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Predimed
PREDIMED ( (Prevention with Mediterranean Diet)) was a large Spanish primary prevention trial which included 7,447 Spanish participants (55–80 years, 58% women) who were at high risk for cardiovascular disease, but otherwise healthy (initially free of cardiovascular disease). They were randomly assigned to receive interventions with intensive education to one of three diets: # Mediterranean diet supplemented with extra-virgin olive oil. # Mediterranean diet supplemented with nuts. # Control diet encouraging low-fat food items. The trial was planned for six years, but it was terminated early after a median follow-up of 4.8 years, and demonstrated that both Mediterranean diet groups reached a statistically significant reduction in the rate of the composite cardiovascular primary end-point of myocardial infarction, stroke, or cardiovascular death. This corresponded to an absolute reduction in 3 less cardiovascular events per 1000 patient-years, or a 30% relative risk reduction. O ...
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Miguel Ángel Martínez-González
Miguel Ángel Martínez-González (born in 1957 in Málaga, Spain) is a Spanish medical doctor, epidemiologist, professor, and nutrition researcher He has been often a visiting scholar at Harvard T.H. Chan School of Public Health (Dept. Nutrition). Martínez-González was the Founder and Chair (until September 2022) of the Department of Preventive Medicine and Public Health at University of Navarra at the Medical School. He was also the Principal Investigator of an Advanced Research Grant of the European Research Council for funding the PREDIMED-Plus trial. Martínez-González has been also the Founder and 'Principal Investigator' (until June 2022) of thSUN cohort study and he was (2006-2013) the Coordinator of the several centers included in the PREDIMED Network (a large clinical trial assessing the effects of a Mediterranean diet The Mediterranean diet is a diet inspired by the eating habits of people who live near the Mediterranean Sea. When initially formulated in the 1 ...
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Mediterranean Diet
The Mediterranean diet is a diet inspired by the eating habits of people who live near the Mediterranean Sea. When initially formulated in the 1960s, it drew on the cuisines of Greece, Italy, France and Spain. In decades since, it has also incorporated other Mediterranean cuisines, such as those in Turkey, the Balkans, Lebanon, Syria, North Africa and Portugal. The principal aspects of this diet include proportionally high consumption of unprocessed cereals, legumes, olive oil, fruits, and vegetables, and moderate consumption of fish, dairy products (mostly cheese and yogurt), and meat products. Olive oil has been studied as a potential health factor for reducing all-cause mortality and the risk of chronic diseases. The Mediterranean diet is associated with a reduction in all-cause mortality in observational studies. There is evidence that the Mediterranean diet lowers the risk of heart disease and early death. The American Heart Association and American Diabetes Association r ...
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Frank Hu
Frank B. Hu (; born 1966) is a Chinese American nutrition and diabetes researcher. He is Chair of the Department of Nutrition and the Fredrick J. Stare Professor of Nutrition and Epidemiology at the Harvard T.H. Chan School of Public Health, and Professor of Medicine at the Harvard Medical School. Hu is also the Director of the Epidemiology and Genetics Core of the Boston Obesity Nutrition Research Center; and co-director of the Program in Obesity Epidemiology and Prevention at the Harvard T.H. Chan School of Public Health. Hu was elected into the National Academy of Medicine (NAM) in 2015, one of the highest honors in the fields of health and medicine. Education A native of Hubei Province, China, Hu received his M.D. from the Tongji Medical University (now Tongji Medical College of the Huazhong University of Science and Technology) in Wuhan in 1988, and his Ph.D. from the University of Illinois at Chicago in 1996. Research Hu's research has focused on diet/lifestyle, metaboli ...
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Research In Spain
Research is " creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, econom ...
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Nutritional Science
Nutritional science (also nutrition science, sometimes short ''nutrition'', dated trophology) is the science that studies the physiological process of nutrition (primarily human nutrition), interpreting the nutrients and other substances in food in relation to maintenance, growth, reproduction, health and disease of an organism. History Before nutritional science emerged as an independent study disciplines, mainly chemists worked in this area. The chemical composition of food was examined. Macronutrients, especially protein, fat and carbohydrates, have been the focus components of the study of (human) nutrition since the 19th century. Until the discovery of vitamins and vital substances, the quality of nutrition was measured exclusively by the intake of nutritional energy. The early years of the 20th century were summarized by Kenneth John Carpenter in his ''Short History of Nutritional Science'' as "the vitamin era". The first vitamin was isolated and chemically defined in 19 ...
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Health Effects Of Food And Nutrition
Health, according to the World Health Organization, is "a state of complete physical, mental and social well-being and not merely the absence of disease and infirmity".World Health Organization. (2006)''Constitution of the World Health Organization''– ''Basic Documents'', Forty-fifth edition, Supplement, October 2006. A variety of definitions have been used for different purposes over time. Health can be promoted by encouraging healthful activities, such as regular physical exercise and adequate sleep, and by reducing or avoiding unhealthful activities or situations, such as smoking or excessive stress. Some factors affecting health are due to individual choices, such as whether to engage in a high-risk behavior, while others are due to structural causes, such as whether the society is arranged in a way that makes it easier or harder for people to get necessary healthcare services. Still, other factors are beyond both individual and group choices, such as genetic disorders. ...
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