Psychotria Colorata
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Psychotria Colorata
''Psychotria colorata'' is a species of plant in the family Rubiaceae. It has been documented in an ethnobotanical context among the Ka'apor people of Maranhão, Brazil by Dr. William Balée, the Tulane University anthropologist and historical ecologist: "Fishhooks (pinar) and line (pina-ham) are obtained through trade. The bait is usually worms, but two species of plants serve an intermediate role. Fruits of the rubiaceous forest herb ''Psychotria colorata'' and seeds of ''Ricinus communis'', a treelet of dooryard gardens, are used for baiting hooks and catching small fish: characins called ''pirapisi''. Fishermen cut chunks of the characins as bait for hooking larger, more desirable fish" (Balée 1994: 61). "It is said that a boy should rub leaves of tapesi'i (Cephalia sp. 1) or leaves of ''Psychotria colorata'' (tapi'ika'a), both of which are in the madder family, between his hands so that upon maturity he will be able to fashion well the manioc press (tapesi), an exclusive ...
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Rubiaceae
The Rubiaceae are a family of flowering plants, commonly known as the coffee, madder, or bedstraw family. It consists of terrestrial trees, shrubs, lianas, or herbs that are recognizable by simple, opposite leaves with interpetiolar stipules and sympetalous actinomorphic flowers. The family contains about 13,500 species in about 620 genera, which makes it the fourth-largest angiosperm family. Rubiaceae has a cosmopolitan distribution; however, the largest species diversity is concentrated in the tropics and subtropics. Economically important genera include ''Coffea'', the source of coffee, '' Cinchona'', the source of the antimalarial alkaloid quinine, ornamental cultivars (''e.g.'', '' Gardenia'', ''Ixora'', ''Pentas''), and historically some dye plants (''e.g.'', ''Rubia''). Description The Rubiaceae are morphologically easily recognizable as a coherent group by a combination of characters: opposite or whorled leaves that are simple and entire, interpetiolar stipules, tubu ...
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Psychotria Colorata In Cultivation
''Psychotria'' is a genus of flowering plants in the family Rubiaceae. It contains 1,582 species and is therefore one of the largest genera of flowering plants. The genus has a pantropical distribution and members of the genus are small understorey trees in tropical forests. Some species are endangered or facing extinction due to deforestation, especially species of central Africa and the Pacific. Many species, including ''Psychotria viridis'', produce the psychedelic chemical dimethyltryptamine (DMT). Selected species * '' Psychotria abdita'' * ''Psychotria acutiflora'' * '' Psychotria adamsonii'' * '' Psychotria alsophila'' * '' Psychotria angustata'' * '' Psychotria atricaulis'' * ''Psychotria beddomei'' * ''Psychotria bimbiensis'' * ''Psychotria bryonicola'' * '' Psychotria camerunensis'' * '' Psychotria capensis'' * '' Psychotria carronis'' * ''Psychotria carthagenensis'' * ''Psychotria cathetoneura'' * '' Psychotria cernua' * '' Psychotria chalconeura'' * '' Psychotria ch ...
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Psychotria
''Psychotria'' is a genus of flowering plants in the family Rubiaceae. It contains 1,582 species and is therefore one of the largest genera of flowering plants. The genus has a pantropical distribution and members of the genus are small understorey trees in tropical forests. Some species are endangered or facing extinction due to deforestation, especially species of central Africa and the Pacific. Many species, including ''Psychotria viridis'', produce the psychedelic chemical dimethyltryptamine (DMT). Selected species * '' Psychotria abdita'' * '' Psychotria acutiflora'' * '' Psychotria adamsonii'' * '' Psychotria alsophila'' * '' Psychotria angustata'' * '' Psychotria atricaulis'' * ''Psychotria beddomei'' * '' Psychotria bimbiensis'' * '' Psychotria bryonicola'' * '' Psychotria camerunensis'' * '' Psychotria capensis'' * '' Psychotria carronis'' * '' Psychotria carthagenensis'' * '' Psychotria cathetoneura'' * '' Psychotria cernua' * '' Psychotria chalconeura'' * '' Psychot ...
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Psychotridine
Psychotridine is an alkaloid found in some species of the genus ''Psychotria'', namely '' Psychotria colorata'', but also '' Psychotria forsteriana'', '' Psychotria lyciiflora'', '' Psychotria oleoides'', and '' Psychotria beccarioides''. Psychotridine has analgesic effects and dose-dependently inhibits dizocilpine binding to cortical membranes ''in vitro'', suggesting that it acts as a non-competitive NMDA receptor antagonist NMDA receptor antagonists are a class of drugs that work to antagonize, or inhibit the action of, the ''N''-Methyl-D-aspartate receptor ( NMDAR). They are commonly used as anesthetics for animals and humans; the state of anesthesia they induce .... See also * Hodgkinsine References Alkaloids NMDA receptor antagonists Pyrroloindoles {{analgesic-stub ...
