlos syndrome. * Tenascin-W is found in the kidney and in developing bone. The basic structure is 14 EGF-like repeats towards the N-terminal end, and 8 or more fibronectin-III domains which vary upon species and variant. Tenascin-C is the most intensely studied member of the family. It has an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pratteln
Pratteln (Swiss German: ''Brattele'') is a Municipalities of Switzerland, municipality in the Cantons of Switzerland, canton of Basel-Landschaft in Switzerland, located in the district of Liestal (district), Liestal. History Pratteln is first mentioned around 1102-03 as ''Bratello''. Geography Pratteln has an area, , of . Of this area, or 27.6% is used for agricultural purposes, while or 28.1% is forested. Of the rest of the land, or 43.1% is settled (buildings or roads), or 0.9% is either rivers or lakes and or 0.4% is unproductive land.Swiss Federal Statistical Office-Land Use Statistics 2009 data accessed 25 March 2010 Of the built up area, industrial buildings made up 10.8% of the total area while housing and buildings made up 14.9% and tra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basel
, french: link=no, Bâlois(e), it, Basilese , neighboring_municipalities= Allschwil (BL), Hégenheim (FR-68), Binningen (BL), Birsfelden (BL), Bottmingen (BL), Huningue (FR-68), Münchenstein (BL), Muttenz (BL), Reinach (BL), Riehen (BS), Saint-Louis (FR-68), Weil am Rhein (DE-BW) , twintowns = Shanghai, Miami Beach , website = www.bs.ch Basel ( , ), also known as Basle ( ),french: Bâle ; it, Basilea ; rm, label= Sutsilvan, Basileia; other rm, Basilea . is a city in northwestern Switzerland on the river Rhine. Basel is Switzerland's third-most-populous city (after Zürich and Geneva) with about 175,000 inhabitants. The official language of Basel is (the Swiss variety of Standard) German, but the main spoken language is the local Basel German dialect. Basel is commonly considered to be the cultural capital of Switzerland and the city is famous for its many museums, including the Kunstmuseum, which is the first collection of art accessibl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
