Pyrotherapy
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Pyrotherapy
Pyrotherapy (artificial fever) is a method of treatment by raising the body temperature or sustaining an elevated body temperature using a fever. In general, the body temperature was maintained at 41 °C (105 °F). Many diseases were treated by this method in the first half of the 20th century. In general, it was done by exposing the patient to hot baths, warm air, or (electric) blankets. The technique reached its peak of sophistication in the early 20th century with malariotherapy, in which '' Plasmodium vivax'', a causative agent of malaria, was allowed to infect already ill patients in order to produce intense fever for therapeutic ends. The sophistication of this approach lay in using effective anti-malarial drugs to control the ''P. vivax'' infection, while maintaining the fever it causes to the detriment of other, ongoing, and then-incurable infections present in the patient, such as late-stage syphilis. This type of pyrotherapy was most famously used by psychiatri ...
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Julius Wagner-Jauregg
Julius Wagner-Jauregg (; 7 March 1857 – 27 September 1940) was an Austrian physician, who won the Nobel Prize in Physiology or Medicine in 1927, and is the first psychiatrist to have done so. His Nobel award was "for his discovery of the therapeutic value of malaria inoculation in the treatment of dementia paralytica". Early life Julius Wagner-Jauregg was born Julius Wagner on 7 March 1857 in Wels, Upper Austria, the son of Adolph Johann Wagner and Ludovika Jauernigg Ranzoni."Physiology or medicine, 1922-1941"
Jan Lindsten. World Scientific, 1999. p. 170. , .
His family name was changed to "Wagner von Jauregg" when his father was given the title of "
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Sulfozinum
Sulfozinum (sulfozin) is a pharmaceutical drug that causes a pyrogenic reaction (body temperature elevation) and severe pain. Sulfozinum is a 0.37 - 2% sterilized solution of purified elemental sulfur in peach oil or olive oil for intramuscular injections. The preparation is unstable, so it was prepared only in local hospital pharmacies. In the Soviet Union, it was used in the pyrogenic treatment of syphilitic encephalitis (mostly in the pre-antibiotics era), various psychiatric conditions, and alcoholism. Sulfozin was not used in American psychiatry. The American delegation during its visit to the USSR in 1989 confirmed charges of the use of sulfozine injections. Psychiatrists in the USSR employed sulfozine treatment allegedly to increase treatment response to neuroleptic administration but were unable to present any research evidence of its efficiency for this purpose. The muscle necrosis, fever, immobility, and severe pain caused by sulfozine, as well as the pattern of its us ...
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General Paresis Of The Insane
General paresis, also known as general paralysis of the insane (GPI), paralytic dementia, or syphilitic paresis is a severe neuropsychiatric disorder, classified as an organic mental disorder and is caused by late-stage syphilis and the chronic meningoencephalitis and cerebral atrophy that are associated with this late stage of the disease when left untreated. GPI differs from mere paresis, as mere paresis can result from multiple other causes and usually does not affect cognitive function. Degenerative changes caused by GPI are associated primarily with the frontal and temporal lobar cortex. The disease affects approximately 7% of individuals infected with syphilis, and is far more common in third world countries where fewer options for timely treatment are available. It is more common among men. GPI was originally considered to be a type of madness due to a dissolute character, when first identified in the early 19th century. The condition's connection with syphilis was d ...
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Core Temperature
Normal human body-temperature (normothermia, euthermia) is the typical temperature range found in humans. The normal human body temperature range is typically stated as . Human body temperature varies. It depends on sex, age, time of day, exertion level, health status (such as illness and menstruation), what part of the body the measurement is taken at, state of consciousness (waking, sleeping, sedated), and emotions. Body temperature is kept in the normal range by thermoregulation, in which adjustment of temperature is triggered by the central nervous system. Methods of measurement Taking a person's temperature is an initial part of a full clinical examination. There are various types of medical thermometers, as well as sites used for measurement, including: * In the rectum (rectal temperature) * In the mouth (oral temperature) * Under the arm (axillary temperature) * In the ear (tympanic temperature) * On the skin of the forehead over the temporal artery * Using heat fl ...
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Penicillin
Penicillins (P, PCN or PEN) are a group of β-lactam antibiotics originally obtained from '' Penicillium'' moulds, principally '' P. chrysogenum'' and '' P. rubens''. Most penicillins in clinical use are synthesised by P. chrysogenum using deep tank fermentation and then purified. A number of natural penicillins have been discovered, but only two purified compounds are in clinical use: penicillin G (intramuscular or intravenous use) and penicillin V (given by mouth). Penicillins were among the first medications to be effective against many bacterial infections caused by staphylococci and streptococci. They are still widely used today for different bacterial infections, though many types of bacteria have developed resistance following extensive use. 10% of the population claims penicillin allergies but because the frequency of positive skin test results decreases by 10% with each year of avoidance, 90% of these patients can tolerate penicillin. Additionally, those wi ...
