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Ro05-2904
Triflunordazepam (also known as Ro5-2904) is a drug which is a benzodiazepine derivative with high GABAA receptor affinity, and has anticonvulsant effects. See also *Nordazepam *Triflubazam Triflubazam is a drug which is a 1,5- benzodiazepine derivative, related to clobazam. It has sedative and anxiolytic effects, with a long half-life and duration of action. See also * Benzodiazepine *Clobazam Clobazam, sold under the brand ... References Benzodiazepines GABAA receptor positive allosteric modulators Hoffmann-La Roche brands Lactams Trifluoromethyl compounds {{sedative-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benzodiazepine
Benzodiazepines (BZD, BDZ, BZs), sometimes called "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed to treat conditions such as anxiety disorders, insomnia, and seizures. The first benzodiazepine, chlordiazepoxide (Librium), was discovered accidentally by Leo Sternbach in 1955 and was made available in 1960 by Hoffmann–La Roche, who soon followed with diazepam (Valium) in 1963. By 1977, benzodiazepines were the most prescribed medications globally; the introduction of selective serotonin reuptake inhibitors (SSRIs), among other factors, decreased rates of prescription, but they remain frequently used worldwide. Benzodiazepines are depressants that enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA receptor, resulting in sedative, hypnotic ( sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant properties. High doses o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
