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Porcine Stress Syndrome
Porcine stress syndrome, also known as malignant hyperthermia or PSS, is a condition in pigs. It is characterised by hyperthermia triggered by stress, anaesthesia with halothane or intense exercise. PSS may appear as sudden death in pigs, often after transport. It is an inherited, autosomal recessive disorder due to a defective ryanodine receptor leading to huge calcium influx, muscle contracture and increase in metabolism. PSS can manifest itself in the abattoir as the production of Pale, Soft and Exudative meat due to a rapid fall in muscle pH and degradation of muscle proteins and structure. This meat is usually rejected after inspection. This disorder is most common in Landrace, Piétrain and crossbreeds of these breeds of pig. The genes may have been favoured in the past due to a larger muscle bulk in these breeds. However this is not standard protocol in developed countries these days. Clinical signs and diagnosis Truckloads or railcar loads of PSS-susceptible pigs may be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malignant Hyperthermia
Malignant hyperthermia (MH) is a type of severe reaction that occurs in response to particular medications used during General anaesthesia, general anesthesia, among those who are susceptible. Symptoms include tetany, muscle rigidity, hyperthermia, fever, and a tachycardia, fast heart rate. Complications can include rhabdomyolysis, muscle breakdown and hyperkalemia, high blood potassium. Most people who are susceptible to MH are generally unaffected when not exposed to triggering agents. Exposure to triggering agents (certain inhalational anaesthetic, volatile anesthetic agents or Suxamethonium chloride, succinylcholine) can lead to the development of MH in those who are susceptible. Susceptibility can occur due to at least six genetic mutations, with the most common one being of the RYR1 gene. These genetic variations are often inherited from a person's parents in an Dominance (genetics), autosomal dominant manner. The condition may also occur as a new mutation or be associated w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pyrexia
Fever, also referred to as pyrexia, is defined as having a temperature above the normal range due to an increase in the body's temperature set point. There is not a single agreed-upon upper limit for normal temperature with sources using values between in humans. The increase in set point triggers increased muscle contractions and causes a feeling of cold or chills. This results in greater heat production and efforts to conserve heat. When the set point temperature returns to normal, a person feels hot, becomes flushed, and may begin to sweat. Rarely a fever may trigger a febrile seizure, with this being more common in young children. Fevers do not typically go higher than . A fever can be caused by many medical conditions ranging from non-serious to life-threatening. This includes viral, bacterial, and parasitic infections—such as influenza, the common cold, meningitis, urinary tract infections, appendicitis, Lassa, COVID-19, and malaria. Non-infectious causes include ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dantrolene
Dantrolene sodium, sold under the brand name Dantrium among others, is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It achieves this by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors. It is the primary drug used for the treatment and prevention of malignant hyperthermia, a rare, life-threatening disorder triggered by general anesthesia or drugs. It is also used in the management of neuroleptic malignant syndrome, muscle spasticity (e.g. after strokes, in paraplegia, cerebral palsy, or patients with multiple sclerosis), and poisoning by 2,4-dinitrophenol or by the related compounds dinoseb and dinoterb. The most frequently occurring side effects include drowsiness, dizziness, weakness, general malaise, fatigue, and diarrhea. It is marketed by Par Pharmaceuticals LLC as Dantrium (in North America) and by Norgine BV as Dantrium, Dantamacrin, or Dantrolen (in Europe). A hospital ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glucocorticoids
Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that is present in almost every vertebrate animal cell. The name "glucocorticoid" is a portmanteau (glucose + cortex + steroid) and is composed from its role in regulation of glucose metabolism, synthesis in the adrenal cortex, and its steroidal structure (see structure below). Glucocorticoids are part of the feedback mechanism in the immune system, which reduces certain aspects of immune function, such as inflammation. They are therefore used in medicine to treat diseases caused by an overactive immune system, such as allergies, asthma, autoimmune diseases, and sepsis. Glucocorticoids have many diverse (pleiotropic) effects, including potentially harmful side effects. They also interfere with some of the abnormal mechanisms in cancer cells, so they are used in high doses to tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Why We Love Dogs, Eat Pigs, And Wear Cows
''Why We Love Dogs, Eat Pigs, and Wear Cows: An Introduction to Carnism'' is a 2009 book by American social psychologist Melanie Joy about the belief system and psychology of meat eating, or " carnism". Joy coined the term ''carnism'' in 2001 and developed it in her doctoral dissertation in 2003.Kool, V. K.; Agrawal, Rita (2009). The Psychology of Nonkilling. In Joám Evans Pim (Ed.), ''Toward a Nonkilling Paradigm'' (pp. 349-370). Center for Global Nonkilling. .Joy, Melanie (2003). ''Psychic numbing and meat consumption: The Psychology of carnism'' (Doctoral dissertation). Carnism is a subset of speciesism, and contrasts with ethical veganism, the moral commitment to abstain from consuming or using meat and other animal products. In 2020, an anniversary edition of the book was published by publisher Red Wheel. Background Joy, a social psychologist and author, was concerned about linguistic bias inherent in terms like ''carnivore'', which were inaccurate and failed to account fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Post-traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a mental and behavioral disorder that can develop because of exposure to a traumatic event, such as sexual assault, warfare, traffic collisions, child abuse, domestic violence, or other threats on a person's life. Symptoms may include disturbing thoughts, feelings, or dreams related to the events, mental or physical distress to trauma-related cues, attempts to avoid trauma-related cues, alterations in the way a person thinks and feels, and an increase in the fight-or-flight response. These symptoms last for more than a month after the event. Young children are less likely to show distress but instead may express their memories through play. A person with PTSD is at a higher risk of suicide and intentional self-harm. Most people who experience traumatic events do not develop PTSD. People who experience interpersonal violence such as rape, other sexual assaults, being kidnapped, stalking, physical abuse by an intimate partner, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Melanie Joy
