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Place Field
A place cell is a kind of pyramidal neuron in the hippocampus that becomes active when an animal enters a particular place in its environment, which is known as the place field. Place cells are thought to act collectively as a cognitive representation of a specific location in space, known as a cognitive map. Place cells work with other types of neurons in the hippocampus and surrounding regions to perform this kind of spatial processing. They have been found in a variety of animals, including rodents, bats, monkeys and humans. Place-cell firing patterns are often determined by stimuli in the environment such as visual landmarks, and olfactory and vestibular stimuli. Place cells have the ability to suddenly change their firing pattern from one pattern to another, a phenomenon known as remapping. This remapping may occur in either some of the place cells or in all place cells at once. It may be caused by a number of changes, such as in the odor of the environment. Place cells ar ...
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Place Cell Spiking Activity Example
Place may refer to: Geography * Place (United States Census Bureau), defined as any concentration of population ** Census-designated place, a populated area lacking its own municipal government * "Place", a type of street or road name ** Often implies a dead end (street) or cul-de-sac * Place, based on the Cornish word "plas" meaning mansion * Place, a populated place, an area of human settlement ** Incorporated place (see municipal corporation), a populated area with its own municipal government * Location (geography), an area with definite or indefinite boundaries or a portion of space which has a name in an area Placenames * Placé, a commune in Pays de la Loire, Paris, France * Plače, a small settlement in Slovenia * Place (Mysia), a town of ancient Mysia, Anatolia, now in Turkey * Place, New Hampshire, a location in the United States * Place House, a 16th-century mansion largely remodelled in the 19th century, in Fowey, Cornwall * Place House, a 19th-century mansion on ...
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Hebbian Theory
Hebbian theory is a neuroscientific theory claiming that an increase in synaptic efficacy arises from a presynaptic cell's repeated and persistent stimulation of a postsynaptic cell. It is an attempt to explain synaptic plasticity, the adaptation of brain neurons during the learning process. It was introduced by Donald Hebb in his 1949 book ''The Organization of Behavior.'' The theory is also called Hebb's rule, Hebb's postulate, and cell assembly theory. Hebb states it as follows: Let us assume that the persistence or repetition of a reverberatory activity (or "trace") tends to induce lasting cellular changes that add to its stability. ... When an axon of cell ''A'' is near enough to excite a cell ''B'' and repeatedly or persistently takes part in firing it, some growth process or metabolic change takes place in one or both cells such that ''A''’s efficiency, as one of the cells firing ''B'', is increased. The theory is often summarized as "Cells that fire together wire toget ...
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Vestibular System
The vestibular system, in vertebrates, is a sensory system that creates the sense of balance and spatial orientation for the purpose of coordinating movement with balance. Together with the cochlea, a part of the auditory system, it constitutes the labyrinth of the inner ear in most mammals. As movements consist of rotations and translations, the vestibular system comprises two components: the semicircular canals, which indicate rotational movements; and the otoliths, which indicate linear accelerations. The vestibular system sends signals primarily to the neural structures that control eye movement; these provide the anatomical basis of the vestibulo-ocular reflex, which is required for clear vision. Signals are also sent to the muscles that keep an animal upright and in general control posture; these provide the anatomical means required to enable an animal to maintain its desired position in space. The brain uses information from the vestibular system in the head and fro ...
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Olfactory System
The olfactory system, or sense of smell, is the sensory system used for smelling (olfaction). Olfaction is one of the special senses, that have directly associated specific organs. Most mammals and reptiles have a main olfactory system and an accessory olfactory system. The main olfactory system detects airborne substances, while the accessory system senses fluid-phase stimuli. The senses of smell and taste (gustatory system) are often referred to together as the chemosensory system, because they both give the brain information about the chemical composition of objects through a process called transduction. Structure Peripheral The peripheral olfactory system consists mainly of the nostrils, ethmoid bone, nasal cavity, and the olfactory epithelium (layers of thin tissue covered in mucus that line the nasal cavity). The primary components of the layers of epithelial tissue are the mucous membranes, olfactory glands, olfactory neurons, and nerve fibers of the olfactory nerves. ...
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Entorhinal Cortex
The entorhinal cortex (EC) is an area of the brain's allocortex, located in the medial temporal lobe, whose functions include being a widespread network hub for memory, navigation, and the perception of time.Integrating time from experience in the lateral entorhinal cortex Albert Tsao, Jørgen Sugar, Li Lu, Cheng Wang, James J. Knierim, May-Britt Moser & Edvard I. Moser Naturevolume 561, pages57–62 (2018) The EC is the main interface between the hippocampus and neocortex. The EC-hippocampus system plays an important role in declarative (autobiographical/episodic/semantic) memories and in particular spatial memories including memory formation, memory consolidation, and memory optimization in sleep. The EC is also responsible for the pre-processing (familiarity) of the input signals in the reflex nictitating membrane response of classical trace conditioning; the association of impulses from the eye and the ear occurs in the entorhinal cortex. Structure In rodents, the EC ...
