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Plexion
The drug combination sulfacetamide/sulfur is a topical acne medication manufactured by Medicis under the trade name Plexion and also available under other trade names such as Clenia, Prascion, and Avar. It combines sodium sulfacetamide, a sulfonamide antibiotic, and sulfur, a keratolytic agent. It is available in four formulations: as a cleansing cloth, cleanser, topical suspension, and as a facial mask. The sulfacetamide inhibits the growth of the bacterium ''Cutibacterium acnes ''Cutibacterium acnes'' (formerly ''Propionibacterium acnes'') is the relatively slow-growing, typically aerotolerant anaerobic, gram-positive bacterium (rod) linked to the skin condition of acne; it can also cause chronic blepharitis and endopht ...'' that is associated with acne, while sulfur facilitates the removal of dead skin cells to prevent clogged pores. References Anti-acne preparations Combination drugs {{dermatologic-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sulfacetamide
Sulfacetamide is a sulfonamide antibiotic. Uses Sulfacetamide 10% topical lotion, sold under the brand name Klaron or Ovace, is approved for the treatment of acne and seborrheic dermatitis. When combined with sulfur, it is sold under the brand names Plexion, Clenia, Prascion, and Avar, which contain 10% sulfacetamide and 5% sulfur. Sulfacetamide has been investigated for use in the treatment of pityriasis versicolor and rosacea. It also has anti-inflammatory properties when used to treat blepharitis or conjunctivitis (in eye-drop solution). It is believed to work by limiting the presence of folic acid which bacteria need to survive. It has been suggested that sulfacetamide may also serve as a treatment for mild forms of hidradenitis suppurativa. Sulfacetamide has antibacterial activity and is used to control acne. Products containing sulfacetamide and sulfur (a keratolytic) are commonly promoted for the treatment of acne rosacea (rosacea with papules, pustules, or both). Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sulfonamide (medicine)
Sulfonamide is a functional group (a part of a molecule) that is the basis of several groups of drugs, which are called sulphonamides, sulfa drugs or sulpha drugs. The original antibacterial sulfonamides are synthetic (nonantibiotic) antimicrobial agents that contain the sulfonamide group. Some sulfonamides are also devoid of antibacterial activity, e.g., the anticonvulsant sultiame. The sulfonylureas and thiazide diuretics are newer drug groups based upon the antibacterial sulfonamides. Allergies to sulfonamides are common. The overall incidence of adverse drug reactions to sulfa antibiotics is approximately 3%, close to penicillin; hence medications containing sulfonamides are prescribed carefully. Sulfonamide drugs were the first broadly effective antibacterials to be used systemically, and paved the way for the antibiotic revolution in medicine. Function In bacteria, antibacterial sulfonamides act as competitive inhibitors of the enzyme dihydropteroate synthase (DHP ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Keratolytic
Keratolytic () therapy is a type of medical treatment to remove warts, calluses and other lesions in which the epidermis produces excess skin. In this therapy, acidic topical medicines, such as Whitfield's ointment or Jessner's solution, are applied to the lesion in order to thin the skin on and around it. This therapy causes the outer layer of the skin to loosen and shed. Keratolytics can also be used to soften keratin, a major component of the skin. This serves to improve the skin's moisture binding capacity, which is beneficial in the treatment of dry skin. Such agents (keratolytics) include alkali (by swelling and hydrolysis of skin), salicylic acid, urea, lactic acid, allantoin, glycolic acid, and trichloroacetic acid. While cytostatic agents such as zinc pyrithione are first line, keratolytics ( salicylic acid and sulfur) can also be used in the treatment of dandruff and seborrheic dermatitis. Sulfur and salicylic acid can also be used to effectively treat acne and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cutibacterium Acnes
''Cutibacterium acnes'' (formerly ''Propionibacterium acnes'') is the relatively slow-growing, typically aerotolerant Anaerobic organism, anaerobic, gram-positive bacterium (rod) linked to the skin condition of acne vulgaris, acne; it can also cause chronic blepharitis and endophthalmitis, the latter particularly following intraocular surgery. Its genome has been sequenced and a study has shown several genes can generate enzymes for degrading skin and proteins that may be immunogenic (activating the immune system). The species is largely commensalism, commensal and part of the skin flora present on most healthy adult humans' skin. It is usually just barely detectable on the skin of healthy preadolescents. It lives, among other things, primarily on fatty acids in sebum secreted by sebaceous glands in the Hair follicle, follicles. It may also be found throughout the gastrointestinal tract. Originally identified as ''Bacillus acnes'', it was later named ''Propionibacterium acnes'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bacterium
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria are vital in many stages of the nutrient cycle by recycling nutrients such as the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in symbiotic and parasitic relationshi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Facial Mask
A facial mask is a creamy or thick pasted mask applied to clean or smoothen the face. Facial masks often contain minerals, vitamins, and fruit extracts, such as cactus and cucumber. A sheet mask is a piece of paper, cellulose or fabric used to apply a facial mask. The first facial mask was invented in Ohio, United States, during the 19th century by Madame Rowley. It was called the "Toilet Mask" or the first "face glove", and was advertised as able to 'bleach, purify and preserve the complexion' of the skin. It was patented in 1875. There are different kinds of masks for different purposes; some are deep cleansing for cleaning the pores. The perceived effect of a facial mask treatment can be revitalizing, rejuvenating or refreshing. Facial masks can be used on both men and women. Although widely believed to provide tighter pores, increased skin clarity, and a reduction in facial skin wrinkles, masks have not been shown to be any more effective at accomplishing these things than a s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Suspension (chemistry)
