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Pneumatic Institution
The Pneumatic Institution (also referred to as Pneumatic Institute) was a medical research facility in Bristol, England, in 1799–1802. It was established by physician and science writer Thomas Beddoes to study the medical effects of gases, known as factitious airs, that had recently been discovered. Humphry Davy headed the Institution's laboratory, examining the effects of laughing gas on himself and others, and James Watt designed much of the lab's equipment. History Preliminaries After Lavoisier had established the role of oxygen in animal respiration, members of the Lunar Society, such as Joseph Priestley (who had co-discovered oxygen), originated pneumatic chemistry, which eventually led to the establishment of the Pneumatic Institution. Georgiana, Duchess of Devonshire, who was unusually educated about Chemistry, visited Thomas Beddoes in his laboratory in Hope Square, Bristol, in December 1793. He had set it up earlier that year to study possible medical uses of the re ...
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Bristol Pneumatic Institute
Bristol () is a city, ceremonial county and unitary authority in England. Situated on the River Avon, it is bordered by the ceremonial counties of Gloucestershire to the north and Somerset to the south. Bristol is the most populous city in South West England. The wider Bristol Built-up Area is the eleventh most populous urban area in the United Kingdom. Iron Age hillforts and Roman villas were built near the confluence of the rivers Frome and Avon. Around the beginning of the 11th century, the settlement was known as (Old English: 'the place at the bridge'). Bristol received a royal charter in 1155 and was historically divided between Gloucestershire and Somerset until 1373 when it became a county corporate. From the 13th to the 18th century, Bristol was among the top three English cities, after London, in tax receipts. A major port, Bristol was a starting place for early voyages of exploration to the New World. On a ship out of Bristol in 1497, John Cabot, a Venetian, b ...
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6 Dowry Square, Bristol
6 (six) is the natural number following 5 and preceding 7. It is a composite number and the smallest perfect number. In mathematics Six is the smallest positive integer which is neither a square number nor a prime number; it is the second smallest composite number, behind 4; its proper divisors are , and . Since 6 equals the sum of its proper divisors, it is a perfect number; 6 is the smallest of the perfect numbers. It is also the smallest Granville number, or \mathcal-perfect number. As a perfect number: *6 is related to the Mersenne prime 3, since . (The next perfect number is 28.) *6 is the only even perfect number that is not the sum of successive odd cubes. *6 is the root of the 6-aliquot tree, and is itself the aliquot sum of only one other number; the square number, . Six is the only number that is both the sum and the product of three consecutive positive numbers. Unrelated to 6's being a perfect number, a Golomb ruler of length 6 is a "perfect ruler". Six is a con ...
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Royal Institution
The Royal Institution of Great Britain (often the Royal Institution, Ri or RI) is an organisation for scientific education and research, based in the City of Westminster. It was founded in 1799 by the leading British scientists of the age, including Henry Cavendish and its first president, George Finch. Its foundational principles were diffusing the knowledge of, and facilitating the general introduction of useful mechanical inventions and improvements, as well as enhancing the application of science to the common purposes of life (including through teaching, courses of philosophical lectures, and experiments). Much of the Institution's initial funding and the initial proposal for its founding were given by the Society for Bettering the Conditions and Improving the Comforts of the Poor, under the guidance of philanthropist Sir Thomas Bernard and American-born British scientist Sir Benjamin Thompson, Count Rumford. Since its founding it has been based at 21 Albemarle Street ...
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Typhus
Typhus, also known as typhus fever, is a group of infectious diseases that include epidemic typhus, scrub typhus, and murine typhus. Common symptoms include fever, headache, and a rash. Typically these begin one to two weeks after exposure. The diseases are caused by specific types of bacterial infection. Epidemic typhus is due to ''Rickettsia prowazekii'' spread by body lice, scrub typhus is due to ''Orientia tsutsugamushi'' spread by chiggers, and murine typhus is due to ''Rickettsia typhi'' spread by fleas. Vaccines have been developed, but none are commercially available. Prevention is achieved by reducing exposure to the organisms that spread the disease. Treatment is with the antibiotic doxycycline. Epidemic typhus generally occurs in outbreaks when poor sanitary conditions and crowding are present. While once common, it is now rare. Scrub typhus occurs in Southeast Asia, Japan, and northern Australia. Murine typhus occurs in tropical and subtropical areas of the worl ...
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Carbon Dioxide
Carbon dioxide (chemical formula ) is a chemical compound made up of molecules that each have one carbon atom covalently double bonded to two oxygen atoms. It is found in the gas state at room temperature. In the air, carbon dioxide is transparent to visible light but absorbs infrared radiation, acting as a greenhouse gas. It is a trace gas in Earth's atmosphere at 421 parts per million (ppm), or about 0.04% by volume (as of May 2022), having risen from pre-industrial levels of 280 ppm. Burning fossil fuels is the primary cause of these increased CO2 concentrations and also the primary cause of climate change.IPCC (2022Summary for policy makersiClimate Change 2022: Mitigation of Climate Change. Contribution of Working Group III to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change Cambridge University Press, Cambridge, United Kingdom and New York, NY, USA Carbon dioxide is soluble in water and is found in groundwater, lakes, ice caps, ...
