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Richard Pestell
Richard G. Pestell is an Australian American Oncology, oncologist and Endocrinology, endocrinologist who is Distinguished Professor, Translational Medical Research, and the President of the Pennsylvania Cancer and Regenerative Medicine Research Center at the Baruch S. Blumberg Institute. He was previously Executive Vice President of Thomas Jefferson University and Director of the Sidney Kimmel Cancer Center of Thomas Jefferson University. Pestell was appointed an Officer of the Order of Australia in the 2019 Queen's Birthday Honours for distinguished service to medicine and medical education. Education and early career A native of Perth, Western Australia, Pestell attended Christ Church Grammar School. He attended the University of Western Australia School of Medicine, receiving his M.B.B.S. He conducted clinical training in internal medicine, oncology and endocrinology. He was awarded the Fellow of the Royal Australian College of Physicians (FRACP) in 1989. He received a Ph.D. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Perth, Western Australia
Perth is the capital and largest city of the Australian state of Western Australia. It is the fourth most populous city in Australia and Oceania, with a population of 2.1 million (80% of the state) living in Greater Perth in 2020. Perth is part of the South West Land Division of Western Australia, with most of the metropolitan area on the Swan Coastal Plain between the Indian Ocean and the Darling Scarp. The city has expanded outward from the original British settlements on the Swan River, upon which the city's central business district and port of Fremantle are situated. Perth is located on the traditional lands of the Whadjuk Noongar people, where Aboriginal Australians have lived for at least 45,000 years. Captain James Stirling founded Perth in 1829 as the administrative centre of the Swan River Colony. It was named after the city of Perth in Scotland, due to the influence of Stirling's patron Sir George Murray, who had connections with the area. It gained city stat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Avon Foundation
Avon Products, Inc. or simply known as Avon, is an American-British multinational cosmetics, skin care, fragrance and personal care company, based in London. It sells directly to the public. Avon had annual sales of $9.1 billion worldwide in 2020. It is the fourteenth-largest beauty company and, with 6.4 million representatives, is the second largest direct-selling enterprise in the world (after Amway). The company's CEO is Angela Cretu, who was appointed to the position in January 2020. In May 2019, the multinational company Natura & Co announced its intent to acquire Avon; the deal closed in January 2020. Following the merger, existing Natura shareholders held 73% of the combined company, Natura Holding S.A., with former Avon shareholders owning 27%. At merger completion, Avon became a privately held company, common stock was removed from the NYSE trading. History Avon's founder, David H. McConnell, initially sold books as a door-to-door salesman to New York homes. In Sep ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albert Green (Australian Politician)
Albert Ernest Green (21 December 1869 – 2 October 1940) was an Australian politician. He arrived in Western Australia in 1895, and represented the Kalgoorlie area in both state and federal parliaments for the Australian Labor Party, as well as serving as Minister for Defence (Australia), Minister for Defence and later Postmaster-General of Australia, Postmaster-General in the Scullin Ministry. Biography Green was born and went to primary school in Avoca, Victoria, but left school to work for a telephone company in Ballarat, Victoria, Ballarat and later in the family's bricklaying business. He travelled in the United States and Central America between 1889 and 1895 and as a result was known as "Texas". He was active in the brickmasons' society at San Francisco, and it was even suggested by one contemporary source that he had assisted revolutionary insurgents in Guatemala. In June 1895, he moved to Western Australia and established a branch of the Australian Natives' Association ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Order Of Australia
The Order of Australia is an honour that recognises Australian citizens and other persons for outstanding achievement and service. It was established on 14 February 1975 by Elizabeth II, Queen of Australia, on the advice of the Australian Government. Before the establishment of the order, Australian citizens received British honours. The Monarch of Australia is sovereign head of the order, while the Governor-General of Australia is the principal companion/dame/knight (as relevant at the time) and chancellor of the order. The governor-general's official secretary, Paul Singer (appointed August 2018), is secretary of the order. Appointments are made by the governor-general on behalf of the Monarch of Australia, based on recommendations made by the Council of the Order of Australia. Recent knighthoods and damehoods were recommended to the governor-general by the Prime Minister of Australia. Levels of membership The order is divided into a general and a military division. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the betterment of all humanity. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists. The society chose William Charles Redfield as their first president because he had proposed the most comprehensive plans for the organization. According to the first constitution which was agreed to at the September 20 meeting, the goal of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American College Of Physicians
The American College of Physicians (ACP) is a national organization of internists, who specialize in the diagnosis, treatment, and care of adults.Sokanu "What is an Internist?" Retrieved October 20, 2014 With 161,000 members, ACP is the largest medical-specialty organization and second-largest physician group in the United States, after the American Medical Association.Osmosis "Prep for the Medicine Shelf". Retrieved October 20, 2014 Its flagship journal, the ''Annals of Internal Medicine'', is considered one of the five top medical journals in the United States and Britain. Mission and history Founded in 1915, ACP's stated mission is to "enhance the quality and effectiveness of health care by fostering excellence and professionalism in the practice of medicine." In 1998, it merged with the American Society of Internal Medicine (ASIM). ASIM's focus on the economic, political, and social aspects of medical care both enlarged and complemented its mission. Known as ACP-ASIM from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
