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Poliosis
Poliosis (also called poliosis circumscripta), is the decrease or absence of melanin (or colour) in head hair, eyebrows, eyelashes or any other hairy area. It is popularly known as white forelock when it affects hair directly above the forehead. This condition can cause single or, less commonly, multiple white patches on the hair. Some mistake these white patches for simple birth marks. In poliosis there is decreased or absent melanin in the hair bulbs of affected hair follicles; the melanocytes of the skin are usually not affected.} Associated medical conditions Poliosis occurs in several genetic syndromes such as piebaldism, Waardenburg syndrome, neurofibromatosis type I, and tuberous sclerosis. It can also occur in conditions such as vitiligo, Vogt–Koyanagi–Harada disease, alopecia areata, sarcoidosis, and in association with neoplasms and some medications. Popular culture It is sometimes called a Mallen streak, after a fictional family with hereditary poliosis. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vogt–Koyanagi–Harada Disease
Vogt–Koyanagi–Harada disease (VKH) is a multisystem disease of presumed autoimmune disease, autoimmune cause that affects melanin-pigmented tissues. The most significant manifestation is bilateral, diffuse uveitis, which affects the eyes. VKH may variably also involve the inner ear, with effects on hearing, the skin, and the meninges of the central nervous system. Signs and symptoms Overview The disease is characterised by bilateral diffuse uveitis, with pain, redness and vision loss, blurring of vision. The eye symptoms may be accompanied by a varying constellation of systemic symptoms, such as auditory (tinnitus, vertigo, and hypoacusis), neurological (meningismus, with malaise, fever, headache, nausea, abdominal pain, stiffness of the neck and back, or a combination of these factors; meningitis, Cerebrospinal fluid, CSF pleocytosis, cranial nerve palsy, palsies, hemiparesis, transverse myelitis and ciliary ganglionitis), and cutaneous manifestations, including poli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Henson (comedian)
John Morris Henson (born July 11, 1967) is an American comedian, actor, and talk show host. He was the co-host of ABC's '' Wipeout'' with John Anderson, a prime-time game show that ran for 7 seasons. Biography Henson was born in Stamford, Connecticut, to Joe and Barbara (née Wright) Henson. He has four older brothers, one of whom is Dan Henson, the President and CEO of GE Capital, Americas. Another is Frank (Bubba) Henson, a teacher at St. Luke's School in New Canaan, Connecticut. He studied acting at Boston University, Circle in the Square, Playwrights Horizons and Three of Us Studios in New York City. He has starred in various theater productions such as ''Rosencrantz and Guildenstern Are Dead'', '' Conduct Unbecoming'', ''Heinous Crimes and Other Delights'', ''The Greenhouse Effect'' and ''Remote Evolution''. Henson was born with a white streak of hair on the right side of his head. As a result, he received the nickname "Skunk Boy" while hosting '' Talk Soup''. Henson ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Mallens
''The Mallens'' was a popular Granada Television adaptation of Catherine Cookson novels that ran for 13 episodes from 10 June 1979 to 3 July 1980. The series is based on ''The Mallen Streak'', ''The Mallen Girls'', and ''The Mallen Secret'' and ''The Mallen Curse''. Plot summary Mallen Streak The pivotal character is a ruthless 19th century Northumberland Squire, Thomas Mallen (played by John Hallam) of High Banks Hall, who has a genetic white streak (Poliosis) in his hair and fathers numerous illegitimate children, who all inherit the white streak and live disastrous lives. One of them is Donald Radlet (John Duttine), who stars in both ''The Mallen Streak'' and ''The Mallen Girls''. Thomas Mallen, penniless, mortgages his farming estate to make ends meet; he attempts to get his only legitimate son, Richard Mallen (David Rintoul) married to Fanny Armstrong, an unattractive girl with a rich father. Richard struggles to get Fanny to marry him, since they dislike each other, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Piebaldism
