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Peter Hermann Stillmark
Peter Hermann Stillmark (22 July 1860, Penza, Russia – 23 June 1923, Pärnu, Estonia) was a Baltic-German microbiologist. In 1888 at the University in Dorpat, now Tartu in Estonia under Professor Rudolf Kobert's supervision, Peter Hermann Stillmark (1860–1923) completed his doctoral thesis ''Über Ricin, ein giftiges Ferment aus den Samen von ''Ricinus comm.'' L. und einigen anderen Euphorbiaceen'', which is a description of the isolation of ricin, a poisonous protein component from castor beans. That event is internationally recognised as the birth of a new branch of science called lectinology. Lectins are any of a group of proteins, derived from plants, that can bind to specific oligosaccharides on the surfaces of cells, causing the cells to clump together. They can be used to identify mutant cells in cell cultures and to determine blood groups, as they can cause the agglutination of red blood cells. Lectins are found in seeds of legumes and other tissues, in which they ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Penza
Penza ( rus, Пе́нза, p=ˈpʲɛnzə) is the largest city and administrative center of Penza Oblast, Russia. It is located on the Sura River, southeast of Moscow. As of the 2010 Census, Penza had a population of 517,311, making it the 38th-largest city in Russia. Etymology The city name is a hydronym and means in mdf, Пенза, Penza, end of swampy river () from ''pen'' 'end of (Genetive)' and ''sa(ra)'' 'swampy river' Geography Urban layout This central quarter occupies the territory on which the wooden fortress Penza was once located, therefore it is sometimes called the Serf. The architectural concept of the old fortress, erected on the eastern slope of the mountain above the river, predetermined the direction of the first streets. The direction and location of the first streets were set by the passage towers of the fortress and the orientation of its walls. This is how the first six streets of the city were formed. Subsequently, the names were fixed to them: Governo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lectin
Lectins are carbohydrate-binding proteins that are highly specific for sugar groups that are part of other molecules, so cause agglutination of particular cells or precipitation of glycoconjugates and polysaccharides. Lectins have a role in recognition at the cellular and molecular level and play numerous roles in biological recognition phenomena involving cells, carbohydrates, and proteins. Lectins also mediate attachment and binding of bacteria, viruses, and fungi to their intended targets. Lectins are ubiquitous in nature and are found in many foods. Some foods, such as beans and grains, need to be cooked, fermented or sprouted to reduce lectin content. Some lectins are beneficial, such as CLEC11A, which promotes bone growth, while others may be powerful toxins such as ricin. Lectins may be disabled by specific mono- and oligosaccharides, which bind to ingested lectins from grains, legumes, nightshade plants, and dairy; binding can prevent their attachment to the carbohyd ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Estonian Microbiologists
Estonian may refer to: * Something of, from, or related to Estonia, a country in the Baltic region in northern Europe * Estonians, people from Estonia, or of Estonian descent * Estonian language * Estonian cuisine * Estonian culture See also * * Estonia (other) * Languages of Estonia * List of Estonians This is a list of notable Estonians. Architects *Andres Alver (born 1953) *Dmitri Bruns (1929–2020) *Karl Burman (1882–1965) *Eugen Habermann (1884–1944) *Georg Hellat (1870–1943) *Otto Pius Hippius (1826–1883) * Erich Jacoby (1885–19 ... {{Disambiguation Language and nationality disambiguation pages ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1923 Deaths
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * '' Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album ''Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Sl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1860 Births
Year 186 ( CLXXXVI) was a common year starting on Saturday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Aurelius and Glabrio (or, less frequently, year 939 ''Ab urbe condita''). The denomination 186 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Peasants in Gaul stage an anti-tax uprising under Maternus. * Roman governor Pertinax escapes an assassination attempt, by British usurpers. New Zealand * The Hatepe volcanic eruption extends Lake Taupō and makes skies red across the world. However, recent radiocarbon dating by R. Sparks has put the date at 233 AD ± 13 (95% confidence). Births * Ma Liang, Chinese official of the Shu Han state (d. 222) Deaths * April 21 – Apollonius the Apologist, Christian martyr * Bian Zhang, Chinese official and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GFDL
The GNU Free Documentation License (GNU FDL or simply GFDL) is a copyleft license for free documentation, designed by the Free Software Foundation (FSF) for the GNU Project. It is similar to the GNU General Public License, giving readers the rights to copy, redistribute, and modify (except for "invariant sections") a work and requires all copies and derivatives to be available under the same license. Copies may also be sold commercially, but, if produced in larger quantities (greater than 100), the original document or source code must be made available to the work's recipient. The GFDL was designed for manuals, textbooks, other reference and instructional materials, and documentation which often accompanies GNU software. However, it can be used for any text-based work, regardless of subject matter. For example, the free online encyclopedia Wikipedia uses the GFDL (coupled with the Creative Commons Attribution Share-Alike License) for much of its text, excluding text that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lectin
