Panos Ioannou
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Panos Ioannou
Panayiotis "Panos" Ioannou ( el, Παναγιώτης (Πάνος) Ιωάννου; 26 January 1951 – 18 April 2005) was an internationally known cell biologist and neuroscientist who pioneered in research on Thalassemia. He was born in Kalograia, in the Kyrenia District of Cyprus on 26 January 1951. He died on 18 April 2005 in Melbourne, Australia at the age of 54. In 1966 after the death of his younger brother from Hodgkin's disease he and his family moved to London, United Kingdom. Panayiotis Ioannou received both his B.Sc. and his Ph.D. in biochemistry from University College, London, with a focus on the molecular mechanisms of memory laydown. His fascination with the mechanism of DNA replication also led him to publish a model for this mechanism in Nature while still a student. Ioannou set up and ran for almost 15 years the Prenatal Diagnosis for Thalassaemia in Cyprus, followed by the setting up of the Department of Molecular Genetics in the Cyprus Institute of Neurolo ...
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Cell Biologist
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of organisms. Cell biology is the study of structural and functional units of cells. Cell biology encompasses both prokaryotic and eukaryotic cells and has many subtopics which may include the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition. The study of cells is performed using several microscopy techniques, cell culture, and cell fractionation. These have allowed for and are currently being used for discoveries and research pertaining to how cells function, ultimately giving insight into understanding larger organisms. Knowing the components of cells and how cells work is fundamental to all biological sciences while also being essential for research in biomedical fields such a ...
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DNA Replication
In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule. DNA replication occurs in all living organisms acting as the most essential part for biological inheritance. This is essential for cell division during growth and repair of damaged tissues, while it also ensures that each of the new cells receives its own copy of the DNA. The cell possesses the distinctive property of division, which makes replication of DNA essential. DNA is made up of a double helix of two complementary strands. The double helix describes the appearance of a double-stranded DNA which is thus composed of two linear strands that run opposite to each other and twist together to form. During replication, these strands are separated. Each strand of the original DNA molecule then serves as a template for the production of its counterpart, a process referred to as semiconservative replication. As a result of semi-conservative rep ...
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1951 Births
Events January * January 4 – Korean War: Third Battle of Seoul – Chinese and North Korean forces capture Seoul for the second time (having lost the Second Battle of Seoul in September 1950). * January 9 – The Government of the United Kingdom announces abandonment of the Tanganyika groundnut scheme for the cultivation of peanuts in the Tanganyika Territory, with the writing off of £36.5M debt. * January 15 – In a court in West Germany, Ilse Koch, The "Witch of Buchenwald", wife of the commandant of the Buchenwald concentration camp, is sentenced to life imprisonment. * January 20 – Winter of Terror: Avalanches in the Alps kill 240 and bury 45,000 for a time, in Switzerland, Austria and Italy. * January 21 – Mount Lamington in Papua New Guinea erupts catastrophically, killing nearly 3,000 people and causing great devastation in Oro Province. * January 25 – Dutch author Anne de Vries releases the first volume of his children's novel '' Journey Through ...
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The Cyprus Institute Of Neurology And Genetics
The Cyprus Institute of Neurology and Genetics is a non-profit institution that was established in 1990. It specialises in neurology, molecular biology and all aspects of human genetics. It also collaborates with the University of Cyprus on a Medical Genetics graduate programme. See also *Cyprus Neuroscience and Technology Institute *The Cyprus Institute The Cyprus Institute is a non-profit research and educational institution with a strong scientific and technological orientation, addressing issues of regional interest but of global significance, with an emphasis on cross-disciplinary research a ... External links * Organizations established in 1990 Medical and health organisations based in Cyprus Neuroscience research centers in Cyprus Research institutes in Cyprus 1990 establishments in Cyprus {{Cyprus-stub ...
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Genomic Library
A genomic library is a collection of the total genomic DNA from a single organism. The DNA is stored in a population of identical vectors, each containing a different insert of DNA. In order to construct a genomic library, the organism's DNA is extracted from cells and then digested with a restriction enzyme to cut the DNA into fragments of a specific size. The fragments are then inserted into the vector using DNA ligase. Next, the vector DNA can be taken up by a host organism - commonly a population of Escherichia coli or yeast - with each cell containing only one vector molecule. Using a host cell to carry the vector allows for easy amplification and retrieval of specific clones from the library for analysis. There are several kinds of vectors available with various insert capacities. Generally, libraries made from organisms with larger genomes require vectors featuring larger inserts, thereby fewer vector molecules are needed to make the library. Researchers can choose a vect ...
