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Post-exertional Malaise
Post-exertional malaise (PEM) is a worsening of chronic fatigue syndrome symptoms that occurs after exertion. PEM involves increased fatigue, and an exacerbation of other symptoms. PEM is often severe enough to be disabling, and is triggered by ordinary activities that healthy people tolerate. Post-exertional malaise typically begins 12–48 hours after the activity that triggers it, and lasts for days, but this is highly variable. Management of PEM is symptomatic, and patients are recommended to pace their activities to avoid triggering PEM. Description Post-exertional malaise involves fatigue, and is of such a severity that it impacts a person's functioning. Other symptoms that may be experienced during PEM include cognitive impairment, flu-like symptoms, pain, weakness or trouble sleeping. While typically cast as a worsening of existing symptoms, patients may experience some symptoms exclusively during PEM. Patients often describe PEM as "crash," "relapse," or "setback." PEM ...
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Chronic Fatigue Syndrome
Chronic fatigue syndrome (CFS), also called myalgic encephalomyelitis (ME) or ME/CFS, is a complex, debilitating, long-term medical condition. The causes and mechanisms of the disease are not fully understood. Distinguishing core symptoms are lengthy exacerbations or flare-ups of the illness following ordinary minor physical or mental activity, known as post-exertional malaise (PEM); greatly diminished capacity to accomplish tasks that were routine before the illness; and sleep disturbances. Orthostatic intolerance (difficulty sitting and standing upright) and cognitive dysfunction are also diagnostic. Frequently and variably, other common symptoms occur involving numerous body systems, and chronic pain is common. The unexplained and often incapacitating fatigue in CFS is different from that caused by normal strenuous ongoing exertion, is not significantly relieved by rest, and is not due to a previous medical condition. Diagnosis is based on the person's symptoms because no c ...
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Long Covid
Long COVID or long-haul COVID (also known as post-COVID-19 syndrome, post-COVID-19 condition, post-acute sequelae of COVID-19 (PASC), or chronic COVID syndrome (CCS)) is a condition characterized by long-term health problems persisting or appearing after the typical recovery period of COVID-19. Although studies into long COVID are under way, there is no consensus on the definition of the term. Long COVID has been described as having the potential to affect nearly every organ system, causing further conditions (sequelae) including respiratory system disorders, nervous system and neurocognitive disorders, mental health disorders, metabolic disorders, cardiovascular disorders, gastrointestinal disorders, musculoskeletal pain, and anemia. The most commonly reported symptoms of long COVID are fatigue and memory problems. Many other symptoms have also been reported, including malaise, headaches, shortness of breath, anosmia ( loss of smell), parosmia (distorted smell), muscle we ...
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Chronic Fatigue Syndrome
Chronic fatigue syndrome (CFS), also called myalgic encephalomyelitis (ME) or ME/CFS, is a complex, debilitating, long-term medical condition. The causes and mechanisms of the disease are not fully understood. Distinguishing core symptoms are lengthy exacerbations or flare-ups of the illness following ordinary minor physical or mental activity, known as post-exertional malaise (PEM); greatly diminished capacity to accomplish tasks that were routine before the illness; and sleep disturbances. Orthostatic intolerance (difficulty sitting and standing upright) and cognitive dysfunction are also diagnostic. Frequently and variably, other common symptoms occur involving numerous body systems, and chronic pain is common. The unexplained and often incapacitating fatigue in CFS is different from that caused by normal strenuous ongoing exertion, is not significantly relieved by rest, and is not due to a previous medical condition. Diagnosis is based on the person's symptoms because no c ...
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Cognitive Deficit
Cognitive deficit is an inclusive term to describe any characteristic that acts as a barrier to the cognition process. The term may describe * deficits in overall intelligence (as with intellectual disabilities), * specific and restricted deficits in cognitive abilities (such as in learning disorders like dyslexia), * neuropsychological deficits (such as in attention, working memory or executive function), * or it may describe drug-induced impairment in cognition and memory (such as that seen with alcohol, glucocorticoids, and the benzodiazepines.) Cause It usually refers to a durable characteristic, as opposed to altered level of consciousness, which may be acute and reversible. Cognitive deficits may be inborn or caused by environmental factors such as brain injuries, neurological disorders, or mental illness. Screening Screening for cognitive impairment in those over the age of 65 without symptoms is of unclear benefit versus harm as of 2020. In a large population-based c ...
