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Preventive Mastectomy
A preventive mastectomy or prophylactic mastectomy is an elective operation to remove the breasts so that the risk of breast cancer is reduced. Indications The procedure is a surgical option for individuals who are at high risk for the development of breast cancer. Women who had a bilateral mastectomy in 2013 were about 10 years younger than those who had a unilateral mastectomy. This preventive operation pertains to women with these characteristics: * BRCA1 or BRCA2 mutation carriers; this is the main indication for bilateral prophylactic mastectomy. * Cancer in one breast and a family history of breast cancer. * Family history of breast cancer. The genetic risk can be passed down through the mother’s or father’s side. * Radiation therapy to the chest before the age of 30. * Presence of lobular carcinoma in situ. * Having dense breasts or breasts with diffuse microcalcification, as the screening for breast cancer is made difficult. Discussions and decision should be made ...
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Elective Surgery
Elective surgery or elective procedure (from the la, eligere, meaning to choose) is surgery that is scheduled in advance because it does not involve a medical emergency. Semi-elective surgery is a surgery that must be done to preserve the patient's life, but does not need to be performed immediately. By contrast, an urgent surgery is one that can wait until the patient is medically stable, but should generally be done within 2 days, and an emergency surgery is one that must be performed without delay; the patient has no choice other than immediate surgery if permanent disability or death is to be avoided. Types Most surgeries necessary for medical reasons are elective, that is, scheduled at a time to suit the surgeon, hospital, and patient. These include inguinal hernia surgery, cataract surgery, mastectomy for breast cancer, and the donation of a kidney by a living donor. Elective surgeries include all optional surgeries performed for non-medical reasons. This includes cosmet ...
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New York Times
''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid digital media, digital subscribers. It also is a producer of popular podcasts such as ''The Daily (podcast), The Daily''. Founded in 1851 by Henry Jarvis Raymond and George Jones (publisher), George Jones, it was initially published by Raymond, Jones & Company. The ''Times'' has won List of Pulitzer Prizes awarded to The New York Times, 132 Pulitzer Prizes, the most of any newspaper, and has long been regarded as a national "newspaper of record". For print it is ranked List of newspapers by circulation, 18th in the world by circulation and List of newspapers in the United States, 3rd in the U.S. The paper is owned by the New York Times Company, which is Public company, publicly traded. It has been governed by the Sulzberger family since 189 ...
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Obstetrical And Gynaecological Procedures
Obstetrics is the field of study concentrated on pregnancy, childbirth and the postpartum period. As a medical specialty, obstetrics is combined with gynecology under the discipline known as obstetrics and gynecology (OB/GYN), which is a surgical field. Main areas Prenatal care Prenatal care is important in screening for various complications of pregnancy. This includes routine office visits with physical exams and routine lab tests along with telehealth care for women with low-risk pregnancies: Image:Ultrasound_image_of_a_fetus.jpg, 3D ultrasound of fetus (about 14 weeks gestational age) Image:Sucking his thumb and waving.jpg, Fetus at 17 weeks Image:3dultrasound 20 weeks.jpg, Fetus at 20 weeks First trimester Routine tests in the first trimester of pregnancy generally include: * Complete blood count * Blood type ** Rh-negative antenatal patients should receive RhoGAM at 28 weeks to prevent Rh disease. * Indirect Coombs test (AGT) to assess risk of hemolytic disea ...
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Breast Surgery
Breast surgery is a form of surgery performed on the breast. Types Types include: *Breast reduction surgery *Augmentation mammoplasty *Mastectomy *Lumpectomy *Breast-conserving surgery, a less radical cancer surgery than mastectomy *Mastopexy, or breast lift surgery * Surgery for breast abscess, including incision and drainage as well as excision of lactiferous ducts * Surgical breast biopsy * Microdochectomy (removal of a lactiferous duct) Complications After surgical intervention to the breast, complications may arise related to wound healing. As in other types of surgery, hematoma (post-operative bleeding), seroma (fluid accumulation), or incision-site breakdown (wound infection) may occur. Breast hematoma due to an operation will normally resolve with time but should be followed up with more detailed evaluation if it does not. Breast abscess can occur as post-surgical complication, for example after cancer treatment or reduction mammaplasty.Noel Weidner, Chapter ''Infectio ...
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Breast Cancer
Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. In those with distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or yellow skin. Risk factors for developing breast cancer include obesity, a lack of physical exercise, alcoholism, hormone replacement therapy during menopause, ionizing radiation, an early age at first menstruation, having children late in life or not at all, older age, having a prior history of breast cancer, and a family history of breast cancer. About 5–10% of cases are the result of a genetic predisposition inherited from a person's parents, including BRCA1 and BRCA2 among others. Breast cancer most commonly develops in cells from the lining of milk ducts and the lobules that supply these ...
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Angelina Jolie
Angelina Jolie (; born Angelina Jolie Voight; June 4, 1975) is an American actress, filmmaker, humanitarian and former Special Envoy to the UN High Commissioner for Refugees. The recipient of numerous accolades, including an Academy Award and three Golden Globe Awards, she has been named Hollywood's highest-paid actress multiple times. Jolie made her screen debut as a child alongside her father, Jon Voight, in ''Lookin' to Get Out'' (1982), and her film career began in earnest a decade later with the low-budget production ''Cyborg 2'' (1993), followed by her first leading role in a major film, ''Hackers'' (1995). She starred in the critically acclaimed biographical cable films '' George Wallace'' (1997) and ''Gia'' (1998), and won an Academy Award for Best Supporting Actress for her performance in the 1999 drama '' Girl, Interrupted''. Her starring role as the titular video game heroine in '' Lara Croft: Tomb Raider'' (2001) established her as a leading Hollywood actress ...
