Plasmodium Billbrayi
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Plasmodium Billbrayi
''Plasmodium billbrayi'' is a parasite of the genus ''Plasmodium'' subgenus ''Laverania''. ''P. billbrayi'' is phylogenetically very close to ''Plasmodium gaboni'', with both sharing a recent common ancestor. The parasite is named in honour of the distinguished malariologist “Bill” Robert Stow Bray (1923–2008). Taxonomy ''Plasmodium billbrayi'' was first described along with '' Plasmodium billcollinsi'' by Krief ''et al.'' in February 2010, by sequencing the whole ''Plasmodium'' mitochondrial genome in chimpanzees. Distribution This species is found in East Africa. Hosts ''Plasmodium billbrayi'' infects common chimpanzees (''Pan troglodytes'') and Eastern chimpanzee The eastern chimpanzee (''Pan troglodytes schweinfurthii'') is a subspecies of the common chimpanzee. It is native to the Central African Republic, South Sudan, the Democratic Republic of the Congo, Uganda, Rwanda, Burundi, and Tanzania. Taxono ...s (''Pan troglodytes schweinfurthii''). See al ...
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Plasmodium
''Plasmodium'' is a genus of unicellular eukaryotes that are obligate parasites of vertebrates and insects. The life cycles of ''Plasmodium'' species involve development in a blood-feeding insect host which then injects parasites into a vertebrate host during a blood meal. Parasites grow within a vertebrate body tissue (often the liver) before entering the bloodstream to infect red blood cells. The ensuing destruction of host red blood cells can result in malaria. During this infection, some parasites are picked up by a blood-feeding insect (mosquitoes in majority cases), continuing the life cycle. ''Plasmodium'' is a member of the phylum Apicomplexa, a large group of parasitic eukaryotes. Within Apicomplexa, ''Plasmodium'' is in the order Haemosporida and family Plasmodiidae. Over 200 species of ''Plasmodium'' have been described, many of which have been subdivided into 14 subgenera based on parasite morphology and host range. Evolutionary relationships among different ''Pl ...
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Laverania
''Laverania'' is a subgenus of the parasite genus ''Plasmodium''. Infection with these species results in malaria. The subgenus was first described in 1958. The name was first proposed by Welch in 1897 as a genus name for the group now known as ''Plasmodium'' but for a variety of reasons the genus name ''Plasmodium'' was preferred. __TOC__ Taxonomy The first non-human primate parasites were described by Eduard Reichenow in Cameroon in 1920. He observed three morphologically distinct ''Plasmodium'' parasites in the blood of chimpanzees and gorillas in 1917. These finding were later confirmed by other workers. One species closely resembled ''P. falciparum'' and was thought to be the same species. This species was later renamed ''P. reichenowi''. The other two species — ''P. rhodaini'' and ''P. schwetzi'' — have since been placed in the subgenus ''Plasmodium''. The noticeable differences between ''P. falciparum'' and the other known ''Plasmodium'' species led to the proposa ...
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Phylogenetics
In biology, phylogenetics (; from Greek language, Greek wikt:φυλή, φυλή/wikt:φῦλον, φῦλον [] "tribe, clan, race", and wikt:γενετικός, γενετικός [] "origin, source, birth") is the study of the evolutionary history and relationships among or within groups of organisms. These relationships are determined by Computational phylogenetics, phylogenetic inference methods that focus on observed heritable traits, such as DNA sequences, Protein, protein Amino acid, amino acid sequences, or Morphology (biology), morphology. The result of such an analysis is a phylogenetic tree—a diagram containing a hypothesis of relationships that reflects the evolutionary history of a group of organisms. The tips of a phylogenetic tree can be living taxa or fossils, and represent the "end" or the present time in an evolutionary lineage. A phylogenetic diagram can be rooted or unrooted. A rooted tree diagram indicates the hypothetical common ancestor of the tree. An un ...
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Plasmodium Gaboni
''Plasmodium gaboni'' is a parasite of the genus ''Plasmodium'' subgenus ''Laverania''. ''P. gaboni'' was given its name in reference to Gabon, where the parasite was discovered in two wild-borne chimpanzees kept as pets in villages in that country. ''Plasmodium gaboni'' is phylogenetically very close to '' Plasmodium billbrayi''. Taxonomy In 2009, Ollomo et al. published the complete mitochondrial genome of ''Plasmodium gaboni'', which was not yet named at the time. The parasite belongs to the '' P falciparum/ P reichenowi'' lineage. It has been proposed that ''Plasmodium gaboni'' diverged from the ''P falciparum/P reichenowi'' lineage about 21 million years ago, leading to the conclusion that the ancestor of this parasite clade could have been already present in hominid ancestors. ''Plasmodium gaboni'' is 10-fold more diverse than human parasite '' Plasmodium falciparum'', indicating a very recent origin of the latter. ''Plasmodium gaboni'' is similar to both ''Plasmod ...
