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Puberty Blockers
Puberty blockers, also called puberty inhibitors or hormone blockers, are medicines used to postpone puberty in children. The most commonly used puberty blockers are gonadotropin-releasing hormone (GnRH) agonists, which suppress the production of sex hormones, including testosterone and estrogen. In addition to their use in treating precocious puberty (and sometimes idiopathic short stature) in children, puberty blockers are also used for transgender children to delay the development of unwanted sex characteristics, so as to allow transgender youth more time to explore their gender identity. The use of puberty blockers in transgender youth is supported by twelve major American medical associations, four Australian medical associations, the British Medical Association, and the World Professional Association for Transgender Health (WPATH). In Europe, some medical groups and countries have discouraged or limited the use of puberty blockers, including Sweden's National Board of He ...
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Puberty
Puberty is the process of physical changes through which a child's body matures into an adult body capable of sexual reproduction. It is initiated by hormonal signals from the brain to the gonads: the ovaries in a girl, the testes in a boy. In response to the signals, the gonads produce hormones that stimulate libido and the growth, function, and transformation of the brain, bones, muscle, blood, skin, hair, breasts, and sex organs. Physical growth—height and weight—accelerates in the first half of puberty and is completed when an adult body has been developed. Before puberty, the external sex organs, known as primary sexual characteristics, are sex characteristics that distinguish boys and girls. Puberty leads to sexual dimorphism through the development of the secondary sex characteristics, which further distinguish the sexes. On average, girls begin puberty at ages 10–11 and complete puberty at ages 15–17; boys generally begin puberty at ages 11–12 and complete ...
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National Board Of Health And Welfare (Sweden)
The Swedish National Board of Health and Welfare ( sv, Socialstyrelsen) is a Swedish government agency. The agency was the result of a merger between the National Swedish Board of Health and the Swedish Royal Board of Social Affairs in 1968. , it is headed by director-general Olivia Wigzell. The Board is the central national authority for social services, public health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ..., infectious diseases prevention and health services. The Board establishes norms by issuing provisions and general advice. It evaluates legislation and activities conducted by municipalities, county councils and local authorities. It also issues certificates of registration to 17 professional groups. Another responsibility are the official national statist ...
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Hormone
A hormone (from the Greek participle , "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs by complex biological processes to regulate physiology and behavior. Hormones are required for the correct development of animals, plants and fungi. Due to the broad definition of a hormone (as a signaling molecule that exerts its effects far from its site of production), numerous kinds of molecules can be classified as hormones. Among the substances that can be considered hormones, are eicosanoids (e.g. prostaglandins and thromboxanes), steroids (e.g. oestrogen and brassinosteroid), amino acid derivatives (e.g. epinephrine and auxin), protein or peptides (e.g. insulin and CLE peptides), and gases (e.g. ethylene and nitric oxide). Hormones are used to communicate between organs and tissues. In vertebrates, hormones are responsible for regulating a variety of physiological processes and behavioral activities such as diges ...
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Sexual Organ
A sex organ (or reproductive organ) is any part of an animal or plant that is involved in sexual reproduction. The reproductive organs together constitute the reproductive system. In animals, the testis in the male, and the ovary in the female, are called the ''primary sex organs''. All others are called ''secondary sex organs'', divided between the external sex organs—the genitals or external genitalia, visible at birth in both sexes—and the internal sex organs. Mosses, ferns, and some similar plants have gametangia for reproductive organs, which are part of the gametophyte. The flowers of flowering plants produce pollen and egg cells, but the sex organs themselves are inside the gametophytes within the pollen and the ovule. Coniferous plants likewise produce their sexually reproductive structures within the gametophytes contained within the cones and pollen. The cones and pollen are not themselves sexual organs. Terminology The ''primary sex organs'' are the gonads, a p ...
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Annual Review Of Medicine
The ''Annual Review of Medicine'' is a peer-reviewed medical journal that publishes review articles about all aspects of medicine. It was established in 1950. Its longest-serving editors have been William P. Creger (1974–1993) and C. Thomas Caskey (2001–2019). The current editor is Mary E. Klotman. As of 2022, ''Journal Citation Reports'' gives the journal a 2021 impact factor of 16.048, ranking it seventh of 139 titles in the category "Medicine, Research & Experimental". History The first volume of the journal was published in 1950 by the nonprofit publishing company Annual Reviews. It noted that the more "active" areas of medicine would be covered in each volume, while other subdisciplines would be covered every two or three years. Its first editor was Windsor C. Cutting. In 1996, it was one of the first Annual Reviews journals to be published electronically. Editors of volumes Dates indicate publication years in which someone was credited as a lead editor or co-editor ...