College Of Physicians Of Philadelphia
The College of Physicians of Philadelphia is the oldest private medical society in the United States. Founded in 1787 by 24 Philadelphia physicians "to advance the Science of Medicine, and thereby lessen human misery, by investigating the diseases and remedies which are peculiar to our country" and to promote "order and uniformity in the practice of Physick," it has made important contributions to medical education and research. The College hosts the Mütter Museum, a gallery of 19th-century specimens, teaching models, instruments, and photographs, as well as the Historical Medical Library, which is one of the country's oldest medical libraries. The College of Physicians of Philadelphia Building, designed by the firm of Cope & Stewardson and built in 1909, was designated a U.S. National Historic Landmark in October, 2008. It was also then listed on the National Register of Historic Places. Current programs The College remains a private membership organization of physicians, whose ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Doctor Honoris Causa
An honorary degree is an academic degree for which a university (or other degree-awarding institution) has waived all of the usual requirements. It is also known by the Latin phrases ''honoris causa'' ("for the sake of the honour") or ''ad honorem '' ("to the honour"). The degree is typically a doctorate or, less commonly, a master's degree, and may be awarded to someone who has no prior connection with the academic institution or no previous postsecondary education. An example of identifying a recipient of this award is as follows: Doctorate in Business Administration (''Hon. Causa''). The degree is often conferred as a way of honouring a distinguished visitor's contributions to a specific field or to society in general. It is sometimes recommended that such degrees be listed in one's curriculum vitae (CV) as an award, and not in the education section. With regard to the use of this honorific, the policies of institutions of higher education generally ask that recipients ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Society Of Medicine
The Royal Society of Medicine (RSM) is a medical society in the United Kingdom, headquartered in London. History The Society was established in 1805 as Medical and Chirurgical Society of London, meeting in two rooms in barristers’ chambers at Gray's Inn and then moving to Lincoln's Inn Fields where it stayed for 25 years. In 1834 the Society moved to Berners Street and was granted a Royal Charter by King William IV. In 1889 under the leadership of Sir John MacAlister, a Building Committee chaired by Timothy Holmes supervised the move of the quarters of the Society from Berners Street to 20 Hanover Square. In 1905 an eleven-member committee headed by Sir Richard Douglas Powell organised the celebration of the Society's centenary. Two years later the Royal Medical and Chirurgical Society of London came together with seventeen specialist medical societies and, with a supplementary Royal Charter granted by Edward VII, became the Royal Society of Medicine. In 1910 the Society ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Society For Clinical Investigation
The American Society for Clinical Investigation (ASCI), established in 1908, is one of the oldest and most respected medical honor societies in the United States. Organization and purpose The ASCI is an honorary society to which more than 2,800 physician-scientists from all medical specialties belong. Prospective members are proposed by standing members of the society and elected to ASCI on the basis of an outstanding record of scholarly achievement in biomedical research. The ASCI includes physician-scientists who are active clinically, in basic research, or in teaching. Many of its senior members are widely recognized leaders in academic medicine. As of 2015 the membership of ASCI has included 417 members of the National Academy of Medicine, 191 members of the National Academy of Sciences, Engineering, and Medicine, 40 Lasker Award winners, and 19 Nobel laureates. The ASCI supports the research into basic mechanisms and/or treatment of human diseases, and to the education of fut ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DACH1
Dachshund homolog 1, also known as DACH1, is a protein which in humans is encoded by the ''DACH1'' gene. DACH1 has been shown to interact with Ubc9, Smad4, and NCoR. Structure Gene structure . This protein coding gene has 760 amino acid protein, and an observed molecular weight of 52 kDa. Dachshund Family transcription factor 1 is encoded by DACH gene, who spans 400kDa and is encoded by 12 exons. This gene is located, in humans, in chromosome 13 (13q22). It encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression, mRNA translation, coactivator binding, and cell fate determination during development. Multiple transcript variants encoding different isoforms have been found for this gene. Four alternatively spliced transcripts encoding different isoforms have been described for this gene.DACH1 mRNA was detected in multiple human tissues, including kidney and heart. Dach1 is located in nuclear and cytoplasmic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
P21Cip1
p21Cip1 (alternatively p21Waf1), also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1, is a cyclin-dependent kinase inhibitor (CKI) that is capable of inhibiting all cyclin/CDK complexes, though is primarily associated with inhibition of CDK2. p21 represents a major target of p53 activity and thus is associated with linking DNA damage to cell cycle arrest.Waldman, Todd, Kenneth W. Kinzler, and Bert Vogelstein. "p21 is necessary for the p53-mediated G1 arrest in human cancer cells." Cancer research 55.22 (1995): 5187-5190. This protein is encoded by the ''CDKN1A'' gene located on chromosome 6 (6p21.2) in humans. Function CDK inhibition p21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclin-CDK2, -CDK1, and -CDK4 /6 complexes, and thus functions as a regulator of cell cycle progression at G1 and S phase. The binding of p21 to CDK complexes occurs through p21's N-terminal dom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
