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Quantitative Susceptibility Mapping
Quantitative Susceptibility Mapping (QSM) provides a novel contrast mechanism in Magnetic Resonance Imaging (MRI) different from traditional Susceptibility Weighted Imaging. The voxel intensity in QSM is linearly proportional to the underlying tissue apparent magnetic susceptibility, which is useful for chemical identification and quantification of specific biomarkers including iron, calcium, gadolinium, and super paramagnetic iron oxide (SPIO) nano-particles. QSM utilizes phase images, solves the magnetic field to susceptibility source inverse problem, and generates a three-dimensional susceptibility distribution. Due to its quantitative nature and sensitivity to certain kinds of material, potential QSM applications include standardized quantitative stratification of cerebral microbleeds and neurodegenerative disease, accurate gadolinium quantification in contrast enhanced MRI, and direct monitoring of targeted theranostic drug biodistribution in nanomedicine. Background In ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
3D VR Image 200
3-D, 3D, or 3d may refer to: Science, technology, and mathematics Relating to three-dimensionality * Three-dimensional space ** 3D computer graphics, computer graphics that use a three-dimensional representation of geometric data ** 3D film, a motion picture that gives the illusion of three-dimensional perception ** 3D modeling, developing a representation of any three-dimensional surface or object ** 3D printing, making a three-dimensional solid object of a shape from a digital model ** 3D display, a type of information display that conveys depth to the viewer ** 3D television, television that conveys depth perception to the viewer ** Stereoscopy, any technique capable of recording three-dimensional visual information or creating the illusion of depth in an image Other uses in science and technology or commercial products * 3D projection * 3D rendering * 3D scanning, making a digital representation of three-dimensional objects * 3D video game (other) * 3-D Secure, a s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Magic Angle
The magic angle is a precisely defined angle, the value of which is approximately 54.7356°. The magic angle is a root of a second-order Legendre polynomial, , and so any interaction which depends on this second-order Legendre polynomial vanishes at the magic angle. This property makes the magic angle of particular importance in magic angle spinning solid-state NMR spectroscopy. In magnetic resonance imaging, structures with ordered collagen, such as tendons and ligaments, oriented at the magic angle may appear hyperintense in some sequences; this is called the magic angle artifact or effect. Mathematical definition The magic angle ''θ''m is : \theta_\mathrm = \arccos \frac = \arctan \sqrt \approx 0.955\,32\ \text \approx 54.7^\circ \! , where arccos and arctan are the inverse cosine and tangent functions respectively. ''θ''m is the angle between the space diagonal of a cube and any of its three connecting edges, see image. Another representation of the magic angle is half o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
L1 Norm
In mathematics, the spaces are function spaces defined using a natural generalization of the -norm for finite-dimensional vector spaces. They are sometimes called Lebesgue spaces, named after Henri Lebesgue , although according to the Bourbaki group they were first introduced by Frigyes Riesz . spaces form an important class of Banach spaces in functional analysis, and of topological vector spaces. Because of their key role in the mathematical analysis of measure and probability spaces, Lebesgue spaces are used also in the theoretical discussion of problems in physics, statistics, economics, finance, engineering, and other disciplines. Applications Statistics In statistics, measures of central tendency and statistical dispersion, such as the mean, median, and standard deviation, are defined in terms of metrics, and measures of central tendency can be characterized as solutions to variational problems. In penalized regression, "L1 penalty" and "L2 penalty" refer to penali ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroimaging
Neuroimaging is the use of quantitative (computational) techniques to study the structure and function of the central nervous system, developed as an objective way of scientifically studying the healthy human brain in a non-invasive manner. Increasingly it is also being used for quantitative studies of brain disease and psychiatric illness. Neuroimaging is a highly multidisciplinary research field and is not a medical specialty. Neuroimaging differs from neuroradiology which is a medical specialty and uses brain imaging in a clinical setting. Neuroradiology is practiced by radiologists who are medical practitioners. Neuroradiology primarily focuses on identifying brain lesions, such as vascular disease, strokes, tumors and inflammatory disease. In contrast to neuroimaging, neuroradiology is qualitative (based on subjective impressions and extensive clinical training) but sometimes uses basic quantitative methods. Functional brain imaging techniques, such as functional magn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In Vivo
Studies that are ''in vivo'' (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism. This is not to be confused with experiments done ''in vitro'' ("within the glass"), i.e., in a laboratory environment using test tubes, Petri dishes, etc. Examples of investigations ''in vivo'' include: the pathogenesis of disease by comparing the effects of bacterial infection with the effects of purified bacterial toxins; the development of non-antibiotics, antiviral drugs, and new drugs generally; and new surgical procedures. Consequently, animal testing and clinical trials are major elements of ''in vivo'' research. ''In vivo'' testing is often employed over ''in vitro'' because it is better suited for observing the overall effects of an experiment on a living subject. In dr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ex Vivo