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Secondary Sex Characteristics
Secondary sex characteristics are features that appear during puberty in humans, and at sexual maturity in other animals. These characteristics are particularly evident in the sexually dimorphic phenotypic traits that distinguish the sexes of a species, but unlike the sex organs (primary sex characteristics), are not directly part of the reproductive system. Secondary sex characteristics are believed to be the product of sexual selection for traits which display fitness, giving an organism an advantage over its rivals in courtship and in aggressive interactions. Secondary sex characteristics include, for example, the manes of male lions, the bright facial and rump coloration of male mandrills, and horns in many goats and antelopes. These characteristics are believed to be produced by a positive feedback loop known as the Fisherian runaway produced by the secondary characteristic in one sex and the desire for that characteristic in the other sex. Male birds and fish of many species ...
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Polycystic Ovary Syndrome
Polycystic ovary syndrome, or PCOS, is the most common endocrine disorder in women of reproductive age. The syndrome is named after the characteristic cysts which may form on the ovaries, though it is important to note that this is a sign and not the underlying cause of the disorder. Women with PCOS may experience irregular menstrual periods, heavy periods, excess hair, acne, pelvic pain, difficulty getting pregnant, and patches of thick, darker, velvety skin. The primary characteristics of this syndrome include: hyperandrogenism, anovulation, insulin resistance, and neuroendocrine disruption. A review of the international evidence found that the prevalence of PCOS could be as high as 26% among some populations, though ranges between 4% and 18% are reported for general populations. Despite its high prevalence, the exact cause of PCOS remains uncertain and there is no known cure. Definition Two definitions are commonly used: * NIH : In 1990 a consensus workshop sponsore ...
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Prostate Cancer
Prostate cancer is cancer of the prostate. Prostate cancer is the second most common cancerous tumor worldwide and is the fifth leading cause of cancer-related mortality among men. The prostate is a gland in the male reproductive system that surrounds the urethra just below the bladder. It is located in the hypogastric region of the abdomen. To give an idea of where it is located, the bladder is superior to the prostate gland as shown in the image The rectum is posterior in perspective to the prostate gland and the ischial tuberosity of the pelvic bone is inferior. Only those who have male reproductive organs are able to get prostate cancer. Most prostate cancers are slow growing. Cancerous cells may spread to other areas of the body, particularly the bones and lymph nodes. It may initially cause no symptoms. In later stages, symptoms include pain or difficulty urinating, blood in the urine, or pain in the pelvis or back. Benign prostatic hyperplasia may produce similar symptoms ...
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Breast Cancer
Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. In those with distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or yellow skin. Risk factors for developing breast cancer include obesity, a lack of physical exercise, alcoholism, hormone replacement therapy during menopause, ionizing radiation, an early age at first menstruation, having children late in life or not at all, older age, having a prior history of breast cancer, and a family history of breast cancer. About 5–10% of cases are the result of a genetic predisposition inherited from a person's parents, including BRCA1 and BRCA2 among others. Breast cancer most commonly develops in cells from the lining of milk ducts and the lobules that supply these ...
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Endometriosis
Endometriosis is a disease of the female reproductive system in which cells similar to those in the endometrium, the layer of tissue that normally covers the inside of the uterus, grow outside the uterus. Most often this is on the ovaries, fallopian tubes, and tissue around the uterus and ovaries; in rare cases it may also occur in other parts of the body. Some symptoms include pelvic pain, heavy periods, pain with bowel movements, and infertility. Nearly half of those affected have chronic pelvic pain, while in 70% pain occurs during menstruation. Pain during sexual intercourse is also common. Infertility occurs in up to half of affected individuals. About 25% of individuals have no symptoms and 85% of those seen with infertility in a tertiary center have no pain. Endometriosis can have both social and psychological effects. The cause is not entirely clear. Risk factors include having a family history of the condition. The areas of endometriosis bleed each month (menstrua ...
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Endocrine Practice
''Endocrine Practice'' is a bimonthly peer-reviewed medical journal covering endocrinology. It was established in 1995, and is the official journal of the American Association of Clinical Endocrinologists (AACE) and the American College of Endocrinology (ACE). It is published by AACECOR, Inc., a subsidiary of the AACE and ACE, and the editor-in-chief is Derek LeRoith (Icahn School of Medicine at Mount Sinai). According to the ''Journal Citation Reports'', the journal has a 2017 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 3.805. References External links *{{Official website, http://journals.aace.com/loi/endp Endocrinology journals Academic journals established in 1995 Bimonthly journals Academic journals published by learned and professional societies ...
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Oregon Health & Science University
Oregon Health & Science University (OHSU) is a public research university focusing primarily on health sciences with a main campus, including two hospitals, in Portland, Oregon. The institution was founded in 1887 as the University of Oregon Medical Department and later became the University of Oregon Medical School. In 1974, the campus became an independent, self-governed institution called the University of Oregon Health Sciences Center, combining state dentistry, medicine, nursing, and public health programs into a single center. It was renamed Oregon Health Sciences University in 1981 and took its current name in 2001, as part of a merger with the Oregon Graduate Institute (OGI), in Hillsboro. The university has several partnership programs including a joint PharmD Pharmacy program with Oregon State University in Corvallis. The university's programs are highly ranked nationally, with the School of Medicine ranking in the top 5 for primary care and family medicine residency r ...
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