Piebaldism refers to the absence of mature melanin-forming cells (melanocytes) in certain areas of the skin and hair. It is a rare autosomal dominant disorder of melanocyte development.James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. . Common characteristics include a congenital white forelock, scattered normal pigmented and hypopigmented macules and a triangular shaped depigmented patch on the forehead. There is nevertheless great variation in the degree and pattern of presentation, even within affected families. In some cases, piebaldism occurs together with severe developmental problems, as in Waardenburg syndrome and Hirschsprung's disease. Piebaldism has been documented to occur in all races, and is found in nearly every species of mammal. The condition is very common in mice, rabbits, dogs, sheep, deer, cattle and horses—where selective breeding has increased the incidence of the mutation—b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
X-Men
The X-Men are a superhero team appearing in American comic books published by Marvel Comics, first appearing in Uncanny X-Men, ''The X-Men'' #1 by artist/co-plotter Jack Kirby and writer/editor Stan Lee in 1963. Although initially cancelled in 1970 due to low sales, following its Giant-Size X-Men, 1975 revival and subsequent direction under writer Chris Claremont, it became one of the most recognizable and successful franchises of Marvel Comics. They have appeared in numerous books, X-Men in television, television shows, the 20th Century Fox X-Men (film series), ''X-Men'' films, and List of video games featuring the X-Men, video games. The ''X-Men'' title may refer to the superhero team itself, X-Men (comic book), the eponymous comic series, or the broader franchise including List of X-Men comics, various solo titles and team books such as the New Mutants, Excalibur (comics), Excalibur, and X-Force. In the Marvel Universe, Mutant (Marvel Comics), mutants are humans who are born ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rogue (Marvel Comics)
Rogue is a character appearing in American comic books published by Marvel Comics, mostly in association with the X-Men. The character was created by Chris Claremont and Michael Golden, and first appeared in '' Avengers Annual'' #10 in 1981. In her comic book appearances, Rogue is portrayed as a mutant, a fictional subspecies of humans born with an "X-gene" that grants superhuman abilities. She is capable of absorbing the life force, attributes, memories, and superpowers of anyone through physical touch. Rogue is initially depicted as a reluctant supervillain, but she soon joins the X-Men as a superhero and has since endured as one of its most prominent members. A runaway from the fictional Caldecott County, Mississippi, Rogue is adopted by Mystique and inducted into the Brotherhood of Evil Mutants. She permanently absorbs Ms. Marvel's psyche and Kree powers and, fearing for her sanity, defects from the Brotherhood to join the X-Men. Although she eventually gains full control ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
X-Men (film)
''X-Men'' is a 2000 American superhero film directed by Bryan Singer and written by David Hayter from a story by Singer and Tom DeSanto. The film is based on the Marvel Comics superhero team of the same name, created by Stan Lee and Jack Kirby, and features an ensemble cast consisting of Patrick Stewart, Hugh Jackman, Ian McKellen, Halle Berry, Famke Janssen, James Marsden, Bruce Davison, Rebecca Romijn, Ray Park, Tyler Mane, and Anna Paquin. The film depicts a world where an unknown proportion of people are mutants, whose possession of superhuman powers makes them distrusted by normal humans. It focuses on mutants Wolverine and Rogue as they are brought into a conflict between two groups that have radically different approaches to bringing about the acceptance of mutant-kind: Charles Xavier's X-Men, and the Brotherhood of Mutants, led by Magneto. Development of ''X-Men'' began as far back as 1984 with Orion Pictures, with James Cameron and Kathryn Bigelow in discussions a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Magneto (Marvel Comics)
Magneto (; birth name: Max Eisenhardt; alias: Erik Lehnsherr and Magnus) is a fictional character appearing in American comic books published by Marvel Comics, commonly in association with the X-Men. Created by writer Stan Lee and artist/co-writer Jack Kirby, the character first appears in ''Uncanny X-Men, The X-Men'' #1 (cover-dated September 1963) as an adversary of the X-Men. The character is a powerful Mutant (Marvel Comics), mutant, one of a fictional subspecies of humanity born with superhuman abilities, who has the ability to generate and control magnetic fields. Magneto regards mutants as evolutionarily superior to humans and rejects the possibility of peaceful human-mutant coexistence; he initially aimed to conquer the world to enable mutants, whom he refers to as ''homo superior'', to replace humans as the dominant species. Writers have since fleshed out his origins and motivations, revealing him to be a Holocaust survivors, Holocaust survivor whose extreme methods ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
