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Paul Brehm
Paul Brehm is a researcher at the Vollum Institute at Oregon Health and Science University. It was during a seminar by Brehm that Martin Chalfie became inspired to work on Green fluorescent protein for which Chalfie shared the Nobel Prize in Chemistry in 2008. Biography He graduated in zoology from the University of Wisconsin–Madison and earned his Ph.D. UCLA focusing on marine biology and bioluminescence under James Morin. Postgraduate training with Roger Eckert at UCLA and Yoshi Kidokoro at the Salk Institute focused on calcium channels and synaptic transmission. The next 10 years were spent as an associate professor in physiology at Tufts Medical School and summers at the Marine Biological Laboratory at Woods Hole Woods Hole is a census-designated place in the town of Falmouth in Barnstable County, Massachusetts, United States. It lies at the extreme southwest corner of Cape Cod, near Martha's Vineyard and the Elizabeth Islands. The population was 781 at .... In 1990 h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vollum Institute
The Vollum Institute is an independent research institute located in Marquam Hill Campus of the Oregon Health and Science University (OHSU) in southwest Portland, Oregon, USA. The institute is closely affiliated with the School of Medicine and many other the universities nearby. Establishment The institute was founded in 1987, and is a privately endowed organization named after Howard Vollum, a pioneer in the development of oscilloscopes and the co-founder of Tektronix. The research support for the faculty comes from the National Institutes of Health, federally sponsored programs, and also from the private funds of the Howard Hughes Medical Institute and the endowment created by Howard Vollum, which is controlled by the Oregon Health and Science University Foundation. The institute's building was designed by Robert Frasca of Zimmer-Gunsul-Frasca, and the 67,000 square foot structure was completed in 1987. In 1988, the institute received the Laboratory of the Year award from th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Salk Institute
The Salk Institute for Biological Studies is a scientific research institute located in the La Jolla community of San Diego, California, U.S. The independent, non-profit institute was founded in 1960 by Jonas Salk, the developer of the polio vaccine; among the founding consultants were Jacob Bronowski and Francis Crick. Construction of the research facilities began in spring of 1962. The Salk Institute consistently ranks among the top institutions in the US in terms of research output and quality in the life sciences. In 2004, the ''Times Higher Education Supplement'' ranked Salk as the world's top biomedicine research institute, and in 2009 it was ranked number one globally by '' ScienceWatch'' in the neuroscience and behavior areas. The Salk Institute employs 850 researchers in 60 research groups and focuses its research in three areas: molecular biology and genetics; neurosciences; and plant biology. Research topics include aging, cancer, diabetes, birth defects, Alzheimer's dis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Year Of Birth Missing (living People)
A year or annus is the orbital period of a planetary body, for example, the Earth, moving in its orbit around the Sun. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by change in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are generally recognized: spring, summer, autumn and winter. In tropical and subtropical regions, several geographical sectors do not present defined seasons; but in the seasonal tropics, the annual wet and dry seasons are recognized and tracked. A calendar year is an approximation of the number of days of the Earth's orbital period, as counted in a given calendar. The Gregorian calendar, or modern calendar, presents its calendar year to be either a common year of 365 days or a leap year of 366 days, as do the Julian calendars. For the Gregorian calendar, the average length of the calendar year (the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
OHSU
Oregon Health & Science University (OHSU) is a public research university focusing primarily on health sciences with a main campus, including two hospitals, in Portland, Oregon. The institution was founded in 1887 as the University of Oregon Medical Department and later became the University of Oregon Medical School. In 1974, the campus became an independent, self-governed institution called the University of Oregon Health Sciences Center, combining state dentistry, medicine, nursing, and public health programs into a single center. It was renamed Oregon Health Sciences University in 1981 and took its current name in 2001, as part of a merger with the Oregon Graduate Institute (OGI), in Hillsboro. The university has several partnership programs including a joint PharmD Pharmacy program with Oregon State University in Corvallis. The university's programs are highly ranked nationally, with the School of Medicine ranking in the top 5 for primary care and family medicine residency r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Woods Hole
Woods Hole is a census-designated place in the town of Falmouth in Barnstable County, Massachusetts, United States. It lies at the extreme southwest corner of Cape Cod, near Martha's Vineyard and the Elizabeth Islands. The population was 781 at the 2010 census. It is the site of several marine science institutions, including Woods Hole Oceanographic Institution, the Marine Biological Laboratory, the Woodwell Climate Research Center, NOAA's Northeast Fisheries Science Center (which started the Woods Hole scientific community in 1871), the Woods Hole Science Aquarium, a USGS coastal and marine geology center, and the home campus of the Sea Education Association. And the headquarter of the Climate Foundation. It is also the site of United States Coast Guard Sector Southeastern New England (formerly USCG Group Woods Hole), the Nobska Light lighthouse, and the terminus of the Steamship Authority ferry route between Cape Cod and the island of Martha's Vineyard. History Histor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tufts Medical School
