Richard Lavenham Gardner
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Richard Lavenham Gardner
Sir Richard Lavenham Gardner, FRSB, FRS (born 10 June 1943) is a British embryologist and geneticist. He is currently an Emeritus Professor at the University of York, and was previously a Royal Society Research Professor. Since 1982 he has been Chair of the Royal Society Working Group on human embryo research, stem cells and cloning. He was the President of the Institute of Biology from 2006 to 2008, President of the Institute of Animal Biotechnology from 1986 to 2006 and is currently Chair of Trustees of the Animals in Science – Education Trust. Early life and education Gardner was born in Dorking, Surrey. His father, a professional artist specialising in stained glass, was killed a few weeks later during the landings on Sicily. Gardner was educated at St John's School, Leatherhead and later studied Natural Sciences at St Catharine's College, Cambridge before doing a PhD in the University's Physiology Department with Nobel Laureate, Robert Edwards. In 1973 he was appointe ...
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Fellow Of The Royal Society Of Biology
Fellowship of the Royal Society of Biology (FRSB), previously Fellowship of the Society of Biology (FSB), is an award and fellowship granted to individuals that the Royal Society of Biology has adjudged to have made a "prominent contribution to the advancement of the biological sciences, and has gained no less than five years of experience in a position of senior responsibility". Fellowship Fellows are entitled to use the post-nominal letters FRSB. examples of fellows include David Attenborough, Martin Hume Johnson, Jasmin Fisher and Nancy Rothwell Dame Nancy Jane Rothwell (born 2 October 1955) is a British physiologist. She has served as president and vice-chancellor of the University of Manchester since July 2010, having served as Deputy President and Deputy Vice-Chancellor until Januar .... See the : Fellows of the Royal Society of Biology for more examples. References {{Reflist Royal Society of Biology Academic awards * ...
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Blastocyst
The blastocyst is a structure formed in the early embryonic development of mammals. It possesses an inner cell mass (ICM) also known as the ''embryoblast'' which subsequently forms the embryo, and an outer layer of trophoblast cells called the trophectoderm. This layer surrounds the inner cell mass and a fluid-filled cavity known as the blastocoel. In the late blastocyst the trophectoderm is known as the trophoblast. The trophoblast gives rise to the chorion and amnion, the two fetal membranes that surround the embryo. The placenta derives from the embryonic chorion (the portion of the chorion that develops villi) and the underlying uterine tissue of the mother. The name "blastocyst" arises from the Greek ' ("a sprout") and ' ("bladder, capsule"). In other animals this is a structure consisting of an undifferentiated ball of cells and is called a blastula. In humans, blastocyst formation begins about five days after fertilization when a fluid-filled cavity opens up in the mor ...
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Royal Medal
The Royal Medal, also known as The Queen's Medal and The King's Medal (depending on the gender of the monarch at the time of the award), is a silver-gilt medal, of which three are awarded each year by the Royal Society, two for "the most important contributions to the advancement of natural knowledge" and one for "distinguished contributions in the applied sciences", done within the Commonwealth of Nations. Background The award was created by George IV of the United Kingdom, George IV and awarded first during 1826. Initially there were two medals awarded, both for the most important discovery within the year previous, a time period which was lengthened to five years and then shortened to three. The format was endorsed by William IV of the United Kingdom, William IV and Victoria of the United Kingdom, Victoria, who had the conditions changed during 1837 so that mathematics was a subject for which a Royal Medal could be awarded, albeit only every third year. The conditions were chang ...
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March Of Dimes Prize In Developmental Biology
The March of Dimes Prize in Developmental Biology is awarded once a year by the March of Dimes. It carries a $250,000 award "to an investigator whose research brings us closer to the day when all babies will be born healthy." It also includes a medal in the shape of a Roosevelt (who founded the March of Dimes) dime. Laureates SourceMarch of Dimes* 2020 Susan Fisher * 2019 Myriam Hemberger * 2018 Allan C. Spradling * 2017 Charles David Allis * 2016 Victor R. Ambros and Gary B. Ruvkun * 2015 Rudolf Jaenisch * 2014 Huda Y. Zoghbi * 2013 Eric N. Olson * 2012 Elaine Fuchs and Howard Green * 2011 Patricia Ann Jacobs and David C. Page * 2010 Shinya Yamanaka * 2009 Kevin P. Campbell and Louis M. Kunkel * 2008 Philip A. Beachy and Clifford Tabin * 2007 Anne McLaren and Janet Rossant * 2006 Alexander Varshavsky * 2005 Mario R. Capecchi and Oliver Smithies * 2004 Mary F. Lyon Mary Frances Lyon (15 May 1925 – 25 December 2014) was an English geneticist best known for her di ...
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Fellow Of The Royal Society
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, including mathematics, engineering science, and medical science". Fellow, Fellowship of the Society, the oldest known scientific academy in continuous existence, is a significant honour. It has been awarded to many eminent scientists throughout history, including Isaac Newton (1672), Michael Faraday (1824), Charles Darwin (1839), Ernest Rutherford (1903), Srinivasa Ramanujan (1918), Albert Einstein (1921), Paul Dirac (1930), Winston Churchill (1941), Subrahmanyan Chandrasekhar (1944), Dorothy Hodgkin (1947), Alan Turing (1951), Lise Meitner (1955) and Francis Crick (1959). More recently, fellowship has been awarded to Stephen Hawking (1974), David Attenborough (1983), Tim Hunt (1991), Elizabeth Blackburn (1992), Tim Berners-Lee (2001), Venki R ...
