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Pluristem
Pluri Inc., formerly Pluristem Therapeutics, is an Israeli company engaged in the development of human placental adherent stromal cells for commercial use in disease treatment. According to the company's website, it extracts adult stem cells exclusively from postnatal placentas. Corporate history Pluristem was founded in 2001 by Shai Meretzki of the Technion, who made use of a stem cell patent which was developed during his Ph.D. studies at The Rappaport Faculty Of Medicine, Technion, under the supervision of Dr. Shosh Merchav, together with Professors Dov Zipori and Avinoam Kadouri from the Weizmann Institute of Science. In 2003, the NASDAQ-listed shell company A1 Software acquired all shares and patents belonging to Pluristem and changed its name to Pluristem Life Systems. In 2007 the name was changed again, this time to Pluristem Therapeutics Inc. Pluristem's shares are traded on the NASDAQ exchange and the Tel Aviv Stock Exchange, as well as on the Frankfurt Stock Exchange. ...
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Public Company
A public company is a company whose ownership is organized via shares of stock which are intended to be freely traded on a stock exchange or in over-the-counter markets. A public (publicly traded) company can be listed on a stock exchange (listed company), which facilitates the trade of shares, or not (unlisted public company). In some jurisdictions, public companies over a certain size must be listed on an exchange. In most cases, public companies are ''private'' enterprises in the ''private'' sector, and "public" emphasizes their reporting and trading on the public markets. Public companies are formed within the legal systems of particular states, and therefore have associations and formal designations which are distinct and separate in the polity in which they reside. In the United States, for example, a public company is usually a type of corporation (though a corporation need not be a public company), in the United Kingdom it is usually a public limited company (plc), i ...
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Peripheral Arterial Disease
Peripheral artery disease (PAD) is an abnormal narrowing of arteries other than those that supply the heart or brain. When narrowing occurs in the heart, it is called coronary artery disease, and in the brain, it is called cerebrovascular disease. Peripheral artery disease most commonly affects the legs, but other arteries may also be involved – such as those of the arms, neck, or kidneys. The classic symptom is leg pain when walking which resolves with rest, known as intermittent claudication. Other symptoms include skin ulcers, bluish skin, cold skin, or abnormal nail and hair growth in the affected leg. Complications may include an infection or tissue death which may require amputation; coronary artery disease, or stroke. Up to 50% of people with PAD do not have symptoms. The greatest risk factor for PAD is cigarette smoking. Other risk factors include diabetes, high blood pressure, kidney problems, and high blood cholesterol. The most common underlying mechanism of peri ...
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Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production. Symptoms may include feeling tired, shortness of breath, easy bruising and bleeding, and increased risk of infection. Occasionally, spread may occur to the brain, skin, or gums. As an acute leukemia, AML progresses rapidly, and is typically fatal within weeks or months if left untreated. Risk factors include smoking, previous chemotherapy or radiation therapy, myelodysplastic syndrome, and exposure to the chemical benzene. The underlying mechanism involves replacement of normal bone marrow with leukemia cells, which results in a drop in red blood cells, platelets, and normal white blood cells. Diagnosis is generally based on bone marrow aspiration and specific blood tests. AML has several subtypes for which treatments and outcomes may vary. The fir ...
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Ynetnews
Ynet (stylized as ynet) is one of the major Israeli news and general-content websites, and is the online outlet for the '' Yedioth Ahronot'' newspaper. However, most of Ynet's content is original work, published exclusively on the website and written by an independent staff. History Ynet was launched in June 2000 in Hebrew only; and in 2004 launched its online English edition Ynetnews. In addition, Ynet hosts the online version of Yedioth Aharanot's media group magazines: Laisha (which also operates Ynet's fashion section), Pnai Plus, Blazer, GO magazine, and Mentha. For two years, Ynet had also an Arabic version, which ceased to operate in May 2005. Ynet's main competition comes from Walla! Mako and Nana. Since 2008, Ynet is Israel's most popular internet portal, as measured by Google Trends. In celebration of Israel's independence day in 2005, Ynet conducted a poll to determine whom Ynet readers consider to be the greatest Israelis of all time. The top 200 results were publ ...
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Calcalist
''Calcalist'' ( he, כלכליסט, a Hebrew wordplay on ''The Economist'', from כלכלה) is an Israeli daily business newspaper and website. History and profile ''Calcalist'' was first published on 18 February 2008, and currently runs five days a week, with a weekend supplement included on Thursdays. The paper is published in Israel by the Yedioth Ahronoth Group. The group also publishes ''Yedioth Ahronoth'', the country's most widely circulated newspaper. The founder and publisher is Yoel Esteron, formerly the managing editor for ''Yedioth Ahronoth'', and its editor is Galit Hemi. It is circulated nationwide and its articles feature regularly in the biggest Israeli news website 'Ynet' as well as in the printed edition of Yedioth Ahronoth. The newspaper is divided into four sections: news, daily columns – some regular and some rotating (the rotating columns are marketing, legal, real estate, technology, career, personal finance, automotive and sports), the market – a sepa ...
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Reuters
Reuters ( ) is a news agency owned by Thomson Reuters Corporation. It employs around 2,500 journalists and 600 photojournalists in about 200 locations worldwide. Reuters is one of the largest news agencies in the world. The agency was established in London in 1851 by the German-born Paul Reuter. It was acquired by the Thomson Corporation of Canada in 2008 and now makes up the media division of Thomson Reuters. History 19th century Paul Reuter worked at a book-publishing firm in Berlin and was involved in distributing radical pamphlets at the beginning of the Revolutions in 1848. These publications brought much attention to Reuter, who in 1850 developed a prototype news service in Aachen using homing pigeons and electric telegraphy from 1851 on, in order to transmit messages between Brussels and Aachen, in what today is Aachen's Reuters House. Reuter moved to London in 1851 and established a news wire agency at the London Royal Exchange. Headquartered in London, Reuter' ...