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Plasmodium Billcollinsi
''Plasmodium billcollinsi'' is a species of the genus ''Plasmodium'' subgenus ''Laverania''. It is a parasitic protozoan found in chimpanzees in Central Africa. The parasite is named in honour of the malariologist William E. Collins. Taxonomy Both ''P. billcollinsi'' and ''P. billbrayi'' were suggested based on mtDNA and nuclear gene sequences, in addition to having been obtained from chimpanzee samples. ''Plasmodium billcollinsi'' is located at the root between '' P. falciparum'' and '' P. reichenowi''. Distribution Analysis made on 1,261 samples revealed that at least six ''Plasmodium'' species circulate in great apes in Gabon, with ''P. billcollinsi'' being found faecal samples from 791 chimpanzees. Hosts Along with '' P. reichenowi'', '' P. billbrayi'' and '' P. gaboni'', ''P. billcollinsi'' infects with malaria to only chimpanzees. The parasite has been found in at least three subspecies: '' P. t. verus'', '' P. t. troglodytes'', and '' P. t. schweinfurthii''. S ...
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Mitochondrial Genome
Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, such as adenosine triphosphate (ATP). Mitochondrial DNA is only a small portion of the DNA in a eukaryotic cell; most of the DNA can be found in the cell nucleus and, in plants and algae, also in plastids such as chloroplasts. Human mitochondrial DNA was the first significant part of the human genome to be sequenced. This sequencing revealed that the human mtDNA includes 16,569 base pairs and encodes 13 proteins. Since animal mtDNA evolves faster than nuclear genetic markers, it represents a mainstay of phylogenetics and evolutionary biology. It also permits an examination of the relatedness of populations, and so has become important in anthropology and biogeography. Origin Nuclear and mitochondrial DNA are thought to be of separate evolutionary origin, with the mtDNA being derived ...
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Common Chimpanzees
The chimpanzee (''Pan troglodytes''), also known as simply the chimp, is a species of great ape native to the forest and savannah of tropical Africa. It has four confirmed subspecies and a fifth proposed subspecies. When its close relative the bonobo was more commonly known as the pygmy chimpanzee, this species was often called the common chimpanzee or the robust chimpanzee. The chimpanzee and the bonobo are the only species in the genus ''Pan''. Evidence from fossils and DNA sequencing shows that ''Pan'' is a sister taxon to the human lineage and is humans' closest living relative. The chimpanzee is covered in coarse black hair, but has a bare face, fingers, toes, palms of the hands, and soles of the feet. It is larger and more robust than the bonobo, weighing for males and for females and standing . The chimpanzee lives in groups that range in size from 15 to 150 members, although individuals travel and forage in much smaller groups during the day. The species lives in ...
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Eastern Chimpanzee
The eastern chimpanzee (''Pan troglodytes schweinfurthii'') is a subspecies of the common chimpanzee. It is native to the Central African Republic, South Sudan, the Democratic Republic of the Congo, Uganda, Rwanda, Burundi, and Tanzania. Taxonomy Though it is formally classified as ''P. t. schweinfurthii'', Colin Groves of the Australian National University argues that there is enough variation between the northern and southern populations of this population of chimpanzees to be split into two subspecies instead of one; the northern population as ''P. t. schweinfurthii'' and the southern population as ''P. t. marungensis''. Threats and conservation The 2007 IUCN Red List classified them as Endangered. Although the common chimpanzee is the most abundant and widespread of the non-human great apes, recent declines in East Africa are expected to continue due to hunting and loss of habitat. Because chimpanzees and humans are physiologically very similar, chimpanzees succumb to many d ...
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List Of Plasmodium Species Infecting Primates
The ''Plasmodium'' species infecting primates include the parasites causing malaria in humans. Species infecting humans Common infections *'' Plasmodium falciparum'' (the cause of malignant tertian malaria) *''Plasmodium vivax'' (the most frequent cause of benign tertian malaria) *''Plasmodium ovale curtisi'' (another, less frequent, cause of benign tertian malaria) *''Plasmodium ovale wallikeri'' (another, less frequent, cause of benign tertian malaria) *''Plasmodium malariae'' (the cause of benign quartan malaria) *''Plasmodium knowlesi'' (the cause of severe quotidian malaria in Southeast Asia) Rare cases While infection of humans by other species is known, they are quite rare, in some instances, only a single case. In a number of the cases, the means of infection is unknown, and may be due to accident, i.e. infection by laboratory equipment or a bite by an animal. With the use of the polymerase chain reaction additional species have been and are still being identifie ...
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