The Tufts University School of Medicine is the medical school of Tufts University, a private research university in Massachusetts. It was established in 1893 and is located on the university's health sciences campus in downtown Boston. The ''Times Higher Education (THE)'' and the ''Academic Ranking of World Universities (ARWU)'' consistently rank Tufts among the world's best medical research institutions for clinical medicine. It has clinical affiliations with thousands of doctors and researchers in the United States and around the world, as well as at its affiliated hospitals in both Massachusetts (including Tufts Medical Center, St. Elizabeth's Medical Center, Lahey Hospital and Medical Center and Baystate Medical Center), and Maine (Maine Medical Center). According to Thomson Reuters' '' Science Watch'', Tufts University School of Medicine's research impact rates sixth among U.S medical schools for its overall medical research and within the top 5 for specialized research ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physiology
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical and physical functions in a living system. According to the classes of organisms, the field can be divided into medical physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. Central to physiological functioning are biophysical and biochemical processes, homeostatic control mechanisms, and communication between cells. ''Physiological state'' is the condition of normal function. In contrast, ''pathological state'' refers to abnormal conditions, including human diseases. The Nobel Prize in Physiology or Medicine is awarded by the Royal Swedish Academy of Sciences for exceptional scientific achievements in physiology related to the field of medicine. Foundations Cells Although there are differ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Calcium Channels
A calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel, although there are also ligand-gated calcium channels. Comparison tables The following tables explain gating, gene, location and function of different types of calcium channels, both voltage and ligand-gated. Voltage-gated Ligand-gated *the ''receptor-operated calcium channels'' (in vasoconstriction) **P2X receptors Page 479 Pharmacology L-type calcium channel blockers are used to treat hypertension. In most areas of the body, depolarization is mediated by sodium influx into a cell; changing the calcium permeability has little effect on action potentials. However, in many smooth muscle tissues, depolarization is mediated primarily by calcium influx into the cell. L-type calcium channel blockers selectively inhibit these action potentials in smooth muscle which leads to dilation of blood vessels; this in turn corrects hypertens ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yoshi Kidokoro
Yoshi is a fictional dinosaur who appears in video games published by Nintendo. Yoshi debuted in ''Super Mario World'' (1990) on the Super Nintendo Entertainment System as Mario and Luigi's sidekick. Yoshi is the title character of the List of Yoshi video games, ''Yoshi'' series and a supporting character in Mario (franchise), ''Mario'' spin-off games such as ''Mario Party'' and ''Mario Kart'', as well as many List of Mario sports games, ''Mario'' sports games. He also appears as a playable character in crossover fighting game ''Super Smash Bros.'' series. Yoshi is a member of the same-named species, which is distinguished for its wide range of colors. Yoshi was well-received, with some critics noting that he is one of the most recognizable characters and one of the best sidekicks in video games. Yoshi's image has also appeared on a range of products, including clothes and collectibles. Concept and creation Shigeru Miyamoto, the video game designer at Nintendo credited with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oregon Health And Science University
Oregon () is a state in the Pacific Northwest region of the Western United States. The Columbia River delineates much of Oregon's northern boundary with Washington, while the Snake River delineates much of its eastern boundary with Idaho. The 42° north parallel delineates the southern boundary with California and Nevada. Oregon has been home to many indigenous nations for thousands of years. The first European traders, explorers, and settlers began exploring what is now Oregon's Pacific coast in the early-mid 16th century. As early as 1564, the Spanish began sending vessels northeast from the Philippines, riding the Kuroshio Current in a sweeping circular route across the northern part of the Pacific. In 1592, Juan de Fuca undertook detailed mapping and studies of ocean currents in the Pacific Northwest, including the Oregon coast as well as the strait now bearing his name. Spanish ships – 250 in as many years – would typically not land before reaching Cape Mendocino ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Roger Eckert
Roger is a given name, usually masculine, and a surname. The given name is derived from the Old French personal names ' and '. These names are of Germanic origin, derived from the elements ', ''χrōþi'' ("fame", "renown", "honour") and ', ' ("spear", "lance") (Hrōþigēraz). The name was introduced into England by the Normans. In Normandy, the Frankish name had been reinforced by the Old Norse cognate '. The name introduced into England replaced the Old English cognate '. ''Roger'' became a very common given name during the Middle Ages. A variant form of the given name ''Roger'' that is closer to the name's origin is '' Rodger''. Slang and other uses Roger is also a short version of the term " Jolly Roger", which refers to a black flag with a white skull and crossbones, formerly used by sea pirates since as early as 1723. From up to , Roger was slang for the word " penis". In '' Under Milk Wood'', Dylan Thomas writes "jolly, rodgered" suggesting both the sexual do ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioluminescence
Bioluminescence is the production and emission of light by living organisms. It is a form of chemiluminescence. Bioluminescence occurs widely in marine vertebrates and invertebrates, as well as in some fungi, microorganisms including some bioluminescent bacteria, and terrestrial arthropods such as fireflies. In some animals, the light is bacteriogenic, produced by symbiotic bacteria such as those from the genus ''Vibrio''; in others, it is autogenic, produced by the animals themselves. In a general sense, the principal chemical reaction in bioluminescence involves a light-emitting molecule and an enzyme, generally called luciferin and luciferase, respectively. Because these are generic names, luciferins and luciferases are often distinguished by the species or group, e.g. firefly luciferin. In all characterized cases, the enzyme catalyzes the oxidation of the luciferin. In some species, the luciferase requires other cofactors, such as calcium or magnesium ions, and somet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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