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Pierre Eugène Ménétrier
Pierre Eugène Ménétrier (7 December 1859 – 22 August 1935) was a French pathologist from Paris. He is remembered for his description of a rare gastric disorder that was later to become known as Ménétrier's disease. In 1888 Ménétrier first described the disorder while performing post-mortem studies, noticing hyperplastic changes of the gastric mucosa in cadavers. At the time, he named the disease ''polyadenomes en nappe''. Although Ménétrier understood the debilitative factors of the disease, it wouldn't be until years later that the associated protein-losing enteropathic aspects of the disorder were realized. Other names for "Ménétrier's disease" are "hyperplastic hypersecretory gastropathy" and "giant hypertrophic gastritis". He published his findings in a treatise titled ''Des polyadenomes gastriques et de leurs rapports avec le cancer de l’estomac''. Ménétrier published writings on Byzantine and Greco-Roman medicine, and was a member of the International S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pathologist
Pathology is the study of the causal, causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a narrower fashion to refer to processes and tests that fall within the contemporary medical field of "general pathology", an area which includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue (biology), tissue, human cell, cell, and body fluid samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases (as in the statement "the many different forms of cancer have diverse pathologies", in which case a more proper choice of word would be "Pathophysiology, pathophysiologies"), and the affix ''pathy'' is sometimes used to indicate a state of disease ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paris
Paris () is the capital and most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), making it the 30th most densely populated city in the world in 2020. Since the 17th century, Paris has been one of the world's major centres of finance, diplomacy, commerce, fashion, gastronomy, and science. For its leading role in the arts and sciences, as well as its very early system of street lighting, in the 19th century it became known as "the City of Light". Like London, prior to the Second World War, it was also sometimes called the capital of the world. The City of Paris is the centre of the Île-de-France region, or Paris Region, with an estimated population of 12,262,544 in 2019, or about 19% of the population of France, making the region France's primate city. The Paris Region had a GDP of €739 billion ($743 billion) in 2019, which is the highest in Europe. According to the Economist Intelli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ménétrier's Disease
Ménétrier disease is a rare, acquired, premalignant disease of the stomach characterized by massive gastric folds, excessive mucous production with resultant protein loss, and little or no acid production. The disorder is associated with excessive secretion of transforming growth factor alpha (TGF-α). It is named after a French physician Pierre Eugène Ménétrier, 1859–1935. Signs and symptoms Individuals with the disease present with upper abdominal pain (epigastric), at times accompanied by nausea, vomiting, loss of appetite, edema, weakness, and weight loss. A small amount of gastrointestinal bleeding may occur, which is typically due to superficial mucosal erosions; large volume bleeding is rare. 20% to 100% of patients, depending on time of presentation, develop a protein-losing gastropathy accompanied by low blood albumin and edema. Symptoms and pathological features of Ménétrier disease in children are similar to those in adults, but disease in children is usu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hyperplasia
Hyperplasia (from ancient Greek ὑπέρ ''huper'' 'over' + πλάσις ''plasis'' 'formation'), or hypergenesis, is an enlargement of an organ or tissue caused by an increase in the amount of organic tissue that results from cell proliferation. It may lead to the gross enlargement of an organ, and the term is sometimes confused with benign neoplasia or benign tumor. Hyperplasia is a common preneoplastic response to stimulus. Microscopically, cells resemble normal cells but are increased in numbers. Sometimes cells may also be increased in size (hypertrophy). Hyperplasia is different from hypertrophy in that the adaptive cell change in hypertrophy is an increase in the ''size'' of cells, whereas hyperplasia involves an increase in the ''number'' of cells. Causes Hyperplasia may be due to any number of causes, including proliferation of basal layer of epidermis to compensate skin loss, chronic inflammatory response, hormonal dysfunctions, or compensation for damage o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gastric Mucosa
The gastric mucosa is the mucous membrane layer of the stomach, which contains the glands and the gastric pits. In humans, it is about 1 mm thick, and its surface is smooth, soft, and velvety. It consists of simple columnar epithelium, lamina propria, and the muscularis mucosae. Description In its fresh state, it is of a pinkish tinge at the pyloric end and of a red or reddish-brown color over the rest of its surface. In infancy it is of a brighter hue, the vascular redness being more marked. It is thin at the cardiac extremity, but thicker toward the pylorus. During the contracted state of the organ it is thrown into numerous plaits or rugae, which, for the most part, have a longitudinal direction, and are most marked toward the pyloric end of the stomach, and along the greater curvature. These folds are entirely obliterated when the organ becomes distended. When examined with a lens, the inner surface of the mucous membrane presents a peculiar honeycomb appearance fro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cadaver
A cadaver or corpse is a dead human body that is used by medical students, physicians and other scientists to study anatomy, identify disease sites, determine causes of death, and provide tissue to repair a defect in a living human being. Students in medical school study and dissect cadavers as a part of their education. Others who study cadavers include archaeologists and arts students. The term ''cadaver'' is used in courts of law (and, to a lesser extent, also by media outlets such as newspapers) to refer to a dead body, as well as by recovery teams searching for bodies in natural disasters. The word comes from the Latin word ''cadere'' ("to fall"). Related terms include ''cadaverous'' (resembling a cadaver) and ''cadaveric spasm'' (a muscle spasm causing a dead body to twitch or jerk). A cadaver graft (also called “postmortem graft”) is the grafting of tissue from a dead body onto a living human to repair a defect or disfigurement. Cadavers can be observed for their sta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Losing Enteropathy
