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RepliCel
RepliCel Life Sciences is a Canadian regenerative medicine company based in Vancouver, British Columbia. The company focuses on development of cell therapies using a patient's own cells (autologous cell therapy). The company has treatment development activities targeting chronic tendon injuries which have failed to heal properly, and hair restoration. The company's expertise lies in isolation and exploitation of different cell populations found in the human hair follicle. The company's business model is focused on establishing proof-of-concept Proof of concept (POC or PoC), also known as proof of principle, is a realization of a certain method or idea in order to demonstrate its feasibility, or a demonstration in principle with the aim of verifying that some concept or theory has prac ... for treatments leading to acquisition by a larger company. An alternative business model has been reported which does not involve acquisition but rather partnership where technologies and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vancouver
Vancouver ( ) is a major city in western Canada, located in the Lower Mainland region of British Columbia. As the List of cities in British Columbia, most populous city in the province, the 2021 Canadian census recorded 662,248 people in the city, up from 631,486 in 2016. The Greater Vancouver, Greater Vancouver area had a population of 2.6million in 2021, making it the List of census metropolitan areas and agglomerations in Canada#List, third-largest metropolitan area in Canada. Greater Vancouver, along with the Fraser Valley Regional District, Fraser Valley, comprises the Lower Mainland with a regional population of over 3 million. Vancouver has the highest population density in Canada, with over 5,700 people per square kilometre, and fourth highest in North America (after New York City, San Francisco, and Mexico City). Vancouver is one of the most Ethnic origins of people in Canada, ethnically and Languages of Canada, linguistically diverse cities in Canada: 49.3 percent of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chief Executive Officer
A chief executive officer (CEO), also known as a central executive officer (CEO), chief administrator officer (CAO) or just chief executive (CE), is one of a number of corporate executives charged with the management of an organization especially an independent legal entity such as a company or nonprofit institution. CEOs find roles in a range of organizations, including public and private corporations, non-profit organizations and even some government organizations (notably state-owned enterprises). The CEO of a corporation or company typically reports to the board of directors and is charged with maximizing the value of the business, which may include maximizing the share price, market share, revenues or another element. In the non-profit and government sector, CEOs typically aim at achieving outcomes related to the organization's mission, usually provided by legislation. CEOs are also frequently assigned the role of main manager of the organization and the highest-ranking offic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Full-time Equivalent
Full-time equivalent (FTE), or whole time equivalent (WTE), is a unit that indicates the workload of an employee, employed person (or student) in a way that makes workloads or class loads comparable across various contexts. FTE is often used to measure a worker's or student's involvement in a project, or to track cost reductions in an organization. An FTE of 1.0 is equivalent to a full-time worker or student, while an FTE of 0.5 signals half of a full work or school load. United States According to the Federal government of the United States, FTE is defined by the Government Accountability Office (GAO) as the number of total hours worked divided by the maximum number of compensable hours in a full-time schedule as defined by law. For example, if the normal schedule for a quarter is defined as 411.25 hours ([35 hours per week * (52 weeks per year – 5 weeks' regulatory vacation)] / 4), then someone working 100 hours during that quarter represents 100/411.25 = 0.24 FTE. Two employ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Regenerative Medicine
Regenerative medicine deals with the "process of replacing, engineering or regenerating human or animal cells, tissues or organs to restore or establish normal function". This field holds the promise of engineering damaged tissues and organs by stimulating the body's own repair mechanisms to functionally heal previously irreparable tissues or organs. Regenerative medicine also includes the possibility of growing tissues and organs in the laboratory and implanting them when the body cannot heal itself. When the cell source for a regenerated organ is derived from the patient's own tissue or cells, the challenge of organ transplant rejection via immunological mismatch is circumvented. This approach could alleviate the problem of the shortage of organs available for donation. Some of the biomedical approaches within the field of regenerative medicine may involve the use of stem cells. Examples include the injection of stem cells or progenitor cells obtained through directed differenti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Therapy
Cell therapy (also called cellular therapy, cell transplantation, or cytotherapy) is a therapy in which viable cells are injected, grafted or implanted into a patient in order to effectuate a medicinal effect, for example, by transplanting T-cells capable of fighting cancer cells via cell-mediated immunity in the course of immunotherapy, or grafting stem cells to regenerate diseased tissues. Cell therapy originated in the nineteenth century when scientists experimented by injecting animal material in an attempt to prevent and treat illness. Although such attempts produced no positive benefit, further research found in the mid twentieth century that human cells could be used to help prevent the human body rejecting transplanted organs, leading in time to successful bone marrow transplantation as has become common practice in treatment for patients that have compromised bone marrow after disease, infection, radiation or chemotherapy. In recent decades, however, stem cell and cel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Autologous