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The Baltimore Sun
''The Baltimore Sun'' is the largest general-circulation daily newspaper based in the U.S. state of Maryland and provides coverage of local and regional news, events, issues, people, and industries. Founded in 1837, it is currently owned by Tribune Publishing. The ''Baltimore Sun's'' parent company, '' Tribune Publishing'', was acquired by Alden Global Capital, which operates its media properties through Digital First Media, in May 2021. History ''The Sun'' was founded on May 17, 1837, by printer/editor/publisher/owner Arunah Shepherdson Abell (often listed as "A. S. Abell") and two associates, William Moseley Swain, and Azariah H. Simmons, recently from Philadelphia, where they had started and published the '' Public Ledger'' the year before. Abell was born in Rhode Island, became a journalist with the ''Providence Patriot'' and later worked with newspapers in New York City and Boston.Van Doren, Charles and Robert McKendry, ed., ''Webster's American Biographies''. (Springfiel ...
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Compassionate Use
Expanded access or compassionate use is the use of an unapproved drug or medical device under special forms of investigational new drug applications (IND) or IDE application for devices, outside of a clinical trial, by people with serious or life-threatening conditions who do not meet the enrollment criteria for the clinical trial in progress. These programs go under various names, including early access, special access, or managed access program, compassionate use, compassionate access, named-patient access, temporary authorization for use, cohort access, and pre-approval access. In general the person and their doctor must apply for access to the investigational product, the company has to choose to cooperate, and the medicines regulatory agency needs to agree that the risks and possible benefits of the drug or device are understood well enough to determine if putting the person at risk has sufficient potential benefit. In some countries the government will pay for the drug or ...
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Ministry Of Health (Israel)
The Ministry of Health ( he, מִשְׂרַד הַבְּרִיאוּת, translit. ''Misrad HaBri'ut'') is a ministry in the Israeli government, responsible for formulating health policies. The ministry plans, supervises, licenses, and coordinates the country's health care services. In addition to overseeing health services provided by Kupat Holim and family health centers such as Tipat Halav, the ministry maintains general hospitals, psychiatric hospitals, mental health clinics, treatment programs for substance abuse, and facilities for the chronically ill. The current Minister of Health is Nitzan Horowitz. In February 2022, the ministry banned medical professionals in Israel from providing conversion therapy. List of ministers Deputy ministers See also *Health care in Israel * List of hospitals in Israel References External linksOfficial website {{authority control Health *Ministry of Health Health Israel Israel (; he, יִשְׂרָאֵל, ; ar, إ ...
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Declaration Of Helsinki
The Declaration of Helsinki (DoH, fi, Helsingin julistus, sv, Helsingforsdeklarationen) is a set of ethical principles regarding human experimentation developed originally in 1964 for the medical community by the World Medical Association (WMA). It is widely regarded as the cornerstone document on human research ethics. It is not a legally binding instrument under the international law, but instead draws its authority from the degree to which it has been codified in, or influenced, national or regional legislation and regulations. Its role was described by a Brazilian forum in 2000 in these words: "Even though the Declaration of Helsinki is the responsibility of the World Medical Association, the document should be considered the property of all humanity." Principles The Declaration is morally binding on physicians, and that obligation overrides any national or local laws or regulations, if the Declaration provides for a higher standard of protection of humans than the latter ...
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Hadassah Medical Center
Hadassah Medical Center ( he, הָמֶרְכָּז הָרְפוּאִי הֲדַסָּה) is an Israeli medical organization established in 1934 that operates two university hospitals in Jerusalem – one in Ein Karem and one in Mount Scopus –, as well as schools of medicine, dentistry, nursing, and pharmacology affiliated with the Hebrew University of Jerusalem. Its declared mission is to extend a "hand to all, without regard for race, religion or ethnic origin." The hospital was founded by the Hadassah Women's Zionist Organization of America, which continues to underwrite a large part of its budget today. The Medical Center ranks as the sixth-largest hospital complex in Israel. Across its two campuses, Hadassah Medical Center has over 1,300 beds, 31 operating theaters and nine special intensive care units, and runs five schools of medical professions. History Late Ottoman period (1912–1915) The Hadassah organization was established in 1912 in New York City to provide heal ...
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Bone Marrow Aplasia
Aplastic anemia is a cancer in which the body fails to make blood cells in sufficient numbers. Blood cells are produced in the bone marrow by stem cells that reside there. Aplastic anemia causes a deficiency of all blood cell types: red blood cells, white blood cells, and platelets. It occurs most frequently in people in their teens and twenties but is also common among the elderly. It can be caused by heredity, immune disease, or exposure to chemicals, drugs, or radiation. However, in about half of cases, the cause is unknown. Aplastic anemia can be definitively diagnosed by bone marrow biopsy. Normal bone marrow has 30–70% blood stem cells, but in aplastic anemia, these cells are mostly gone and are replaced by fat. First-line treatment for aplastic anemia consists of immunosuppressive drugs—typically either anti-lymphocyte globulin or anti-thymocyte globulin—combined with corticosteroids, chemotherapy, and ciclosporin. Hematopoietic stem cell transplantation is also u ...
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