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Zoological Society Of London
The Zoological Society of London (ZSL) is a charity devoted to the worldwide conservation of animals and their habitats. It was founded in 1826. Since 1828, it has maintained the London Zoo, and since 1931 Whipsnade Park. History On 29 November 1822, the birthday of John Ray, "the father of modern zoology", a meeting held in the Linnean Society in Soho Square led by Rev. William Kirby, resolved to form a "Zoological Club of the Linnean Society of London". Between 1816 and 1826, discussions between Stamford Raffles, Humphry Davy, Joseph Banks and others led to the idea that London should have an establishment similar to the Jardin des Plantes in Paris. It would house a zoological collection "which should interest and amuse the public." The society was founded in April 1826 by Sir Stamford Raffles, the Marquess of Lansdowne, Lord Auckland, Sir Humphry Davy, Robert Peel, Joseph Sabine, Nicholas Aylward Vigors along with various other nobility, clergy, and naturalists. ...
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Patrick Steptoe
Patrick Christopher Steptoe CBE FRS (9 June 1913 – 21 March 1988) was an English obstetrician and gynaecologist and a pioneer of fertility treatment. Steptoe was responsible with biologist and physiologist Robert Edwards and the nurse Jean Purdy for developing in vitro fertilisation. Louise Joy Brown, the first test-tube baby, was born on 25 July 1978. Edwards was awarded the 2010 Nobel Prize in Physiology or Medicine for his work on the development of in vitro fertilisation; Steptoe and Purdy were not eligible for consideration because the Nobel Prize is not awarded posthumously. Education Born in Oxford, Steptoe was educated at The Grammar School, Witney (since 1968 the comprehensive Henry Box School) in Oxfordshire. He went to King's College London and graduated from St George's Hospital Medical School, London in 1939. He served in the Royal Navy from 1939–1946 and attained the rank of Lieutenant Commander. From 1947 to 1949 he was chief assistant in obstetrics and ...
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Royal Society Of Biology
The Royal Society of Biology (RSB), previously called the Society of Biology, is a learned society and professional association in the United Kingdom created to advance the interests of biology in academia, industry, education, and research. Formed in 2009 by the merger of the Biosciences Federation and the Institute of Biology, the society has around 18,000 individual members, and more than 100 member organisations. In addition to engaging the public on matters related to the life sciences, the society seeks to develop the profession and to guide the development of related policies. Organisation In May 2015, the society, previously called the Society of Biology, was granted permission to become the "Royal Society of Biology". The society is also a registered charity. The first president of the society was Nancy Rothwell (University of Manchester); the current president is Julia Goodfellow. The society has six Special Interest Groups: the Animal Science Group, UK Biology Comp ...
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Preimplantation Genetic Diagnosis
Preimplantation genetic diagnosis (PGD or PIGD) is the genetic profiling of embryos prior to implantation (as a form of embryo profiling), and sometimes even of oocytes prior to fertilization. PGD is considered in a similar fashion to prenatal diagnosis. When used to screen for a specific genetic disease, its main advantage is that it avoids selective abortion, as the method makes it highly likely that the baby will be free of the disease under consideration. PGD thus is an adjunct to assisted reproductive technology, and requires in vitro fertilization (IVF) to obtain oocytes or embryos for evaluation. Embryos are generally obtained through blastomere or blastocyst biopsy. The latter technique has proved to be less deleterious for the embryo, therefore it is advisable to perform the biopsy around day 5 or 6 of development. The world's first PGD was performed by Handyside, Kontogianni and Winston at the Hammersmith Hospital in London. Female embryos were selectively transferred ...
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Genetic Modification
Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA is obtained by either isolating and copying the genetic material of interest using recombinant DNA methods or by artificially synthesising the DNA. A construct is usually created and used to insert this DNA into the host organism. The first recombinant DNA molecule was made by Paul Berg in 1972 by combining DNA from the monkey virus SV40 with the lambda virus. As well as inserting genes, the process can be used to remove, or "knock out", genes. The new DNA can be inserted randomly, or targeted to a specific part of the genome. An organism that is generated through genetic engineering is considered to be genetically modified (GM) an ...
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Embryonic Stem Cell
Embryonic stem cells (ESCs) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre- implantation embryo. Human embryos reach the blastocyst stage 4–5 days post fertilization, at which time they consist of 50–150 cells. Isolating the inner cell mass (embryoblast) using immunosurgery results in destruction of the blastocyst, a process which raises ethical issues, including whether or not embryos at the pre-implantation stage have the same moral considerations as embryos in the post-implantation stage of development. Researchers are currently focusing heavily on the therapeutic potential of embryonic stem cells, with clinical use being the goal for many laboratories. Potential uses include the treatment of diabetes and heart disease. The cells are being studied to be used as clinical therapies, models of genetic disorders, and cellular/DNA repair. However, adverse effects in the research and clinical processes such as tumors and unw ...
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Germline
In biology and genetics, the germline is the population of a multicellular organism's cells that pass on their genetic material to the progeny (offspring). In other words, they are the cells that form the egg, sperm and the fertilised egg. They are usually differentiated to perform this function and segregated in a specific place away from other bodily cells. As a rule, this passing-on happens via a process of sexual reproduction; typically it is a process that includes systematic changes to the genetic material, changes that arise during recombination, meiosis and fertilization for example. However, there are many exceptions across multicellular organisms, including processes and concepts such as various forms of apomixis, autogamy, automixis, cloning or parthenogenesis. The cells of the germline are called germ cells. For example, gametes such as a sperm and an egg are germ cells. So are the cells that divide to produce gametes, called gametocytes, the cells that produce thos ...
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