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Ronald Breslow
Ronald Charles David Breslow (March 14, 1931 – October 25, 2017) was an American chemist from Rahway, New Jersey. He was University Professor at Columbia University, where he was based in the Department of Chemistry and affiliated with the Departments of Biological Sciences and Pharmacology; he had also been on the faculty of its Department of Chemical Engineering. He had taught at Columbia since 1956 and was a former chair of the university's chemistry department. Life and career Breslow was born in Rahway, New Jersey, the son of Gladys (Fellows) and Alexander E. Breslow. He was interested in the design and synthesis of new molecules with interesting properties, and the study of these properties. Examples include the cyclopropenyl cation, the simplest aromatic system and the first aromatic compound prepared with other than six electrons in a ring. His seminal contributions include the correct site of reactivity of thiamin diphosphate in enzymes that promote the decarboxy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rahway, New Jersey
Rahway () is a city in southern Union County, in the U.S. state of New Jersey. A bedroom community of New York City, it is centrally located in the Rahway Valley region, in the New York metropolitan area. The city is southwest of Manhattan and west of Staten Island. Built on the navigable Rahway River, it was an industrial and artisanal craft city for much of its history. The city has increasingly reinvented itself in recent years as a diverse regional hub for the arts. As of the 2010 United States Census, the city's population was 27,346,DP-1 - Profile of General Population and Housing Characteristics: 2010 Demographic Profile Data for Rahway city, Union County, New Jersey [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Perkin Medal
The Perkin Medal is an award given annually by the Society of Chemical Industry (American Section) to a scientist residing in America for an "innovation in applied chemistry resulting in outstanding commercial development." It is considered the highest honor given in the US chemical industry. The Perkin Medal was first awarded in 1906 to commemorate the 50th anniversary of the discovery of mauveine, the world's first synthetic aniline dye, by Sir William Henry Perkin, an English chemist. The award was given to Sir William on the occasion of his visit to the United States in the year before he died. It was next given in 1908 and has been given every year since then. Recipients See also * List of chemistry awards This list of chemistry awards is an index to articles about notable awards for chemistry. It includes awards by the Royal Society of Chemistry, the American Chemical Society, the Society of Chemical Industry and awards by other organizations. ... References { ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arthur C
Arthur is a common male given name of Brythonic origin. Its popularity derives from it being the name of the legendary hero King Arthur. The etymology is disputed. It may derive from the Celtic ''Artos'' meaning “Bear”. Another theory, more widely believed, is that the name is derived from the Roman clan '' Artorius'' who lived in Roman Britain for centuries. A common spelling variant used in many Slavic, Romance, and Germanic languages is Artur. In Spanish and Italian it is Arturo. Etymology The earliest datable attestation of the name Arthur is in the early 9th century Welsh-Latin text ''Historia Brittonum'', where it refers to a circa 5th to 6th-century Briton general who fought against the invading Saxons, and who later gave rise to the famous King Arthur of medieval legend and literature. A possible earlier mention of the same man is to be found in the epic Welsh poem ''Y Gododdin'' by Aneirin, which some scholars assign to the late 6th century, though this is still a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Welch Award
The Welch Award in Chemistry is awarded annually by the Robert A. Welch Foundation, based in Houston, Texas, to encourage and recognise basic chemical research for the benefit of mankind. The award, which has been given since 1972, is one of the largest and most prestigious awards in the field of chemistry. Several of its recipients subsequently were awarded the Nobel Prize. The award is named in honor of Robert Alonzo Welch, who made a fortune in oil and minerals and had a strong belief in the ability of chemistry to make the world a better place. In his will, Mr. Welch stated: “I have long been impressed with the great possibilities for the betterment of Mankind that lay in the field of research in the domain of Chemistry.” The prize has a value of $500,000. Recipients SourceWelch Foundation See also *List of chemistry awards *List of prizes named after people This is a list of awards that are named after people. A B C D E F G H I J K L ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vorinostat
Vorinostat (rINN) also known as Suberoylanilide hydroxamic acid ( suberoyl+anilide+hydroxamic acid abbreviated as SAHA) is a member of a larger class of compounds that inhibit histone deacetylases (HDAC). Histone deacetylase inhibitors (HDI) have a broad spectrum of epigenetic activities. Vorinostat is marketed under the name Zolinza ( ) by Merck for the treatment of cutaneous manifestations in patients with cutaneous T cell lymphoma (CTCL) when the disease persists, gets worse, or comes back during or after two systemic therapies. The compound was developed by Columbia University chemist Ronald Breslow and Memorial Sloan-Kettering researcher Paul Marks Medical uses Vorinostat was the first histone deacetylase inhibitor approved by the U.S. Food and Drug Administration (FDA) for the treatment of CTCL on October 6, 2006. It also failed to demonstrate efficacy in treating acute myeloid leukemia in a phase II study. Development In 1966, Charlotte Friend published her observati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrons
