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Quantitative Susceptibility Mapping
Quantitative susceptibility mapping (QSM) provides a novel contrast mechanism in magnetic resonance imaging (MRI) different from traditional susceptibility weighted imaging. The voxel intensity in QSM is linearly proportional to the underlying tissue apparent magnetic susceptibility, which is useful for chemical identification and quantification of specific biomarkers including iron, calcium, gadolinium, and super paramagnetic iron oxide (SPIO) nano-particles. QSM utilizes phase images, solves the magnetic field to susceptibility source inverse problem, and generates a three-dimensional susceptibility distribution. Due to its quantitative nature and sensitivity to certain kinds of material, potential QSM applications include standardized quantitative stratification of cerebral microbleeds and neurodegenerative disease, accurate gadolinium quantification in contrast enhanced MRI, and direct monitoring of targeted theranostic drug biodistribution in nanomedicine. Background In M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
3D VR Image 200
3D, 3-D, 3d, or Three D may refer to: Science, technology, and mathematics * A three-dimensional space in mathematics Relating to three-dimensionality * 3D computer graphics 3D computer graphics, sometimes called Computer-generated imagery, CGI, 3D-CGI or three-dimensional Computer-generated imagery, computer graphics, are graphics that use a three-dimensional representation of geometric data (often Cartesian coor ..., computer graphics that use a three-dimensional representation of geometric data * 3D display, a type of information display that conveys depth to the viewer * 3D film, a motion picture that gives the illusion of three-dimensional perception * 3D modeling, developing a representation of any three-dimensional surface or object * 3D printing, making a three-dimensional solid object of a shape from a digital model * 3D television, television that conveys depth perception to the viewer * 3D projection * 3D rendering * 3D scanning, making a digital representation of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
K-space (MRI)
In magnetic resonance imaging (MRI), the ''k''-space or ''reciprocal space'' (a mathematical space of spatial frequencies) is obtained as the 2D or 3D Fourier transform of the image measured. It was introduced in 1979 by Likes and in 1983 by Ljunggren and Twieg. In MRI physics, complex values are sampled in ''k''-space during an MR measurement in a premeditated scheme controlled by a '' pulse sequence'', i.e. an accurately timed sequence of radiofrequency and gradient pulses. In practice, ''k''-space often refers to the ''temporary image space'', usually a matrix, in which data from digitized MR signals are stored during data acquisition. When ''k''-space is full (at the end of the scan) the data are mathematically processed to produce a final image. Thus ''k''-space holds ''raw'' data before ''reconstruction''. It can be formulated by defining ''wave vectors'' k_\mathrm and k_\mathrm for "frequency encoding" (FE) and "phase encoding" (PE): :k_\mathrm=\bar G_\mathrmm\Delta t :k_ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroimaging
Neuroimaging is the use of quantitative (computational) techniques to study the neuroanatomy, structure and function of the central nervous system, developed as an objective way of scientifically studying the healthy human brain in a non-invasive manner. Increasingly it is also being used for quantitative research studies of brain disease and psychiatric illness. Neuroimaging is highly multidisciplinary involving neuroscience, computer science, psychology and statistics, and is not a medical specialty. Neuroimaging is sometimes confused with neuroradiology. Neuroradiology is a medical specialty that uses non-statistical brain imaging in a clinical setting, practiced by radiologists who are medical practitioners. Neuroradiology primarily focuses on recognizing brain lesions, such as vascular diseases, strokes, tumors, and inflammatory diseases. In contrast to neuroimaging, neuroradiology is qualitative (based on subjective impressions and extensive clinical training) but sometime ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In Vivo
Studies that are ''in vivo'' (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism. Examples of investigations ''in vivo'' include: the pathogenesis of disease by comparing the effects of bacterial infection with the effects of purified bacterial toxins; the development of non-antibiotics, antiviral drugs, and new drugs generally; and new surgical procedures. Consequently, animal testing and clinical trials are major elements of ''in vivo'' research. ''In vivo'' testing is often employed over ''in vitro'' because it is better suited for observing the overall effects of an experiment on a living subject. In drug discovery, for example, verification of efficacy ''in vivo'' is crucial, because ''in vitro'' assays can sometimes yield misleading results with drug c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ex Vivo
refers to biological studies involving tissues, organs, or cells maintained outside their native organism under controlled laboratory conditions. By carefully managing factors such as temperature, oxygenation, nutrient delivery, and perfusing a nutrient solution through the tissue's vasculature, researchers sustain function long enough to conduct experiments that would be difficult or unethical in a living body. ''Exvivo'' models occupy a middle ground between '' in vitro'' () models, which typically use isolated cells, and '' in vivo'' () studies conducted inside living organisms, offering both experimental control and physiological relevance. ''Ex vivo'' platforms support pharmacologic screening, toxicology testing, transplant evaluation, developmental biology, and investigations of disease-mechanism research across medicine and biology, from cardiology and neuroscience to dermatology and orthopedics. Because they often use human tissues obtained from clinical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In Vitro
''In vitro'' (meaning ''in glass'', or ''in the glass'') Research, studies are performed with Cell (biology), cells or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, ''in vivo'' studies are those conducted in living organisms, including humans, known as clinical trials, and whole plants. Definition ''In vitro'' (Latin language, Latin for "in glass"; often not italicized in English usage) studies are conducted ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oversampling
