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Rahul Desikan
Rahul Desikan (June 6, 1978 – July 14, 2019) was an Indian-American neuroscientist and neuroradiologist. He was an Assistant Professor of Radiology & Biomedical Imaging, Neurology and Pediatrics at the University of California, San Francisco, and co-director of Laboratory for Precision Neuroimaging. Desikan's achievements became publicly known in a ''Washington Post'' article detailing his lifelong commitment to preventing and treating Alzheimer's disease and his continuing work as a scientist living with Amyotrophic lateral sclerosis (ALS). Desikan was vocal about the need for increased awareness and research funding for ALS, and voiced his unique perspective as both ALS researcher and ALS patient in op-ed articles appearing in a regular column in the ''Washington Post'' as well as in the ''San Francisco Chronicle'' and ''Scientific American.'' Education and early influences Desikan graduated from The Bronx High School of Science, a school for gifted students, in 1995. Desik ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rahul Desikan MD PhD In His Lab 2018
Rahul is a popular male name in India and has a variety of meanings. The earliest meaning found in the Upanishads is "conqueror of all miseries." Later use of the word is attributed to the Buddha, who named his son ''Rahula'' as he felt that family ties could be an obstacle in the path to renunciation and nirvana. Buddha uttered Rahul when he first saw his son and gave a new meaning "relationship" and "bondage" to this name. Rahul means ''Moon, Able/efficient'' in Sanskrit and Pali. Rahul also means "Traveler" in Arabic. People named Rahul Personalities in the fields of Arts * Rahul Banerjee (actor) (born 1983), Indian Bengali actor * Rahul Bhatt (born 1982), Indian fitness trainer and actor * Rahul Bose (born 1967), Indian Bengali actor, director, screenwriter, social activist * Rahul Deshpande (born 1979), Indian classical singer * Rahul Dev (born 1968), Indian actor and model * Rahul Dev Burman (1939–1994), Indian composer and music director * Rahul Dholakia, Indian fil ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anders Dale
Anders Martin Dale is a prominent neuroscientist and professor of radiology, neurosciences, psychiatry, and cognitive science at the University of California, San Diego (UCSD), and is one of the world's leading developers of sophisticated computational neuroimaging techniques. He is the founding Director of the Center for Multimodal Imaging Genetics (CMIG) at UCSD. Dale founded and initially developed the brain imaging analysis software FreeSurfer as a graduate student at UCSD. He later co-developed FreeSurfer at Massachusetts General Hospital/Harvard Medical School with Bruce Fischl. In addition to FreeSurfer, his major scientific contributions include developing: a) event related functional magnetic resonance imaging (fMRI) (with Randy Buckner at Harvard), b) an in vivo method to quantify the gray matter thickness of the cerebral cortex using MRI images (with Bruce Fischl at Harvard), c) an analysis platform to combine fMRI with magnetoencephalography (MEG), d) computational mo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurodegeneration
A neurodegenerative disease is caused by the progressive loss of structure or function of neurons, in the process known as neurodegeneration. Such neuronal damage may ultimately involve cell death. Neurodegenerative diseases include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, and prion diseases. Neurodegeneration can be found in the brain at many different levels of neuronal circuitry, ranging from molecular to systemic. Because there is no known way to reverse the progressive degeneration of neurons, these diseases are considered to be incurable; however research has shown that the two major contributing factors to neurodegeneration are oxidative stress and inflammation. Biomedical research has revealed many similarities between these diseases at the subcellular level, including atypical protein assemblies (like proteinopathy) and induced cell death. These similarities suggest that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biomarker
In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues to examine normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. as cited in Biomarkers are used in many scientific fields. Medicine Biomarkers used in the medical field, are a part of a relatively new clinical toolset categorized by their clinical applications. The three main classes are molecular biomarkers, cellular biomarkers or imaging biomarkers. All three types of biomarkers have a clinical role in narrowing or guiding treatment decisions and follow a sub-categorization of being either predictive, prognostic, or diagnostic. Predictive Predictive molecular, cellular, or imaging biomarkers that pass validation can serve as a method of predicting clinical outcomes. Predictive biomarkers are used to help optimize id ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FreeSurfer
FreeSurfer is a brain imaging software package originally developed by Bruce Fischl, Anders Dale, Martin Sereno, and Doug Greve. Development and maintenance of FreeSurfer is now the primary responsibility of the Laboratory for Computational Neuroimaging at the Athinoula A. Martinos Center for Biomedical Imaging. FreeSurfer contains a set of programs with a common focus of analyzing magnetic resonance imaging (MRI) scans of brain tissue. It is an important tool in functional brain mapping and contains tools to conduct both volume based and surface based analysis. FreeSurfer includes tools for the reconstruction of topologically correct and geometrically accurate models of both the gray/white and pial surfaces, for measuring cortical thickness, surface area and folding, and for computing inter-subject registration based on the pattern of cortical folds. 57,541 copies of the FreeSurfer software package have been registered for use as of April 2022 and it is a core tool in the proc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cerebral Cortex
