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Proximal Origin
The Proximal Origin is a reference to a scientific correspondence titled "The proximal origin of SARS-CoV-2" and the events of scientific and political controversies arising from it. The letter, published in the journal '' Nature Medicine'' on 17 March 2020, was written by a group of virologists including Kristian G. Andersen, Andrew Rambaut, W. Ian Lipkin, Edward C. Holmes and Robert F. Garry. The authors examined possibilities of an accidental leak of a natural or manipulated virus from a laboratory, and concluded that genomic analyses indicated that "SARS-CoV-2 is not a laboratory construct or a purposefully manipulated virus." The letter was highly influential in establishing the natural origin of COVID-19 in the early stages of the pandemic and generated controversy over the arguments it made against any lab-based origin scenario, and the link later drawn between its authors and public health officials alleged to have funded gain-of-function research at the Wuhan Institut ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The virus previously had a provisional name, 2019 novel coronavirus (2019-nCoV), and has also been called the human coronavirus 2019 (HCoV-19 or hCoV-19). First identified in the city of Wuhan, Hubei, China, the World Health Organization declared the outbreak a public health emergency of international concern on January 30, 2020, and a pandemic on March 11, 2020. SARS‑CoV‑2 is a positive-sense single-stranded RNA virus that is contagious in humans. SARS‑CoV‑2 is a virus of the species ''severe acute respiratory syndrome–related coronavirus'' (SARSr-CoV), related to the SARS-CoV-1 virus that caused the 2002–2004 SARS outbreak. Despite its close relation to SARS-CoV-1, its closest known relatives, with which it forms a sister group, are the derived SARS ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthony Fauci
Anthony Stephen Fauci (; born December 24, 1940) is an American physician-scientist and immunologist serving as the director of the National Institute of Allergy and Infectious Diseases (NIAID) and the chief medical advisor to the president. As a physician with the National Institutes of Health (NIH), Fauci has served the American public health sector in various capacities for more than fifty years and has acted as an advisor to every U.S. president since Ronald Reagan. He has been director of the NIAID since 1984 and has made contributions to HIV/AIDS research and other immunodeficiency diseases, both as a research scientist and as the head of the NIAID. From 1983 to 2002, Fauci was one of the world's most frequently cited scientists across all scientific journals. In 2008, President George W. Bush awarded him the Presidential Medal of Freedom, the highest civilian award in the United States, for his work on the AIDS relief program PEPFAR. During the COVID-19 pandemic, h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Natural Selection
Natural selection is the differential survival and reproduction of individuals due to differences in phenotype. It is a key mechanism of evolution, the change in the heritable traits characteristic of a population over generations. Charles Darwin popularised the term "natural selection", contrasting it with selective breeding, artificial selection, which in his view is intentional, whereas natural selection is not. Genetic diversity, Variation exists within all populations of organisms. This occurs partly because random mutations arise in the genome of an individual organism, and their offspring can inherit such mutations. Throughout the lives of the individuals, their genomes interact with their environments to cause variations in traits. The environment of a genome includes the molecular biology in the Cell (biology), cell, other cells, other individuals, populations, species, as well as the abiotic environment. Because individuals with certain variants of the trait tend ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biological Evolution
Evolution is change in the heritable characteristics of biological populations over successive generations. These characteristics are the expressions of genes, which are passed on from parent to offspring during reproduction. Variation tends to exist within any given population as a result of genetic mutation and recombination. Evolution occurs when evolutionary processes such as natural selection (including sexual selection) and genetic drift act on this variation, resulting in certain characteristics becoming more common or more rare within a population. The evolutionary pressures that determine whether a characteristic is common or rare within a population constantly change, resulting in a change in heritable characteristics arising over successive generations. It is this process of evolution that has given rise to biodiversity at every level of biological organisation, including the levels of species, individual organisms, and molecules. The theory of evolution by n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tulane University
Tulane University, officially the Tulane University of Louisiana, is a private university, private research university in New Orleans, Louisiana. Founded as the Medical College of Louisiana in 1834 by seven young medical doctors, it turned into a comprehensive public university as the University of Louisiana by the state legislature in 1847. The institution became private under the endowments of Paul Tulane and Josephine Louise Newcomb in 1884 and 1887. Tulane is the 9th oldest private university in the Association of American Universities. The Tulane University Law School and Tulane University Medical School are, respectively, the 12th oldest law school and 15th oldest medical school in the United States. Tulane has been a member of the Association of American Universities since 1958 and is classified among "R1: Doctoral Universities – Very high research activity". Tulane has an overall acceptance rate of 8.4%. Alumni include twelve List of governors of Louisiana, governors o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sydney Medical School
