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Philippe Grandjean (professor)
Philippe Grandjean (born 1 March 1950) is a Danish scientist working in environmental medicine. He is the head of the Environmental Medicine Research Unit at the University of Southern Denmark and adjunct professor of environmental health at the Harvard School of Public Health. Grandjean is also co-founder and co-editor-in-chief of the journal ''Environmental Health'', and consultant for the National Board of Health in Denmark. He is known for his research into the developmental toxicity and adverse effects of certain environmental chemicals to which children are commonly exposed. Life, education and career Born in Denmark in 1950, his interest in environmental toxins began as a teenager watching birds and realizing that they were threatened by pesticides. Grandjean obtained his MD in environmental medicine from the University of Copenhagen in 1974 and his PhD in 1979. He began his career conducting field work into mercury poisoning and Minamata disease after seeing a woman wit ...
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Denmark
) , song = ( en, "King Christian stood by the lofty mast") , song_type = National and royal anthem , image_map = EU-Denmark.svg , map_caption = , subdivision_type = Sovereign state , subdivision_name = Kingdom of Denmark , established_title = Consolidation , established_date = 8th century , established_title2 = Christianization , established_date2 = 965 , established_title3 = , established_date3 = 5 June 1849 , established_title4 = Faroese home rule , established_date4 = 24 March 1948 , established_title5 = EEC accession , established_date5 = 1 January 1973 , established_title6 = Greenlandic home rule , established_date6 = 1 May 1979 , official_languages = Danish , languages_type = Regional languages , languages_sub = yes , languages = GermanGerman is recognised as a protected minority language in the South Jutland area of Denmark. , demonym = , capital = Copenhagen , largest_city = capital , coordinates = , ethnic_groups = , ethnic_g ...
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Boston University
Boston University (BU) is a Private university, private research university in Boston, Massachusetts. The university is nonsectarian, but has a historical affiliation with the United Methodist Church. It was founded in 1839 by Methodists with its original campus in Newbury (town), Vermont, Newbury, Vermont, before moving to Boston in 1867. The university now has more than 4,000 faculty members and nearly 34,000 students, and is one of Boston's largest employers. It offers bachelor's degrees, master's degrees, doctorates, and medical, dental, business, and law degrees through 17 schools and colleges on three urban campuses. The main campus is situated along the Charles River in Boston's Fenway-Kenmore and Allston, Massachusetts, Allston neighborhoods, while the Boston University Medical Campus is located in Boston's South End, Boston, South End neighborhood. The Fenway campus houses the Wheelock College of Education and Human Development, formerly Wheelock College, which merged ...
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1950 Births
Year 195 ( CXCV) was a common year starting on Wednesday (link will display the full calendar) of the Julian calendar The Julian calendar, proposed by Roman consul Julius Caesar in 46 BC, was a reform of the Roman calendar. It took effect on , by edict. It was designed with the aid of Greek mathematicians and astronomers such as Sosigenes of Alexandr .... At the time, it was known as the Year of the Consulship of Scrapula and Clemens (or, less frequently, year 948 '' Ab urbe condita''). The denomination 195 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Emperor Septimius Severus has the Roman Senate deify the previous emperor Commodus, in an attempt to gain favor with the family of Marcus Aurelius. * King Vologases V and other eastern princes support the claims of Pescennius Niger. The Roman province of Mesopotamia ...
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The Atlantic
''The Atlantic'' is an American magazine and multi-platform publisher. It features articles in the fields of politics, foreign affairs, business and the economy, culture and the arts, technology, and science. It was founded in 1857 in Boston, as ''The Atlantic Monthly'', a literary and cultural magazine that published leading writers' commentary on education, the abolition of slavery, and other major political issues of that time. Its founders included Francis H. Underwood and prominent writers Ralph Waldo Emerson, Oliver Wendell Holmes Sr., Henry Wadsworth Longfellow, Harriet Beecher Stowe, and John Greenleaf Whittier. James Russell Lowell was its first editor. In addition, ''The Atlantic Monthly Almanac'' was an annual almanac published for ''Atlantic Monthly'' readers during the 19th and 20th centuries. A change of name was not officially announced when the format first changed from a strict monthly (appearing 12 times a year) to a slightly lower frequency. It was a mo ...
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CBS News
CBS News is the news division of the American television and radio service CBS. CBS News television programs include the '' CBS Evening News'', '' CBS Mornings'', news magazine programs '' CBS News Sunday Morning'', '' 60 Minutes'', and '' 48 Hours'', and Sunday morning political affairs program '' Face the Nation''. CBS News Radio produces hourly newscasts for hundreds of radio stations, and also oversees CBS News podcasts like '' The Takeout Podcast''. CBS News also operates a 24-hour digital news network. Up until April 2021, the president and senior executive producer of CBS News was Susan Zirinsky, who assumed the role on March 1, 2019. Zirinsky, the first female president of the network's news division, was announced as the choice to replace David Rhodes on January 6, 2019. The announcement came amid news that Rhodes would step down as president of CBS News "amid falling ratings and the fallout from revelations from an investigation into sexual misconduct allegatio ...
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Neurodevelopment
The development of the nervous system in humans, or neural development or neurodevelopment involves the studies of embryology, developmental biology, and neuroscience to describe the cellular and molecular mechanisms by which the complex nervous system forms in humans, develops during prenatal development, and continues to develop postnatally. Some landmarks of neural development in the embryo include the formation and differentiation of neurons from stem cell precursors (neurogenesis); the migration of immature neurons from their birthplaces in the embryo to their final positions; the outgrowth of axons from neurons and guidance of the motile growth cone through the embryo towards postsynaptic partners, the generation of synapses between these axons and their postsynaptic partners, the synaptic pruning that occurs in adolescence, and finally the lifelong changes in synapses which are thought to underlie learning and memory. Typically, these neurodevelopmental processes can b ...
