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RVSV-ZEBOV Vaccine
Recombinant vesicular stomatitis virus–Zaire Ebola virus (rVSV-ZEBOV), also known as Ebola Zaire vaccine live and sold under the brand name Ervebo, is an Ebola vaccine for adults that prevents Ebola caused by the Zaire ebolavirus. When used in ring vaccination, rVSV-ZEBOV has shown a high level of protection. Around half the people given the vaccine have mild to moderate adverse effects that include headache, fatigue, and muscle pain. rVSV-ZEBOV is a recombinant, replication-competent viral vector vaccine. It consists of rice-derived recombinant human serum albumin and live attenuated recombinant vesicular stomatitis virus (VSV), which has been genetically engineered to express the main glycoprotein from the Zaire ebolavirus so as to provoke a neutralizing immune response to the Ebola virus. The vaccine was approved for medical use in the European Union and the United States in 2019. It was created by scientists at the National Microbiology Laboratory in Winnipeg, M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electron Micrograph
A micrograph or photomicrograph is a photograph or digital image taken through a microscope or similar device to show a magnified image of an object. This is opposed to a macrograph or photomacrograph, an image which is also taken on a microscope but is only slightly magnified, usually less than 10 times. Micrography is the practice or art of using microscopes to make photographs. A micrograph contains extensive details of microstructure. A wealth of information can be obtained from a simple micrograph like behavior of the material under different conditions, the phases found in the system, failure analysis, grain size estimation, elemental analysis and so on. Micrographs are widely used in all fields of microscopy. Types Photomicrograph A light micrograph or photomicrograph is a micrograph prepared using an optical microscope, a process referred to as ''photomicroscopy''. At a basic level, photomicroscopy may be performed simply by connecting a camera to a microscope, t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Merck & Co
Merck & Co., Inc. is an American multinational pharmaceutical company headquartered in Rahway, New Jersey, and is named for Merck Group, founded in Germany in 1668, of whom it was once the American arm. The company does business as Merck Sharp & Dohme or MSD outside the United States and Canada. Merck & Co. was originally established as the American affiliate of Merck Group in 1891. Merck develops and produces medicines, vaccines, biologic therapies and animal health products. It has multiple blockbuster drugs or products each with 2020 revenues including cancer immunotherapy, anti-diabetic medication and vaccines against HPV and chickenpox. The company is ranked 71st on the 2022 ''Fortune'' 500 and 87th on the 2022 ''Forbes'' Global 2000, both based on 2021 revenues. Products The company develops medicines, vaccines, biologic therapies and animal health products. In 2020, the company had 6 blockbuster drugs or products, each with over $1 billion in revenue: ''Keytruda' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2014 Ebola Virus Epidemic In West Africa Simplified
Fourteen or 14 may refer to: * 14 (number), the natural number following 13 and preceding 15 * one of the years 14 BC, AD 14, 1914, 2014 Music * 14th (band), a British electronic music duo * ''14'' (David Garrett album), 2013 *''14'', an unreleased album by Charli XCX * "14" (song), 2007, from ''Courage'' by Paula Cole Other uses * ''Fourteen'' (film), a 2019 American film directed by Dan Sallitt * ''Fourteen'' (play), a 1919 play by Alice Gerstenberg * ''Fourteen'' (manga), a 1990 manga series by Kazuo Umezu * ''14'' (novel), a 2013 science fiction novel by Peter Clines * ''The 14'', a 1973 British drama film directed by David Hemmings * Fourteen, West Virginia, United States, an unincorporated community * Lot Fourteen, redevelopment site in Adelaide, South Australia, previously occupied by the Royal Adelaide Hospital * "The Fourteen", a nickname for NASA Astronaut Group 3 * Fourteen Words, a phrase used by white supremacists and Nazis See also * 1/4 (other) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rotavirus
''Rotavirus'' is a genus of double-stranded RNA viruses in the family ''Reoviridae''. Rotaviruses are the most common cause of diarrhoeal disease among infants and young children. Nearly every child in the world is infected with a rotavirus at least once by the age of five. Immunity develops with each infection, so subsequent infections are less severe. Adults are rarely affected. There are nine species of the genus, referred to as A, B, C, D, F, G, H, I and J. ''Rotavirus A'', the most common species, causes more than 90% of rotavirus infections in humans. The virus is transmitted by the faecal-oral route. It infects and damages the cells that line the small intestine and causes gastroenteritis (which is often called "stomach flu" despite having no relation to influenza). Although rotavirus was discovered in 1973 by Ruth Bishop and her colleagues by electron micrograph images and accounts for approximately one third of hospitalisations for severe diarrhoea in infants an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RotaTeq
Rotavirus vaccine is a vaccine used to protect against rotavirus infections, which are the leading cause of severe diarrhea among young children. The vaccines prevent 15–34% of severe diarrhea in the developing world and 37–96% of severe the risk of death among young children due to diarrhea. Immunizing babies decreases rates of disease among older people and those who have not been immunized. The World Health Organization (WHO) recommends that rotavirus vaccine be included in national routine vaccinations programs, especially in areas where the disease is common. This should be done along with promoting breastfeeding, handwashing, clean water, and good sanitation. It is given by mouth and requires two or three doses. It should be given starting around six weeks of age. The vaccines are safe. This includes their use in people with HIV/AIDS. The vaccines are made from weakened rotavirus. The vaccine first became available in the United States in 2006. It is on the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vero Cell