In chemistry, a suspension is a heterogeneous mixture of a fluid that contains solid particles sufficiently large for sedimentation. The particles may be visible to the naked eye, usually must be larger than one micrometer, and will eventually settle, although the mixture is only classified as a suspension when and while the particles have not settled out. Properties A suspension is a heterogeneous mixture in which the solute particles do not dissolve, but get suspended throughout the bulk of the solvent, left floating around freely in the medium. The internal phase (solid) is dispersed throughout the external phase (fluid) through mechanical agitation, with the use of certain excipients or suspending agents. An example of a suspension would be sand in water. The suspended particles are visible under a microscope and will settle over time if left undisturbed. This distinguishes a suspension from a colloid, in which the colloid particles are smaller and do not settle. Colloids a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cleanser
The term cleanser refers to a product that cleans or removes dirt or other substances. A cleanser could be a detergent, and there are many types of cleansers that are produced with a specific objective or focus. For instance a degreaser or carburetor cleanser used in automotive mechanics for cleaning certain engine and car parts. Other varieties include the ones used in cosmetology, dermatology or general skin care. In this case, a cleanser is a facial care product that is used to remove make-up, skin care product residue, microbes, dead skin cells, oils, sweat, dirt and other types of daily pollutants from the face. These washing aids help prevent filth-accumulation, infections, pores clogs, irritation and cosmetic issues like dullness from dead skin buildup & excessive skin shine from sebum buildup. This can also aid in preventing or treating certain skin conditions; such as acne. Cleansing is the first step in a skin care regimen and can be used in addition of a toner and moist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wet Wipe
A wet wipe, also known as a wet towel or a moist towelette, disposable wipe, disinfecting wipe, or a baby wipe (in specific circumstances) is a small to medium-sized moistened piece of plastic or cloth that either comes folded and individually wrapped for convenience or, in the case of dispensers, as a large roll with individual wipes that can be torn off. Wet wipes are used for cleaning purposes like personal hygiene and household cleaning; each is a separate product depending on the chemicals added and medical or office cleaning wipes are not intended for skin hygiene. In 2013, owing to increasing sales of the product in affluent countries, Consumer Reports reported that efforts to make the wipes "flushable" down the toilet had not entirely succeeded, according to their test. Invention American Arthur Julius is seen as the inventor of wet wipes. Julius worked in the cosmetics industry and in 1957, adjusted a soap portioning machine, putting it in a loft in Manhattan. Julius ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmaceutical Formulation
Pharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product. The word ''formulation'' is often used in a way that includes dosage form. Stages and timeline Formulation studies involve developing a preparation of the drug which is both stable and acceptable to the patient. For orally administered drugs, this usually involves incorporating the drug into a tablet or a capsule. It is important to make the distinction that a tablet contains a variety of other potentially inert substances apart from the drug itself, and studies have to be carried out to ensure that the encapsulated drug is compatible with these other substances in a way that does not cause harm, whether direct or indirect. Preformulation involves the characterization of a drug's physical, chemical, and mechanical properties in order to choose what other ingredients (excipients) should be used in the pre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sulfur (pharmacy)
Sulfur is used in pharmaceutical skin preparations for the treatment of acne and other conditions. it acts as a keratolytic agent and also kills bacteria, fungi, scabies mites and other parasites. Chemically, it is the naturally occurring octasulfur (S8). Forms and uses * ''Flower of sulfur'' or ''sublimed sulfur'' (Latin: ''sulfur sublimatum'') is the naturally occurring, unpurified form. It comes in yellow flakes and has been used in traditional and alternative medicine for humans and animals, as well as in alchemy and sulfuring fruit before drying. * ''Purified sulfur'' (''sulfur depuratum'') is prepared by washing sublimed sulfur with ammonia. It is a fine yellow powder. It was formerly used as a laxative, but this application is rare today. * ''Precipitated sulfur'' (''sulfur praecipitatum'') is prepared by boiling sulfur and calcium oxide in water and then precipitating with hydrochloric acid. It, too, is a fine yellow powder. * ''Colloidal sulfur'' (''sulfur colloidale'') ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Keratolytic
Keratolytic () therapy is a type of medical treatment to remove warts, calluses and other lesions in which the epidermis produces excess skin. In this therapy, acidic topical medicines, such as Whitfield's ointment or Jessner's solution, are applied to the lesion in order to thin the skin on and around it. This therapy causes the outer layer of the skin to loosen and shed. Keratolytics can also be used to soften keratin, a major component of the skin. This serves to improve the skin's moisture binding capacity, which is beneficial in the treatment of dry skin. Such agents (keratolytics) include alkali (by swelling and hydrolysis of skin), salicylic acid, urea, lactic acid, allantoin, glycolic acid, and trichloroacetic acid. While cytostatic agents such as zinc pyrithione are first line, keratolytics ( salicylic acid and sulfur) can also be used in the treatment of dandruff and seborrheic dermatitis. Sulfur and salicylic acid can also be used to effectively treat acne and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
