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RA Capital
RA Capital Management (RA Capital) is an American investment firm based in Boston. It is focused on making public and private investments in the Healthcare and Biotechnology industries. Background RA Capital was founded in January 2002 by Richard Aldrich and Peter Kolchinsky. Aldrich was the chief business officer Vertex Pharmaceuticals who left to set up his own company. He invited Kolchinsky, a PhD student at Harvard University to join him due his technical expertise. The firm's name comes from the initials of Richard Aldrich. The firm was initially set up as hedge fund that invested in public companies although it would later invest in private companies as well. RA Capital has an in-house research group, named TechAtlas that creates its disease-specific maps. One of the firm's earliest successful investments was its investment into Triangle Pharmaceuticals which Gilead Sciences acquired for $464 million in early 2003. Aldrich left RA Capital in 2009 to start L ...
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Berkeley Building
The Berkeley Building (also known as the Old John Hancock Building) is a 26-story, building located at 200 Berkeley Street, Boston, Massachusetts, USA. It is the second of the three John Hancock buildings built in Boston; it was succeeded by the John Hancock Tower. The building is known for the weather beacon at its summit, which displays distinctive light patterns as weather forecasts. The Berkeley Building is the 20th-tallest building in the city. History The building, located in Boston's Back Bay, was designed by Cram and Ferguson and completed in 1947. From 1947 until 1964 it was the second-tallest building in the city, one foot (30 cm) shorter than the Custom House Tower, but a much larger building and a conspicuous landmark. The Prudential Tower, completed in 1964, dwarfed both. , 17 buildings are taller, yet it remains an easily recognized Boston landmark, familiar to commuters crossing the Charles River. A drawing of this building served as a logo for the John H ...
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Venture Capital
Venture capital (often abbreviated as VC) is a form of private equity financing that is provided by venture capital firms or funds to startups, early-stage, and emerging companies that have been deemed to have high growth potential or which have demonstrated high growth (in terms of number of employees, annual revenue, scale of operations, etc). Venture capital firms or funds invest in these early-stage companies in exchange for equity, or an ownership stake. Venture capitalists take on the risk of financing risky start-ups in the hopes that some of the firms they support will become successful. Because startups face high uncertainty, VC investments have high rates of failure. The start-ups are usually based on an innovative technology or business model and they are usually from high technology industries, such as information technology (IT), clean technology or biotechnology. The typical venture capital investment occurs after an initial "seed funding" round. The first ro ...
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Hedge Fund Firms In Boston
A hedge or hedgerow is a line of closely spaced shrubs and sometimes trees, planted and trained to form a barrier or to mark the boundary of an area, such as between neighbouring properties. Hedges that are used to separate a road from adjoining fields or one field from another, and are of sufficient age to incorporate larger trees, are known as hedgerows. Often they serve as windbreaks to improve conditions for the adjacent crops, as in bocage country. When clipped and maintained, hedges are also a simple form of topiary. A hedge often operates as, and sometimes is called, a "live fence". This may either consist of individual fence posts connected with wire or other fencing material, or it may be in the form of densely planted hedges without interconnecting wire. This is common in tropical areas where low-income farmers can demarcate properties and reduce maintenance of fence posts that otherwise deteriorate rapidly. Many other benefits can be obtained depending on the specie ...
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Financial Services Companies Based In Massachusetts
Finance is the study and discipline of money, currency and capital assets. It is related to, but not synonymous with economics, the study of production, distribution, and consumption of money, assets, goods and services (the discipline of financial economics bridges the two). Finance activities take place in financial systems at various scopes, thus the field can be roughly divided into personal, corporate, and public finance. In a financial system, assets are bought, sold, or traded as financial instruments, such as currencies, loans, bonds, shares, stocks, options, futures, etc. Assets can also be banked, invested, and insured to maximize value and minimize loss. In practice, risks are always present in any financial action and entities. A broad range of subfields within finance exist due to its wide scope. Asset, money, risk and investment management aim to maximize value and minimize volatility. Financial analysis is viability, stability, and profitabil ...
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Financial Services Companies Established In 2002
Finance is the study and discipline of money, currency and capital assets. It is related to, but not synonymous with economics, the study of production, distribution, and consumption of money, assets, goods and services (the discipline of financial economics bridges the two). Finance activities take place in financial systems at various scopes, thus the field can be roughly divided into personal, corporate, and public finance. In a financial system, assets are bought, sold, or traded as financial instruments, such as currencies, loans, bonds, shares, stocks, options, futures, etc. Assets can also be banked, invested, and insured to maximize value and minimize loss. In practice, risks are always present in any financial action and entities. A broad range of subfields within finance exist due to its wide scope. Asset, money, risk and investment management aim to maximize value and minimize volatility. Financial analysis is viability, stability, and profitability assessmen ...