In signal processing, oversampling is the process of sampling (signal processing), sampling a signal at a sampling frequency significantly higher than the Nyquist rate. Theoretically, a bandwidth-limited signal can be perfectly reconstructed if sampled at the Nyquist rate or above it. The Nyquist rate is defined as twice the Bandwidth (signal processing), bandwidth of the signal. Oversampling is capable of improving Resolution (audio), resolution and signal-to-noise ratio, and can be helpful in avoiding aliasing and phase distortion by relaxing anti-aliasing filter performance requirements. A signal is said to be oversampled by a factor of ''N'' if it is sampled at ''N'' times the Nyquist rate. Motivation There are three main reasons for performing oversampling: to improve anti-aliasing performance, to increase resolution and to reduce noise. Anti-aliasing Oversampling can make it easier to realize analog anti-aliasing filters. Without oversampling, it is very difficult to impl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gd Cosmos
GD may refer to: Arts and entertainment * G-Dragon (born 1988), leader of the South Korean musical group Big Bang * Grateful Dead, an American rock band * Green Day, an American rock band * ''Geometry Dash'', a side-scrolling music platforming video game Business and economics * Gardner Denver, a US-based manufacturer of industrial equipment * General Dynamics, a US-based defense conglomerate * Good Delivery, a specification for gold and silver bars * '' Gudbrandsdølen Dagningen'', a Norwegian newspaper * Composite Index on the Athens Stock Exchange (stock symbol GD) Mathematics, science and technology Biology and medicine * Gaucher's disease, a lipid storage diseases * Gender dysphoria, distress caused by a difference between the sex and gender a person was assigned at birth * Generalized dystonia, a neurological movement disorder * Gestational diabetes, a form of diabetes associated with pregnancy * Graves' disease, an autoimmune thyroid disorder * ''Gain of deiodina ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
NMR In Biomedicine
''NMR in Biomedicine'' is a monthly peer-reviewed medical journal published since 1988 by John Wiley & Sons. It publishes original full-length papers, rapid communications, and review articles in which magnetic resonance spectroscopy or imaging methods are used to investigate physiological, biochemical, biophysical, or medical problems. The current editor-in-chief is John R. Griffiths (Cancer Research UK). Highest cited articles The following articles have been cited most frequently: # "The basis of anisotropic water diffusion in the nervous system - a technical review", 15 (7-8) Nov-Dec 2002: 435–455, Beaulieu C. # "A review of chemical issues in H-1-NMR spectroscopy - n-acetyl-l-aspartate, creatine and choline", 4 (2) Apr 1991: 47–52, Miller BL. # "Fiber tracking: principles and strategies - a technical review", 15 (7-8) Nov-Dec 2002: 468–480, DMori S, van Zijl PCM. # "Inferring microstructural features and the physiological state of tissues from diffusion-weighted image ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harmonic Function
In mathematics, mathematical physics and the theory of stochastic processes, a harmonic function is a twice continuously differentiable function f\colon U \to \mathbb R, where is an open subset of that satisfies Laplace's equation, that is, \frac + \frac + \cdots + \frac = 0 everywhere on . This is usually written as \nabla^2 f = 0 or \Delta f = 0 Etymology of the term "harmonic" The descriptor "harmonic" in the name "harmonic function" originates from a point on a taut string which is undergoing harmonic motion. The solution to the differential equation for this type of motion can be written in terms of sines and cosines, functions which are thus referred to as "harmonics." Fourier analysis involves expanding functions on the unit circle in terms of a series of these harmonics. Considering higher dimensional analogues of the harmonics on the unit ''n''-sphere, one arrives at the spherical harmonics. These functions satisfy Laplace's equation and, over time, "harmon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
High-pass Filter
A high-pass filter (HPF) is an electronic filter that passes signals with a frequency higher than a certain cutoff frequency and attenuates signals with frequencies lower than the cutoff frequency. The amount of attenuation for each frequency depends on the filter design. A high-pass filter is usually modeled as a linear time-invariant system. It is sometimes called a low-cut filter or bass-cut filter in the context of audio engineering. High-pass filters have many uses, such as blocking DC from circuitry sensitive to non-zero average voltages or radio frequency devices. They can also be used in conjunction with a low-pass filter to produce a band-pass filter. In the optical domain filters are often characterised by wavelength rather than frequency. High-pass and low-pass have the opposite meanings, with a "high-pass" filter (more commonly "short-pass") passing only ''shorter'' wavelengths (higher frequencies), and vice versa for "low-pass" (more commonly "long-pass"). De ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brain
The brain is an organ (biology), organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head (cephalization), usually near organs for special senses such as visual perception, vision, hearing, and olfaction. Being the most specialized organ, it is responsible for receiving information from the sensory nervous system, processing that information (thought, cognition, and intelligence) and the coordination of motor control (muscle activity and endocrine system). While invertebrate brains arise from paired segmental ganglia (each of which is only responsible for the respective segmentation (biology), body segment) of the ventral nerve cord, vertebrate brains develop axially from the midline dorsal nerve cord as a brain vesicle, vesicular enlargement at the rostral (anatomical term), rostral end of the neural tube, with centralized control over all body segments. All vertebr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