''Ex vivo'' (Latin: "out of the living") literally means that which takes place outside an organism. In science, ''ex vivo'' refers to experimentation or measurements done in or on tissue from an organism in an external environment with minimal alteration of natural conditions. Testing the effect of compounds on skin biopsies is an example of ''ex vivo'' research, while isolating the primary cells from that biopsy and creating a 3D cell culture model is an example of ''in vitro'' research. Both use human tissues, but the former is a more complex and translational environment for drug testing. A primary advantage of using ''ex vivo'' tissues is the ability to perform tests or measurements that would otherwise not be possible or ethical in living subjects. Tissues may be experimented on in many ways, including in part (e.g. cardiac contractility models using atrial pectinate muscles) or as whole organs (e.g. isolated perfused heart model). Examples of ''ex vivo'' models include: ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In Vitro
''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called " test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, '' in vivo'' studies are those conducted in living organisms, including humans, and whole plants. Definition ''In vitro'' ( la, in glass; often not italicized in English usage) studies are conducted using components of an organism that have been isolate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oversampling
In signal processing, oversampling is the process of sampling a signal at a sampling frequency significantly higher than the Nyquist rate. Theoretically, a bandwidth-limited signal can be perfectly reconstructed if sampled at the Nyquist rate or above it. The Nyquist rate is defined as twice the bandwidth of the signal. Oversampling is capable of improving resolution and signal-to-noise ratio, and can be helpful in avoiding aliasing and phase distortion by relaxing anti-aliasing filter performance requirements. A signal is said to be oversampled by a factor of ''N'' if it is sampled at ''N'' times the Nyquist rate. Motivation There are three main reasons for performing oversampling: to improve anti-aliasing performance, to increase resolution and to reduce noise. Anti-aliasing Oversampling can make it easier to realize analog anti-aliasing filters. Without oversampling, it is very difficult to implement filters with the sharp cutoff necessary to maximize use of the available ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gd Cosmos
GD, Gd, or gd may refer to: Arts and entertainment * G-Dragon (born 1988), leader of the South Korean musical group Big Bang * Grateful Dead, an American rock band * Green Day, an American rock band * ''Geometry Dash'', a rhythm-based video game for smartphones and PC *Good Drawing, in text this means that the drawing of a person is good Business and economics * Gardner Denver, a US-based manufacturer of industrial equipment * General Dynamics, a US-based defense conglomerate * Good Delivery, a specification for gold and silver bars * Great Depression, a sudden collapse of the global economy in the 1920s * Composite Index on the Athens Stock Exchange (stock symbol GD) Math, science and technology Biology and medicine * Gaucher's disease, a lipid storage diseases * Gender dysphoria, distress caused by a difference between the sex and gender a person was assigned at birth * Generalized dystonia, a neurological movement disorder * Gestational diabetes, a form of diabetes associated ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
NMR In Biomedicine
''NMR in Biomedicine'' is a monthly peer-reviewed medical journal published since 1988 by John Wiley & Sons. It publishes original full-length papers, rapid communications, and review articles in which magnetic resonance spectroscopy or imaging methods are used to investigate physiological, biochemical, biophysical, or medical problems. The current editor-in-chief is John R. Griffiths (Cancer Research UK). Highest cited articles The following articles have been cited most frequently: # "The basis of anisotropic water diffusion in the nervous system - a technical review", 15 (7-8) Nov-Dec 2002: 435–455, Beaulieu C. # "A review of chemical issues in H-1-NMR spectroscopy - n-acetyl-l-aspartate, creatine and choline", 4 (2) Apr 1991: 47–52, Miller BL. # "Fiber tracking: principles and strategies - a technical review", 15 (7-8) Nov-Dec 2002: 468–480, DMori S, van Zijl PCM. # "Inferring microstructural features and the physiological state of tissues from diffusion-weighted images ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harmonic Function
In mathematics, mathematical physics and the theory of stochastic processes, a harmonic function is a twice continuously differentiable function f: U \to \mathbb R, where is an open subset of that satisfies Laplace's equation, that is, : \frac + \frac + \cdots + \frac = 0 everywhere on . This is usually written as : \nabla^2 f = 0 or :\Delta f = 0 Etymology of the term "harmonic" The descriptor "harmonic" in the name harmonic function originates from a point on a taut string which is undergoing harmonic motion. The solution to the differential equation for this type of motion can be written in terms of sines and cosines, functions which are thus referred to as ''harmonics''. Fourier analysis involves expanding functions on the unit circle in terms of a series of these harmonics. Considering higher dimensional analogues of the harmonics on the unit ''n''-sphere, one arrives at the spherical harmonics. These functions satisfy Laplace's equation and over time "harmonic" ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
High-pass Filter
A high-pass filter (HPF) is an electronic filter that passes signals with a frequency higher than a certain cutoff frequency and attenuates signals with frequencies lower than the cutoff frequency. The amount of attenuation for each frequency depends on the filter design. A high-pass filter is usually modeled as a linear time-invariant system. It is sometimes called a low-cut filter or bass-cut filter in the context of audio engineering. High-pass filters have many uses, such as blocking DC from circuitry sensitive to non-zero average voltages or radio frequency devices. They can also be used in conjunction with a low-pass filter to produce a bandpass filter. In the optical domain filters are often characterised by wavelength rather than frequency. High-pass and low-pass have the opposite meanings, with a "high-pass" filter (more commonly "long-pass") passing only ''longer'' wavelengths (lower frequencies), and vice versa for "low-pass" (more commonly "short-pass"). Descrip ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
