Ron Heeren
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Ron Heeren
Ron M.A. Heeren (born 1965, Tilburg) is a Dutch scientist in mass spectrometry imaging. He is currently a distinguished professor at Maastricht University and the scientific director of the Multimodal Molecular Imaging Institute (M4I), where he heads the division of Imaging Mass Spectrometry. Scientific career Heeren obtained a PhD degree in Technical Physics at the University of Amsterdam in 1992 under the supervision of Aart Kleyn. He led a AMOLF, FOM-AMOLF research group on macromolecular ion physics and biomolecular imaging mass spectrometry (1995–2014). He was also professor at the chemistry faculty of Utrecht University in 2001–2019. Between 1995 and 2015, he worked on new approaches towards high spatial resolution and high-throughput molecular imaging mass spectrometry using secondary ion mass spectrometry (SIMS) and Matrix-assisted laser desorption/ionization, matrix-assisted laser desorption and ionization (MALDI). Heeren has coauthored over 300 peer-reviewed ...
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Tilburg
Tilburg () is a city and municipality in the Netherlands, in the southern province of North Brabant. With a population of 222,601 (1 July 2021), it is the second-largest city or municipality in North Brabant after Eindhoven and the seventh-largest in the Netherlands as a whole. Tilburg University is located in Tilburg, as are Avans University of Applied Sciences and Fontys University of Applied Sciences. Tilburg is known for its ten-day-long funfair, held in July each year. The Monday during the funfair is called "Roze Maandag" (Pink Monday) and is primarily LGBT-oriented. There are three railway stations within the municipality: Tilburg, Tilburg Universiteit and Tilburg Reeshof. The "Spoorzone" area around Tilburg Central station, once a Dutch Railways train maintenance yard, has been purchased by the city and is being transformed into an urban zone. History Little is known about the beginnings of Tilburg. The name ''Tilliburg'' first appeared in documents dating f ...
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Secondary Ion Mass Spectrometry
Secondary-ion mass spectrometry (SIMS) is a technique used to analyze the composition of solid surfaces and thin films by sputtering the surface of the specimen with a focused primary ion beam and collecting and analyzing ejected secondary ions. The mass/charge ratios of these secondary ions are measured with a mass spectrometer to determine the elemental, isotopic, or molecular composition of the surface to a depth of 1 to 2 nm. Due to the large variation in ionization probabilities among elements sputtered from different materials, comparison against well-calibrated standards is necessary to achieve accurate quantitative results. SIMS is the most sensitive surface analysis technique, with elemental detection limits ranging from parts per million to parts per billion. History In 1910 British physicist J. J. Thomson observed a release of positive ions and neutral atoms from a solid surface induced by ion bombardment. Improved vacuum pump technology in the 1940s enabled the fi ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Academic Staff Of Maastricht University
An academy (Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy, founded approximately 385 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, ''Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions into a method of teaching philosophy and in 387 BC, established what is known today as the Old Academy. By extension, ''academia'' has come to mean the accumulation, dev ...
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21st-century Dutch Chemists
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius ( AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman em ...
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People From Tilburg
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of ...
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1965 Births
Events January–February * January 14 – The Prime Minister of Northern Ireland and the Taoiseach of the Republic of Ireland meet for the first time in 43 years. * January 20 ** Lyndon B. Johnson is Second inauguration of Lyndon B. Johnson, sworn in for a full term as President of the United States. ** Indonesian President Sukarno announces the withdrawal of the Indonesian government from the United Nations. * January 30 – The Death and state funeral of Winston Churchill, state funeral of Sir Winston Churchill takes place in London with the largest assembly of dignitaries in the world until the 2005 funeral of Pope John Paul II. * February 4 – Trofim Lysenko is removed from his post as director of the Institute of Genetics at the Russian Academy of Sciences, Academy of Sciences in the Soviet Union. Lysenkoism, Lysenkoist theories are now treated as pseudoscience. * February 12 ** The African and Malagasy Republic, Malagasy Common Organization ('; OCA ...