The electron ( or ) is a subatomic particle with a negative one elementary electric charge. Electrons belong to the first generation of the lepton particle family, and are generally thought to be elementary particles because they have no known components or substructure. The electron's mass is approximately 1/1836 that of the proton. Quantum mechanical properties of the electron include an intrinsic angular momentum ( spin) of a half-integer value, expressed in units of the reduced Planck constant, . Being fermions, no two electrons can occupy the same quantum state, in accordance with the Pauli exclusion principle. Like all elementary particles, electrons exhibit properties of both particles and waves: They can collide with other particles and can be diffracted like light. The wave properties of electrons are easier to observe with experiments than those of other particles like neutrons and protons because electrons have a lower mass and hence a longer de Broglie wav ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aromaticity
In chemistry, aromaticity is a chemical property of cyclic ( ring-shaped), ''typically'' planar (flat) molecular structures with pi bonds in resonance (those containing delocalized electrons) that gives increased stability compared to saturated compounds having single bonds, and other geometric or connective non-cyclic arrangements with the same set of atoms. Aromatic rings are very stable and do not break apart easily. Organic compounds that are not aromatic are classified as aliphatic compounds—they might be cyclic, but only aromatic rings have enhanced stability. The term ''aromaticity'' with this meaning is historically related to the concept of having an aroma, but is a distinct property from that meaning. Since the most common aromatic compounds are derivatives of benzene (an aromatic hydrocarbon common in petroleum and its distillates), the word ''aromatic'' occasionally refers informally to benzene derivatives, and so it was first defined. Nevertheless, many non-be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cation
An ion () is an atom or molecule with a net electrical charge. The charge of an electron is considered to be negative by convention and this charge is equal and opposite to the charge of a proton, which is considered to be positive by convention. The net charge of an ion is not zero because its total number of electrons is unequal to its total number of protons. A cation is a positively charged ion with fewer electrons than protons while an anion is a negatively charged ion with more electrons than protons. Opposite electric charges are pulled towards one another by electrostatic force, so cations and anions attract each other and readily form ionic compounds. Ions consisting of only a single atom are termed atomic or monatomic ions, while two or more atoms form molecular ions or polyatomic ions. In the case of physical ionization in a fluid (gas or liquid), "ion pairs" are created by spontaneous molecule collisions, where each generated pair consists of a free electron and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ronald Breslow - National Medal Of Science, 1991
Ronald is a masculine given name derived from the Old Norse '' Rögnvaldr'', Hanks; Hardcastle; Hodges (2006) p. 234; Hanks; Hodges (2003) § Ronald. or possibly from Old English '' Regenweald''. In some cases ''Ronald'' is an Anglicised form of the Gaelic '' Raghnall'', a name likewise derived from ''Rögnvaldr''. The latter name is composed of the Old Norse elements ''regin'' ("advice", "decision") and ''valdr'' ("ruler"). ''Ronald'' was originally used in England and Scotland, where Scandinavian influences were once substantial, although now the name is common throughout the English-speaking world. A short form of ''Ronald'' is ''Ron''. Pet forms of ''Ronald'' include ''Roni'' and ''Ronnie''. ''Ronalda'' and ''Rhonda'' are feminine forms of ''Ronald''. ''Rhona'', a modern name apparently only dating back to the late nineteenth century, may have originated as a feminine form of ''Ronald''. Hanks; Hardcastle; Hodges (2006) pp. 230, 408; Hanks; Hodges (2003) § Rhona. The names ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Legacy
In law, a legacy is something held and transferred to someone as their inheritance, as by will and testament. Personal effects, family property, marriage property or collective property gained by will of real property. Legacy or legacies may refer to: Arts, media and entertainment People * “Legacy”, a.k.a. Big Popp, a legend in Natick M.A. Comics * " Batman: Legacy", a 1996 Batman storyline * '' DC Universe: Legacies'', a comic book series from DC Comics written by Len Wein * ''Legacy'', a 1999 quarterly series from Antarctic Press * ''Legacy'', a 2003–2005 series released by Dabel Brothers Productions * Legacy, an alternate name for the DC supervillain Wizard who leads the Injustice Society IV team * Legacy (Marvel Comics), an alias used by Genis-Vell, better known as Captain Marvel * Legacy Virus, a fictional virus from the Marvel Universe * Marvel Legacy, a comic book line introduced in 2017 * '' Star Wars: Legacy'', a 2006 series from Dark Horse * '' X-Men: Legacy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Professor (Columbia)
This is a partially sorted list of notable persons who have had ties to Columbia University. For further listing of notable Columbians see: Notable alumni at Columbia College of Columbia University; Columbia University School of General Studies; Columbia Law School; Columbia Business School; Columbia University Graduate School of Journalism; Columbia Graduate School of Architecture, Planning and Preservation; Columbia University College of Physicians and Surgeons; Columbia University Graduate School of Education (Teachers College); Fu Foundation School of Engineering and Applied Science; Columbia Graduate School of Arts and Sciences; Columbia University School of Professional Studies; Columbia University School of the Arts; the School of International and Public Affairs; and Barnard College. The following lists are incomplete. Nobel laureates As of October 2020, 84 Nobel laureates were affiliated with Columbia University.Niklas Magnusson and Josiane KremerRoth, Shapley Win Nobel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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