Autotransplantation is the transplantation of organs, tissues, or even particular proteins from one part of the body to another in the same person ('' auto-'' meaning "self" in Greek). The autologous tissue (also called autogenous, autogeneic, or autogenic tissue) transplanted by such a procedure is called an autograft or autotransplant. It is contrasted with allotransplantation (from other individual of the same species), syngeneic transplantation (grafts transplanted between two genetically identical individuals of the same species) and xenotransplantation (from other species). A common example is the removal of a piece of bone (usually from the hip) and its being ground into a paste for the reconstruction of another portion of bone. Autotransplantation, although most common with blood, bone, or skin, can be used for a wide variety of organs. One of the rare examples is autotransplantation of a kidney from one side of the body to the other. Kidney autotransplantation is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tendon
A tendon or sinew is a tough, high-tensile-strength band of dense fibrous connective tissue that connects muscle to bone. It is able to transmit the mechanical forces of muscle contraction to the skeletal system without sacrificing its ability to withstand significant amounts of tension. Tendons are similar to ligaments; both are made of collagen. Ligaments connect one bone to another, while tendons connect muscle to bone. Structure Histologically, tendons consist of dense regular connective tissue. The main cellular component of tendons are specialized fibroblasts called tendon cells (tenocytes). Tenocytes synthesize the extracellular matrix of tendons, abundant in densely packed collagen fibers. The collagen fibers are parallel to each other and organized into tendon fascicles. Individual fascicles are bound by the endotendineum, which is a delicate loose connective tissue containing thin collagen fibrils and elastic fibres. Groups of fascicles are bounded by the epitenon, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Regen
Regen ( Northern Bavarian: ''Reng'') is a town in Bavaria, Germany, and the district town of the district of Regen. Geography Regen is situated on the great Regen River, located in the Bavarian Forest. Divisions Originally the town consisted of 4 districts: Bürgerholz, Grubhügel, Riedham and St. Johann. After a governmental reform the villages of: * Aden * Augrub * Bärndorf * Bettmannsäge * Dreieck * Ebenhof * Ecklend * Edhof * Eggenried * Finkenried * Frauenmühle * Großseiboldsried * Huberhof * Kagerhof * Kattersdorf * Kerschlhöh * Kleinseiboldsried * Kreuzerhof * Kühhof * March * Maschenberg * Matzelsried * Metten * Neigerhöhe * Neigermühle * Neusohl * Obermitterdorf * Oberneumais * Oleumhütte * Pfistermühle * Pometsau * Poschetsried * Reinhartsmais * Richtplatz * Rinchnachmündt * Rohrbach * Sallitz * Schauerhof * Schlossau * Schochert * Schollenried * Schönhöh * Schützenhof * Schwaighof * Schweinhütt * Spitalhof ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hair Restoration
The management of hair loss, includes prevention and treatment of alopecia, baldness, and hair thinning, and regrowth of hair. Prevention Scratching of itchy scalp may contribute to hair loss. Health Body weight Prevention of obesity helps. Obesity is linked to hair thinning. Healthy diet Oils with fatty acids that has been studied to prevent dermatitis includes: * Corn oil: Linoleic acid (LA) * Fish oil: Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) * Hemp seed oil: Linoleic acid (LA), and alpha-Linolenic acid (ALA) Alternative medicine The scalp must be cleaned from sebum, sweat, and dirt, prior to topical application, for agents to penetrate it. A 2020 systemic review on agents used to treat androgenic alopecia found that: * Oral supplementation of vitamin A, B, C, D, E, and trace element iron, selenium, and zinc, will prevent androgenic alopecia caused by malnutrition. Multivitamins can be used. * Topical application of onion juice, rosemary oil, s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hair Follicle
The hair follicle is an organ found in mammalian skin. It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction between hormones, neuropeptides, and immune cells. This complex interaction induces the hair follicle to produce different types of hair as seen on different parts of the body. For example, terminal hairs grow on the scalp and lanugo hairs are seen covering the bodies of fetuses in the uterus and in some newborn babies. The process of hair growth occurs in distinct sequential stages. The first stage is called ''anagen'' and is the active growth phase, ''telogen'' is the resting stage, ''catagen'' is the regression of the hair follicle phase, ''exogen'' is the active shedding of hair phase and lastly ''kenogen'' is the phase between the empty hair follicle and the growth of new hair. The function of hair in humans has long been a subject of interest ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Business Model
A business model describes how an organization creates, delivers, and captures value,''Business Model Generation'', Alexander Osterwalder, Yves Pigneur, Alan Smith, and 470 practitioners from 45 countries, self-published, 2010 in economic, social, cultural or other contexts. The process of business model construction and modification is also called ''business model innovation'' and forms a part of business strategy. In theory and practice, the term ''business model'' is used for a broad range of informal and formal descriptions to represent core aspects of an organization or business, including purpose, business process, target customers, offerings, strategies, infrastructure, organizational structures, sourcing, trading practices, and operational processes and policies including culture. Context The literature has provided very diverse interpretations and definitions of a business model. A systematic review and analysis of manager responses to a survey defines business models ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
