Paul Gerson Unna
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Paul Gerson Unna
Paul Gerson Unna, (September 8, 1850, Hamburg – January 29, 1929, Hamburg) was a German physician specialized in dermatology and one of the pioneers in dermatopathology. Biography Paul Unna was the son of Moritz Adolph Unna, a physician from Hamburg. Unna was educated at the Gelehrtenschule des Johanneums. He began to study medicine at the University of Heidelberg, but had to interrupt it in order to fight in the Franco-Prussian war, where he was severely wounded. In 1871, he resumed his studies in Heidelberg and later went to the University of Leipzig, finally attaining a doctorate under Heinrich Wilhelm Waldeyer in Strasbourg. His doctoral work was on the subject of the histology and development of the epidermis, and was published in 1876. The thesis contained a set of new ideas and aspects that were met with hard criticism. They were accepted only after some corrections were made. He went on to receive his training in dermatology in Vienna, where he worked in cooperation ...
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Paul Gerson Unna
Paul Gerson Unna, (September 8, 1850, Hamburg – January 29, 1929, Hamburg) was a German physician specialized in dermatology and one of the pioneers in dermatopathology. Biography Paul Unna was the son of Moritz Adolph Unna, a physician from Hamburg. Unna was educated at the Gelehrtenschule des Johanneums. He began to study medicine at the University of Heidelberg, but had to interrupt it in order to fight in the Franco-Prussian war, where he was severely wounded. In 1871, he resumed his studies in Heidelberg and later went to the University of Leipzig, finally attaining a doctorate under Heinrich Wilhelm Waldeyer in Strasbourg. His doctoral work was on the subject of the histology and development of the epidermis, and was published in 1876. The thesis contained a set of new ideas and aspects that were met with hard criticism. They were accepted only after some corrections were made. He went on to receive his training in dermatology in Vienna, where he worked in cooperation ...
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Moritz Kaposi
Moritz Kaposi ( hu, Kaposi Mór, ; 23 October 1837 in Kaposvár, Hungary – 6 March 1902 in Vienna, Austria-Hungary) was a Hungarian physician and dermatologist who discovered the skin tumor that received his name (Kaposi's sarcoma). Biography Early life and name Born to a Jewish family, originally his surname was Kohn; but, with his conversion to the Catholic faith, he changed it to Kaposi in 1871, in reference to his town of birth. One purported reason behind this is that he wanted to marry a daughter of current dermatology chairman, Ferdinand Ritter von Hebra, and advance in the society, which he could not have done being of Jewish faith. This seems unlikely because he married Martha Hebra and converted to Catholicism several years prior to changing his name, by which time he was already well established in the Vienna University faculty and a close associate of her father, Ferdinand. A more plausible explanation is based on his own comments to colleagues that he changed his ...
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Sebaceous Follicle
A sebaceous gland is a microscopic exocrine gland in the skin that opens into a hair follicle to secrete an oily or waxy matter, called sebum, which lubricates the hair and skin of mammals. In humans, sebaceous glands occur in the greatest number on the face and scalp, but also on all parts of the skin except the palms of the hands and soles of the feet. In the eyelids, meibomian glands, also called tarsal glands, are a type of sebaceous gland that secrete a special type of sebum into tears. Surrounding the female nipple, areolar glands are specialized sebaceous glands for lubricating the nipple. Fordyce spots are benign, visible, sebaceous glands found usually on the lips, gums and inner cheeks, and genitals. Structure Location Sebaceous glands are found throughout all areas of the skin, except the palms of the hands and soles of the feet. There are two types of sebaceous glands, those connected to hair follicles and those that exist independently. Sebaceous glands are found ...
