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Rickettsia Peacockii
''Rickettsia peacockii'' is a species of gram negative Alphaproteobacteria of the ''spotted fever group'', identified from Rocky Mountain wood ticks ('' Dermacentor andersoni''). Its type strain is SkalkahoT. The organism is passed transstadially and transovarially, and infections are localized in ovarial tissues. References Further reading * * * Zoonoses Rickettsiaceae Bacteria described in 1997 {{Alphaproteobacteria-stub ...
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Gram Negative
The gram (originally gramme; SI unit symbol g) is a unit of mass in the International System of Units (SI) equal to one one thousandth of a kilogram. Originally defined as of 1795 as "the absolute weight of a volume of pure water equal to the cube of the hundredth part of a metre the_temperature_of_Melting_point.html" "title="Melting_point_of_water.html" ;"title="Cubic_centimetre.html" ;"title=" Cubic centimetre">cm3], and at Melting point of water">the temperature of Melting point">melting ice", the defining temperature (~0 °C) was later changed to 4 °C, the temperature of maximum density of water. However, by the late 19th century, there was an effort to make the Base unit (measurement), base unit the kilogram and the gram a derived unit. In 1960, the new International System of Units defined a ''gram'' as one one-thousandth of a kilogram (i.e., one gram is Scientific notation, 1×10−3 kg). The kilogram, as of 2019, is defined by the International Bur ...
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Alphaproteobacteria
Alphaproteobacteria is a class of bacteria in the phylum Pseudomonadota (formerly Proteobacteria). The Magnetococcales and Mariprofundales are considered basal or sister to the Alphaproteobacteria. The Alphaproteobacteria are highly diverse and possess few commonalities, but nevertheless share a common ancestor. Like all ''Proteobacteria'', its members are gram-negative and some of its intracellular parasitic members lack peptidoglycan and are consequently gram variable. Characteristics The Alphaproteobacteria are a diverse taxon and comprises several phototrophic genera, several genera metabolising C1-compounds (''e.g.'', ''Methylobacterium'' spp.), symbionts of plants (''e.g.'', ''Rhizobium'' spp.), endosymbionts of arthropods (''Wolbachia'') and intracellular pathogens (''e.g. Rickettsia''). Moreover, the class is sister to the protomitochondrion, the bacterium that was engulfed by the eukaryotic ancestor and gave rise to the mitochondria, which are organelles in eukaryotic ce ...
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Dermacentor Andersoni
''Dermacentor andersoni'', commonly known as the Rocky Mountain wood tick, is a hard tick, or member of the Ixodidae family, with three life stages including larvae, nymph, and finally adult An adult is a human or other animal that has reached full growth. In human context, the term ''adult'' has meanings associated with social and legal concepts. In contrast to a " minor", a legal adult is a person who has attained the age of major ..., or, more entomologically, imago. This tick is generally located in the northwest United States and southwest Canada along the Rocky Mountains. This tick is generally a vector for Colorado tick fever, but can also be a vector for Rocky Mountain spotted fever and tularemia. During the larval and nymphal stages, the tick does not feed on humans, but during the adult stage, it will. Prevention of infections associated with these ticks is based on control of exposure to the vector, including wearing proper clothing when in woods/wet areas, ...
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Transstadial Transmission
Transstadial transmission occurs when a pathogen remains with the vector from one life stage ("stadium") to the next. For example, the bacteria ''Borrelia burgdorferi'', the causative agent for Lyme disease, infects the tick vector as a larva, and the infection is maintained when it molts to a nymph and later develops as an adult. This type of transmission is seen in other parasites like viruses or ''Rickettsia''. In addition to ticks, mites are another common vector. Some sources consider transstadial transmission a type of horizontal transmission, whereas other sources consider it vertical or partial vertical transmission. Transstadial blockage could be considered the opposite of transstadial transmission, where the parasite cannot be carried over from one life stage to the next. For example, viruses that undergo transstadial blockage will have decreased infectivity in molting insects. See also *Transovarial transmission Transovarial or transovarian transmission (transmission f ...
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Transovarial Transmission
Transovarial or transovarian transmission (transmission from parent to offspring via the ovaries) occurs in certain arthropod vectors as they transmit pathogens from parent to offspring. This process, used by a wide variety of parasites, is also known as vertical transmission. For example, ''Rickettsia rickettsii'', carried within ticks, is passed on from parent to offspring tick by transovarial transmission. This is in contrast to parasites such as ''Rickettsia prowazekii,'' which are not passed on by transovarian transmission due to killing the vector that carries it (in this case, the human louse). Other examples of parasites that use this mechanism of transmission include the aedes mosquito vector of the yellow fever virus and in phlebotomine sandflies that transmit pappataci fever. Richard Dawkins in "The Extended Phenotype" notes that "bacterial endosymbionts of insects which are transmitted transovarially" share an interest in the "success of their host's gametes.....as we ...
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Ovary
The ovary is an organ in the female reproductive system that produces an ovum. When released, this travels down the fallopian tube into the uterus, where it may become fertilized by a sperm. There is an ovary () found on each side of the body. The ovaries also secrete hormones that play a role in the menstrual cycle and fertility. The ovary progresses through many stages beginning in the prenatal period through menopause. It is also an endocrine gland because of the various hormones that it secretes. Structure The ovaries are considered the female gonads. Each ovary is whitish in color and located alongside the lateral wall of the uterus in a region called the ovarian fossa. The ovarian fossa is the region that is bounded by the external iliac artery and in front of the ureter and the internal iliac artery. This area is about 4 cm x 3 cm x 2 cm in size.Daftary, Shirish; Chakravarti, Sudip (2011). Manual of Obstetrics, 3rd Edition. Elsevier. pp. 1-16. . The ovari ...
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Zoonoses
A zoonosis (; plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a bacterium, virus, parasite or prion) that has jumped from a non-human (usually a vertebrate) to a human. Typically, the first infected human transmits the infectious agent to at least one other human, who, in turn, infects others. Major modern diseases such as Ebola virus disease and salmonellosis are zoonoses. HIV was a zoonotic disease transmitted to humans in the early part of the 20th century, though it has now evolved into a separate human-only disease. Most strains of influenza that infect humans are human diseases, although many strains of bird flu and swine flu are zoonoses; these viruses occasionally recombine with human strains of the flu and can cause pandemics such as the 1918 Spanish flu or the 2009 swine flu. ''Taenia solium'' infection is one of the neglected tropical diseases with public health and veterinary concern in ende ...
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Rickettsiaceae
The Rickettsiaceae are a family of bacteria. The genus ''Rickettsia'' is the most prominent genus within the family. The bacteria that eventually formed the mitochondrion (an organelle in eukaryotic cells) is believed to have originated from this family. Most human pathogens in this family are in genus ''Rickettsia''. They spend part of their lifecycle in the bodies of arthropods such as ticks or lice, and are then transmitted to humans or other mammals by the bite of the arthropod. It contains Gram-negative bacteria, very sensitive to environmental exposure, thus is adapted to obligate intracellular infection. ''Rickettsia rickettsii'' is considered the prototypical infectious organism in the group. Genomics Comparative genomic analysis has identified three proteins, RP030, RP187 and RP192, which are uniquely found in members of the family Rickettsiaceae and serve as molecular markers for this family. In addition, conserved signature indels in a number of proteins includi ...
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