Plasmodium Cynomolgi
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Plasmodium Cynomolgi
''Plasmodium cynomolgi'' is an apicomplexan parasite that infects mosquitoes and Asian Old World monkeys. In recent years, a number of natural infections of humans have also been documented. This species has been used as a model for human ''Plasmodium vivax'' because ''Plasmodium cynomolgi'' shares the same life cycle and some important biological features with '' P. vivax''. Life cycle The life cycle of ''P. cynomolgi'' resembles that of other ''Plasmodium'' species, particularly the related human parasite ''Plasmodium vivax''. Like other ''Plasmodium'' species, ''P. cynomolgi'' infects both an insect host and a vertebrate (generally Old World monkeys). The parasite is transmitted when the mosquito host takes a blood meal from the vertebrate host. During the feeding, motile parasites called sporozoites are injected from the mosquito salivary gland into the host tissue. These sporozoites move into the bloodstream and infect cells in the host liver, where they grow and divide ...
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Apicomplexan
The Apicomplexa (also called Apicomplexia) are a large phylum of parasitic alveolates. Most of them possess a unique form of organelle that comprises a type of non-photosynthetic plastid called an apicoplast, and an apical complex structure. The organelle is an adaptation that the apicomplexan applies in penetration of a host cell. The Apicomplexa are unicellular and spore-forming. All species are obligate endoparasites of animals, except '' Nephromyces'', a symbiont in marine animals, originally classified as a chytrid fungus. Motile structures such as flagella or pseudopods are present only in certain gamete stages. The Apicomplexa are a diverse group that includes organisms such as the coccidia, gregarines, piroplasms, haemogregarines, and plasmodia. Diseases caused by Apicomplexa include: * Babesiosis (''Babesia'') * Malaria (''Plasmodium'') * Cryptosporidiosis (''Cryptosporidium parvum'') * Cyclosporiasis (''Cyclospora cayetanensis'') * Cystoisosporiasis (''Cystoisospora ...
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Schüffner's Dots
Schüffner's dots refers to a hematological finding that is associated with malaria, exclusively found in infections caused by ''Plasmodium ovale'' or ''Plasmodium vivax''. ''Plasmodium vivax'' induces morphologic alterations in infected host erythrocytes Red blood cells (RBCs), also referred to as red cells, red blood corpuscles (in humans or other animals not having nucleus in red blood cells), haematids, erythroid cells or erythrocytes (from Greek ''erythros'' for "red" and ''kytos'' for "holl ... that are visible by light microscopy in Romanowsky-stained blood smears as multiple brick-red dots. These morphologic changes, referred to as Schüffner's dots, are important in the identification of this species of malarial parasite and have been associated by electron microscopy with caveolavesicle complexes along the erythrocyte plasmalemma. They are named for Wilhelm Schüffner, who described them in 1904. References External links * http://pathmicro.med.sc.edu/parasito ...
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Antimalarial
Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women. As of 2018, modern treatments, including for severe malaria, continued to depend on therapies deriving historically from quinine and artesunate, both parenteral (injectable) drugs, expanding from there into the many classes of available modern drugs. Incidence and distribution of the disease ("malaria burden") is expected to remain high, globally, for many years to come; moreover, known antimalarial drugs have repeatedly been observed to elicit resistance in the malaria parasite—including for combination therapies featuring artemisinin, a drug of last resort, where resistance has now been observed in Southeast Asia. As such, the needs for new antimalarial agents and new strategies of treatment (e.g., new combin ...
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Thrombocytopenia
Thrombocytopenia is a condition characterized by abnormally low levels of platelets, also known as thrombocytes, in the blood. It is the most common coagulation disorder among intensive care patients and is seen in a fifth of medical patients and a third of surgical patients. A normal human platelet count ranges from 150,000 to 450,000 platelets/microliter (μl) of blood. Values outside this range do not necessarily indicate disease. One common definition of thrombocytopenia requiring emergency treatment is a platelet count below 50,000/μl. Thrombocytopenia can be contrasted with the conditions associated with an abnormally ''high'' level of platelets in the blood - thrombocythemia (when the cause is unknown), and thrombocytosis (when the cause is known). Signs and symptoms Thrombocytopenia usually has no symptoms and is picked up on a routine complete blood count. Some individuals with thrombocytopenia may experience external bleeding, such as nosebleeds or bleeding gums. S ...
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Anemia
Anemia or anaemia (British English) is a blood disorder in which the blood has a reduced ability to carry oxygen due to a lower than normal number of red blood cells, or a reduction in the amount of hemoglobin. When anemia comes on slowly, the symptoms are often vague, such as tiredness, weakness, shortness of breath, headaches, and a reduced ability to exercise. When anemia is acute, symptoms may include confusion, feeling like one is going to pass out, loss of consciousness, and increased thirst. Anemia must be significant before a person becomes noticeably pale. Symptoms of anemia depend on how quickly hemoglobin decreases. Additional symptoms may occur depending on the underlying cause. Preoperative anemia can increase the risk of needing a blood transfusion following surgery. Anemia can be temporary or long term and can range from mild to severe. Anemia can be caused by blood loss, decreased red blood cell production, and increased red blood cell breakdown. Causes o ...
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Rhesus Monkey
The rhesus macaque (''Macaca mulatta''), colloquially rhesus monkey, is a species of Old World monkey. There are between six and nine recognised subspecies that are split between two groups, the Chinese-derived and the Indian-derived. Generally brown or grey in colour, it is in length with a tail and weighs . It is native to South, Central, and Southeast Asia and has the widest geographic range of all non-human primates, occupying a great diversity of altitudes and a great variety of habitats, from grasslands to arid and forested areas, but also close to human settlements. Feral colonies are found in the United States, thought to be either released by humans or escapees after hurricanes destroyed zoo and wildlife park facilities. The rhesus macaque is diurnal, arboreal, and terrestrial. It is mostly herbivorous, mainly eating fruit, but will also consume seeds, roots, buds, bark, and cereals. Studies show almost 100 different plant species in its diet. Rhesus macaques are gener ...
