Ribonuclease T2
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Ribonuclease T2
Ribonuclease T2 (, ''ribonuclease II'', ''base-non-specific ribonuclease'', ''nonbase-specific RNase'', ''RNase (non-base specific)'', ''non-base specific ribonuclease'', ''nonspecific RNase'', ''RNase Ms'', ''RNase M'', ''RNase II'', ''Escherichia coli ribonuclease II'', ''ribonucleate nucleotido-2'-transferase (cyclizing)'', ''acid ribonuclease'', ''RNAase CL'', ''Escherichia coli ribonuclease I' ribonuclease PP2'', ''ribonuclease N2'', ''ribonuclease M'', ''acid RNase'', ''ribonnuclease (non-base specific)'', ''ribonuclease (non-base specific)'', ''RNase T2'', ''ribonuclease PP3'', ''ribonucleate 3'-oligonucleotide hydrolase'', ''ribonuclease U4'') is an enzyme. It is a type of endoribonuclease. This enzyme catalyses the following chemical reaction : Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates See also *RNASET2 Ribonuclease T2 is an enzyme that in humans is encoded by the ''RNASET2 ...
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Enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the reaction ra ...
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Endoribonuclease
An endoribonuclease is a ribonuclease endonuclease. It cleaves either single-stranded or double-stranded RNA, depending on the enzyme. Example includes both single proteins such as RNase III, RNase A, RNase T1, RNase T2 and RNase H and also complexes of proteins with RNA such as RNase P and the RNA-induced silencing complex. Further examples include endoribonuclease XendoU found in frogs (''Xenopus ''Xenopus'' () (Gk., ξενος, ''xenos''=strange, πους, ''pous''=foot, commonly known as the clawed frog) is a genus of highly aquatic frogs native to sub-Saharan Africa. Twenty species are currently described within it. The two best-known ...''). External links * {{Nucleases EC 3.1 Ribonucleases ...
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Catalysis
Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycles quickly, very small amounts of catalyst often suffice; mixing, surface area, and temperature are important factors in reaction rate. Catalysts generally react with one or more reactants to form intermediates that subsequently give the final reaction product, in the process of regenerating the catalyst. Catalysis may be classified as either homogeneous, whose components are dispersed in the same phase (usually gaseous or liquid) as the reactant, or heterogeneous, whose components are not in the same phase. Enzymes and other biocatalysts are often considered as a third category. Catalysis is ubiquitous in chemical industry of all kinds. Estimates are that 90% of all commercially produced chemical products involve catalysts at some s ...
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Chemical Reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and breaking of chemical bonds between atoms, with no change to the Atomic nucleus, nuclei (no change to the elements present), and can often be described by a chemical equation. Nuclear chemistry is a sub-discipline of chemistry that involves the chemical reactions of unstable and radioactive Chemical element, elements where both electronic and nuclear changes can occur. The substance (or substances) initially involved in a chemical reaction are called reagent, reactants or reagents. Chemical reactions are usually characterized by a chemical change, and they yield one or more Product (chemistry), products, which usually have properties different from the reactants. Reactions often consist of a sequence o ...
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RNASET2
Ribonuclease T2 is an enzyme that in humans is encoded by the ''RNASET2'' gene. It is a type of endoribonuclease An endoribonuclease is a ribonuclease endonuclease. It cleaves either single-stranded or double-stranded RNA, depending on the enzyme. Example includes both single proteins such as RNase III, RNase A, RNase T1, RNase T2 and RNase H and also complex .... This ribonuclease gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. RNASET2 has been reported as a tumour associated antigen in anaplastic large cell lymphoma and other lymphomas. References Further reading

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