Protein losing enteropathy refers to any condition of the gastrointestinal tract (e.g. damage to the gut wall) that results in a net loss of protein from the body. Signs and symptoms The signs/symptoms of protein losing enteropathy are consistent with diarrhea, fever, and general abdominal discomfort. Swelling of the legs due to peripheral edema can also occur, however, if the PLE is related to a systemic disease such as congestive heart failure or constrictive pericarditis, then the symptoms could be of the primary disease development. Causes The causes of protein-losing enteropathy can include GI conditions (among other causes), like the following: Mechanism The pathophysiology of protein losing enteropathy is a result of plasma proteins loss, which enters GI tract ( lumen). PLE is a complication of a disorder, be it lymphatic obstruction or mucosal injury. In ''pediatric protein losing enteropathy'' there are several changes in epithelial cells causing PLE by augmenting the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gastritis
Gastritis is inflammation of the lining of the stomach. It may occur as a short episode or may be of a long duration. There may be no symptoms but, when symptoms are present, the most common is upper abdominal pain (see dyspepsia). Other possible symptoms include nausea and vomiting, bloating, loss of appetite and heartburn. Complications may include stomach bleeding, stomach ulcers, and stomach tumors. When due to autoimmune problems, low red blood cells due to not enough vitamin B12 may occur, a condition known as pernicious anemia. Common causes include infection with '' Helicobacter pylori'' and use of nonsteroidal anti-inflammatory drugs ( NSAIDs). Less common causes include alcohol, smoking, cocaine, severe illness, autoimmune problems, radiation therapy and Crohn's disease. Endoscopy, a type of X-ray known as an upper gastrointestinal series, blood tests, and stool tests may help with diagnosis. The symptoms of gastritis may be a presentation of a myocardial infarcti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Byzantine Medicine
Byzantine medicine encompasses the common medical practices of the Byzantine Empire from c. 400 AD to 1453 AD. Byzantine medicine was notable for building upon the knowledge base developed by its Greco-Roman predecessors. In preserving medical practices from antiquity, Byzantine medicine influenced Islamic medicine and fostered the Western rebirth of medicine during the Renaissance. Byzantine physicians often compiled and standardized medical knowledge into textbooks. Their records tended to include both diagnostic explanations and technical drawings. The Medical Compendium in Seven Books, written by the leading physician Paul of Aegina, survived as a particularly thorough source of medical knowledge. This compendium, written in the late seventh century, remained in use as a standard textbook for the following 800 years. This tradition of compilation continued from around the tenth century into the twentieth through the genre of medical writings known as ''iatrosophia''. Late ant ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Society For The History Of Medicine
The International Society for the History of Medicine is a non profit international society devoted to the academic study of the history of medicine, including the organization of international congresses. The Society was founded in 1920 in Belgium. The society is present in 50 countries, holds delegations in 38 countries, and has about 800 members. It also includes national societies in Argentina, Belgium, Chile, Finland, France, Greece, Mexico, Morocco, Romania, Turkey, and the United Kingdom. Membership is open to both physicians and historians. International congresses The society holds a biennial International Congress, and, beginning in 2001, an international meeting in the years the main conference is not helSee listCommunications to the international congresses are peer reviewed.Brief of the Globe Foundations,vol 13: " 1990, to the last decade of the Century", pages 10&112009 Edmond Gravenor and the Council of World Organizations, Review of the International Societies a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lisieux
Lisieux () is a commune in the Calvados department in the Normandy region in northwestern France. It is the capital of the Pays d'Auge area, which is characterised by valleys and hedged farmland. Name The name of the town derives from the la, Noviomagus Lexoviorum ("Noviomagus of the Lexovii"). The town was originally known in Celtic as ("New Field", "New Market"), which was Latinized as . Owing to the large number of similarly named cities, however, it was necessary to specify where this one was located. The local French demonym derives from the Latin as well. History Antiquity Lisieux was the capital of the Lexovii. In his work, ''Commentaries on the Gallic War'', Caesar mentions a Gallic ''oppidum'', a term which refers to Celtic towns located on the tops of hills. The oppidum has been pinpointed to a place referred to as ''le Castellier'', located to the southwest of the town. However the Gallo-Roman city was in fact located where Lisieux is to be found today. Midd ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1859 Births
Events January–March * January 21 – José Mariano Salas (1797–1867) becomes Conservative interim President of Mexico. * January 24 ( O. S.) – Wallachia and Moldavia are united under Alexandru Ioan Cuza (Romania since 1866, final unification takes place on December 1, 1918; Transylvania and other regions are still missing at that time). * January 28 – The city of Olympia is incorporated in the Washington Territory of the United States of America. * February 2 – Miguel Miramón (1832–1867) becomes Conservative interim President of Mexico. * February 4 – German scholar Constantin von Tischendorf rediscovers the ''Codex Sinaiticus'', a 4th-century uncial manuscript of the Greek Bible, in Saint Catherine's Monastery on the foot of Mount Sinai, in the Khedivate of Egypt. * February 14 – Oregon is admitted as the 33rd U.S. state. * February 12 – The Mekteb-i Mülkiye School is founded in the Ottoman Empire. * February 17 – French naval forces under Char ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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