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NMDA Antagonist
NMDA receptor antagonists are a class of drugs that work to antagonize, or inhibit the action of, the ''N''-Methyl-D-aspartate receptor (NMDAR). They are commonly used as anesthetics for animals and humans; the state of anesthesia they induce is referred to as dissociative anesthesia. Several synthetic opioids function additionally as NMDAR-antagonists, such as pethidine, levorphanol, methadone, dextropropoxyphene, tramadol and ketobemidone. Some NMDA receptor antagonists, such as ketamine, dextromethorphan (DXM), phencyclidine (PCP), methoxetamine (MXE), and nitrous oxide (N2O), are sometimes used as recreational drugs, for their dissociative, hallucinogenic, and euphoriant properties. When used recreationally, they are classified as dissociative drugs. Uses and effects NMDA receptor antagonists induce a state called dissociative anesthesia, marked by catalepsy, amnesia, and analgesia. Ketamine is a favored anesthetic for emergency patients with unknown medical history and i ...
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Hodgkinsine
Hodgkinsine is an alkaloid found in plants of the genus ''Psychotria'', particularly '' Psychotria colorata'', although it is also found in ''Psychotria lyciiflora'' and probably other species in this family, Hodgkinsine has antiviral, antibacterial and antifungal effects, but has mainly been researched for the analgesic effects that it produces, and is thought to be one of the components responsible for the analgesic effects seen when ''Psychotria colorata'' is used in traditional medical practice in humans. It has been found to act as both a mu opioid agonist and an NMDA antagonist, both of which are mechanisms of action shared with commonly used painkillers (morphine and ketamine respectively, and which occur concurrently in the clinical analgesics tramadol and levorphanol). Hodgkinsine is a trimer composed of three pyrrolidinoindoline subunits, with the monomer closely resembling another alkaloid eseroline which has similar bioactivity. Due to its complex structure and mu ...
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Alkaloid
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids
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Alkaloids are produced by a large variety of organisms including , , Medicinal plant, plants, an ...
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Naloxone
Naloxone, sold under the brand names Narcan (4 mg) and Kloxxado (8 mg) among others, is a medication used to reverse or reduce the effects of opioids. It is commonly used to counter decreased breathing in opioid overdose. Effects begin within two minutes when given intravenously, and within five minutes when injected into a muscle. The medicine can also be administered by spraying it into a person's nose. Naloxone commonly blocks the effects of opioids for 30 to 90 minutes. Multiple doses may be required, as the duration of action of some opioids is greater than that of naloxone. Administration to opioid-dependent individuals may cause symptoms of opioid withdrawal, including restlessness, agitation, nausea, vomiting, a fast heart rate, and sweating. To prevent this, small doses every few minutes can be given until the desired effect is reached. In those with previous heart disease or taking medications that negatively affect the heart, further heart problems have occurred. ...
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Analgesic
An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It is typically used to induce cooperation with a medical procedure. Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and anesthetic effects. Analgesic choice is also determined by the type of pain: For neuropathic pain, traditional analgesics are less effective, and there is often benefit from classes of drugs that are not normally considered analgesics, such as tricyclic antidepressants and anticonvulsants. Various analgesics, such as many NSAIDs, are available over the counter in most countries, whereas various others are prescription drugs owing ...
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Rubia
''Rubia'' is the type genus of the Rubiaceae family of flowering plants, which also contains coffee. It contains around 80 species of perennial scrambling or climbing herbs and subshrubs native to the Old World. The genus and its best-known species are commonly known as madder, e.g. '' Rubia tinctorum'' (common madder), ''Rubia peregrina'' (wild madder), and ''Rubia cordifolia'' (Indian madder). Uses ''Rubia'' was an economically important source of a red pigment in many regions of Asia, Europe and Africa. The genus name ''Rubia'' derives from the Latin ' meaning "red". The plant's roots contain an anthracene compound called alizarin that gives its red colour to a textile dye known as Rose madder. It was also used as a colourant, especially for paint, that is referred to as Madder lake. The synthesis of alizarin greatly reduced demand for the natural compound. In Georgia, Rubia is used for dying Easter eggs in red. History Several species, such as '' Rubia tinctorum'' in Eu ...
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Ka'apor
The Ka'apor are an indigenous people of Brazil. They live on a protected reserve in the state of Maranhão. They were the subject of a book by anthropologist Dr. William Balée in an exhaustive study of their ethnobotany lifeways and the historical ecology of the area they currently inhabit. They live in a heavily deforested area of Pre-Amazonian forest, but have managed to protect the forest within their designated reserve. There is a high degree of congenital deafness among the Ka'apor, and consequently most of the hearing community knows sign language. (See Ka'apor Sign Language Ka'apor Sign Language (also known as Urubu Sign Language or Urubu–Ka'apor Sign Language, although these are pejorative) was a village sign language used by the small community of Ka'apor people in the Brazilian state of Maranhão. Linguist Jim ....) Their forest reserve is under attack from illegal loggers, and in September 2014 the tribe took matters into their own hands when they attacked a ...
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