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Scalp
The scalp is the anatomical area bordered by the human face at the front, and by the neck at the sides and back. Structure The scalp is usually described as having five layers, which can conveniently be remembered as a mnemonic: * S: The skin on the head from which head hair grows. It contains numerous sebaceous glands and hair follicles. * C: Connective tissue. A dense subcutaneous layer of fat and fibrous tissue that lies beneath the skin, containing the nerves and vessels of the scalp. * A: The aponeurosis called epicranial aponeurosis (or galea aponeurotica) is the next layer. It is a tough layer of dense fibrous tissue which runs from the frontalis muscle anteriorly to the occipitalis posteriorly. * L: The loose areolar connective tissue layer provides an easy plane of separation between the upper three layers and the pericranium. In scalping the scalp is torn off through this layer. It also provides a plane of access in craniofacial surgery and neurosurgery. This layer i ...
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Seborrhea
A sebaceous gland is a microscopic exocrine gland in the skin that opens into a hair follicle to secrete an oily or waxy matter, called sebum, which lubricates the hair and skin of mammals. In humans, sebaceous glands occur in the greatest number on the face and scalp, but also on all parts of the skin except the palms of the hands and soles of the feet. In the eyelids, meibomian glands, also called tarsal glands, are a type of sebaceous gland that secrete a special type of sebum into tears. Surrounding the female nipple, areolar glands are specialized sebaceous glands for lubricating the nipple. Fordyce spots are benign, visible, sebaceous glands found usually on the lips, gums and inner cheeks, and genitals. Structure Location Sebaceous glands are found throughout all areas of the skin, except the palms of the hands and soles of the feet. There are two types of sebaceous glands, those connected to hair follicles and those that exist independently. Sebaceous glands are fo ...
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Unna's Disease
Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant, X-linked, and acquired forms have all been described. Types Clinically, three distinct patterns of palmoplantar keratoderma may be identified: diffuse, focal, and punctate. Diffuse Diffuse palmoplantar keratoderma is a type of palmoplantar keratoderma that is characterized by an even, thick, symmetric hyperkeratosis over the whole of the palm and sole, usually evident at birth or in the first few months of life. Restated, diffuse palmoplantar keratoderma is an autosomal dominant disorder in which hyperkeratosis is confined to the palms and soles. The two major types can have a similar clinical appearance: *''Diffuse epidermolytic palmoplantar keratoderma'' (also known as "Palmoplantar keratoderma cum degeneratione granulosa Vörner," "Vörner's epidermolytic palmoplantar keratoderma", and "Vörn ...
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University Of Hamburg
The University of Hamburg (german: link=no, Universität Hamburg, also referred to as UHH) is a public research university in Hamburg, Germany. It was founded on 28 March 1919 by combining the previous General Lecture System ('' Allgemeines Vorlesungswesen''), the Hamburg Colonial Institute ('' Hamburgisches Kolonialinstitut''), and the Academic College ('' Akademisches Gymnasium''). The main campus is located in the central district of Rotherbaum, with affiliated institutes and research centres distributed around the city-state. The university has been ranked in the top 200 universities worldwide by the ''Times Higher Education Ranking'', the Shanghai Ranking and the CWTS Leiden Ranking, placing it among the top 1% of global universities. Seven Nobel Prize winners and one Wolf Prize winner are affiliated with UHH. On a national scale, '' U.S. News & World Report'' ranks UHH 7th and ''QS World University Rankings'' 14th out of a total of 426 German institutions of higher educa ...
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University Medical Center Hamburg-Eppendorf
The University Medical Center Hamburg-Eppendorf (german: Universitätsklinikum Hamburg-Eppendorf (UKE)) is the teaching hospital of the University of Hamburg and the largest hospital in Hamburg, Germany. The UKE has 1,738 beds and 121 day-care places and is listed to provide the capacity to dispatch emergency medical services. History The first parts of the hospital were built between 1884 and 1889. From 1913 until 1926, Fritz Schumacher built a general purpose building, today called ''Fritz-Schumacher-Haus'', among others for the pathological anatomy with a dissecting room. In 2008 the hospital participated in the Tag des offenen Denkmals, a Germany-wide annual event sponsored by the Deutsche Stiftung Denkmalschutz, that opens cultural heritage sites to the public—showing the ''Fritz-Schumacher-Haus'' and the operating theatre in a bunker from World War II. In 2011, the hospital achieved Stage 7 of the Healthcare Information and Management Systems Society Analytics Europ ...
