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Richard Losick
Richard Marc Losick ( ; born 1943) is an American molecular biologist. He is the Maria Moors Cabot Professor of Biology at Harvard University, a Howard Hughes Medical Institute Professor. He is especially noted for his investigations of endospore formation in Gram positive organisms such as ''Bacillus subtilis''. Education and career Losick received his AB in Chemistry from Princeton University in 1965, and his PhD in biochemistry from Massachusetts Institute of Technology in 1969. Following his graduate studies, Losick was named a Junior Fellow of the Harvard Society of Fellows. He joined the Harvard faculty in 1972. He has held the position of chairman in the Departments of Cellular and Developmental Biology and Molecular and Cellular Biology. Along with Daniel Kahne, Robert Lue, and Susan Mango, he teaches Life Sciences 1a, an introductory biology and chemistry course, which was the fourth largest lecture course taught at Harvard College in 2015. Research Losick's research ...
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Richard Losick
Richard Marc Losick ( ; born 1943) is an American molecular biologist. He is the Maria Moors Cabot Professor of Biology at Harvard University, a Howard Hughes Medical Institute Professor. He is especially noted for his investigations of endospore formation in Gram positive organisms such as ''Bacillus subtilis''. Education and career Losick received his AB in Chemistry from Princeton University in 1965, and his PhD in biochemistry from Massachusetts Institute of Technology in 1969. Following his graduate studies, Losick was named a Junior Fellow of the Harvard Society of Fellows. He joined the Harvard faculty in 1972. He has held the position of chairman in the Departments of Cellular and Developmental Biology and Molecular and Cellular Biology. Along with Daniel Kahne, Robert Lue, and Susan Mango, he teaches Life Sciences 1a, an introductory biology and chemistry course, which was the fourth largest lecture course taught at Harvard College in 2015. Research Losick's research ...
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RNA Polymerase
In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that synthesizes RNA from a DNA template. Using the enzyme helicase, RNAP locally opens the double-stranded DNA so that one strand of the exposed nucleotides can be used as a template for the synthesis of RNA, a process called transcription. A transcription factor and its associated transcription mediator complex must be attached to a DNA binding site called a promoter region before RNAP can initiate the DNA unwinding at that position. RNAP not only initiates RNA transcription, it also guides the nucleotides into position, facilitates attachment and elongation, has intrinsic proofreading and replacement capabilities, and termination recognition capability. In eukaryotes, RNAP can build chains as long as 2.4 million nucleotides. RNAP produces RNA that, functionally, is either for protein coding, i.e. messenger RNA (mRNA); or n ...
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Phi Beta Kappa
The Phi Beta Kappa Society () is the oldest academic honor society in the United States, and the most prestigious, due in part to its long history and academic selectivity. Phi Beta Kappa aims to promote and advocate excellence in the liberal arts and sciences, and to induct the most outstanding students of arts and sciences at only select American colleges and universities. It was founded at the College of William and Mary on December 5, 1776, as the first collegiate Greek-letter fraternity and was among the earliest collegiate fraternal societies. Since its inception, 17 U.S. Presidents, 40 U.S. Supreme Court Justices, and 136 Nobel Laureates have been inducted members. Phi Beta Kappa () stands for ('), which means "Wisdom it. love of knowledgeis the guide it. helmsmanof life". Membership Phi Beta Kappa has chapters in only about 10% of American higher learning institutions, and only about 10% of these schools' Arts and Sciences graduates are invited to join the society. ...
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American Society For Microbiology
The American Society for Microbiology (ASM), originally the Society of American Bacteriologists, is a professional organization for scientists who study viruses, bacteria, fungi, algae, and protozoa as well as other aspects of microbiology. It was founded in 1899. The Society publishes a variety of scientific journals, textbooks, and other educational materials related to microbiology and infectious diseases. ASM organizes annual meetings, as well as workshops and professional development opportunities for its members. History ASM was founded in 1899 under the name the "Society of American Bacteriologists." In December 1960, it was renamed the "American Society for Microbiology." Mission ASM's mission is "to promote and advance the microbial sciences." The society seeks to accomplish this mission through: * Publishing highly-cited publications * Running multi-disciplinary meetings * Deploying resources and expertise around the world * Advocating for scientific research * Fost ...
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American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the betterment of all humanity. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists. The society chose William Charles Redfield as their first president because he had proposed the most comprehensive plans for the organization. According to the first constitution which was agreed to at the September 20 meeting, the goal of ...