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American Companies Established In 2002
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ...
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Disgorgement
Disgorgement is defined by ''Black's Law Dictionary'' as "the act of giving up something (such as profits illegally obtained) on demand or by legal compulsion." Overview Disgorgement is a remedy or penalty used in US securities law. For example, disgorgement of short-swing profits is the remedy prescribed by ยง 16(b) of the Securities Exchange Act of 1934. The second edition of ''American Jurisprudence'' states that: Although not labelled "disgorgement," recovery of profits from the wrongful use of a patent or copyright belonging to another person or entity has a long history in US law. The US Supreme Court, in ''Sheldon v. Metro-Goldwyn Pictures Corp.'', 309 U.S. 390, 399-400 (1940), stated: In ''Kokesh v. SEC'', 137 S. Ct. 1635 (2017), the US Supreme Court unanimously disagreed with the view of the Security and Exchange Commission (SEC) that disgorgement in the case was remedial but held that disgorgement payments to the SEC in the case were penalties. The decision rai ...
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Short (finance)
In finance, being short in an asset means investing in such a way that the investor will profit if the value of the asset falls. This is the opposite of a more conventional "long" position, where the investor will profit if the value of the asset rises. There are a number of ways of achieving a short position. The most fundamental method is "physical" selling short or short-selling, which involves borrowing assets (often securities such as shares or bonds) and selling them. The investor will later purchase the same number of the same type of securities in order to return them to the lender. If the price has fallen in the meantime, the investor will have made a profit equal to the difference. Conversely, if the price has risen then the investor will bear a loss. The short seller must usually pay a fee to borrow the securities (charged at a particular rate over time, similar to an interest payment), and reimburse the lender for any cash returns such as dividends that were due ...
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Venture Round
A venture round is a type of funding round used for venture capital financing, by which startup companies obtain investment, generally from venture capitalists and other institutional investors. The availability of venture funding is among the primary stimuli for the development of new companies and technologies. Features Parties *Founders or stakeholders. Introduce companies to investors. *A lead investor, typically the best known or most aggressive venture capital firm that is participating in the investment, or the one contributing the largest amount of cash. The lead investor typically oversees most of the negotiation, legal work, due diligence, and other formalities of the investment. It may also introduce the company to other investors, generally in an informal unpaid capacity. *Co-investors, other major investors who contribute alongside the lead investor *Follow-on or piggyback investors. Typically angel investors, high-net worth individuals, family offices, institut ...
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Down Syndrome
Down syndrome or Down's syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. It is usually associated with physical growth delays, mild to moderate intellectual disability, and characteristic facial features. The average IQ of a young adult with Down syndrome is 50, equivalent to the mental ability of an eight- or nine-year-old child, but this can vary widely. The parents of the affected individual are usually genetically normal. The probability increases from less than 0.1% in 20-year-old mothers to 3% in those of age 45. The extra chromosome is believed to occur by chance, with no known behavioral activity or environmental factor that changes the probability. Down syndrome can be identified during pregnancy by prenatal screening followed by diagnostic testing or after birth by direct observation and genetic testing. Since the introduction of screening, Down syndrome pregnancies are often abor ...
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Sequenom
Sequenom () is an American company based in San Diego, California. It develops enabling molecular technologies, and highly sensitive laboratory genetic tests for NIPT. Sequenom's wholly owned subsidiarity, Sequenom Center for Molecular Medicine (SCMM), offers multiple clinical molecular genetics tests to patients, including MaterniT21, plus a noninvasive prenatal test for trisomy 21, trisomy 18, and trisomy 13, and the SensiGene RHD Fetal RHD genotyping test. In June 2014 the company sold its biosciences unit to Agena Bioscience for up to $35.8 million. In July 2016, it was announced that diagnostic and testing giant LabCorp will acquire Sequenom, paying $2.40 for every outstanding share of Sequenom stock. The acquisition was completed in September 2016. Competition Companies also offering non-invasive prenatal genetic testing include Ariosa, Ravgen, Illumina (Verinata Health), PerkinElmer and Natera (The Panorama Prenatal Test). Other companies and universities that are wo ...
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