|
Punicalin
Punicalin is an ellagitannin. It can be found in ''Punica granatum'' (pomegranate) or in the leaves of ''Terminalia catappa'', a plant used to treat dermatitis and hepatitis. It is also reported in ''Combretum glutinosum'', all three species being Myrtales, the two last being Combretaceae. It is a highly active carbonic anhydrase inhibitor. Chemistry The molecule contains a gallagic acid component linked to a glucose Glucose is a simple sugar with the molecular formula . Glucose is overall the most abundant monosaccharide, a subcategory of carbohydrates. Glucose is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, using .... References Pomegranate ellagitannins Carbonic anhydrase inhibitors {{aromatic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pomegranate Ellagitannins
The pomegranate ellagitannins, which include punicalagin isomers, are ellagitannins found in the sarcotestas, rind (peel), bark or heartwood of pomegranates (''Punica granatum''). Chemistry As the chemistry of punicalagins became known it was found to be not unique to pomegranate. Punicalagins are present in numerous species of the genus ''Terminalia (plant), Terminalia'', species ''Terminalia chebula, chebula'' Retz. (“Fructus Chebulae”), ''Terminalia myriocarpa, myriocarpa'', ''Terminalia catappa, catappa'' and Terminalia citrina, citrina (tropical flowering trees historically used in African traditional medicine for antibiotic and antifungal purposes). They have also been isolated from ''Cistus salvifolius'' (a Mediterranean shrub) and ''Combretum molle'' (an African shrub). Pomegranate fruits natural phenols can be extracted with ethyl acetate and fractionation can afford the ellagitannin punicalagins. Dietary supplementation A few dietary supplements and nutritional ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Punica Granatum
The pomegranate (''Punica granatum'') is a fruit-bearing deciduous shrub in the family Lythraceae, subfamily Punicoideae, that grows between tall. The pomegranate was originally described throughout the Mediterranean region. It was introduced into Spanish America in the late 16th century and into California by Spanish settlers in 1769. The fruit is typically in season in the Southern Hemisphere from March to May, and in the Northern Hemisphere from September to February. As intact sarcotestas or juice, pomegranates are used in baking, cooking, juice blends, meal garnishes, smoothies, and alcoholic beverages, such as cocktails and wine. Pomegranates are widely cultivated throughout the Middle East and Caucasus region, north and tropical Africa, Iran, Armenia, the Indian subcontinent, Central Asia, the drier parts of Southeast Asia, and the Mediterranean Basin. Etymology The name pomegranate derives from medieval Latin "apple" and "seeded". Possibly stemming from the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Terminalia Catappa
''Terminalia catappa'' is a large tropical tree in the leadwood tree family, Combretaceae, native to Asia, Australia, the Pacific, Madagascar and Seychelles. Common names in English include country almond, Indian almond, Malabar almond, sea almond, tropical almond, beach almond and false kamani. Description The tree grows to tall, with an upright, symmetrical crown and horizontal branches. The fruit are corky and light, and dispersed by water. As the tree gets older, its crown becomes more flattened to form a spreading, vase shape. Its branches are distinctively arranged in tiers. The leaves are large, long and broad, ovoid, glossy dark green, and leathery. They are dry-season deciduous; before falling, they turn pinkish-reddish or yellow-brown, due to pigments such as violaxanthin, lutein, and zeaxanthin. The trees are monoecious, with distinct male and female flowers on the same tree. Both are in diameter, white to greenish, inconspicuous with no petals; they are produced ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dermatitis
Dermatitis is inflammation of the skin, typically characterized by itchiness, redness and a rash. In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened. The area of skin involved can vary from small to covering the entire body. Dermatitis is often called eczema, and the difference between those terms is not standardized. The exact cause of the condition is often unclear. Cases may involve a combination of allergy and poor venous return. The type of dermatitis is generally determined by the person's history and the location of the rash. For example, irritant dermatitis often occurs on the hands of those who frequently get them wet. Allergic contact dermatitis occurs upon exposure to an allergen, causing a hypersensitivity reaction in the skin. Prevention of atopic dermatitis is typically with essential fatty acids, and may be treated with moisturizers and steroid creams. The steroid creams should generally be of mid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hepatitis
Hepatitis is inflammation of the liver tissue. Some people or animals with hepatitis have no symptoms, whereas others develop yellow discoloration of the skin and whites of the eyes (jaundice), poor appetite, vomiting, tiredness, abdominal pain, and diarrhea. Hepatitis is ''acute'' if it resolves within six months, and '' chronic'' if it lasts longer than six months. Acute hepatitis can resolve on its own, progress to chronic hepatitis, or (rarely) result in acute liver failure. Chronic hepatitis may progress to scarring of the liver (cirrhosis), liver failure, and liver cancer. Hepatitis is most commonly caused by the virus ''hepatovirus A'', '' B'', '' C'', '' D'', and '' E''. Other viruses can also cause liver inflammation, including cytomegalovirus, Epstein–Barr virus, and yellow fever virus. Other common causes of hepatitis include heavy alcohol use, certain medications, toxins, other infections, autoimmune diseases, and non-alcoholic steatohepatitis (NASH). Hepa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Combretum Glutinosum