The University of Sydney School of Medicine, also known as Sydney Medical School (SMS) is the graduate medical school of the University of Sydney. Established in 1856, it is the first medical school in Australia. In 2018, Sydney Medical School joined the newly formed Faculty of Medicine and Health at the University of Sydney. SMS is ranked 19th in the world and second in Australia in the 2021 QS Subject Rankings for medicine. The School has a large and diverse faculty to support its missions in education, research, and health care. Each year, it has over 1,100 medical students and 2,000 postgraduate students undertaking coursework and research-training programs. History Sydney Medical School was established in 1856 as ''The University of Sydney Faculty of Medicine'' by a group of University of Edinburgh Medical School graduates, Thomas Peter Anderson Stuart, Charles Nicholson and Alexander McCormick. Sydney Medical Program Sydney Medical School offers a four-year graduate medi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Columbia University Mailman School Of Public Health
The Joseph L. Mailman School of Public Health is the public health graduate school of Columbia University. Located on the Columbia University Medical Center campus in the Washington Heights neighborhood of Manhattan, New York City, the school is recognized by the Council on Education for Public Health. Founded in 1922 as the DeLamar Institute of Public Health, it is one of the oldest public health schools in the United States. It became an official school within Columbia University in 1945. In 1999, following a $33 million grant from the Joseph L. Mailman Foundation, the school was renamed the Joseph L. Mailman School of Public Health. The Mailman School is considered a preeminent school of public health in the United States, and is consistently ranked among the top in the nation by the '' U.S. News & World Report''. Admission to the school is highly selective and has traditionally drawn a very international student body. , the school enrolls over 1,600 students and is one of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Edinburgh
The University of Edinburgh ( sco, University o Edinburgh, gd, Oilthigh Dhùn Èideann; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Granted a royal charter by King James VI in 1582 and officially opened in 1583, it is one of Scotland's four ancient universities and the sixth-oldest university in continuous operation in the English-speaking world. The university played an important role in Edinburgh becoming a chief intellectual centre during the Scottish Enlightenment and contributed to the city being nicknamed the " Athens of the North." Edinburgh is ranked among the top universities in the United Kingdom and the world. Edinburgh is a member of several associations of research-intensive universities, including the Coimbra Group, League of European Research Universities, Russell Group, Una Europa, and Universitas 21. In the fiscal year ending 31 July 2021, it had a total income of £1.176 billion, of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Scripps Research Institute
Scripps Research, previously known as The Scripps Research Institute (TSRI), is a nonprofit American medical research facility that focuses on research and education in the biomedical sciences. Headquartered in San Diego, California, the institute has over 170 laboratories employing 2,100 scientists, technicians, graduate students, and administrative and other staff, making it the largest private, non-profit biomedical research organization in the United States and among the largest in the world. The institute holds over 1,100 patents, has produced 11 FDA-approved therapeutics, and has generated over 50 spin-off companies. According to the 2017 Nature Innovation Index, Scripps Research is the #1 most influential research institution in the world. The Scripps Research graduate program is ranked 9th nationally in the biological sciences, 6th for organic chemistry, and 6th for biochemistry. In 2022, their Jupiter, FL campus became a part of the University of Florida. Jupiter-based ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virus
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material, i. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coronavirus
Coronaviruses are a group of related RNA viruses that cause diseases in mammals and birds. In humans and birds, they cause respiratory tract infections that can range from mild to lethal. Mild illnesses in humans include some cases of the common cold (which is also caused by other viruses, predominantly rhinoviruses), while more lethal varieties can cause SARS, MERS and COVID-19, which is causing the ongoing pandemic. In cows and pigs they cause diarrhea, while in mice they cause hepatitis and encephalomyelitis. Coronaviruses constitute the subfamily ''Orthocoronavirinae'', in the family ''Coronaviridae'', order '' Nidovirales'' and realm '' Riboviria''. They are enveloped viruses with a positive-sense single-stranded RNA genome and a nucleocapsid of helical symmetry. The genome size of coronaviruses ranges from approximately 26 to 32 kilobases, one of the largest among RNA viruses. They have characteristic club-shaped spikes that project from their surface, which in electr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ron Fouchier
Ronaldus (Ron) Adrianus Maria Fouchier (born 13 October 1966) is a Dutch virologist who is Deputy head of the Erasmus MC Department of Viroscience, headed by Prof. Marion Koopmans. Notability Fouchier is notable for his research on respiratory viruses of humans and animals, antigenic drift, and influenza virus zoonoses, transmission and pandemics. His team contributed substantially to the identification and characterization of various “new” viruses, such as human metapneumovirus, human coronavirus NL63, SARS coronavirus, MERS coronavirus, and influenza A virus subtype H16. Fouchier is elected member of the Royal Dutch Academy of Sciences (KNAW), the Royal Holland Society of Sciences and Humanities The Koninklijke Hollandsche Maatschappij der Wetenschappen (Royal Holland Society of Sciences and Humanities), located on the east side of the Spaarne in downtown Haarlem, Netherlands, was established in 1752 and is the oldest society for the scie ... (KHMW) and Academi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