Melanie Joy (born September 2, 1966) is an American social psychologist and author, primarily notable for coining and promulgating the term carnism. She is the founding president of nonprofit advocacy group Beyond Carnism, previously known as Carnism Awareness & Action Network (CAAN), as well as a former professor of psychology and sociology at the University of Massachusetts Boston. She has published the books ''Strategic Action for Animals'', ''Why We Love Dogs, Eat Pigs, and Wear Cows'' and ''Beyond Beliefs''. Background Joy received her M.Ed. from the Harvard Graduate School of Education, and her Ph.D. in psychology from the Saybrook Graduate School. At age 23, while a student at Harvard, she contracted a food-borne disease from a tainted hamburger and was hospitalized, which led her to become a vegetarian. In a speech related by Indian cabinet minister Maneka Gandhi, Joy recalled how her dietary choice, made for non-moral reasons, transformed her perspective on the treatment ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polymerase Chain Reaction
The polymerase chain reaction (PCR) is a method widely used to rapidly make millions to billions of copies (complete or partial) of a specific DNA sample, allowing scientists to take a very small sample of DNA and amplify it (or a part of it) to a large enough amount to study in detail. PCR was invented in 1983 by the American biochemist Kary Mullis at Cetus Corporation; Mullis and biochemist Michael Smith (chemist), Michael Smith, who had developed other essential ways of manipulating DNA, were jointly awarded the Nobel Prize in Chemistry in 1993. PCR is fundamental to many of the procedures used in genetic testing and research, including analysis of Ancient DNA, ancient samples of DNA and identification of infectious agents. Using PCR, copies of very small amounts of DNA sequences are exponentially amplified in a series of cycles of temperature changes. PCR is now a common and often indispensable technique used in medical laboratory research for a broad variety of applications ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PSS Breeding Practices
PSS may refer to: Businesses and organizations Government and military organizations *Palestinian Security Services, the armed forces and intelligence agencies of the State of Palestine *Parliament Security Services, in charge of providing security to the Parliament of India *Presidential Security Service (South Korea), a South Korean close protection agency Political parties *Sammarinese Socialist Party ( it, Partito Socialista Sammarinese, link=no), San Marino * Senegalese Socialist Party (french: Parti Socialiste Sénégalais, link=no) * Strength of Serbia Movement (''Pokret snaga Srbije''), a political party in Serbia Schools Canada *Parkland Secondary School, North Saanich, Victoria, British Columbia *Penetanguishene Secondary School, Simcoe County District School Board, Ontario *Penticton Secondary School, Penticton, British Columbia *Pinetree Secondary School, Coquitlam, British Columbia *Parkview Secondary School, Hamilton, Ontario Elsewhere * Pak Shama School, Doha, Qata ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hyperthermia
Hyperthermia, also known simply as overheating, is a condition in which an individual's body temperature is elevated beyond normal due to failed thermoregulation. The person's body produces or absorbs more heat than it dissipates. When extreme temperature elevation occurs, it becomes a medical emergency requiring immediate treatment to prevent disability or death. Almost half a million deaths are recorded every year from hyperthermia. The most common causes include heat stroke and adverse reactions to drugs. Heat stroke is an body temperature, acute temperature elevation caused by exposure to excessive heat, or combination of heat and humidity, that overwhelms the heat-regulating mechanisms of the body. The latter is a relatively rare side effect of many drugs, particularly those that affect the central nervous system. Malignant hyperthermia is a rare complication of some types of general anesthesia. Hyperthermia can also be caused by a traumatic brain injury. Hyperthermia di ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Piétrain
Piétrain () is a Belgian breed of domestic pig. It is native to Wallonia, and takes its name from the village of Piétrain in the municipality of Jodoigne in Walloon Brabant, in northern Wallonia. It first appeared in about 1920, and received recognition as a breed in 1950. Its origins are not clear; it has been suggested that the farmers of Piétrain may have recognised, and selectively bred for, a genetic mutation causing muscular hypertrophy. From about 1960, the Piétrain was also reared in Germany, principally in Baden-Württemberg, Nordrhein-Westfalen and Schleswig-Holstein; it is used as a sire for cross-breeding. In the 1980s and 1990s, researchers at the faculty of veterinary medicine of the Université de Liège used cross-breeding with stress-resistant Large White stock to develop a Piétrain strain without the gene for porcine stress syndrome (also called malignant hypothermia), to which the original stock was particularly susceptible. Characteristics The P ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Danish Landrace Pig
The Danish Landrace, da, Hvid Dansk Landrace, italic=no, is a Danish breed of pig. It is of medium to large size, white in colour with a long body, fine hair, a long snout, and heavy drooping ears. There are two distinct varieties, the white (') and the piebald ('). History During the second half of the nineteenth century, Denmark became a major supplier of bacon to the United Kingdom: exports grew from 1000 tons per year in 1850 to in 1900; they grew still further in the twentieth century, reaching in 1932. From about 1865, and particularly between 1879 and 1896, breeding stock of the British Large White or Yorkshire breed was imported and cross-bred with local animals to supply the bacon trade. The cross of a Large White boar with a sow of the traditional Jutland breed was found to be particularly successful. In 1896 the Danish government drew up a national plan for pig production, under which the Large White x Jutland hybrid would become a new breed, the Danish Land ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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