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American Academy Of Arts And Sciences
The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other Founding Fathers of the United States. It is headquartered in Cambridge, Massachusetts. Membership in the academy is achieved through a thorough petition, review, and election process. The academy's quarterly journal, ''Dædalus'', is published by MIT Press on behalf of the academy. The academy also conducts multidisciplinary public policy research. History The Academy was established by the Massachusetts legislature on May 4, 1780, charted in order "to cultivate every art and science which may tend to advance the interest, honor, dignity, and happiness of a free, independent, and virtuous people." The sixty-two incorporating fellows represented varying interests and high standing in the political, professional, and commercial secto ...
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National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scien ...
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The Camille And Henry Dreyfus Foundation
The Camille and Henry Dreyfus Foundation is a New York City-based foundation founded in 1946 by chemist and investor Camille Dreyfus in honour of his brother, Henry Dreyfus. The two men invented the acetate yarn Celanese, and Henry Dreyfus was founder and chairman of British Celanese, parent of the Celanese Corporation of America. Following Camille's death in 1956, his wife, the opera singer Jean Tennyson, served as the foundation's president until her death in 1991. In 1971, the foundation sold a significant part of its holdings in the Celanese company. The foundation makes grants and awards prizes in support of chemistry research and education. These prizes include the Dreyfus Prize in the Chemical Sciences, Camille Dreyfus Teacher-Scholar Awards, Henry Dreyfus Teacher-Scholar Awards, Machine Learning in the Chemical Sciences and Engineering, Jean Dreyfus Lectureship for Undergraduate Institutions. The foundation also sponsors two awards through the American Chemical Societ ...
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Camille Dreyfus Teacher-Scholar Awards
The Camille Dreyfus Teacher-Scholar Awards are awards given to early-career researchers in chemistry by The Camille and Henry Dreyfus Foundation, Inc. "to support the research and teaching careers of talented young faculty in the chemical sciences." The Dreyfus Teacher-Scholar program began in 1970. In 1994, the program was divided into two parallel awards: The Camille Dreyfus Teacher-Scholar Awards Program, aimed at research universities, and the Henry Dreyfus Teacher-Scholar Awards Program, directed at primarily undergraduate institutions. This list compiles all the pre-1994 Teacher-Scholars, and the subsequent Camille Dreyfus Teacher-Scholars. The annually presented awards consist of a monetary prize of $75,000, which was increased to $100,000 starting in 2019. Seven winners of the Camille Dreyfus Teacher-Scholar Awards have gone on to win the Nobel Prize in Chemistry, including Paul L. Modrich, Richard R. Schrock, Robert H. Grubbs, K. Barry Sharpless, Ahmed H. Zewail, Mario J. ...
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Extracellular Matrix
In biology, the extracellular matrix (ECM), also called intercellular matrix, is a three-dimensional network consisting of extracellular macromolecules and minerals, such as collagen, enzymes, glycoproteins and hydroxyapatite that provide structural and biochemical support to surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM. The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the Interstitial fluid, interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest ...
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Staphylococcus Aureus
''Staphylococcus aureus'' is a Gram-positive spherically shaped bacterium, a member of the Bacillota, and is a usual member of the microbiota of the body, frequently found in the upper respiratory tract and on the skin. It is often positive for catalase and nitrate reduction and is a facultative anaerobe that can grow without the need for oxygen. Although ''S. aureus'' usually acts as a commensal of the human microbiota, it can also become an opportunistic pathogen, being a common cause of skin infections including abscesses, respiratory infections such as sinusitis, and food poisoning. Pathogenic strains often promote infections by producing virulence factors such as potent protein toxins, and the expression of a cell-surface protein that binds and inactivates antibodies. ''S. aureus'' is one of the leading pathogens for deaths associated with antimicrobial resistance and the emergence of antibiotic-resistant strains, such as methicillin-resistant ''S. aureus'' (MRSA ...
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Biofilm
A biofilm comprises any syntrophic consortium of microorganisms in which cells stick to each other and often also to a surface. These adherent cells become embedded within a slimy extracellular matrix that is composed of extracellular polymeric substances (EPSs). The cells within the biofilm produce the EPS components, which are typically a polymeric conglomeration of extracellular polysaccharides, proteins, lipids and DNA. Because they have three-dimensional structure and represent a community lifestyle for microorganisms, they have been metaphorically described as "cities for microbes". Biofilms may form on living or non-living surfaces and can be prevalent in natural, industrial, and hospital settings. They may constitute a microbiome or be a portion of it. The microbial cells growing in a biofilm are physiologically distinct from planktonic cells of the same organism, which, by contrast, are single cells that may float or swim in a liquid medium. Biofilms can form ...
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