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Lawrence Livermore National Laboratory
Lawrence Livermore National Laboratory (LLNL) is a federal research facility in Livermore, California, United States. The lab was originally established as the University of California Radiation Laboratory, Livermore Branch in 1952 in response to the detonation of the first atomic bomb by the Soviet Union during the Cold War. It later became autonomous in 1971 and was designated a national laboratory in 1981. A federally funded research and development center, Lawrence Livermore Lab is primarily funded by the U.S. Department of Energy and it is managed privately and operated by Lawrence Livermore National Security, LLC (a partnership of the University of California), Bechtel, BWX Technologies, AECOM, and Battelle Memorial Institute in affiliation with the Texas A&M University System. In 2012, the laboratory had the synthetic chemical element livermorium (element 116) named after it. Overview LLNL is self-described as a "premier research and development institution for sci ...
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UNESCO
The United Nations Educational, Scientific and Cultural Organization is a specialized agency of the United Nations (UN) aimed at promoting world peace and security through international cooperation in education, arts, sciences and culture. It has 193 member states and 12 associate members, as well as partners in the non-governmental, intergovernmental and private sector. Headquartered at the World Heritage Centre in Paris, France, UNESCO has 53 regional field offices and 199 national commissions that facilitate its global mandate. UNESCO was founded in 1945 as the successor to the League of Nations's International Committee on Intellectual Cooperation.English summary). Its constitution establishes the agency's goals, governing structure, and operating framework. UNESCO's founding mission, which was shaped by the Second World War, is to advance peace, sustainable development and human rights by facilitating collaboration and dialogue among nations. It pursues this objective t ...
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The Cyprus Institute Of Neurology And Genetics
The Cyprus Institute of Neurology and Genetics is a non-profit institution that was established in 1990. It specialises in neurology, molecular biology and all aspects of human genetics. It also collaborates with the University of Cyprus on a Medical Genetics graduate programme. See also *Cyprus Neuroscience and Technology Institute *The Cyprus Institute The Cyprus Institute is a non-profit research and educational institution with a strong scientific and technological orientation, addressing issues of regional interest but of global significance, with an emphasis on cross-disciplinary research a ... External links * Organizations established in 1990 Medical and health organisations based in Cyprus Neuroscience research centers in Cyprus Research institutes in Cyprus 1990 establishments in Cyprus {{Cyprus-stub ...
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Molecular Genetics
Molecular genetics is a sub-field of biology that addresses how differences in the structures or expression of DNA molecules manifests as variation among organisms. Molecular genetics often applies an "investigative approach" to determine the structure and/or function of genes in an organism's genome using genetic screens.  The field of study is based on the merging of several sub-fields in biology: classical Mendelian inheritance, Cell biology, cellular biology, molecular biology, biochemistry, and biotechnology. Researchers search for mutations in a gene or induce mutations in a gene to link a gene sequence to a specific phenotype. Molecular genetics is a powerful methodology for linking mutations to genetic conditions that may aid the search for treatments/cures for various genetics diseases. History For molecular genetics to develop as a discipline, several scientific discoveries were necessary.  The discovery of DNA as a means to transfer the genetic code of life f ...
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Thalassaemia
Thalassemias are inherited blood disorders characterized by decreased hemoglobin production. Symptoms depend on the type and can vary from none to severe. Often there is mild to severe anemia (low red blood cells or hemoglobin). Anemia can result in feeling tired and pale skin. There may also be bone problems, an enlarged spleen, yellowish skin, and dark urine. Slow growth may occur in children. Thalassemias are genetic disorders inherited from a person's parents. There are two main types, alpha thalassemia and beta thalassemia. The severity of alpha and beta thalassemia depends on how many of the four genes for alpha globin or two genes for beta globin are missing. Diagnosis is typically by blood tests including a complete blood count, special hemoglobin tests, and genetic tests. Diagnosis may occur before birth through prenatal testing. Treatment depends on the type and severity. Treatment for those with more severe disease often includes regular blood transfusions, iron chel ...
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Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 ''Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in exp ...
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University College, London
, mottoeng = Let all come who by merit deserve the most reward , established = , type = Public research university , endowment = £143 million (2020) , budget = £1.544 billion (2019/20) , chancellor = Anne, Princess Royal(as Chancellor of the University of London) , provost = Michael Spence , head_label = Chair of the council , head = Victor L. L. Chu , free_label = Visitor , free = Sir Geoffrey Vos , academic_staff = 9,100 (2020/21) , administrative_staff = 5,855 (2020/21) , students = () , undergrad = () , postgrad = () , coordinates = , campus = Urban , city = London, England , affiliations = , colours = Purple and blue celeste , nickname ...
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