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Prometa
Gabasync is an ineffective treatment promoted for methamphetamine addiction, although it had also been claimed to be effective for dependence on alcohol or cocaine. It was marketed as PROMETA. The treatment, based loosely on the research of Spanish psychologist Juan Jose Legarda, involved a combination of three medications (gabapentin, flumazenil and hydroxyzine) as well as therapy. While the individual drugs had been approved by the FDA, their off-label use for addiction treatment has not. Gabasync was marketed by Hythiam, Inc. which is owned by Terren Peizer, a former junk bond trader. Hythiam has sought to patent the protocol and charges up to $15,000 per patient to license its use (of which half goes to the prescribing physician, and half to Hythiam). Lower rates are offered to the criminal justice system, where it has been used in several drug court pilot programs. In November 2011, the results of a double-blind, placebo-controlled study (financed by Hythiam and carried out ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Terren Peizer
Terren Scott Peizer, is an investor and company executive. He is the CEO of Acuitas Group Holdings and Neurmedix. He is also the CEO and chairman of Ontrak. He has held senior executive positions within technology and biotech companies, at Goldman Sachs and First Boston, and as a bond salesman at Drexel Burnham Lambert. Early life and education Peizer's hometown is Beachwood, Ohio. He attended Beachwood High School. Peizer graduated from the Wharton School of the University of Pennsylvania. Career In 1983, Peizer worked at Goldman Sachs and later worked at First Boston as a salesman. Michael Milken hired Peizer as a bond salesman at Drexel Burnham Lambert in 1985. He was the manager of David M. Solomon's account with Drexel and given a 3.5 million dollar salary and a $500.000 loan to invest in the partnership. Peizer worked directly under (and at the same desk as) Milken and admired him, sometimes pretending to be him on the phone, and calling him "Dad". When investigation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methamphetamine
Methamphetamine (contracted from ) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity. Methamphetamine was discovered in 1893 and exists as two enantiomers: levo-methamphetamine and dextro-methamphetamine. ''Methamphetamine'' properly refers to a specific chemical substance, the racemic free base, which is an equal mixture of levomethamphetamine and dextromethamphetamine in their pure amine forms. It is rarely prescribed over concerns involving human neurotoxicity and potential for recreational use as an aphrodisiac and euphoriant, among other concerns, as well as the availability of safer substitute drugs with comparable treatment efficacy such as Adderall and Vyvanse. Dextromethamphetamine is a stronger CNS stimulant than levomethamphetamine. Both racemic methamphetamine and dextromethamphetamine are illicitly trafficked ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gary, Indiana
Gary is a city in Lake County, Indiana, United States. The city has been historically dominated by major industrial activity and is home to U.S. Steel's Gary Works, the largest steel mill complex in North America. Gary is located along the southern shore of Lake Michigan about east of Chicago Loop, downtown Chicago, Illinois. The city is adjacent to the Indiana Dunes National Park, and is within the Chicago metropolitan area. Gary was named after lawyer Elbert Henry Gary, who was the founding chairman of the United States Steel Corporation. U.S. Steel had established the city as a company town to serve its steel mills. Although initially a very diverse city, after white flight in the 1970s, the city of Gary held the nation's highest percentage of African Americans for several decades. As of the 2020 United States Census, 2020 census the city's population was 70,093, making it Indiana's List of municipalities in Indiana, ninth-largest city. Like other Rust Belt cities, Gary's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Star (magazine)
''Star'' is an American celebrity tabloid magazine founded in 1974. The magazine is owned by American Media Inc. and overseen by AMI's Chief Content Officer, Dylan Howard. History ''Star'' was founded by Rupert Murdoch in 1974 as competition to the tabloid ''National Enquirer'' with its headquarters in New York City. In the late 1980s it moved its offices to Tarrytown, NY and in 1990 Murdoch sold the magazine to the ''Enquirer''s parent company American Media, Inc. (Murdoch now owns the ''New York Post'', which, although it has more of a regional, news-centered focus, still has significant celebrity coverage.) Originally an unstapled, inexpensive, supermarket tabloid printed on newsprint, ''Star'' was hugely successful but remained in the shadow of its longer-established stablemate. Along with the ''Enquirer'' its circulation declined with the advent of celebrity-driven television shows such as ''Entertainment Tonight'' and '' Hard Copy''. In 1999, AMI was bought by investor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lindsay Lohan
Lindsay Dee Lohan ( ; born July 2, 1986) is an American actress and singer. Born in New York City and raised on Long Island, Lohan was signed to Ford Models at the age of three. Having appeared as a regular on the television soap opera '' Another World'' at age 10, her breakthrough came in the Walt Disney Pictures film '' The Parent Trap'' (1998). The film's success led to appearances in the television films '' Life-Size'' (2000) and '' Get a Clue'' (2002), and the big-screen productions '' Freaky Friday'' (2003) and ''Confessions of a Teenage Drama Queen'' (2004). Lohan's early work won her childhood stardom, while the teen comedy sleeper hit '' Mean Girls'' (2004) affirmed her status as a teen idol and established her as a Hollywood leading actress. Lohan became known as a triple threat after signing with Casablanca Records and releasing two studio albums, the platinum-certified '' Speak'' (2004) and gold-certified '' A Little More Personal (Raw)'' (2005). She also star ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chris Farley
Christopher Crosby Farley (February 15, 1964 – December 18, 1997) was an American actor and comedian. Farley was known for his loud, energetic comedic style, and was a member of Chicago's Second City Theatre and later a cast member of the NBC sketch comedy show ''Saturday Night Live'' for five seasons from 1990 to 1995. He later went on to pursue a film career, appearing in films such as '' Airheads'', ''Tommy Boy'', ''Black Sheep'', ''Beverly Hills Ninja'', and '' Almost Heroes''. From his early acting days and through the height of his fame, Farley struggled with obesity and substance abuse. He died of a drug overdose at the age of 33. Early life Christopher Crosby Farley was born on February 15, 1964, in Madison, Wisconsin, and grew up in Maple Bluff. His father, Thomas John Farley Sr. (1936–99), owned an oil company, and his mother, Mary Anne (née Crosby), was a homemaker. He had four siblings: Tom Jr., Kevin, John, and Barbara. His cousin, Jim, is chief execut ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marketing Of Off-label Use