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Lezanne Ooi
Lezanne Ooi is an Australian neuroscientist who is Professor and Head of Neurodevelopment at the University of Wollongong. Her research considers the development of cellular imaging techniques to understand neurodegenerative disease. Early life and education Ooi trained in the United Kingdom. She studied biochemistry at the University of York, where she worked with GlaxoSmith Kline. When Ooi was studying neuroscience, her grandmother was diagnosed with dementia, which motivated her to purse a career studying neurodegenerative disease. She completed her doctoral research on the transcriptional repressor REST (Repressor Element 1-Silencing Transcription factor) at the University of Leeds. She remained there as a postdoctoral researcher, where she studied cardiac hypertrophy and developed cellular imaging techniques to understand neuronal function. Her research showed that atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) became abnormally high in people with h ...
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Netherlands Proteomics Centre
The Netherlands Proteomics Centre (NPC) is a Dutch people, Dutch research center in the field of proteomics. The research is focused on the proteome, the entire set of proteins expressed by a genome, Cell (biology), cell, Tissue (biology), tissue or organism. The NPC was established by Prof. Dr. Albert J.R. Heck, Albert Heck in 2003 and is located in the city of Utrecht. NPC is part of the Netherlands Genomics Initiative (NGI). Cooperating institutions Within NPC there is a cooperation between seven universities, four academic medical centers and a number of biotechnology companies: * Utrecht University (UU) * University Medical Center Utrecht (UMCU) * University of Groningen (RUG) * Leiden University (LU) * Leiden University Medical Center (LUMC) * Delft University of Technology (TU Delft) * Radboud University Nijmegen (RUN) * University of Amsterdam (UvA) * Academic Medical Center (AMC) * Wageningen University and Research Centre (WUR/PRI) * Erasmus MC * Dutch Cancer Institu ...
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Medipix
Medipix is a family of photon counting and particle tracking pixel detectors developed by an international collaboration, hosted by CERN. Design These are hybrid detectors as a semiconductor sensor layer is bonded to a processing electronics layer. The sensor layer is a semiconductor, such as silicon, GaAs, or CdTe in which the incident radiation makes an electron hole/cloud. The charge is then collected to pixel electrodes and, via bump bonds, conducted to the CMOS electronics layer. The pixel electronics first amplifies the signal and then compares the signal amplitude with a pre-set discrimination level (an energy threshold). The subsequent signal processing depends on the type of device. A standard Medipix detector increases the counter in the appropriate pixel if the signal is above the discrimination level. The Medipix device also contains an upper discrimination level and hence only signals within a range of amplitude could be accepted (within an energy window). Timepi ...
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Mass Spectrometry Imaging
Mass spectrometry imaging (MSI) is a technique used in mass spectrometry to visualize the spatial distribution of molecules, as biomarkers, metabolites, peptides or proteins by their molecular masses. After collecting a mass spectrum at one spot, the sample is moved to reach another region, and so on, until the entire sample is scanned. By choosing a peak in the resulting spectra that corresponds to the compound of interest, the MS data is used to map its distribution across the sample. This results in pictures of the spatially resolved distribution of a compound pixel by pixel. Each data set contains a veritable gallery of pictures because any peak in each spectrum can be spatially mapped. Despite the fact that MSI has been generally considered a qualitative method, the signal generated by this technique is proportional to the relative abundance of the analyte. Therefore, quantification is possible, when its challenges are overcome. Although widely used traditional methodologies ...
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Mauritshuis
The Mauritshuis (; en, Maurice House) is an art museum in The Hague, Netherlands. The museum houses the Royal Cabinet of Paintings which consists of 854 objects, mostly Dutch Golden Age paintings. The collection contains works by Johannes Vermeer, Rembrandt van Rijn, Jan Steen, Paulus Potter, Frans Hals, Jacob van Ruisdael, Hans Holbein the Younger, and others. Originally, the 17th-century building was the residence of count John Maurice of Nassau. It is now the property of the government of the Netherlands and is listed in the top 100 Dutch heritage sites. History In 1631, John Maurice, Prince of Nassau-Siegen, a cousin of stadtholder Frederick Henry, bought a plot bordering the Binnenhof and the adjacent Hofvijver pond in The Hague, at that time the political centre of the Dutch Republic. On the plot, the Mauritshuis was built as a home between 1636 and 1641, during John Maurice's governorship of Dutch Brazil. The Dutch Classicist building was designed by the Dutch arch ...
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