Lectins are carbohydrate-binding proteins that are highly specific for sugar groups that are part of other molecules, so cause agglutination of particular cells or precipitation of glycoconjugates and polysaccharides. Lectins have a role in recognition at the cellular and molecular level and play numerous roles in biological recognition phenomena involving cells, carbohydrates, and proteins. Lectins also mediate attachment and binding of bacteria, viruses, and fungi to their intended targets. Lectins are ubiquitous in nature and are found in many foods. Some foods, such as beans and grains, need to be cooked, fermented or sprouted to reduce lectin content. Some lectins are beneficial, such as CLEC11A, which promotes bone growth, while others may be powerful toxins such as ricin. Lectins may be disabled by specific mono- and oligosaccharides, which bind to ingested lectins from grains, legumes, nightshade plants, and dairy; binding can prevent their attachment to the carbohyd ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Castor Beans
''Ricinus communis'', the castor bean or castor oil plant, is a species of perennial flowering plant in the Euphorbia, spurge family, Euphorbiaceae. It is the sole species in the monotypic genus, ''Ricinus'', and subtribe, Ricininae. The evolution of castor and its relation to other species are currently being studied using modern genetic tools. It reproduces with a mixed pollination system which favors selfing by geitonogamy but at the same time can be an out-crosser by anemophily (wind pollination) or entomophily (insect pollination). Its seed is the castor bean, which, despite its name, is not a bean (that is, the seed of many Fabaceae). Castor is indigenous to the southeastern Mediterranean Basin, Eastern Africa, and India, but is widespread throughout tropical regions (and widely grown elsewhere as an ornamental plant). Castor seed is the source of castor oil, which has a wide variety of uses. The seeds contain between 40% and 60% oil that is rich in triglycerides, mainly ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ricin
Ricin ( ) is a lectin (a carbohydrate-binding protein) and a highly potent toxin produced in the seeds of the castor oil plant, ''Ricinus communis''. The median lethal dose (LD50) of ricin for mice is around 22 micrograms per kilogram of body weight via intraperitoneal injection. Oral exposure to ricin is far less toxic. An estimated lethal oral dose in humans is approximately 1 milligram per kilogram of body weight. Ricin was first described by Peter Hermann Stillmark, the founder of lectinology. Biochemistry Ricin is classified as a type 2 ribosome-inactivating protein (RIP). Whereas type 1 RIPs are composed of a single protein chain that possesses catalytic activity, type 2 RIPs, also known as holotoxins, are composed of two different protein chains that form a heterodimeric complex. Type 2 RIPs consist of an A chain that is functionally equivalent to a type 1 RIP, covalently connected by a single disulfide bond to a B chain that is catalytically inactive, but se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Russia
Russia (, , ), or the Russian Federation, is a transcontinental country spanning Eastern Europe and Northern Asia. It is the largest country in the world, with its internationally recognised territory covering , and encompassing one-eighth of Earth's inhabitable landmass. Russia extends across eleven time zones and shares land boundaries with fourteen countries, more than any other country but China. It is the world's ninth-most populous country and Europe's most populous country, with a population of 146 million people. The country's capital and largest city is Moscow, the largest city entirely within Europe. Saint Petersburg is Russia's cultural centre and second-largest city. Other major urban areas include Novosibirsk, Yekaterinburg, Nizhny Novgorod, and Kazan. The East Slavs emerged as a recognisable group in Europe between the 3rd and 8th centuries CE. Kievan Rus' arose as a state in the 9th century, and in 988, it adopted Orthodox Christianity from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rudolf Kobert
Rudolf Kobert (3 January 1854 – 27 December 1918) was a German pharmacologist and toxicologist born in Bitterfeld. In 1877 he graduated from the University of Halle, afterwards working as an assistant to physiologist Friedrich Goltz (1834-1902) and pharmacologist Oswald Schmiedeberg (1838–1920) at the University of Strasbourg. In 1887 he was appointed professor of pharmacology, dietetics and history of medicine at the University of Dorpat. One of his students was Peter Hermann Stillmark who was the founder of lectinology with the publication of his thesis about ricin. Due to "Russification" of the university, Kobert left Dorpat in 1896, subsequently becoming director of the ''Brehmerschen Heilanstalten'' (a sanatorium founded decades earlier by Hermann Brehmer) in Gorbersdorf. In 1899 he was appointed to the chair of pharmacology, pharmacognosy, chemistry and physiological history of medicine at the University of Rostock, a position he kept until his death. Kobert's work lar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tartu
Tartu is the second largest city in Estonia after the Northern European country's political and financial capital, Tallinn. Tartu has a population of 91,407 (as of 2021). It is southeast of Tallinn and 245 kilometres (152 miles) northeast of Riga, Latvia. Tartu lies on the Emajõgi river, which connects the two largest lakes in Estonia, Lake Võrtsjärv and Lake Peipus. From the 13th century until the end of the 19th century, Tartu was known in most of the world by variants of its historical name Dorpat. Tartu, the largest urban centre of southern Estonia, is often considered the "intellectual capital city" of the country, especially as it is home to the nation's oldest and most renowned university, the University of Tartu (founded in 1632). Tartu also houses the Supreme Court of Estonia, the Ministry of Education and Research, the Estonian National Museum, and the oldest Estonian-language theatre, Vanemuine. It is also the birthplace of the Estonian Song Festivals ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