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Semnopithecus Entellus
The northern plains gray langur (''Semnopithecus entellus''), also known as the sacred langur, Bengal sacred langur and Hanuman langur, is a species of primate in the family Cercopithecidae. Taxonomy The northern plains gray langur belongs to the genus ''Semnopithecus'' along with the other Indian langurs. The southern plains gray langur was once classified as a subspecies of ''S. entellus'', i.e., ''S. entellus dussumieri'' and later regarded as a separate species, i.e., ''S. dussumieri'', but is now regarded as an invalid taxon. Most of the specimens that had been regarded as ''Semnopithecus dussumieri'' fall within the revised range of ''Semnopithecus entellus''. Description The fur of adults is mostly light colored, with darker fur on the back and limbs, and the face, ears, hands and feet are all black. Infants are brown. Body size excluding tail ranges from to long, and the tail length is between and . Adult males weigh between and while adult females weigh between ...
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Trachypithecus Cristatus
The silvery lutung (''Trachypithecus cristatus''), also known as the silvered leaf monkey or the silvery langur, is an Old World monkey. It is arboreal, living in coastal, mangrove, and riverine forests in Peninsular Malaysia, Sumatra, and Borneo. It is the type of its species group. Description The silvery lutung is a medium-sized monkey with a long, non-prehensile tail. It has grey-tipped, dark brown or black fur, giving it a uniform silvery appearance. Unlike some related species, there are no paler markings on the face or body, except for a patch of whitish hair on the groin of females. A crest of fur runs along the top of the head, and the hair on the cheeks is long, often obscuring the ears. The hands and feet are hairless, with dark coloured skin, and have opposable thumbs and toes. Females range from in head-body length, with an average weight of and a tail length of . Males are slightly larger, from in length, with an average weight of and a tail length of . Li ...
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Macaca Sinica
The toque macaque (; ''Macaca sinica'') is a reddish-brown-coloured Old World monkey endemic to Sri Lanka, where it is known as the ''rilewa'' or ''rilawa'' ( Sinhala: රිළවා), (hence "rillow" in the ''Oxford English Dictionary''). Its name refers to the whorl of hair at the crown of the head, reminiscent of a brimless toque cap. Taxonomy The generic name ''Macaca'' is from Portuguese ''macaco'', of unclear origin, while ''sinica'' means "of China," even though the species is not found there. There are three recognized subspecies of toque macaques: * ''Macaca sinica sinica'', dry zone toque macaque or common toque macaque * ''Macaca sinica aurifrons'', wet zone toque macaque or pale-fronted toque macaque * ''Macaca sinica opisthomelas'', highland toque macaque or hill zone toque macaque ''M. s. opisthomelas'' is similar to subsp. ''aurifrons'', but has a long fur and contrasting golden color in the anterior part of its brown cap. The three subspecies can be identified ...
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Macaca Radiata
The bonnet macaque (''Macaca radiata''), also known as zati,Chambers English Dictionary is a species of macaque endemic to southern India. Its distribution is limited by the Indian Ocean on three sides and the Godavari and Tapti Rivers, along with its related competitor the rhesus macaque in the north. Land use changes in the last few decades have resulted in changes in its distribution boundaries with the rhesus macaque, raising concern for its status in the wild. The bonnet macaque is diurnal, arboreal, and terrestrial. Males have a head-body length of with a tail while females are with a tail. Males weigh and females . It can live up to 35 years in captivity. The bonnet macaque feeds on fruits, nuts, seeds, flowers, invertebrates, and cereals. In southern India, this macaque exists as commensal to humans, feeding on food given by humans and raiding crops and houses. Taxonomy Two subspecies of bonnet macaques have been identified: *''Macaca radiata radiata'', pale-be ...
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Macaca Nemestrina
The southern pig-tailed macaque (''Macaca nemestrina''), also known as the Sundaland pig-tailed macaque and Sunda pig-tailed macaque, is a medium-sized macaque that lives in southern Thailand, Malaysia, and Indonesia. It is known locally as berok. Etymology and taxonomy The species epithet, ''nemestrina'', is an adjective (derived from Latin ''Nemestrinus'', meaning "the god of groves") modified to agree in gender with the feminine generic name. ''M. nemestrina'' formerly included the northern pig-tailed, Pagai Island, and Siberut macaques as subspecies. All four are now considered separate species. Description As with other ''Macaca'' species, males are larger than females; while males are measured at in length and in weight, females are measured at in length and in weight. This macaque has buff-brown fur, with a darker dorsal area and lighter ventral area. Its common name refers to the short tail held semi-erect, resembling the tail of a pig. Behaviour and e ...
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Macaca Mulatta
The rhesus macaque (''Macaca mulatta''), colloquially rhesus monkey, is a species of Old World monkey. There are between six and nine recognised subspecies that are split between two groups, the Chinese-derived and the Indian-derived. Generally brown or grey in colour, it is in length with a tail and weighs . It is native to South, Central, and Southeast Asia and has the widest geographic range of all non-human primates, occupying a great diversity of altitudes and a great variety of habitats, from grasslands to arid and forested areas, but also close to human settlements. Feral colonies are found in the United States, thought to be either released by humans or escapees after hurricanes destroyed zoo and wildlife park facilities. The rhesus macaque is diurnal, arboreal, and terrestrial. It is mostly herbivorous, mainly eating fruit, but will also consume seeds, roots, buds, bark, and cereals. Studies show almost 100 different plant species in its diet. Rhesus macaques are gener ...
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