Vero cells are a lineage of cells used in cell cultures. The 'Vero' lineage was isolated from kidney epithelial cells extracted from an African green monkey (''Chlorocebus'' sp.; formerly called ''Cercopithecus aethiops'', this group of monkeys has been split into several different species). The lineage was developed on 27 March 1962, by Yasumura and Kawakita at the Chiba University in Chiba, Japan. The original cell line was named '' Vero'' after an abbreviation of , which means 'green kidney' in Esperanto, while itself means 'truth' in Esperanto. Characteristics The Vero cell lineage is continuous and aneuploid, meaning that it has an abnormal number of chromosomes. A continuous cell lineage can be replicated through many cycles of division and not become senescent. Vero cells are interferon-deficient; unlike normal mammalian cells, they do not secrete interferon alpha or beta when infected by viruses. However, they still have the Interferon-alpha/beta receptor, so they ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kikwit
Kikwit is the largest city of Kwilu Province, lying on the Kwilu River in the southwestern part of the Democratic Republic of the Congo. Kikwit is also known in the region under the nickname "The Mother". The population is approximately 458,000 (2017). An important commercial centre, it is home to a stadium and is known for its traditional dances, in particular the Bapende dancers whose geographic origin centers on the village of Gungu. Bapende dancers often wear traditional costumes comprising colorful masks and attire made from raffia. Kikwit is also home to an airport (Kikwit Airport) and is connected to the capital Kinshasa by a new road and river transport. In 1995 the city saw a serious outbreak of the deadly Ebola virus. Singer King Kester Emeneya was born in Kikwit in 1956. In April 2014, a tribute concert held in Kikwit to honor King Kester Emeneya ended in disaster, and at least thirteen people in the stadium died in a stampede following a power failure. See also ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
EBOV
''Zaire ebolavirus'', more commonly known as Ebola virus (; EBOV), is one of six known species within the genus '' Ebolavirus''. Four of the six known ebolaviruses, including EBOV, cause a severe and often fatal hemorrhagic fever in humans and other mammals, known as Ebola virus disease (EVD). Ebola virus has caused the majority of human deaths from EVD, and was the cause of the 2013–2016 epidemic in western Africa, which resulted in at least suspected cases and confirmed deaths. Ebola virus and its genus were both originally named for Zaire (now the Democratic Republic of the Congo), the country where it was first described, and was at first suspected to be a new "strain" of the closely related Marburg virus. The virus was renamed "Ebola virus" in 2010 to avoid confusion. Ebola virus is the single member of the species ''Zaire ebolavirus'', which is assigned to the genus '' Ebolavirus'', family '' Filoviridae'', order '' Mononegavirales''. The members of the species are ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RVSV-ZEBOV-GP
Recombinant vesicular stomatitis virus–Zaire Ebola virus (rVSV-ZEBOV), also known as Ebola Zaire vaccine live and sold under the brand name Ervebo, is an Ebola vaccine for adults that prevents Ebola caused by the Zaire ebolavirus. When used in ring vaccination, rVSV-ZEBOV has shown a high level of protection. Around half the people given the vaccine have mild to moderate adverse effects that include headache, fatigue, and muscle pain. rVSV-ZEBOV is a recombinant, replication-competent viral vector vaccine. It consists of rice-derived recombinant human serum albumin and live attenuated recombinant vesicular stomatitis virus (VSV), which has been genetically engineered to express the main glycoprotein from the Zaire ebolavirus so as to provoke a neutralizing immune response to the Ebola virus. The vaccine was approved for medical use in the European Union and the United States in 2019. It was created by scientists at the National Microbiology Laboratory in Winnipeg, M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Institut National Pour La Recherche Biomedicale
The Institut National de la Recherche Biomédicale (INRB) is the national medical research organization of the Democratic Republic of the Congo. The responsible ministry is the Ministry of Scientific Research and Technology. The National Biomedical Research Institute (INRB) was founded in 1984, it is a 70,000 m² establishment. It has been a collaborating center of the World Health Organization since 2018, headed by Professor Jean-Jacques Muyembe-Tamfum, MD, Ph., Which serves as a national biomedical research laboratory for the Ministry of Health of the Democratic Republic of Congo (DRC) ). It is a multidisciplinary institute which collectively has hundreds of years of experience both in the identification, treatment and prevention of diseases in the DRC. Its foundations are the performance of medical and biological analyzes, applied and translational research, the surveillance of communicable diseases and the promotion of professional growth and development. The INRB has continuo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2017 Democratic Republic Of The Congo Ebola Virus Outbreak
The Democratic Republic of the Congo (DRC) was identified by the World Health Organization (WHO) on 11 May 2017 as having one Ebola-related death. As of 8 June 2017, there were five confirmed cases and three probable cases. Of these, four survived and four died. The affected areas of the DRC are Mabongo (one confirmed), Ngayi (one probable), and Nambwa (four confirmed and two probable) in Likati health zone. According to the WHO, "Modelling suggests the risk of further cases is currently low but not negligible.... As of ... June 83% of simulated scenarios predict no further cases in the next 30 days." According to the U.S. Centers for Disease Control and Prevention, "Ebola ... is a rare and deadly disease caused by infection with one of the Ebola virus species. Ebola can cause disease in humans and nonhuman primates (monkeys, gorillas, and chimpanzees)." Ebola was first identified in 1976 near the Ebola River in the DRC. More than 11,300 people died in the 2013 to 2016 E ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care cov ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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