''Combretum glutinosum'' is a shrub species of the genus ''Combretum'', found in the Sahel belt in parts of Senegal, Burkina Faso, Ghana, Mali, the Gambia, Niger, Nigeria and Cameroon, across to parts of Sudan. It is known as dooki in Pulaar, Kantakara in Hausa, rat in Wolof and jambakatan kè in Maninka. Its synonyms are ''Combretum cordofanum'' Engl. & Diels, ''C. passargei'' Engl. & Diels, ''C. leonense'' Engl. & Diels. Habitat ''Combretum glutinosum'' tends to grow in savanna type forests, in several soil types but is best suited to sandy and free draining soils. It is drought resistant and grows in areas of annual rainfall of . Its growth is fast and profuse. Plant growth As a bushy shrub the plant grows up to with an open crown with low branches that droop down, and is deciduous. The trunk is usually twisted and low branched, with grey-black rough bark. The thick leathery green leaves have a gummy feel to them and are glutinous when young. The plant flowers during the dr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Myrtales
The Myrtales are an order of flowering plants placed as a sister to the eurosids II clade as of the publishing of the ''Eucalyptus grandis'' genome in June 2014. The APG III system of classification for angiosperms still places it within the eurosids. This finding is corroborated by the placement of the Myrtales in the Malvid clade by the One Thousand Plant Transcriptomes Initiative. The following families are included as of APGIII: * Alzateaceae S. A. Graham * Combretaceae R. Br. ( leadwood family) * Crypteroniaceae A. DC. * Lythraceae J. St.-Hil. ( loosestrife and pomegranate family) * Melastomataceae Juss. (including Memecylaceae DC.) * Myrtaceae Juss. (myrtle family; including Heteropyxidaceae Engl. & Gilg, Psiloxylaceae Croizat) * Onagraceae Juss. (evening primrose and Fuchsia family) * Penaeaceae Sweet ex Guill. (including Oliniaceae Arn., Rhynchocalycaceae L. A. S. Johnson & B. G. Briggs) * Vochysiaceae A. St.-Hil. The Cronquist system gives essentially the same compo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Combretaceae
The Combretaceae, often called the white mangrove family, are a family of flowering plants in the order Myrtales. The family includes about 530 species of trees, shrubs, and lianas in ca 10 genera. The family includes the leadwood tree, ''Combretum imberbe''. Three genera, ''Conocarpus'', ''Laguncularia'', and ''Lumnitzera'', grow in mangrove habitats (mangals). The Combretaceae are widespread in the subtropics and tropics. Some members of this family produce useful construction timber, such as idigbo from ''Terminalia ivorensis''. The commonly cultivated ''Quisqualis indica'' is now placed in the genus ''Combretum''. Many plants in the Quisqualis species contain the Non-proteinogenic amino acid excitotoxin Quisqualic acid, a potent AMPA agonist.Excitotoxic cell death and delayed rescue in human neurons derived from NT2 cells, M Munir, L Lu and P Mcgonigl, Journal of Neuroscience, Vol 15, 7847–7860 White mangroves The family name comes from the type genus ''Combretum''; it also ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carbonic Anhydrase Inhibitor
Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase. Their clinical use has been established as anti-glaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, gastric and duodenal ulcers, idiopathic intracranial hypertension, neurological disorders, or osteoporosis. Medical uses Carbonic anhydrase inhibitors are primarily used for the treatment of glaucoma. They may also be used to treat seizure disorder and acute mountain sickness. Because they encourage solubilization and excretion of uric acid, they can be used in the treatment of gout. Glaucoma Acetazolamide is an inhibitor of carbonic anhydrase. It is used for glaucoma, epilepsy (rarely), idiopathic intracranial hypertension, and altitude sickness. For the reduction of intraocular pressure (IOP), acetazolamide inactivates carbonic anhydrase and interferes with the sodium pump, which decreases aqueous humor formation and thus lowe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gallagic Acid
Gallagic acid is a polyphenolic chemical compound that can be found in the ellagitannins, a type of tannin, found in ''Punica granatum'' (pomegranate).Antioxidant, antimalarial and antimicrobial activities of tannin-rich fractions, ellagitannins and phenolic acids from Punica granatum L. Reddy Muntha K., Gupta Sashi K., Jacob Melissa R., Khan Shabana I. and Ferreira Daneel, Planta medica, 2007, vol. 73, no5, pp. 461-467, It is a building block of the corresponding tannin punicalagin, punicalin, punicacortein C Punicacortein C is an ellagitannin, a phenolic compound. It is found in the bark of ''Punica granatum'' (pomegranate).Tannins and Related Compounds. XLI. : Isolation and Characterization of Novel Ellagitannins, Punicacorteins A, B, C, and D, and Pu ... and 2-O-galloyl-punicalin. See also * Gallagic acid dilactone (a.k.a. gallagyldilactone or terminalin) References Ellagitannins Pomegranate ellagitannins {{aromatic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glucose
Glucose is a simple sugar with the molecular formula . Glucose is overall the most abundant monosaccharide, a subcategory of carbohydrates. Glucose is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, using energy from sunlight, where it is used to make cellulose in cell walls, the most abundant carbohydrate in the world. In energy metabolism, glucose is the most important source of energy in all organisms. Glucose for metabolism is stored as a polymer, in plants mainly as starch and amylopectin, and in animals as glycogen. Glucose circulates in the blood of animals as blood sugar. The naturally occurring form of glucose is -glucose, while -glucose is produced synthetically in comparatively small amounts and is less biologically active. Glucose is a monosaccharide containing six carbon atoms and an aldehyde group, and is therefore an aldohexose. The glucose molecule can exist in an open-chain (acyclic) as well as ring (cyclic) form. Gluco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