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of allocortex. It is separated into two cortices, by the longitudinal fissure that divides the cerebrum into the left and right cerebral hemispheres. The two hemispheres are joined beneath the cortex by the corpus callosum. The cerebral cortex is the largest site of neural integration in the central nervous system. It plays a key role in attention, perception, awareness, thought, memory, language, and consciousness. The cerebral cortex is part of the brain responsible for cognition. In most mammals, apart from small mammals that have small brains, the cerebral cortex is folded, providing a greater surface area in the confined volume of the cranium. Apart from minimising brain and cranial volume, cortical folding is crucial for the brain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurodegeneration
A neurodegenerative disease is caused by the progressive loss of structure or function of neurons, in the process known as neurodegeneration. Such neuronal damage may ultimately involve cell death. Neurodegenerative diseases include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, and prion diseases. Neurodegeneration can be found in the brain at many different levels of neuronal circuitry, ranging from molecular to systemic. Because there is no known way to reverse the progressive degeneration of neurons, these diseases are considered to be incurable; however research has shown that the two major contributing factors to neurodegeneration are oxidative stress and inflammation. Biomedical research has revealed many similarities between these diseases at the subcellular level, including atypical protein assemblies (like proteinopathy) and induced cell death. These similarities suggest that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polygenic Hazard Score
A polygene is a member of a group of non- epistatic genes that interact additively to influence a phenotypic trait, thus contributing to multiple-gene inheritance (polygenic inheritance, multigenic inheritance, quantitative inheritance), a type of non-Mendelian inheritance, as opposed to single-gene inheritance, which is the core notion of Mendelian inheritance. The term "monozygous" is usually used to refer to a hypothetical gene as it is often difficult to distinguish the effect of an individual gene from the effects of other genes and the environment on a particular phenotype. Advances in statistical methodology and high throughput sequencing are, however, allowing researchers to locate candidate genes for the trait. In the case that such a gene is identified, it is referred to as a quantitative trait locus (QTL). These genes are generally pleiotropic as well. The genes that contribute to type 2 diabetes are thought to be mostly polygenes. In July 2016, scientists reported ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jt Rh Pial Freesurfer Tksurfer2
JT may refer to: Arts and media * '' Jakobstads Tidning'', a Finland-Swedish newspaper * Jimma Times, owner of the Ethiopian newspaper ''Yeroo'' * '' Jornal da Tarde'', a Brazilian newspaper from São Paulo * ''JT'' (album), 1977 album by James Taylor * ''J.T.'' (album), 2021 album by Steve Earle & The Dukes * J.T. Lambert, a character in the American television sitcom '' Step by Step'' * J.T. Martin, a character in the TV sitcom '' Silver Spoons'' * JT LeRoy, a literary persona created in the 1990s by American writer Laura Albert * J.T. Yorke, a character in ''Degrassi: The Next Generation'' Businesses and organizations * Japan Tobacco, a cigarette manufacturer * Jersey Telecom, the Jersey telephone company * JT, the IATA airline designator for Lion Air People In arts and entertainment * James "J.T." Taylor (born 1953), lead singer of the band Kool and the Gang * JT the Bigga Figga (born 1971), a hip-hop artist and producer * J. T. the Brick (born 1965), an American ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brain Diseases
Central nervous system diseases, also known as central nervous system disorders, are a group of neurological disorders that affect the structure or function of the brain or spinal cord, which collectively form the central nervous system (CNS). These disorders may be caused by such things as infection, injury, blood clots, age related degeneration, cancer, autoimmune disfunction, and birth defects. The symptoms vary widely, as do the treatments. Central nervous system tumors are the most common forms of pediatric cancer. Brain tumors are the most frequent and have the highest mortality. Some disorders, such as substance addiction, autism, and ADHD may be regarded as CNS disorders, though the classifications are not without dispute. Signs and symptoms Every disease has different signs and symptoms. Some of them are persistent headache; pain in the face, back, arms, or legs; an inability to concentrate; loss of feeling; memory loss; loss of muscle strength; tremors; seizures; incr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Big Data
Though used sometimes loosely partly because of a lack of formal definition, the interpretation that seems to best describe Big data is the one associated with large body of information that we could not comprehend when used only in smaller amounts. In it primary definition though, Big data refers to data sets that are too large or complex to be dealt with by traditional data-processing application software. Data with many fields (rows) offer greater statistical power, while data with higher complexity (more attributes or columns) may lead to a higher false discovery rate. Big data analysis challenges include capturing data, data storage, data analysis, search, sharing, transfer, visualization, querying, updating, information privacy, and data source. Big data was originally associated with three key concepts: ''volume'', ''variety'', and ''velocity''. The analysis of big data presents challenges in sampling, and thus previously allowing for only observations and sampling. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