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Eppendorf, Hamburg
Eppendorf is one of thirteen quarters in the Hamburg-Nord borough of Hamburg, Germany, and lies north of the Außenalster. In 2020 the population was 24,806. History Eppendorf, first mentioned as ''Eppenthorp'' in 1140, is Hamburg's oldest village. Its name originates either from the old Germanic ''epen'' (on the water) or from the personal name Ebbo/Eppo. It is possible, but unlikely, that it was named after Ebbo, the archbishop of Reims. During the restoration of the St. Johannis Church, which was first mentioned in 1267, ruins of an older stone tower were found. In the 19th century, Eppendorf gained popularity among the affluent people in Hamburg. The low-lying, moist land was banked up and built on. The last area of moorland, the Eppendorfer Moor, was placed under nature protection in 1982. In 1894, Eppendorf was transferred to Hamburg. Geography In 2007 according to the statistical office of Hamburg and Schleswig-Holstein, the quarter Eppendorf has an area of 2,7 km ...
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Senate Of Hamburg
The government of Hamburg is divided into executive, legislative and judicial branches. Hamburg is a city-state and municipality, and thus its governance deals with several details of both state and local community politics. It takes place in two ranks – a citywide and state administration (Senate of Hamburg), and a local rank for the boroughs. The head of the city-state's government is the First Mayor and President of the Senate. A ministry is called ''Behörde'' (office) and a state minister is a ''Senator'' in Hamburg. The legislature is the state parliament, called '' Hamburgische Bürgerschaft'', and the judicial branch is composed of the state supreme court and other courts. The seat of the government is Hamburg Rathaus. The President of the Hamburg Parliament is the highest official person of the Free and Hanseatic City of Hamburg.constitution of the Free and Hanseatic City of Hamburg, § 18 This is a traditional difference to the other German states. The president i ...
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Stratum Granulosum
The stratum granulosum (or granular layer) is a thin layer of cells in the epidermis lying above the stratum spinosum and below the stratum corneum (stratum lucidum on the soles and palms).James, William; Berger, Timothy; Elston, Dirk (2005) ''Andrews' Diseases of the Skin: Clinical Dermatology'' (10th ed.). Saunders. Page 2. . Keratinocytes migrating from the underlying stratum spinosum become known as granular cells in this layer. These cells contain keratohyalin granules, which are filled with histidine- and cysteine-rich proteins that appear to bind the keratin filaments together. Therefore, the main function of keratohyalin granules is to bind intermediate keratin filaments together.Marks, James G; Miller, Jeffery (2006). ''Lookingbill and Marks' Principles of Dermatology'' (4th ed.). Elsevier Inc. Page 7. . At the transition between this layer and the stratum corneum, cells secrete lamellar bodies (containing lipids and proteins) into the extracellular space. This results ...
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Resorcinol
Resorcinol (or resorcin) is an organic compound with the formula C6H4(OH)2. It is one of three isomeric benzenediols, the 1,3-isomer (or '' meta''-isomer). Resorcinol crystallizes from benzene as colorless needles that are readily soluble in water, alcohol, and ether, but insoluble in chloroform and carbon disulfide. Production Resorcinol is produced in several steps from benzene, starting with dialkylation with propylene to give 1,3-diisopropylbenzene. Oxidation and Hock rearrangement of this disubstituted arene gives acetone and resorcinol. Resorcinol is an expensive chemical, produced in only a very few locations around the world (to date only four commercial plants are known to be operative: in the United States, Germany,China and Japan), and as such it is the determining factor in the cost of PRF adhesives. Many additional routes exist for resorcinol. It was formerly produced by disulfonation of benzene followed by hydrolysis of the 1,3-disulfonate. This method ha ...
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