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Erasmus Darwin
Erasmus Robert Darwin (12 December 173118 April 1802) was an English physician. One of the key thinkers of the Midlands Enlightenment, he was also a natural philosopher, physiologist, slave-trade abolitionist, inventor, and poet. His poems included much natural history, including a statement of evolution and the relatedness of all forms of life. He was a member of the Darwin–Wedgwood family, which includes his grandsons Charles Darwin and Francis Galton. Darwin was a founding member of the Lunar Society of Birmingham, a discussion group of pioneering industrialists and natural philosophers. He turned down an invitation from George III to become Physician to the King. Early life and education Darwin was born in 1731 at Elston Hall, Nottinghamshire, near Newark-on-Trent, England, the youngest of seven children of Robert Darwin of Elston (1682–1754), a lawyer and physician, and his wife Elizabeth Hill (1702–97). The name Erasmus had been used by a number of his f ...
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Pulmonary Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active TB is ba ...
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Watt Apparatus 1
The watt (symbol: W) is the unit of power or radiant flux in the International System of Units (SI), equal to 1 joule per second or 1 kg⋅m2⋅s−3. It is used to quantify the rate of energy transfer. The watt is named after James Watt (1736–1819), an 18th-century Scottish inventor, mechanical engineer, and chemist who improved the Newcomen engine with his own steam engine in 1776. Watt's invention was fundamental for the Industrial Revolution. Overview When an object's velocity is held constant at one metre per second against a constant opposing force of one newton, the rate at which work is done is one watt. : \mathrm In terms of electromagnetism, one watt is the rate at which electrical work is performed when a current of one ampere (A) flows across an electrical potential difference of one volt (V), meaning the watt is equivalent to the volt-ampere (the latter unit, however, is used for a different quantity from the real power of an electrical circuit). : \mathr ...
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Nitrous Oxide
Nitrous oxide (dinitrogen oxide or dinitrogen monoxide), commonly known as laughing gas, nitrous, or nos, is a chemical compound, an oxide of nitrogen with the formula . At room temperature, it is a colourless non-flammable gas, and has a slightly sweet scent and taste. At elevated temperatures, nitrous oxide is a powerful oxidiser similar to molecular oxygen. Nitrous oxide has significant medical uses, especially in surgery and dentistry, for its anaesthetic and pain-reducing effects. Its colloquial name, "laughing gas", coined by Humphry Davy, is due to the euphoric effects upon inhaling it, a property that has led to its recreational use as a dissociative anaesthetic. It is on the World Health Organization's List of Essential Medicines. It is also used as an oxidiser in rocket propellants, and in motor racing to increase the power output of engines. Nitrous oxide's atmospheric concentration reached 333 parts per billion (ppb) in 2020, increasing at a rate of abo ...
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Davies Giddy
Davies Gilbert (born Davies Giddy, 6 March 1767 – 24 December 1839) was an English engineer, author, and politician. He was elected to the Royal Society on 17 November 1791 and served as President of the Royal Society from 1827 to 1830. He changed his name to Gilbert in 1817. Biography Davies Giddy was born on 6 March 1767, the second of the three children of Reverend Edward Giddy, curate of St Erth's church, and his wife Catherine, daughter of Henry Davies of Tredrea, St Erth in Cornwall. His parents' first child, also Davies by forename, died within 24 hours of birth in 1766, and their third child, Mary Philippa Davies Giddy (known as Philippa) was born in 1769. The Giddy family moved to Penzance, living on Chapel Street in 1775, until Giddy's mother Catherine inherited the family home of Tredrea back in St Erth. By 1780 the family returned to St Erth, and Davies was taught by his father, alongside his sister Philippa. Davies Giddy would later adopt Gilbert as his surnam ...
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Dowry Square
Dowry Square is in the Hotwells area of Bristol. It was laid out in 1727 by George Tully and building continued until 1750. The houses are three-storeyed with attics, simply detailed and with channelled pilasters to the party walls. In 1799 Dr Thomas Beddoes opened a laboratory in Dowry Square as the ''Pneumatic Institution'' where he worked with Sir Humphry Davy. Architecture Many of the buildings have been designated by English Heritage as grade II* or II listed buildings. * No 1 (grade II) * No 2 (grade II) * No 3 (grade II) * No 4 (grade II*) * No 5 (grade II) * No 6 (grade II*) * No 8 (grade II) * No 9 (grade II*) * No 7 (grade II*) * No 10 (grade II*) * No 11 (grade II*) * No 12 (grade II*) * No 13 (grade II) * Nos 14&15 (grade II) * No 16 York House (grade II) * K6 Telephone Kiosk The red telephone box, a telephone booth, telephone kiosk for a payphone, public telephone designed by Giles Gilbert Scott, Sir Giles Gilbert Scott, is a familiar sight on t ...
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Hydrogen
Hydrogen is the chemical element with the symbol H and atomic number 1. Hydrogen is the lightest element. At standard conditions hydrogen is a gas of diatomic molecules having the formula . It is colorless, odorless, tasteless, non-toxic, and highly combustible. Hydrogen is the most abundant chemical substance in the universe, constituting roughly 75% of all normal matter.However, most of the universe's mass is not in the form of baryons or chemical elements. See dark matter and dark energy. Stars such as the Sun are mainly composed of hydrogen in the plasma state. Most of the hydrogen on Earth exists in molecular forms such as water and organic compounds. For the most common isotope of hydrogen (symbol 1H) each atom has one proton, one electron, and no neutrons. In the early universe, the formation of protons, the nuclei of hydrogen, occurred during the first second after the Big Bang. The emergence of neutral hydrogen atoms throughout the universe occurred about 370,000 ...
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