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Journal Of Internal Medicine
The ''Journal of Internal Medicine'' is a monthly peer-reviewed medical journal covering all aspects of internal medicine. It was established in 1863 and is published by Wiley-Blackwell on behalf of the Association for the Publication of the Journal of Internal Medicine. The editor-in-chief is Bo Angelin (Karolinska Institute). History The journal was established in 1863 as ''Medicinskt Archiv'' by Axel Key (Karolinska Institute). It covered the broad field of medicine, but accepted only contributions from Sweden written in Swedish. However, it soon became more international and in 1869 it was renamed ''Nordiskt Medicinskt Arkiv'', accepting articles from all Nordic countries in Swedish, Danish, and Norwegian, with abstracts in German. In 1901, the journal was divided into two sections, one for internal medicine and one for surgery. The two parts were in 1919 fully separated into ''Acta Medica Scandinavica'' and ''Acta Chirurgica Scandinavica''. ''Acta Medica Scandinavica'' cov ...
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Long COVID
Long COVID or long-haul COVID (also known as post-COVID-19 syndrome, post-COVID-19 condition, post-acute sequelae of COVID-19 (PASC), or chronic COVID syndrome (CCS)) is a condition characterized by long-term health problems persisting or appearing after the typical recovery period of COVID-19. Although studies into long COVID are under way, there is no consensus on the definition of the term. Long COVID has been described as having the potential to affect nearly every organ system, causing further conditions (sequelae) including respiratory system disorders, nervous system and neurocognitive disorders, mental health disorders, metabolic disorders, cardiovascular disorders, gastrointestinal disorders, musculoskeletal pain, and anemia. The most commonly reported symptoms of long COVID are fatigue and memory problems. Many other symptoms have also been reported, including malaise, headaches, shortness of breath, anosmia ( loss of smell), parosmia (distorted smell), muscle we ...
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Cardinal Sign (pathology)
Signs and symptoms are the observed or detectable signs, and experienced symptoms of an illness, injury, or condition. A sign for example may be a higher or lower temperature than normal, raised or lowered blood pressure or an abnormality showing on a medical scan. A symptom is something out of the ordinary that is experienced by an individual such as feeling feverish, a headache or other pain or pains in the body. Signs and symptoms Signs A medical sign is an objective observable indication of a disease, injury, or abnormal physiological state that may be detected during a physical examination, examining the patient history, or diagnostic procedure. These signs are visible or otherwise detectable such as a rash or bruise. Medical signs, along with symptoms, assist in formulating diagnostic hypothesis. Examples of signs include elevated blood pressure, nail clubbing of the fingernails or toenails, staggering gait, and arcus senilis and arcus juvenilis of the eyes. Indicatio ...
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Clinical Descriptions Of Chronic Fatigue Syndrome
Clinical descriptions of chronic fatigue syndrome (CFS) vary. Different groups have produced sets of diagnostic criteria that share many similarities. The biggest differences between criteria are whether post-exertional malaise (PEM) is required, and the number of symptoms needed. Aspects of the condition are controversial, with disagreements over etiology, pathophysiology, treatment and naming between medical practitioners, researchers, patients and advocacy groups. Furthermore, diagnosing CFS can be difficult due to several factors, including lack of a standard test and non-specific symptoms. Subgroup analysis suggests that, depending on the applied definition, CFS may represent a variety of conditions rather than a single disease entity. Definitions 2015 IOM criteria The IOM criteria come from the IOM's 2015 report on CFS, and the CDC currently uses this definition. The IOM criteria require the following three symptoms: * Severe, disabling fatigue of new onset * Post-exer ...
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Pacing (activity Management)
Pacing is an activity management technique for managing a long-term health condition or disability, aiming to maximize what a person can do while reducing, or at least controlling, any symptoms that restrict activity. Pacing is commonly used to help manage conditions that cause chronic pain or chronic fatigue. Aims Pacing aims to manage symptoms by avoiding the "boom and bust" cycle that is common among people exceeding their current, limited capacities. This often leads to being forced to stop their activities as a result of pain, fatigue or other symptoms, and then requiring a large amount of rest before being able to resume their activity. The cycle then repeats. Elements of pacing There is no consensus regarding what elements are part of pacing. Pacing typically involves: * planning activities in advance * taking regular rest breaks * choosing activities based on available energy * prioritizing activities Uses Pacing has been used to help manage a wide variety of differen ...
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