Marketing of off-label use is advertising the use of drugs for purposes not approved by the regional government. The practice is often illegal and has led to most of the largest pharmaceutical settlements after '' Franklin v. Parke-Davis'', in which a court ruled off-label marketing a violation of the False Claims Act. List of off-label promotion pharmaceutical settlements Many of the conflicts among the list of largest pharmaceutical settlements were because of off-label promotion. Franklin v. Parke-Davis In 1993, the FDA approved gabapentin, marketed by Pfizer under the name "Neurontin", only for treatment of seizures. Pfizer subsidiary Warner-Lambert illegally used scientific activities, including continuing medical education and research, to commercially promote gabapentin, so that within five years the drug was being widely used for the off-label treatment of pain and psychiatric conditions—conditions that had not been approved by FDA. In 2004, Warner-Lambert admitted ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Collin County, Texas
Collin County is located in the U.S. state of Texas. It is part of the Dallas-Fort Worth- Arlington metropolitan statistical area, and a small portion of the city of Dallas is in the county. At the 2020 United States census, the county's population is 1,064,465, making it the sixth-most populous county in Texas and the 43rd-largest county by population in the United States. Its county seat is McKinney. History Both the county and the county seat were named after Collin McKinney (1766-1861), one of the five men who drafted the Texas Declaration of Independence and the oldest of the 59 men who signed it. Geography According to the U.S. Census Bureau, the county has an area of , of which is land and (5.1%) is covered by water. Lakes * Lavon Lake Major highways Adjacent counties * Grayson County (north) * Fannin County (northeast) * Hunt County (east) * Rockwall County (southeast) * Dallas County (south) * Denton County (west) Communities Cities (shared with other ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Federal Way, Washington
Federal Way is a city in King County, Washington, United States. One of the most recently incorporated cities in the county, its population was 101,030 at the 2020 census. Federal Way is the tenth-largest city in Washington and the fifth-largest in King County. History Originally a logging settlement, the area was first called "Federal Way" in 1929. The name derived from Federal Highway U.S. 99 (now State Route 99 or Pacific Highway South), which ran from Everett and Seattle to Tacoma. The name "Federal Way" was first used in 1929 when five existing schools consolidated operations into School District #210 and planned construction of Federal Way High School, which opened in 1930 and gave its name to the school district. The local chamber of commerce adopted the name in the early 1950s. Attempts to incorporate the city were voted down in 1971, 1981 and 1985. The voters eventually approved incorporation as a city on February 28, 1990; the official act of incorporation wa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
60 Minutes
''60 Minutes'' is an American television news magazine broadcast on the CBS television network. Debuting in 1968, the program was created by Don Hewitt and Bill Leonard, who chose to set it apart from other news programs by using a unique style of reporter-centered investigation. In 2002, ''60 Minutes'' was ranked number six on ''TV Guide''s list of the " 50 Greatest TV Shows of All Time", and in 2013, it was ranked number 24 on the magazine's list of the "60 Best Series of All Time". ''The New York Times'' has called it "one of the most esteemed news magazines on American television". Originally airing in 1968, the program began as a bi-weekly television show hosted on CBS hosted by Mike Wallace and Harry Reasoner. The two sat on opposite sides of the cream-colored set, though the set's color was later changed to black, the color still used today. The show used a large stopwatch during transition periods and highlighted its topics through chroma key—both techniques are s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Ladenburg
John W. Ladenburg Sr. (born September 19, 1949) is an American attorney and politician. Ladenburg was appointed to the Tacoma City Council in 1982 and elected to a full term in 1984. He was elected Pierce County Prosecuting Attorney in 1986, defeating incumbent Bill Griffies. Ladenburg served as Pierce County prosecutor fothree termsbefore becoming the county executive in 2001. He was re-elected County Executive in 2004, terming out November 2008. One of Ladenburg's principal accomplishments in office was spearheading the development of Chambers Bay Golf Course in University Place, a municipal facility that hosted the 2010 United States Amateur and 2015 U.S. Open golf championships. Ladenburg was born in Leavenworth, Washington. In 1967 he graduated from Stadium High School in Tacoma, Washington. He received a B.A. degree in political science (honors) in 1971 and a J.D. degree in 1974, both from Gonzaga University. After graduation, he began a career as a trial attorney. Laden ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Washington
The University of Washington (UW, simply Washington, or informally U-Dub) is a public research university in Seattle, Washington. Founded in 1861, Washington is one of the oldest universities on the West Coast; it was established in Seattle approximately a decade after the city's founding. The university has a 703 acre main campus located in the city's University District, as well as campuses in Tacoma and Bothell. Overall, UW encompasses over 500 buildings and over 20 million gross square footage of space, including one of the largest library systems in the world with more than 26 university libraries, art centers, museums, laboratories, lecture halls, and stadiums. The university offers degrees through 140 departments, and functions on a quarter system. Washington is the flagship institution of the six public universities in Washington state. It is known for its medical, engineering, and scientific research. Washington is a member of the Association of American Univer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