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Christina Applegate
Christina Applegate (born November 25, 1971) is an American actress. As a child actress, she gained recognition for starring as Kelly Bundy in the Fox sitcom '' Married... with Children'' (1987–1997). Applegate established a successful film and television career in her adult years, winning a Primetime Emmy Award from seven nominations as well as nominations for four Golden Globe Awards and a Tony Award. Applegate starred in the title role of the NBC sitcom ''Jesse'' (1998–2000), which earned her a Golden Globe Award nomination. She received a Primetime Emmy Award for her guest role in the NBC sitcom ''Friends'' (2002–2003). For her role in the Broadway revival of ''Sweet Charity'' (2005), she earned a nomination for the Tony Award for Best Actress in a Musical. She went on to star in the ABC sitcom ''Samantha Who?'' (2007–2009), for which she received two Primetime Emmy Award and Golden Globe Award nominations; the NBC sitcom '' Up All Night'' (2011–2012); and the Netfl ...
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Newsweek
''Newsweek'' is an American weekly online news magazine co-owned 50 percent each by Dev Pragad, its president and CEO, and Johnathan Davis (businessman), Johnathan Davis, who has no operational role at ''Newsweek''. Founded as a weekly print magazine in 1933, it was widely distributed during the 20th century, and had many notable editors-in-chief. The magazine was acquired by The Washington Post Company in 1961, and remained under its ownership until 2010. Revenue declines prompted The Washington Post Company to sell it, in August 2010, to the audio pioneer Sidney Harman for a purchase price of one dollar and an assumption of the magazine's liabilities. Later that year, ''Newsweek'' merged with the news and opinion website ''The Daily Beast'', forming The Newsweek Daily Beast Company. ''Newsweek'' was jointly owned by the estate of Harman and the diversified American media and Internet company IAC (company), IAC. ''Newsweek'' continued to experience financial difficulties, whic ...
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Lifestyle (sociology)
Lifestyle is the interests, opinions, behaviours, and behavioural orientations of an individual, group, or culture. The term was introduced by Austrian psychologist Alfred Adler in his 1929 book, ''The Case of Miss R.'', with the meaning of "a person's basic character as established early in childhood". The broader sense of lifestyle as a "way or style of living" has been documented since 1961. Lifestyle is a combination of determining intangible or tangible factors. Tangible factors relate specifically to demographic variables, i.e. an individual's demographic profile, whereas intangible factors concern the psychological aspects of an individual such as personal values, preferences, and outlooks. A rural environment has different lifestyles compared to an urban metropolis. Location is important even within an urban scope. The nature of the neighborhood in which a person resides affects the set of lifestyles available to that person due to differences between various neighborhoods ...
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Oophorectomy
Oophorectomy (; from Greek , , 'egg-bearing' and , , 'a cutting out of'), historically also called ''ovariotomy'' is the surgical removal of an ovary or ovaries. The surgery is also called ovariectomy, but this term is mostly used in reference to animals, e.g. the surgical removal of ovaries from laboratory animals. Removal of the ovaries of females is the biological equivalent of castration of males; the term ''castration'' is only occasionally used in the medical literature to refer to oophorectomy of women. In veterinary medicine, the removal of ovaries and uterus is called ovariohysterectomy (spaying) and is a form of sterilization. The first reported successful human oophorectomy was carried out by (Sir) Sydney Jones at Sydney Infirmary, Australia, in 1870. Partial oophorectomy or ovariotomy is a term sometimes used to describe a variety of surgeries such as ovarian cyst removal, or resection of parts of the ovaries. This kind of surgery is fertility-preserving, although ...
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Exemestane
Exemestane, sold under the brand name Aromasin among others, is a medication used to treat breast cancer. It is a member of the class of antiestrogens known as aromatase inhibitors. Some breast cancers require estrogen to grow. Those cancers have estrogen receptors (ERs), and are called ER-positive. They may also be called estrogen-responsive, hormonally-responsive, or hormone-receptor-positive. Aromatase is an enzyme that synthesizes estrogen. Aromatase inhibitors block the synthesis of estrogen. This lowers the estrogen level, and slows the growth of cancers. Medical uses Exemestane is indicated for the adjuvant treatment of postmenopausal women with estrogen-receptor positive early breast cancer who have received two to three years of tamoxifen and are switched to it for completion of a total of five consecutive years of adjuvant hormonal therapy. US FDA approval was in October 1999. Exemestane is also indicated for the treatment of advanced breast cancer in postmenopausal wo ...
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Raloxifen
Raloxifene, sold under the brand name Evista among others, is a medication used to prevent and treat osteoporosis in postmenopausal women and those on glucocorticoids. For osteoporosis it is less preferred than bisphosphonates. It is also used to reduce the risk of breast cancer in those at high risk. It is taken by mouth. Common side effects include hot flashes, leg cramps, swelling, and joint pain. Severe side effects may include blood clots and stroke. Use during pregnancy may harm the baby. The medication may worsen menstrual symptoms. Raloxifene is a selective estrogen receptor modulator (SERM) and therefore a mixed agonist–receptor antagonist, antagonist of the estrogen receptor (ER). It has estrogen (medication), estrogenic effects in bone and antiestrogenic effects in the breasts and uterus. Raloxifene was approved for medical use in the United States in 1997. It is available as a generic drug, generic medication. In 2020, it was the 292nd most commonly prescribed me ...
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