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Toluene Toxicity
Toluene toxicity refers to the harmful effects caused by toluene on the body. Metabolism in humans While a significant amount of toluene, 25%–40%, is exhaled unchanged via the lungs, a greater proportion is metabolised and excreted via other pathways. The primary route of toluene metabolism is by hydroxylation to benzyl alcohol by members of the cytochrome P450 (CYP) superfamily. There are five CYPs which are important in toluene metabolism, CYP1A2, CYP2B6, CYP2E1, CYP2C8, and CYP1A1. The first four seem to be involved in the hydroxylation of toluene to benzyl alcohol. CYP2E1 seems to be the primary enzyme in the hydroxylation of toluene, accounting for roughly 44% of toluene metabolism; however, there is a great deal of ethnic variability, in the Finnish population for example the primary enzyme is CYP2B6. CYP2E1 catalyses the formation of benzyl alcohol and p-cresol, while CYP2B6 produces comparatively little p-cresol. It is believed that in humans, benzyl alcohol is metabo ...
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Polychlorinated Biphenyl
Polychlorinated biphenyls (PCBs) are highly carcinogenic chemical compounds, formerly used in industrial and consumer products, whose production was banned in the United States by the Toxic Substances Control Act in 1979 and internationally by the Stockholm Convention on Persistent Organic Pollutants in 2001. They are organic chlorine compounds with the formula C12 H10−''x'' Cl''x''; they were once widely used in the manufacture of carbonless copy paper, as heat transfer fluids, and as dielectric and coolant fluids for electrical equipment. Because of their longevity, PCBs are still widely in use, even though their manufacture has declined drastically since the 1960s, when a host of problems were identified. With the discovery of PCBs' environmental toxicity, and classification as persistent organic pollutants, their production was banned by United States federal law in 1978, and by the Stockholm Convention on Persistent Organic Pollutants in 2001. The International Agency ...
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Heavy Metals
upright=1.2, Crystals of osmium, a heavy metal nearly twice as dense as lead">lead.html" ;"title="osmium, a heavy metal nearly twice as dense as lead">osmium, a heavy metal nearly twice as dense as lead Heavy metals are generally defined as metals with relatively high density, densities, atomic weights, or atomic numbers. The criteria used, and whether metalloids are included, vary depending on the author and context. In metallurgy, for example, a heavy metal may be defined on the basis of density, whereas in physics the distinguishing criterion might be atomic number, while a chemist would likely be more concerned with chemical property, chemical behaviour. More specific definitions have been published, but none of these have been widely accepted. The definitions surveyed in this article encompass up to 96 out of the 118 known chemical elements; only mercury, lead and bismuth meet all of them. Despite this lack of agreement, the term (plural or singular) is widely used i ...
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Organofluorine Chemistry
Organofluorine chemistry describes the chemistry of the organofluorines, organic compounds that contain the carbon–fluorine bond. Organofluorine compounds find diverse applications ranging from oil and water repellents to pharmaceuticals, refrigerants, and reagents in catalysis. In addition to these applications, some organofluorine compounds are pollutants because of their contributions to ozone depletion, global warming, bioaccumulation, and toxicity. The area of organofluorine chemistry often requires special techniques associated with the handling of fluorinating agents. The carbon–fluorine bond Fluorine has several distinctive differences from all other substituents encountered in organic molecules. As a result, the physical and chemical properties of organofluorines can be distinctive in comparison to other organohalogens. # The carbon–fluorine bond is one of the strongest in organic chemistry (an average bond energy around 480 kJ/molKirsch, Peer ''Modern f ...
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Philip Landrigan
Philip John Landrigan (born June 14, 1942), is an American epidemiologist and pediatrician and one of the world's leading advocates of children's health. His work has been recognized by national non-profit organization Healthy Child Healthy World (Lifetime Achievement Award) and the U.S. Environmental Protection Agency (Child Health Champion Award), and he is included in New York Magazine's list of "Best Doctors 2008." His books include ''Raising Healthy Children in a Toxic World: 101 Smart Solutions for Every Family'' and, with Herbert Needleman, ''Raising Children Toxic Free: How to Keep Your Child Safe From Lead, Asbestos, Pesticides and Other Environmental Hazards''. He has published over 500 scientific papers. He was formerly the Director of the Children's Environmental Health Center and the Ethel Wise Professor and Chair of the Department of Preventive Medicine at Mount Sinai Medical Center in New York City. In 2018 he became the founding director of Boston College's Glo ...
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Mercury In Fish
The presence of mercury in fish is a health concern for people who eat them, especially for women who are or may become pregnant, nursing mothers, and young children. Fish and shellfish concentrate mercury in their bodies, often in the form of methylmercury, a highly toxic organomercury compound. This element is known to bioaccumulate in humans, so bioaccumulation in seafood carries over into human populations, where it can result in mercury poisoning. Mercury is dangerous to both natural ecosystems and humans because it is a metal known to be highly toxic, especially due to its neurotoxic ability to damage the central nervous system. In human-controlled ecosystems of fish, usually done for market production of wanted seafood species, mercury clearly rises through the food chain via fish consuming small plankton, as well as through non-food sources such as underwater sediment. Fish products have been shown to contain varying amounts of heavy metals, particularly mercury and ...
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