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Heroic Measure
In medicine, heroic treatment or course of therapy is one which possesses a high risk of causing further damage to a patient's health, but is undertaken as a last resort with the understanding that any lesser treatment will surely result in failure. Heroic measures are often taken in cases of grave injury or illness, as a last-ditch attempt to save life, limb, or eyesight. Examples include emergency trauma surgery conducted outside the operating room (such as "on-scene" surgical amputation, cricothyroidotomy, or thoracotomy), or administration of medication (such as certain antibiotics and chemotherapy drugs) at dosage levels high enough to potentially cause serious or fatal side effects. Cardiopulmonary resuscitation is a particularly well-known heroic measure; vigorous chest compressions often result in fracturing one or more of the patient's ribs, but since the alternative is certain death, the technique is accepted as necessary. Patients with advanced AIDS and concomitant ...
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Schizophrenia
Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social withdrawal, decreased emotional expression, and apathy. Symptoms typically develop gradually, begin during young adulthood, and in many cases never become resolved. There is no objective diagnostic test; diagnosis is based on observed behavior, a history that includes the person's reported experiences, and reports of others familiar with the person. To be diagnosed with schizophrenia, symptoms and functional impairment need to be present for six months ( DSM-5) or one month (ICD-11). Many people with schizophrenia have other mental disorders, especially substance use disorders, depressive disorders, anxiety disorders, and obsessive–compulsive disorder. About 0.3% to 0.7% of people are diagnosed with schizophrenia during their lifetim ...
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Soviet Psychiatry
This list of Russian physicians and psychologists includes the famous physicians and psychologists, medical scientists and medical doctors from the Russian Federation, the Soviet Union, the Russian Empire and other predecessor states of Russia. Physicians of all specialties may be listed here. Alphabetical list __NOTOC__ A *Nikolai Amosov, prominent cardiovascular surgery developer, best-selling author B *Aleksandr Bakulev, prominent cardiovascular surgery developer *Vladimir Bekhterev, neuropathologist, founder of objective psychology, noted the role of the hippocampus in memory, major contributor to reflexology, studied the Bekhterev’s Disease *Vladimir Betz, discovered Betz cells of primary motor cortex *Peter Borovsky, described the causative agent of Oriental sore *Sergey Botkin, major therapist and court physician *Nikolay Burdenko, major developer of neurosurgery *Konstantin Buteyko, developed the Buteyko method for the treatment of asthma and other breathing disorde ...
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Psychiatry
Psychiatry is the specialty (medicine), medical specialty devoted to the diagnosis, prevention, and treatment of mental disorders. These include various maladaptations related to mood, behaviour, cognition, and perceptions. See glossary of psychiatry. Initial psychiatric assessment of a person typically begins with a Medical history, case history and mental status examination. Physical examinations and Psychological testing, psychological tests may be conducted. On occasion, neuroimaging or other Neurophysiology, neurophysiological techniques are used. Mental disorders are often diagnosed in accordance with clinical concepts listed in diagnostic manuals such as the ''International Classification of Diseases'' (ICD), edited and used by the World Health Organization (WHO) and the widely used ''Diagnostic and Statistical Manual of Mental Disorders'' (DSM), published by the American Psychiatric Association (APA). The fifth edition of the DSM (DSM-5) was published in May 2013 which re ...
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Pediatrics (journal)
''Pediatrics'' is a peer-reviewed medical journal published by the American Academy of Pediatrics. In the inaugural January 1948 issue, the journal's first editor-in-chief, Hugh McCulloch, articulated the journal's vision: "The content of the journal is... intended to encompass the needs of the whole child in his physiologic, mental, emotional, and social structure. The single word, Pediatrics, has been chosen to indicate this catholic intent." ''Pediatrics'' has been continuously published by the American Academy of Pediatrics since January 1948. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 7.124, ranking it fourth out of 119 journals in the category "Pediatrics". Editors The following persons have been editor-in-chief of ''Pediatrics'': *1948–1954 Hugh McCulloch *1954–1961 Charles D. May *1962–1974 Clement A. Smith Clement Andrew Smith (1901 – December 31, 1988) was an American pediatrician and the editor-in-chief of the journal ' ...
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Treponema Pallidum
''Treponema pallidum'', formerly known as ''Spirochaeta pallida'', is a spirochaete bacterium with various subspecies that cause the diseases syphilis, bejel (also known as endemic syphilis), and yaws. It is transmitted only among humans. It is a helically coiled microorganism usually 6–15 μm long and 0.1–0.2 μm wide. ''T. pallidum'''s lack of either a tricarboxylic acid cycle or oxidative phosphorylation results in minimal metabolic activity. The treponemes have a cytoplasmic and an outer membrane. Using light microscopy, treponemes are visible only by using dark field illumination. ''Treponema pallidum'' consists of three subspecies, ''T. p. pallidum, T. p. endemicum,'' and ''T. p. pertenue,'' each of which has a distinct associated disease. Subspecies Three subspecies of ''T. pallidum'' are known: * ''Treponema pallidum pallidum'', which causes syphilis * ''T. p. endemicum'', which causes bejel or endemic syphilis * ''T. p. pertenue'', which causes yaws T ...
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