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Successor Representation
Successor may refer to: * An entity that comes after another (see Succession (other)) Film and TV * ''The Successor'' (film), a 1996 film including Laura Girling * ''The Successor'' (TV program), a 2007 Israeli television program Music * ''Successor'' (EP), an EP by Sonata Arctica * ''Successor'' (album), an album by Dedekind Cut Mathematics * A successor cardinal * A successor ordinal * The successor function, the primitive defined as S(n) = n + 1 * A successor (graph theory), a node following the current one in a path Other * ''The Successor'' (novel), a 2003 novel by Ismail Kadare * The Diadochi, or Successors to Alexander the Great * Successor (horse), an American Thoroughbred racehorse * ''Successor'', the working name for the class of British ballistic missile submarines, since renamed the ''Dreadnought''-class * Khalifa, a Muslim who is considered a political-religious successor to the Islamic prophet Muhammad * Spiritual successor A spiritual successor ( ...
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Radial Arm Maze
The radial arm maze was designed by Olton and Samuelson in 1976 to measure spatial learning and memory in rats. The original apparatus consists of eight equidistantly spaced arms, each about 4 feet long, and all radiating from a small circular central platform (later versions have used as few as three and as many as 48 arms). At the end of each arm there is a food site, the contents of which are not visible from the central platform. Two types of memory that are assessed during the performance in this task are reference memory and working memory. Reference memory is assessed when the rats only visit the arms of the maze which contains the reward. The failure to do so will result in reference memory error. Working memory is assessed when the rats enter each arm a single time. Re-entry into the arms would result in a working memory error. The design ensures that, after checking for food at the end of each arm, the rat is always forced to return to the central platform before making ...
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Phase Precession
Phase precession is a neurophysiological process in which the time of firing of action potentials by individual neurons occurs progressively earlier in relation to the phase of the local field potential oscillation with each successive cycle. In place cells, a type of neuron found in the hippocampal region of the brain, phase precession is believed to play a major role in the neural coding of information. John O'Keefe, who later shared the 2014 Nobel Prize in Physiology or Medicine for his discovery that place cells help form a "map" of the body's position in space, co-discovered phase precession with Michael Recce in 1993. Place cells Pyramidal cells in the hippocampus called place cells play a significant role in self-location during movement over short distances. As a rat moves along a path, individual place cells fire action potentials at an increased rate at particular positions along the path, termed "place fields". Each place cell's maximum firing ratewith action pote ...
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Theta Wave
Theta waves generate the theta rhythm, a neural oscillation in the brain that underlies various aspects of cognition and behavior, including learning, memory, and spatial navigation in many animals. It can be recorded using various electrophysiological methods, such as electroencephalogram (EEG), recorded either from inside the brain or from electrodes attached to the scalp. At least two types of theta rhythm have been described. The hippocampal theta rhythm is a strong oscillation that can be observed in the hippocampus and other brain structures in numerous species of mammals including rodents, rabbits, dogs, cats, and marsupials. ''"Cortical theta rhythms"'' are low-frequency components of scalp EEG, usually recorded from humans. Theta rhythms can be quantified using quantitative electroencephalography (qEEG) using freely available toolboxes, such as, EEGLAB or the Neurophysiological Biomarker Toolbox (NBT). In rats, theta wave rhythmicity is easily observed in the hippoca ...
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Place Cel Remapping
Place may refer to: Geography * Place (United States Census Bureau), defined as any concentration of population ** Census-designated place, a populated area lacking its own municipal government * "Place", a type of street or road name ** Often implies a dead end (street) or cul-de-sac * Place, based on the Cornish word "plas" meaning mansion * Place, a populated place, an area of human settlement ** Incorporated place (see municipal corporation), a populated area with its own municipal government * Location (geography), an area with definite or indefinite boundaries or a portion of space which has a name in an area Placenames * Placé, a commune in Pays de la Loire, Paris, France * Plače, a small settlement in Slovenia * Place (Mysia), a town of ancient Mysia, Anatolia, now in Turkey * Place, New Hampshire, a location in the United States * Place House, a 16th-century mansion largely remodelled in the 19th century, in Fowey, Cornwall * Place House, a 19th-century mansion ...
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Allocentric Navigation
Allothetic means being centred in people or places other than oneself. It has been defined as a process of "determining and maintaining a course or trajectory from one place to another. It can be used as a navigational strategy among animals to aid in their survival. It can also be a source of information for machines, particularly those biologically-inspired models and is provided by a set of laser rangefinders, sonars, or vision. Allothetic is used in navigation models (e.g., of a rat in a maze) as in the phrase "allothetic map" to indicate that a global map, not orientated or centred on the subject was used, rather than idiothetic, which means a navigation system centred on the subject. Directional information may be sourced from familiar reference points such as the sun, stars, or the Earth's magnetic field. Allothetic cues are often employed with idiothetic information to achieve spatial behavior. Their characteristics are complementary such as the way the latter can help addr ...
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